JP2020527579A5 - - Google Patents
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- Publication number
- JP2020527579A5 JP2020527579A5 JP2020502422A JP2020502422A JP2020527579A5 JP 2020527579 A5 JP2020527579 A5 JP 2020527579A5 JP 2020502422 A JP2020502422 A JP 2020502422A JP 2020502422 A JP2020502422 A JP 2020502422A JP 2020527579 A5 JP2020527579 A5 JP 2020527579A5
- Authority
- JP
- Japan
- Prior art keywords
- synthetic
- linker
- growth factor
- sequence
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762533901P | 2017-07-18 | 2017-07-18 | |
| US62/533,901 | 2017-07-18 | ||
| PCT/IB2018/000898 WO2019016597A2 (en) | 2017-07-18 | 2018-07-18 | SYNTHETIC PROTEINS AND THEIR THERAPEUTIC USES |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020527579A JP2020527579A (ja) | 2020-09-10 |
| JP2020527579A5 true JP2020527579A5 (https=) | 2021-08-26 |
| JP7751357B2 JP7751357B2 (ja) | 2025-10-08 |
Family
ID=63857968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502422A Active JP7751357B2 (ja) | 2017-07-18 | 2018-07-18 | 合成タンパク質およびその治療学的用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12134662B2 (https=) |
| EP (1) | EP3655025A2 (https=) |
| JP (1) | JP7751357B2 (https=) |
| KR (1) | KR102903351B1 (https=) |
| CN (1) | CN111246878A (https=) |
| AU (1) | AU2018304957B2 (https=) |
| BR (1) | BR112020001045A2 (https=) |
| CA (1) | CA3070034A1 (https=) |
| IL (2) | IL300235A (https=) |
| MX (1) | MX2020000636A (https=) |
| RU (1) | RU2020106669A (https=) |
| WO (1) | WO2019016597A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3108236A1 (en) | 2018-08-07 | 2020-02-13 | In3Bio Ltd. | Methods and compositions for inhibition of egf/egfr pathway in combination with anaplastic lymphoma kinase inhibitors |
| CN114269792B (zh) * | 2019-06-25 | 2025-08-08 | 因斯瑞拜奥有限公司 | 稳定的嵌合合成蛋白及其治疗用途 |
| CN115379851A (zh) * | 2019-11-07 | 2022-11-22 | 因斯瑞拜奥有限公司 | 使用生长因子抗体与非酪氨酸靶向激酶抑制剂的组合的方法和组合物 |
| CA3236522A1 (en) | 2021-10-28 | 2023-05-04 | In3Bio Ltd. | Methods of using anti-egf antibodies to augment the activity of braf and kras inhibitors |
| USD1055117S1 (en) | 2022-12-29 | 2024-12-24 | Samsung Electronics Co., Ltd. | Refrigerator |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238190A (en) | 1963-10-23 | 1966-03-01 | Madaus & Co K G Fa Dr | Aescin recovery |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| CA2261433A1 (en) * | 1993-12-09 | 1995-06-10 | Belinda Sanchez Ramirez | Composition comprising autologous epidermal growth factor |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| JPH10147952A (ja) | 1996-11-18 | 1998-06-02 | Komatsu Ltd | ブルドーザのドージング装置 |
| CA2302522C (en) | 1997-08-29 | 2010-08-17 | Antigenics Llc | Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient |
| PT1187629E (pt) | 1999-04-19 | 2005-02-28 | Glaxosmithkline Biolog Sa | Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador |
| CU22999A1 (es) | 2001-12-04 | 2004-10-12 | Centro Inmunologia Molecular | Método de tratamiento de enfermedades malignas e infecciosas crónicas |
| JP3855886B2 (ja) | 2002-08-29 | 2006-12-13 | トヨタ自動車株式会社 | 路面状態変化推定装置およびこれを搭載する自動車 |
| JP4623625B2 (ja) * | 2003-07-24 | 2011-02-02 | 株式会社AMBiS | ヘテロ型５量体組換えワクチン |
| WO2007109673A2 (en) * | 2006-03-20 | 2007-09-27 | Stanford University | Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor |
| MX354902B (es) * | 2011-11-23 | 2018-03-23 | Bioven 3 Ltd | Proteínas recombinantes y sus usos terapéuticos. |
| EP2970409A2 (en) * | 2013-03-15 | 2016-01-20 | Bioven 3 Limited | Self-assembling synthetic proteins |
| US12595297B2 (en) * | 2015-05-12 | 2026-04-07 | In3Bio Ltd. | Methods and compositions for inhibition of EGF/EGFR pathway in combination with tyrosine kinase inhibitors |
| EP3345613B1 (en) * | 2015-09-01 | 2023-05-10 | Il Dong Pharmaceutical Co., Ltd. | Composition for use in treating cancer or an angiogenesis-related disease comprising a fusion protein of a tumor-penetrating peptide and an anti-vegf agent |
-
2018
- 2018-07-18 JP JP2020502422A patent/JP7751357B2/ja active Active
- 2018-07-18 US US16/631,690 patent/US12134662B2/en active Active
- 2018-07-18 CA CA3070034A patent/CA3070034A1/en active Pending
- 2018-07-18 BR BR112020001045-6A patent/BR112020001045A2/pt unknown
- 2018-07-18 WO PCT/IB2018/000898 patent/WO2019016597A2/en not_active Ceased
- 2018-07-18 KR KR1020207004272A patent/KR102903351B1/ko active Active
- 2018-07-18 IL IL300235A patent/IL300235A/en unknown
- 2018-07-18 AU AU2018304957A patent/AU2018304957B2/en active Active
- 2018-07-18 RU RU2020106669A patent/RU2020106669A/ru unknown
- 2018-07-18 MX MX2020000636A patent/MX2020000636A/es unknown
- 2018-07-18 EP EP18786382.4A patent/EP3655025A2/en active Pending
- 2018-07-18 CN CN201880053878.8A patent/CN111246878A/zh active Pending
-
2020
- 2020-01-15 IL IL272050A patent/IL272050B2/en unknown
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