JP2020520756A - リキャップ防止を備えた自動インジェクタ - Google Patents

リキャップ防止を備えた自動インジェクタ Download PDF

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Publication number
JP2020520756A
JP2020520756A JP2019564912A JP2019564912A JP2020520756A JP 2020520756 A JP2020520756 A JP 2020520756A JP 2019564912 A JP2019564912 A JP 2019564912A JP 2019564912 A JP2019564912 A JP 2019564912A JP 2020520756 A JP2020520756 A JP 2020520756A
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JP
Japan
Prior art keywords
plunger rod
syringe
automatic injector
driver
refillable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019564912A
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English (en)
Japanese (ja)
Other versions
JP2020520756A5 (enExample
Inventor
ブラビュア ヤコブセン，ペーター
ブラビュア ヤコブセン，ペーター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JP2020520756A publication Critical patent/JP2020520756A/ja
Publication of JP2020520756A5 publication Critical patent/JP2020520756A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5086—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile for indicating if defective, used, tampered with or unsterile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/002—Packages specially adapted therefor, e.g. packages for syringes or needles or kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/206—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically with automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Diabetes (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2019564912A 2017-05-23 2018-05-16 リキャップ防止を備えた自動インジェクタ Pending JP2020520756A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17172563.3 2017-05-23
EP17172563 2017-05-23
PCT/EP2018/062821 WO2018215270A2 (en) 2017-05-23 2018-05-16 Auto injector with recap prevention

Publications (2)

Publication Number Publication Date
JP2020520756A true JP2020520756A (ja) 2020-07-16
JP2020520756A5 JP2020520756A5 (enExample) 2021-07-26

Family

ID=58772476

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019564912A Pending JP2020520756A (ja) 2017-05-23 2018-05-16 リキャップ防止を備えた自動インジェクタ

Country Status (9)

Country Link
US (1) US20200108211A1 (enExample)
EP (1) EP3630233A2 (enExample)
JP (1) JP2020520756A (enExample)
CN (1) CN110913927A (enExample)
AU (1) AU2018272794A1 (enExample)
BR (1) BR112019024354A2 (enExample)
CA (1) CA3064671A1 (enExample)
RU (1) RU2019141956A (enExample)
WO (1) WO2018215270A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020520755A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 中空プランジャーロッドを備えた自動インジェクタ

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CA3099431A1 (en) 2018-05-24 2019-11-28 Novartis Ag Automatic drug delivery device
CA3218974A1 (en) * 2019-02-26 2020-09-03 Becton Dickinson France Auto-injector with actuation prevention cap
EP4076598B1 (en) 2019-12-18 2025-08-06 Novo Nordisk A/S Fixed dose injection device
CN114828922B (zh) 2019-12-18 2024-11-15 诺和诺德股份有限公司 用于递送预定固定剂量的药物递送装置
CN111407975B (zh) * 2020-03-06 2024-09-27 珠海凯生医用科技有限公司 电子式注射笔
US12005244B2 (en) 2020-03-27 2024-06-11 Medivena Sp. Z O.O. Needle-based device based on direct wing-based coupling of a needle shield to a barrel thereof and safety mechanism implemented therein
GB202006835D0 (en) * 2020-05-07 2020-06-24 Owen Mumford Ltd Injection device
GB202006836D0 (en) * 2020-05-07 2020-06-24 Owen Mumford Ltd Injection device
USD963842S1 (en) 2020-05-12 2022-09-13 Shl Medical Ag Medical injector with cap
MX2022014182A (es) * 2020-05-15 2022-12-07 Biocon Biologics Ltd Ensamble de auto-inyector.
USD955565S1 (en) * 2020-05-29 2022-06-21 Medivena Sp. Z O.O. Needle-based device with a safety mechanism
US12666232B2 (en) 2020-12-18 2026-06-23 Novartis Ag Communication module for an autoinjector
EP4112097A1 (en) * 2021-07-01 2023-01-04 Phillips-Medisize A/S Auto injector and cassette system with index ring in the cassette
EP4112101A1 (en) * 2021-07-01 2023-01-04 Phillips-Medisize A/S Auto injector with release clutch function
EP4173656A1 (en) 2021-10-27 2023-05-03 medmix Switzerland AG Needle guard, drug delivery device and method for manufacturing
CN115040725B (zh) * 2022-05-12 2025-10-28 中国人民解放军海军特色医学中心 一种适用于预灌封注射器的自动注射装置
WO2024054430A1 (en) * 2022-09-06 2024-03-14 University Hospitals Cleveland Medical Center Auto-injector
WO2025073048A1 (en) * 2023-10-04 2025-04-10 Laframboise Emalie Marie Timed automatic injection device

