JP2020526525A5 - - Google Patents
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- JP2020526525A5 JP2020526525A5 JP2020500617A JP2020500617A JP2020526525A5 JP 2020526525 A5 JP2020526525 A5 JP 2020526525A5 JP 2020500617 A JP2020500617 A JP 2020500617A JP 2020500617 A JP2020500617 A JP 2020500617A JP 2020526525 A5 JP2020526525 A5 JP 2020526525A5
- Authority
- JP
- Japan
- Prior art keywords
- rvwf
- medicament according
- bleeding
- subject
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023106554A JP7641327B2 (ja) | 2017-07-07 | 2023-06-29 | 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762530027P | 2017-07-07 | 2017-07-07 | |
| US62/530,027 | 2017-07-07 | ||
| PCT/US2018/041320 WO2019010497A1 (en) | 2017-07-07 | 2018-07-09 | TREATMENT OF GASTROINTESTINAL BLEEDING IN PATIENTS WITH A SEVERE FORM OF VON WILLEBRAND'S DISEASE BY RECOMBINANT VWF ADMINISTRATION |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023106554A Division JP7641327B2 (ja) | 2017-07-07 | 2023-06-29 | 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020526525A JP2020526525A (ja) | 2020-08-31 |
| JP2020526525A5 true JP2020526525A5 (OSRAM) | 2021-08-12 |
| JP7307047B2 JP7307047B2 (ja) | 2023-07-11 |
Family
ID=63036433
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020500617A Active JP7307047B2 (ja) | 2017-07-07 | 2018-07-09 | 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 |
| JP2023106554A Active JP7641327B2 (ja) | 2017-07-07 | 2023-06-29 | 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023106554A Active JP7641327B2 (ja) | 2017-07-07 | 2023-06-29 | 組換えvwfの投与による重度のフォンヴィレブランド病を患う患者における消化管出血の治療 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US10632176B2 (OSRAM) |
| EP (2) | EP4424366A3 (OSRAM) |
| JP (2) | JP7307047B2 (OSRAM) |
| KR (2) | KR102921337B1 (OSRAM) |
| CN (1) | CN111436193A (OSRAM) |
| AU (2) | AU2018298233B2 (OSRAM) |
| BR (1) | BR112020000321A2 (OSRAM) |
| CA (1) | CA3069295A1 (OSRAM) |
| CO (1) | CO2020001322A2 (OSRAM) |
| DK (1) | DK3648788T3 (OSRAM) |
| ES (1) | ES2986574T3 (OSRAM) |
| FI (1) | FI3648788T5 (OSRAM) |
| MX (1) | MX2025012580A (OSRAM) |
| PL (1) | PL3648788T3 (OSRAM) |
| PT (1) | PT3648788T (OSRAM) |
| WO (1) | WO2019010497A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3648788T3 (da) | 2017-07-07 | 2024-08-19 | Takeda Pharmaceuticals Co | Behandling af gastrointestinal blødning hos patienter med svær von willebrand-sygdom ved administration af rekombinant vwf |
| PT3648787T (pt) | 2017-07-07 | 2025-01-20 | Takeda Pharmaceuticals Co | Tratamento de doentes com doença de von willebrand grave submetidos a cirurgia eletiva por administração de vwf recombinante |
| BR112021015068A2 (pt) | 2019-02-01 | 2021-10-05 | Takeda Pharmaceutical Company Limited | Métodos de tratamento profilático usando vwf recombinante (rvwf) |
| US20220395560A1 (en) * | 2019-02-01 | 2022-12-15 | Takeda Pharmaceutical Company Limited | METHODS OF PROPHYLACTIC TREATMENT USING RECOMBINANT VWF (rVWF) |
| WO2021032646A1 (en) * | 2019-08-16 | 2021-02-25 | Octapharma Ag | Stabilizing buffer for factor viii and vwf |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US3941763A (en) | 1975-03-28 | 1976-03-02 | American Home Products Corporation | PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| US8597910B1 (en) | 1985-04-11 | 2013-12-03 | Children's Medical Center Corporation | DNA encoding Von Willebrand Factor (VWF) and methods and cells for producing VFW, and VFW produced by the DNA, methods and cells |
| WO1986006096A1 (en) | 1985-04-11 | 1986-10-23 | The Children's Medical Center Corporation | Von willebrand factor |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| DE4435485C1 (de) | 1994-10-04 | 1996-03-21 | Immuno Ag | Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor |
| US6005077A (en) | 1995-11-10 | 1999-12-21 | Immuno Aktiengesellschaft | Use of von willebrand factor and pharmaceutical formulation |
| AT403764B (de) | 1996-03-15 | 1998-05-25 | Immuno Ag | Stabiler faktor viii/vwf-komplex |
| AT406373B (de) | 1997-02-27 | 2000-04-25 | Immuno Ag | Verfahren zur reinigung von faktor viii/vwf-komplex mittels kationenaustauscherchromatographie |
| AT405403B (de) | 1997-02-27 | 1999-08-25 | Immuno Ag | Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie |
