JP2020520924A5 - - Google Patents
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- Publication number
- JP2020520924A5 JP2020520924A5 JP2019563596A JP2019563596A JP2020520924A5 JP 2020520924 A5 JP2020520924 A5 JP 2020520924A5 JP 2019563596 A JP2019563596 A JP 2019563596A JP 2019563596 A JP2019563596 A JP 2019563596A JP 2020520924 A5 JP2020520924 A5 JP 2020520924A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- haloalkyl
- heterocyclyl
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(*)(*N)*=C Chemical compound *C(*)(*N)*=C 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021146775A JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762507698P | 2017-05-17 | 2017-05-17 | |
| US62/507,698 | 2017-05-17 | ||
| US201862664895P | 2018-04-30 | 2018-04-30 | |
| US62/664,895 | 2018-04-30 | ||
| PCT/US2018/033266 WO2018213632A1 (en) | 2017-05-17 | 2018-05-17 | Kinase inhibitors and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021146775A Division JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020520924A JP2020520924A (ja) | 2020-07-16 |
| JP2020520924A5 true JP2020520924A5 (enExample) | 2021-07-26 |
| JP7064512B2 JP7064512B2 (ja) | 2022-05-10 |
Family
ID=64274744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563596A Active JP7064512B2 (ja) | 2017-05-17 | 2018-05-17 | キナーゼ阻害剤およびその使用 |
| JP2021146775A Active JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021146775A Active JP7241825B2 (ja) | 2017-05-17 | 2021-09-09 | キナーゼ阻害剤およびその使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11203600B2 (enExample) |
| EP (1) | EP3624797A4 (enExample) |
| JP (2) | JP7064512B2 (enExample) |
| KR (1) | KR102638151B1 (enExample) |
| CN (3) | CN110913858B (enExample) |
| AU (1) | AU2018269743B2 (enExample) |
| BR (1) | BR112019023918A2 (enExample) |
| CA (1) | CA3063934A1 (enExample) |
| CL (1) | CL2019003263A1 (enExample) |
| CO (1) | CO2019012957A2 (enExample) |
| CR (1) | CR20190566A (enExample) |
| DO (1) | DOP2019000290A (enExample) |
| EC (1) | ECSP19089214A (enExample) |
| IL (1) | IL270648B2 (enExample) |
| MX (2) | MX2019013645A (enExample) |
| MY (1) | MY200328A (enExample) |
| PE (2) | PE20241932A1 (enExample) |
| PH (1) | PH12019550235A1 (enExample) |
| SG (1) | SG10201913927VA (enExample) |
| TW (1) | TWI794232B (enExample) |
| WO (1) | WO2018213632A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220072019A1 (en) * | 2018-10-19 | 2022-03-10 | Disarm Therapeutics, Inc. | Inhibitors of sarm1 in combination with nad+ or a nad+ precursor |
| IL291665B2 (en) * | 2019-09-27 | 2025-07-01 | Univ Texas | Inhibitors of receptor interacting protein kinase i for the treatment of disease |
| TWI873290B (zh) | 2020-02-13 | 2025-02-21 | 德商百靈佳殷格翰國際股份有限公司 | 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物 |
| WO2021187605A1 (ja) * | 2020-03-19 | 2021-09-23 | 田辺三菱製薬株式会社 | 含窒素複素環αシアノカルボニル化合物 |
| TW202214617A (zh) | 2020-06-02 | 2022-04-16 | 法商賽諾菲公司 | 作為ｒｉｐｋ１抑制劑之異㗁唑啶及其用途 |
| KR200493347Y1 (ko) | 2020-07-06 | 2021-03-17 | 박혜진 | 휴대가 용이한 마스크 |
| BR112023016539A2 (pt) * | 2021-02-19 | 2023-11-14 | Kalvista Pharmaceuticals Ltd | Inibidores do fator xiia |
| WO2022231928A1 (en) * | 2021-04-27 | 2022-11-03 | Merck Sharp & Dohme Llc | Ripk1 inhibitors and methods of use |
| EP4329765A4 (en) * | 2021-04-27 | 2025-06-11 | Merck Sharp & Dohme LLC | Phenylazepines as RIPK1 inhibitors and methods of using them |
| JP2024544533A (ja) | 2021-11-11 | 2024-12-03 | ジェンザイム・コーポレーション | Ｒｉｐｋ１阻害剤としてのイソオキサゾリジン及びその使用 |
| TW202417453A (zh) * | 2022-07-25 | 2024-05-01 | 美商戴納立製藥公司 | ４－（３，３－二氟－２，２－二甲基－丙醯基）－３，５－二氫－２ｈ－吡啶並［３，４－ｆ］［１，４］氧氮呯－９－甲腈的固體形式 |
