JP2020519669A - ホモタウリンおよびその塩の製剤 - Google Patents

ホモタウリンおよびその塩の製剤 Download PDF

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Publication number
JP2020519669A
JP2020519669A JP2019563191A JP2019563191A JP2020519669A JP 2020519669 A JP2020519669 A JP 2020519669A JP 2019563191 A JP2019563191 A JP 2019563191A JP 2019563191 A JP2019563191 A JP 2019563191A JP 2020519669 A JP2020519669 A JP 2020519669A
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pellet
hpmc
less
release
ethyl cellulose
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JP2019563191A
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English (en)
Japanese (ja)
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JP2020519669A5 (https=
Inventor
ジョーンズ，スティーブン
ペイエ，ケネス
ドニパーシ，バドリーナート
Original Assignee
コンフルーエンス ファーマシューティカルズ，エルエルシー
コンフルーエンス ファーマシューティカルズ，エルエルシー
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Application filed by コンフルーエンス ファーマシューティカルズ，エルエルシー, コンフルーエンス ファーマシューティカルズ，エルエルシー filed Critical コンフルーエンス ファーマシューティカルズ，エルエルシー
Publication of JP2020519669A publication Critical patent/JP2020519669A/ja
Publication of JP2020519669A5 publication Critical patent/JP2020519669A5/ja
Priority to JP2023073242A priority Critical patent/JP7499539B2/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019563191A 2017-05-17 2018-05-17 ホモタウリンおよびその塩の製剤 Pending JP2020519669A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023073242A JP7499539B2 (ja) 2017-05-17 2023-04-27 ホモタウリンおよびその塩の製剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762507532P 2017-05-17 2017-05-17
US62/507,532 2017-05-17
US201862660690P 2018-04-20 2018-04-20
US62/660,690 2018-04-20
PCT/US2018/033205 WO2018213589A1 (en) 2017-05-17 2018-05-17 Formulations of homotaurines and salts thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023073242A Division JP7499539B2 (ja) 2017-05-17 2023-04-27 ホモタウリンおよびその塩の製剤

Publications (2)

Publication Number Publication Date
JP2020519669A true JP2020519669A (ja) 2020-07-02
JP2020519669A5 JP2020519669A5 (https=) 2021-07-26

Family

ID=64274653

Family Applications (2)

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JP2019563191A Pending JP2020519669A (ja) 2017-05-17 2018-05-17 ホモタウリンおよびその塩の製剤
JP2023073242A Active JP7499539B2 (ja) 2017-05-17 2023-04-27 ホモタウリンおよびその塩の製剤

Family Applications After (1)

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JP2023073242A Active JP7499539B2 (ja) 2017-05-17 2023-04-27 ホモタウリンおよびその塩の製剤

Country Status (8)

Country Link
US (1) US12042566B2 (https=)
EP (1) EP3624788A4 (https=)
JP (2) JP2020519669A (https=)
KR (1) KR20200005576A (https=)
AU (2) AU2018269557B2 (https=)
IL (1) IL270654B2 (https=)
WO (1) WO2018213589A1 (https=)
ZA (1) ZA201908264B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL270654B2 (en) 2017-05-17 2024-07-01 Confluence Pharmaceuticals Llc Formulations of homotaurines and salts thereof
WO2025163673A1 (en) * 2024-01-29 2025-08-07 Micro Labs Limited Dose-dumping resistant tablets of acamprosate calcium

Citations (7)

* Cited by examiner, † Cited by third party
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JPH04224517A (ja) * 1990-04-17 1992-08-13 Giuliani Spa 標的制御釈放薬剤
JP2001199878A (ja) * 1999-09-13 2001-07-24 Lab Del Dr Esteve Sa 酸に不安定ベンズイミダゾールを含有する修飾された放出特性の経口用固形製剤
JP2012254993A (ja) * 2004-05-11 2012-12-27 Bayer Pharma AG バルデナフィルを含有する制御放出製剤
JP2014508812A (ja) * 2011-03-23 2014-04-10 アイアンショア ファーマシューティカルズ アンド ディベロップメント， インコーポレイテッド 注意欠陥障害の処置のための方法および組成物
JP2015131864A (ja) * 1998-10-01 2015-07-23 エラン ファーマ インターナショナル，リミティド 徐放性ナノ粒子組成物
JP2015528504A (ja) * 2012-09-12 2015-09-28 モノソル アールエックス リミテッド ライアビリティ カンパニー 抗疼痛及び抗嘔気及び／又は抗嘔吐組み合わせ組成物
WO2016179252A1 (en) * 2015-05-04 2016-11-10 Confluence Pharmaceuticals, Llc Sprinkle formulations of acamprosate