| AT405485B (de) | 1997-05-28 | 1999-08-25 | Immuno Ag | Eine das vwf-propeptid enthaltende pharmazeutische präparation |
| US6531577B1 (en) | 1997-12-15 | 2003-03-11 | Hemasure Denmark A/S | von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations |
| WO2004039337A2 (en) | 2002-10-31 | 2004-05-13 | Protein Design Labs, Inc. | Stable liquid pharmaceutical formulation of antibodies that are prone to isomerization |
| WO2005012354A1 (en) | 2003-07-31 | 2005-02-10 | Zlb Behring Gmbh | Method for extending the half-life of fviii |
| EP1593388A1 (en) | 2004-05-05 | 2005-11-09 | ZLB Behring GmbH | Therapeutic plasma protein-concentrates containing von willebrand factor as high molecular weight multimers |
| US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
| BRPI0519562A2 (pt) | 2004-12-27 | 2009-01-27 | Baxter Int | construÇço proteinÁcea, complexo, mÉtodo para prolongar a meia-vida in vivo de fator viii (fviii) ou um derivado biologicamente ativo do mesmo composiÇço farmacÊutica, e, mÉtodo para formar uma construÇço proteinÁcea |
| SI2522717T1 (sl) | 2006-01-04 | 2014-05-30 | Baxter International Inc. | Mediji celične kulture brez oligopeptidov |
| AU2008261261B2 (en) | 2007-06-13 | 2013-06-27 | Csl Behring Gmbh | Use of VWF stabilized FVIII preparations and of VWF preparations without FVIII for extravascular administration in the therapy and prophylactic treatment of bleeding disorders |
| AU2008323768A1 (en) | 2007-11-09 | 2009-05-14 | Baxter Healthcare S.A. | Modified recombinant Factor VIII and von Willebrand Factor and methods of use |
| WO2009086400A2 (en) | 2007-12-28 | 2009-07-09 | Baxter International Inc. | Recombinant vwf formulations |
| DK2865760T3 (en) | 2008-06-24 | 2018-01-15 | Csl Behring Gmbh | Factor VIII, Von Willebrand Factor or complexes thereof with extended in vivo half-life |
| DK2349314T3 (da) | 2008-10-21 | 2013-05-27 | Baxter Int | Lyofiliserede præparater af rekombinant VWF |
| WO2011017414A2 (en) | 2009-08-04 | 2011-02-10 | Baxter International Inc. | Transgenic mouse lacking endogenous fviii and vwf - a model of hemophilia a |
| PT3626736T (pt) | 2010-07-08 | 2025-08-11 | Takeda Pharmaceuticals Co | Método de produção de fvw recombinante de elevado peso molecular na cultura celular |
| KR101969515B1 (ko) | 2011-06-10 | 2019-04-16 | 박스알타 인코퍼레이티드 | 재조합 vwf의 투여에 의한 응고 질환의 치료 |
| CA2978374A1 (en) | 2015-03-06 | 2016-09-15 | Csl Behring Recombinant Facility Ag | Modified von willebrand factor having improved half-life |
| DK3648788T3 (da) | 2017-07-07 | 2024-08-19 | Takeda Pharmaceuticals Co | Behandling af gastrointestinal blødning hos patienter med svær von willebrand-sygdom ved administration af rekombinant vwf |
-
2018
- 2018-07-09 DK DK18746458.1T patent/DK3648788T3/da active
- 2018-07-09 KR KR1020207003264A patent/KR102921337B1/ko active Active
- 2018-07-09 FI FIEP18746458.1T patent/FI3648788T5/fi active
- 2018-07-09 ES ES18746458T patent/ES2986574T3/es active Active
- 2018-07-09 US US16/030,659 patent/US10632176B2/en active Active
- 2018-07-09 KR KR1020267002897A patent/KR20260037107A/ko active Pending
- 2018-07-09 PT PT187464581T patent/PT3648788T/pt unknown
- 2018-07-09 PL PL18746458.1T patent/PL3648788T3/pl unknown
- 2018-07-09 AU AU2018298233A patent/AU2018298233B2/en active Active
- 2018-07-09 CN CN201880057599.9A patent/CN111436193A/zh active Pending
- 2018-07-09 WO PCT/US2018/041320 patent/WO2019010497A1/en not_active Ceased
- 2018-07-09 CA CA3069295A patent/CA3069295A1/en active Pending
- 2018-07-09 JP JP2020500617A patent/JP7307047B2/ja active Active
- 2018-07-09 BR BR112020000321-2A patent/BR112020000321A2/pt unknown
- 2018-07-09 EP EP24176324.2A patent/EP4424366A3/en active Pending
- 2018-07-09 EP EP18746458.1A patent/EP3648788B1/en active Active
-
2020
- 2020-01-08 MX MX2025012580A patent/MX2025012580A/es unknown
- 2020-02-06 CO CONC2020/0001322A patent/CO2020001322A2/es unknown
- 2020-02-26 US US16/802,118 patent/US10905746B2/en active Active
- 2020-12-01 US US17/108,562 patent/US11529395B2/en active Active
-
2022
- 2022-12-06 US US18/062,534 patent/US12016904B2/en active Active
-
2023
- 2023-06-29 JP JP2023106554A patent/JP7641327B2/ja active Active
-
2024
- 2024-06-12 US US18/741,650 patent/US20240316160A1/en active Pending
-
2025
- 2025-07-11 AU AU2025205392A patent/AU2025205392A1/en active Pending
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