JP2020527579A5 - - Google Patents
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- Publication number
- JP2020527579A5 JP2020527579A5 JP2020502422A JP2020502422A JP2020527579A5 JP 2020527579 A5 JP2020527579 A5 JP 2020527579A5 JP 2020502422 A JP2020502422 A JP 2020502422A JP 2020502422 A JP2020502422 A JP 2020502422A JP 2020527579 A5 JP2020527579 A5 JP 2020527579A5
- Authority
- JP
- Japan
- Prior art keywords
- synthetic
- linker
- growth factor
- sequence
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762533901P | 2017-07-18 | 2017-07-18 | |
| US62/533,901 | 2017-07-18 | ||
| PCT/IB2018/000898 WO2019016597A2 (en) | 2017-07-18 | 2018-07-18 | SYNTHETIC PROTEINS AND THEIR THERAPEUTIC USES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020527579A JP2020527579A (ja) | 2020-09-10 |
| JP2020527579A5 true JP2020527579A5 (https=) | 2021-08-26 |
| JP7751357B2 JP7751357B2 (ja) | 2025-10-08 |
Family
ID=63857968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502422A Active JP7751357B2 (ja) | 2017-07-18 | 2018-07-18 | 合成タンパク質およびその治療学的用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12134662B2 (https=) |
| EP (1) | EP3655025A2 (https=) |
| JP (1) | JP7751357B2 (https=) |
| KR (1) | KR102903351B1 (https=) |
| CN (1) | CN111246878A (https=) |
| AU (1) | AU2018304957B2 (https=) |
| BR (1) | BR112020001045A2 (https=) |
| CA (1) | CA3070034A1 (https=) |
| IL (2) | IL300235A (https=) |
| MX (1) | MX2020000636A (https=) |
| RU (1) | RU2020106669A (https=) |
| WO (1) | WO2019016597A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112996534B (zh) | 2018-08-07 | 2025-11-18 | 因斯瑞拜奥有限公司 | 结合间变性淋巴瘤激酶抑制剂进行egf/egfr通路抑制的方法和组合物 |
| AU2020301638A1 (en) * | 2019-06-25 | 2022-02-17 | In3Bio Ltd. | Stabilized chimeric synthetic proteins and therapeutic uses thereof |
| CN115379851A (zh) * | 2019-11-07 | 2022-11-22 | 因斯瑞拜奥有限公司 | 使用生长因子抗体与非酪氨酸靶向激酶抑制剂的组合的方法和组合物 |
| MX2024005177A (es) | 2021-10-28 | 2024-08-27 | In3Bio Ltd | Métodos de uso de anticuerpos anti-fce para aumentar la actividad de los inhibidores de braf y kras. |
| USD1055117S1 (en) | 2022-12-29 | 2024-12-24 | Samsung Electronics Co., Ltd. | Refrigerator |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238190A (en) | 1963-10-23 | 1966-03-01 | Madaus & Co K G Fa Dr | Aescin recovery |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| CA2261433A1 (en) | 1993-12-09 | 1995-06-10 | Belinda Sanchez Ramirez | Composition comprising autologous epidermal growth factor |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| JPH10147952A (ja) | 1996-11-18 | 1998-06-02 | Komatsu Ltd | ブルドーザのドージング装置 |
| US6645495B1 (en) | 1997-08-29 | 2003-11-11 | Antigenics, Inc. | Compositions of saponin adjuvants and excipients |
| DE60014076T2 (de) | 1999-04-19 | 2005-10-13 | Glaxosmithkline Biologicals S.A. | Adjuvans-zusammensetzung, enthaltend saponin und ein immunstimulatorisches oligonukleotid |
| CU22999A1 (es) | 2001-12-04 | 2004-10-12 | Centro Inmunologia Molecular | Método de tratamiento de enfermedades malignas e infecciosas crónicas |
| JP3855886B2 (ja) | 2002-08-29 | 2006-12-13 | トヨタ自動車株式会社 | 路面状態変化推定装置およびこれを搭載する自動車 |
| JP4623625B2 (ja) * | 2003-07-24 | 2011-02-02 | 株式会社AMBiS | ヘテロ型５量体組換えワクチン |
| WO2007109673A2 (en) * | 2006-03-20 | 2007-09-27 | Stanford University | Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor |
| KR102274211B1 (ko) * | 2011-11-23 | 2021-07-09 | 인3바이오 리미티드 | 재조합 단백질 및 그들의 치료적 용도 |
| CN111978409B (zh) * | 2013-03-15 | 2024-01-26 | 因斯瑞拜奥有限公司 | 自组装合成蛋白 |
| US12595297B2 (en) * | 2015-05-12 | 2026-04-07 | In3Bio Ltd. | Methods and compositions for inhibition of EGF/EGFR pathway in combination with tyrosine kinase inhibitors |
| FI3345613T3 (fi) * | 2015-09-01 | 2023-07-28 | Il Dong Pharma | Koostumus käytettäväksi syövän tai angiogeneesiin liittyvän sairauden hoidossa käsittäen tuumoriin penetroituvan peptidin ja VEGF-estäjän fuusioproteiinin |
-
2018
- 2018-07-18 CN CN201880053878.8A patent/CN111246878A/zh active Pending
- 2018-07-18 US US16/631,690 patent/US12134662B2/en active Active
- 2018-07-18 WO PCT/IB2018/000898 patent/WO2019016597A2/en not_active Ceased
- 2018-07-18 RU RU2020106669A patent/RU2020106669A/ru unknown
- 2018-07-18 CA CA3070034A patent/CA3070034A1/en active Pending
- 2018-07-18 MX MX2020000636A patent/MX2020000636A/es unknown
- 2018-07-18 IL IL300235A patent/IL300235A/en unknown
- 2018-07-18 KR KR1020207004272A patent/KR102903351B1/ko active Active
- 2018-07-18 BR BR112020001045-6A patent/BR112020001045A2/pt unknown
- 2018-07-18 EP EP18786382.4A patent/EP3655025A2/en active Pending
- 2018-07-18 JP JP2020502422A patent/JP7751357B2/ja active Active
- 2018-07-18 AU AU2018304957A patent/AU2018304957B2/en active Active
-
2020
- 2020-01-15 IL IL272050A patent/IL272050B2/en unknown
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