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JPH01280192A (ja) 1988-10-25 1989-11-10 Nichibei Co Ltd ブラインド内装サッシ
PE57198A1 (es) 1996-03-25 1998-10-10 American Home Prod Formula de liberacion prolongada
US6514530B2 (en) * 1997-09-09 2003-02-04 Alza Corporation Dosage form comprising means for changing drug delivery shape
FR2775188B1 (fr) 1998-02-23 2001-03-09 Lipha Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
EP1073432B1 (en) 1998-04-14 2007-08-15 The General Hospital Corporation Use of d-serine or d-alanine for treating schizophrenia
US20050142191A1 (en) 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
US20050042277A1 (en) 2003-07-17 2005-02-24 Irukulla Srinivas Pharmaceutical compositions having a swellable coating
CA2504471A1 (en) * 2004-06-18 2005-12-18 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
DE102007009243A1 (de) 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets
JP2010532331A (ja) 2007-07-05 2010-10-07 アンセルム（アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル） 抗痙攣医薬組成物
HRP20150120T1 (hr) 2009-02-12 2015-05-08 Indiana University Research And Technology Corporation Materijal i metode za lijeäśenje poremeä†aja u razvoju ukljuäśujuä†i komorbidni i idiopatski autizam
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US9195775B2 (en) 2009-06-26 2015-11-24 Iii Holdings 2, Llc System and method for managing and/or rendering internet multimedia content in a network
US20110142889A1 (en) 2009-12-16 2011-06-16 Nod Pharmaceuticals, Inc. Compositions and methods for oral drug delivery
US9000046B2 (en) * 2010-09-28 2015-04-07 Depomed, Inc. Gastric retentive dosage forms for extended release of acamprosate into the upper gastrointestinal tract
KR101937782B1 (ko) * 2011-03-01 2019-01-11 파넥스트 바클로펜 및 아캄프로세이트에 기초한 신경 장애의 치료
JP5893135B2 (ja) 2011-06-28 2016-03-23 ビボゾーン インコーポレイテッド 多重ターゲッティングの相乗効果を誘発する有効物質の組合せ及びその用途
US20130143867A1 (en) * 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
CA2879113C (en) 2012-07-22 2021-11-16 Indiana University Research And Technology Corporation Modulation sapp, sapp alpha and bdnf levels in individuals diagnosed with fxs and asd
WO2014197744A1 (en) 2013-06-05 2014-12-11 Synchroneuron, Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
MX2016010409A (es) * 2014-02-11 2016-11-30 Pharnext Combinacion de baclofeno, acamprosato y trigliceridos de cadena media para el tratamiento de trastornos neurologicos.
WO2017024129A1 (en) 2015-08-04 2017-02-09 Confluence Pharmaceuticals, Llc Combination therapy using acamprosate and d-cycloserine
JP6066009B1 (ja) 2016-06-16 2017-01-25 富士電機株式会社 ガス絶縁開閉装置用操作器及びそれを用いたガス絶縁開閉装置
IL270654B2 (en) 2017-05-17 2024-07-01 Confluence Pharmaceuticals Llc Formulations of homotaurines and salts thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04224517A (ja) * 1990-04-17 1992-08-13 Giuliani Spa 標的制御釈放薬剤
JP2015131864A (ja) * 1998-10-01 2015-07-23 エラン ファーマ インターナショナル，リミティド 徐放性ナノ粒子組成物
JP2001199878A (ja) * 1999-09-13 2001-07-24 Lab Del Dr Esteve Sa 酸に不安定ベンズイミダゾールを含有する修飾された放出特性の経口用固形製剤
JP2012254993A (ja) * 2004-05-11 2012-12-27 Bayer Pharma AG バルデナフィルを含有する制御放出製剤
JP2014508812A (ja) * 2011-03-23 2014-04-10 アイアンショア ファーマシューティカルズ アンド ディベロップメント， インコーポレイテッド 注意欠陥障害の処置のための方法および組成物
JP2015528504A (ja) * 2012-09-12 2015-09-28 モノソル アールエックス リミテッド ライアビリティ カンパニー 抗疼痛及び抗嘔気及び／又は抗嘔吐組み合わせ組成物
WO2016179252A1 (en) * 2015-05-04 2016-11-10 Confluence Pharmaceuticals, Llc Sprinkle formulations of acamprosate

Also Published As

Publication number Publication date
AU2018269557B2 (en) 2021-06-03
CA3062834A1 (en) 2018-11-22
KR20200005576A (ko) 2020-01-15
ZA201908264B (en) 2022-03-30
US20200163895A1 (en) 2020-05-28
IL270654B1 (en) 2024-03-01
WO2018213589A1 (en) 2018-11-22
EP3624788A4 (en) 2021-03-03
US12042566B2 (en) 2024-07-23
JP7499539B2 (ja) 2024-06-14
AU2021225172B2 (en) 2023-04-06
AU2018269557A1 (en) 2019-11-28
IL270654A (en) 2020-01-30
AU2021225172A1 (en) 2021-09-30
EP3624788A1 (en) 2020-03-25
JP2023099100A (ja) 2023-07-11
IL270654B2 (en) 2024-07-01

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