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JP2008220949A (ja) * 2007-03-15 2008-09-25 Bristol Myers Squibb Co 事前充填式シリンジと併用する注射器及び組み立て方法
US20130144219A1 (en) * 2010-08-19 2013-06-06 West Pharmaceutical Services, Inc. Rigid needle shield
JP2014526297A (ja) * 2011-09-09 2014-10-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 独立した針挿入による自動注射器
US20150250953A1 (en) * 2012-10-12 2015-09-10 Carebay Europe Ltd Medicament Delivery Device
JP2020520755A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 中空プランジャーロッドを備えた自動インジェクタ

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US5540664A (en) 1993-05-27 1996-07-30 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
US20050101919A1 (en) * 2003-11-07 2005-05-12 Lennart Brunnberg Device for an injector
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NZ554828A (en) 2004-12-06 2010-07-30 Washington Biotech Corp Medicine injection devices and methods
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WO2009090674A2 (en) * 2008-01-17 2009-07-23 Ashok Chaturvedi Auto venting packages
IT1398501B1 (it) 2010-03-10 2013-03-01 Menarini Int Operations Lu Sa Dispositivo autoiniettore di due dosi di farmaco
EP2438939A1 (en) 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Arrangement for coupling a plunger to either a syringe or a stopper
EP2468343A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Front end for an auto-injector
EP2692377B1 (de) * 2012-08-01 2019-11-06 TecPharma Licensing AG Injektionsvorrichtung mit Dosisanzeige zur Signalisierung des Endes der Injektion
US10314987B2 (en) * 2012-10-05 2019-06-11 Shl Medical Ag Medicament delivery device
US10092703B2 (en) * 2013-03-15 2018-10-09 Amgen Inc. Drug cassette, autoinjector, and autoinjector system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008220949A (ja) * 2007-03-15 2008-09-25 Bristol Myers Squibb Co 事前充填式シリンジと併用する注射器及び組み立て方法
US20130144219A1 (en) * 2010-08-19 2013-06-06 West Pharmaceutical Services, Inc. Rigid needle shield
JP2014526297A (ja) * 2011-09-09 2014-10-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 独立した針挿入による自動注射器
US20150250953A1 (en) * 2012-10-12 2015-09-10 Carebay Europe Ltd Medicament Delivery Device
JP2020520755A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 中空プランジャーロッドを備えた自動インジェクタ

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020520755A (ja) * 2017-05-23 2020-07-16 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ 中空プランジャーロッドを備えた自動インジェクタ

Also Published As

Publication number Publication date
RU2019141956A (ru) 2021-06-23
RU2019141956A3 (enExample) 2021-09-03
AU2018272794A1 (en) 2019-12-12
BR112019024354A2 (pt) 2020-06-09
WO2018215270A9 (en) 2020-01-30
CN110913927A (zh) 2020-03-24
US20200108211A1 (en) 2020-04-09
WO2018215270A2 (en) 2018-11-29
WO2018215270A3 (en) 2019-01-17
CA3064671A1 (en) 2018-11-29
EP3630233A2 (en) 2020-04-08

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