JP2020518083A5 - - Google Patents
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- JP2020518083A5 JP2020518083A5 JP2020502531A JP2020502531A JP2020518083A5 JP 2020518083 A5 JP2020518083 A5 JP 2020518083A5 JP 2020502531 A JP2020502531 A JP 2020502531A JP 2020502531 A JP2020502531 A JP 2020502531A JP 2020518083 A5 JP2020518083 A5 JP 2020518083A5
- Authority
- JP
- Japan
- Prior art keywords
- epitope
- factors
- score
- mutation
- factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762479320P | 2017-03-31 | 2017-03-31 | |
| US62/479,320 | 2017-03-31 | ||
| PCT/US2018/025597 WO2018183980A2 (en) | 2017-03-31 | 2018-03-31 | Ranking system for immunogenic cancer-specific epitopes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020518083A JP2020518083A (ja) | 2020-06-18 |
| JP2020518083A5 true JP2020518083A5 (https=) | 2020-07-30 |
| JP7155470B2 JP7155470B2 (ja) | 2022-10-19 |
Family
ID=63676910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502531A Active JP7155470B2 (ja) | 2017-03-31 | 2018-03-31 | 免疫原性がん特異的エピトープのためのランク付けシステム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11485784B2 (https=) |
| EP (1) | EP3600340A4 (https=) |
| JP (1) | JP7155470B2 (https=) |
| CN (1) | CN110799196B (https=) |
| SG (1) | SG11201907738UA (https=) |
| TW (1) | TWI672503B (https=) |
| WO (1) | WO2018183980A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2729116C2 (ru) * | 2015-12-16 | 2020-08-04 | Гритстоун Онколоджи, Инк. | Идентификация, производство и применение неоантигенов |
| KR102841050B1 (ko) * | 2017-04-19 | 2025-08-01 | 그릿스톤 바이오, 인코포레이티드 | 신생항원 동정, 제조, 및 용도 |
| CA3083097A1 (en) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Reducing junction epitope presentation for neoantigens |
| CA3115017C (en) * | 2018-11-21 | 2023-10-31 | Nec Corporation | Method and system of targeting epitopes for neoantigen-based immunotherapy |
| AU2019404547B2 (en) * | 2018-12-21 | 2025-01-30 | Biontech Us Inc. | Method and systems for prediction of HLA class II-specific epitopes and characterization of CD4+ T cells |
| WO2020174077A1 (en) | 2019-02-28 | 2020-09-03 | Universiteit Antwerpen | Method for determining responsiveness to an epitope |
| US20220208306A1 (en) * | 2019-04-30 | 2022-06-30 | Memorial Sloan Kettering Cancer Center | System and methods for identification of non-immunogenic epitopes and determining efficacy of epitopes in therapeutic regimens |
| CN115917654A (zh) * | 2020-04-21 | 2023-04-04 | 瑞泽恩制药公司 | 用于分析受体相互作用的方法和系统 |
| JP2024508677A (ja) * | 2021-02-05 | 2024-02-28 | アマゾン テクノロジーズ インコーポレイテッド | 個別化がんワクチン用ネオアンチゲンのランク付け |
| US12518851B2 (en) * | 2021-09-07 | 2026-01-06 | Nec Corporation | Binding peptide generation for MHC class I proteins with deep reinforcement learning for immunotherapy decision making |
| CN118302816A (zh) * | 2021-09-28 | 2024-07-05 | 行动基因(智财)有限公司 | 甲基化生物标记选择装置及方法 |
| WO2025217519A1 (en) * | 2024-04-12 | 2025-10-16 | Foundation Medicine, Inc. | Clonal neoantigen burden as a biomarker of immunotherapy response |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005301523A (ja) * | 2004-04-08 | 2005-10-27 | Celestar Lexico-Sciences Inc | ワクチン候補部分配列予測装置、ワクチン候補部分配列予測方法、ｍｈｃ結合部分配列予測装置、ｍｈｃ結合部分配列予測方法、プログラムおよび記録媒体 |
| WO2013040142A2 (en) | 2011-09-16 | 2013-03-21 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
| EP3769782A1 (en) | 2013-01-15 | 2021-01-27 | Memorial Sloan Kettering Cancer Center | Immunogenic wt-1 peptides and methods of use thereof |
| CN118750591A (zh) * | 2013-04-07 | 2024-10-11 | 博德研究所 | 用于个性化瘤形成疫苗的组合物和方法 |
| EP3194970B1 (en) * | 2014-09-10 | 2021-07-28 | F. Hoffmann-La Roche AG | Immunogenic mutant peptide screening platform |
| WO2016128060A1 (en) * | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| CA2988388C (en) * | 2015-04-23 | 2022-11-22 | Nantomics, Llc | Cancer neoepitopes |
| CN107750278B (zh) | 2015-04-27 | 2023-10-03 | 癌症研究技术有限公司 | 治疗癌症的方法 |
| EP3323070B1 (en) | 2015-07-14 | 2024-05-08 | Personal Genome Diagnostics Inc. | Neoantigen analysis |
| GB201516047D0 (en) * | 2015-09-10 | 2015-10-28 | Cancer Rec Tech Ltd | Method |
| CN107704727B (zh) * | 2017-11-03 | 2020-01-31 | 杭州风起智能科技有限公司 | 基于肿瘤新抗原特征值的新抗原活性预测和排序方法 |
-
2018
- 2018-03-31 JP JP2020502531A patent/JP7155470B2/ja active Active
- 2018-03-31 CN CN201880019637.1A patent/CN110799196B/zh active Active
- 2018-03-31 TW TW107111453A patent/TWI672503B/zh active
- 2018-03-31 EP EP18776882.5A patent/EP3600340A4/en active Pending
- 2018-03-31 US US16/497,442 patent/US11485784B2/en active Active
- 2018-03-31 WO PCT/US2018/025597 patent/WO2018183980A2/en not_active Ceased
- 2018-03-31 SG SG11201907738UA patent/SG11201907738UA/en unknown
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