JP2020526525A5 - - Google Patents

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Publication number
JP2020526525A5
JP2020526525A5 JP2020500617A JP2020500617A JP2020526525A5 JP 2020526525 A5 JP2020526525 A5 JP 2020526525A5 JP 2020500617 A JP2020500617 A JP 2020500617A JP 2020500617 A JP2020500617 A JP 2020500617A JP 2020526525 A5 JP2020526525 A5 JP 2020526525A5
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JP
Japan
Prior art keywords
rvwf
medicament according
bleeding
subject
days
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JP2020500617A
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English (en)
Japanese (ja)
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JP7307047B2 (ja
JP2020526525A (ja
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Priority claimed from PCT/US2018/041320 external-priority patent/WO2019010497A1/en
Publication of JP2020526525A publication Critical patent/JP2020526525A/ja
Publication of JP2020526525A5 publication Critical patent/JP2020526525A5/ja
Priority to JP2023106554A priority Critical patent/JP7641327B2/ja
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Publication of JP7307047B2 publication Critical patent/JP7307047B2/ja
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JP2020500617A 2017-07-07 2018-07-09 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 Active JP7307047B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023106554A JP7641327B2 (ja) 2017-07-07 2023-06-29 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762530027P 2017-07-07 2017-07-07
US62/530,027 2017-07-07
PCT/US2018/041320 WO2019010497A1 (en) 2017-07-07 2018-07-09 TREATMENT OF GASTROINTESTINAL BLEEDING IN PATIENTS WITH A SEVERE FORM OF VON WILLEBRAND'S DISEASE BY RECOMBINANT VWF ADMINISTRATION

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023106554A Division JP7641327B2 (ja) 2017-07-07 2023-06-29 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療

Publications (3)

Publication Number Publication Date
JP2020526525A JP2020526525A (ja) 2020-08-31
JP2020526525A5 true JP2020526525A5 (OSRAM) 2021-08-12
JP7307047B2 JP7307047B2 (ja) 2023-07-11

Family

ID=63036433

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020500617A Active JP7307047B2 (ja) 2017-07-07 2018-07-09 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療
JP2023106554A Active JP7641327B2 (ja) 2017-07-07 2023-06-29 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療

Family Applications After (1)

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JP2023106554A Active JP7641327B2 (ja) 2017-07-07 2023-06-29 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療

Country Status (16)

Country Link
US (5) US10632176B2 (OSRAM)
EP (2) EP4424366A3 (OSRAM)
JP (2) JP7307047B2 (OSRAM)
KR (2) KR102921337B1 (OSRAM)
CN (1) CN111436193A (OSRAM)
AU (2) AU2018298233B2 (OSRAM)
BR (1) BR112020000321A2 (OSRAM)
CA (1) CA3069295A1 (OSRAM)
CO (1) CO2020001322A2 (OSRAM)
DK (1) DK3648788T3 (OSRAM)
ES (1) ES2986574T3 (OSRAM)
FI (1) FI3648788T5 (OSRAM)
MX (1) MX2025012580A (OSRAM)
PL (1) PL3648788T3 (OSRAM)
PT (1) PT3648788T (OSRAM)
WO (1) WO2019010497A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3648788T3 (da) 2017-07-07 2024-08-19 Takeda Pharmaceuticals Co Behandling af gastrointestinal blødning hos patienter med svær von willebrand-sygdom ved administration af rekombinant vwf
PT3648787T (pt) 2017-07-07 2025-01-20 Takeda Pharmaceuticals Co Tratamento de doentes com doença de von willebrand grave submetidos a cirurgia eletiva por administração de vwf recombinante
BR112021015068A2 (pt) 2019-02-01 2021-10-05 Takeda Pharmaceutical Company Limited Métodos de tratamento profilático usando vwf recombinante (rvwf)
US20220395560A1 (en) * 2019-02-01 2022-12-15 Takeda Pharmaceutical Company Limited METHODS OF PROPHYLACTIC TREATMENT USING RECOMBINANT VWF (rVWF)
WO2021032646A1 (en) * 2019-08-16 2021-02-25 Octapharma Ag Stabilizing buffer for factor viii and vwf