| US20240100065A1 (en) * | 2022-08-23 | 2024-03-28 | Genzyme Corporation | Methods for treating receptor-interacting protein kinase 1-mediated diseases |
| TW202444357A (zh) * | 2023-01-23 | 2024-11-16 | 美商健臻公司 | ４－（３，３－二氟－２，２－二甲基－丙醯基）－３，５－二氫－２ｈ－吡啶并［３，４－ｆ］［１，４］氧氮呯－９－甲腈之藥品調配物 |
| TW202515552A (zh) * | 2023-06-27 | 2025-04-16 | 美商健臻公司 | 製備4-(3,3-二氟-2,2-二甲基-丙醯基)-3,5-二氫-2h-吡啶并[3,4-f][1,4]氧雜氮呯-9-腈之方法 |
| CN120365288A (zh) * | 2024-01-23 | 2025-07-25 | 南京天印健华医药科技有限公司 | 作为ripk1抑制剂的杂环化合物 |
| CN120365287A (zh) * | 2024-01-23 | 2025-07-25 | 南京天印健华医药科技有限公司 | 作为ripk1抑制剂的杂环化合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3861187B2 (ja) * | 1996-08-02 | 2006-12-20 | 住友精化株式会社 | チアゼピン誘導体の製造方法 |
| EP1329450A4 (en) | 2000-09-27 | 2005-08-31 | Ajinomoto Kk | BENZODIAZEPINE DERIVATIVE |
| RU2456287C1 (ru) * | 2011-05-20 | 2012-07-20 | Николай Филиппович Савчук | Стимуляторы секреции инкретиновых гормонов, способы их получения и применения |
| TWI549944B (zh) | 2011-07-01 | 2016-09-21 | 吉李德科學股份有限公司 | 作為離子通道調節劑之稠合雜環化合物 |
| TWI648273B (zh) * | 2013-02-15 | 2019-01-21 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺類（三） |
| CN104059068B (zh) | 2013-03-20 | 2017-02-08 | 中国科学院上海药物研究所 | β‑氨基羰基类化合物、其制备方法、药物组合物及其用途 |
| AU2016215432B2 (en) | 2015-02-02 | 2020-07-30 | Valo Early Discovery, Inc. | 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors |
| TWI730959B (zh) * | 2015-05-19 | 2021-06-21 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺 |
| EP3307739B1 (en) * | 2015-06-15 | 2020-10-07 | GlaxoSmithKline Intellectual Property Development Limited | Nrf2 regulators |
-
2018
- 2018-05-17 PE PE2024000411A patent/PE20241932A1/es unknown
- 2018-05-17 AU AU2018269743A patent/AU2018269743B2/en active Active
- 2018-05-17 WO PCT/US2018/033266 patent/WO2018213632A1/en not_active Ceased
- 2018-05-17 CR CR20190566A patent/CR20190566A/es unknown
- 2018-05-17 CN CN201880047293.5A patent/CN110913858B/zh active Active
- 2018-05-17 BR BR112019023918-9A patent/BR112019023918A2/pt not_active Application Discontinuation
- 2018-05-17 SG SG10201913927VA patent/SG10201913927VA/en unknown
- 2018-05-17 CN CN202411240962.4A patent/CN119285572A/zh active Pending
- 2018-05-17 IL IL270648A patent/IL270648B2/en unknown
- 2018-05-17 KR KR1020197036911A patent/KR102638151B1/ko active Active
- 2018-05-17 PE PE2019002424A patent/PE20200729A1/es unknown
- 2018-05-17 JP JP2019563596A patent/JP7064512B2/ja active Active
- 2018-05-17 CN CN202411240964.3A patent/CN119264073A/zh active Pending
- 2018-05-17 MY MYPI2019006664A patent/MY200328A/en unknown
- 2018-05-17 TW TW107116834A patent/TWI794232B/zh active
- 2018-05-17 CA CA3063934A patent/CA3063934A1/en active Pending
- 2018-05-17 MX MX2019013645A patent/MX2019013645A/es unknown
- 2018-05-17 EP EP18802127.3A patent/EP3624797A4/en active Pending
-
2019
- 2019-11-13 PH PH12019550235A patent/PH12019550235A1/en unknown
- 2019-11-14 US US16/684,340 patent/US11203600B2/en active Active
- 2019-11-14 MX MX2022010755A patent/MX2022010755A/es unknown
- 2019-11-14 CL CL2019003263A patent/CL2019003263A1/es unknown
- 2019-11-14 DO DO2019000290A patent/DOP2019000290A/es unknown
- 2019-11-19 CO CONC2019/0012957A patent/CO2019012957A2/es unknown
- 2019-12-16 EC ECSENADI201989214A patent/ECSP19089214A/es unknown
-
2021
- 2021-09-09 JP JP2021146775A patent/JP7241825B2/ja active Active
- 2021-10-26 US US17/511,193 patent/US12129263B2/en active Active
-
2024
- 2024-09-18 US US18/889,058 patent/US20250011338A1/en active Pending
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