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US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US8597910B1 (en) 1985-04-11 2013-12-03 Children's Medical Center Corporation DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells
WO1986006096A1 (en) 1985-04-11 1986-10-23 The Children's Medical Center Corporation Von willebrand factor
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
DE4435485C1 (de) 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
US6005077A (en) 1995-11-10 1999-12-21 Immuno Aktiengesellschaft Use of von willebrand factor and pharmaceutical formulation
AT403764B (de) 1996-03-15 1998-05-25 Immuno Ag Stabiler faktor viii/vwf-komplex
AT406373B (de) 1997-02-27 2000-04-25 Immuno Ag Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie
AT405403B (de) 1997-02-27 1999-08-25 Immuno Ag Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
AT405485B (de) 1997-05-28 1999-08-25 Immuno Ag Eine das vwf-propeptid enthaltende pharmazeutische präparation
US6531577B1 (en) 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
WO2004039337A2 (en) 2002-10-31 2004-05-13 Protein Design Labs, Inc. Stable liquid pharmaceutical formulation of antibodies that are prone to isomerization
WO2005012354A1 (en) 2003-07-31 2005-02-10 Zlb Behring Gmbh Method for extending the half-life of fviii
EP1593388A1 (en) 2004-05-05 2005-11-09 ZLB Behring GmbH Therapeutic plasma protein-concentrates containing von willebrand factor as high molecular weight multimers
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
BRPI0519562A2 (pt) 2004-12-27 2009-01-27 Baxter Int construÇço proteinÁcea, complexo, mÉtodo para prolongar a meia-vida in vivo de fator viii (fviii) ou um derivado biologicamente ativo do mesmo composiÇço farmacÊutica, e, mÉtodo para formar uma construÇço proteinÁcea
SI2522717T1 (sl) 2006-01-04 2014-05-30 Baxter International Inc. Mediji celične kulture brez oligopeptidov
AU2008261261B2 (en) 2007-06-13 2013-06-27 Csl Behring Gmbh Use of VWF stabilized FVIII preparations and of VWF preparations without FVIII for extravascular administration in the therapy and prophylactic treatment of bleeding disorders
AU2008323768A1 (en) 2007-11-09 2009-05-14 Baxter Healthcare S.A. Modified recombinant Factor VIII and von Willebrand Factor and methods of use
WO2009086400A2 (en) 2007-12-28 2009-07-09 Baxter International Inc. Recombinant vwf formulations
DK2865760T3 (en) 2008-06-24 2018-01-15 Csl Behring Gmbh Factor VIII, Von Willebrand Factor or complexes thereof with extended in vivo half-life
DK2349314T3 (da) 2008-10-21 2013-05-27 Baxter Int Lyofiliserede præparater af rekombinant VWF
WO2011017414A2 (en) 2009-08-04 2011-02-10 Baxter International Inc. Transgenic mouse lacking endogenous fviii and vwf - a model of hemophilia a
PT3626736T (pt) 2010-07-08 2025-08-11 Takeda Pharmaceuticals Co Método de produção de fvw recombinante de elevado peso molecular na cultura celular
KR101969515B1 (ko) 2011-06-10 2019-04-16 박스알타 인코퍼레이티드 재조합 vwf의 투여에 의한 응고 질환의 치료
CA2978374A1 (en) 2015-03-06 2016-09-15 Csl Behring Recombinant Facility Ag Modified von willebrand factor having improved half-life
DK3648788T3 (da) 2017-07-07 2024-08-19 Takeda Pharmaceuticals Co Behandling af gastrointestinal blødning hos patienter med svær von willebrand-sygdom ved administration af rekombinant vwf

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