JP2020517645A5 - - Google Patents
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- Publication number
- JP2020517645A5 JP2020517645A5 JP2019556913A JP2019556913A JP2020517645A5 JP 2020517645 A5 JP2020517645 A5 JP 2020517645A5 JP 2019556913 A JP2019556913 A JP 2019556913A JP 2019556913 A JP2019556913 A JP 2019556913A JP 2020517645 A5 JP2020517645 A5 JP 2020517645A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- oligonucleotide
- composition according
- bond
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762487425P | 2017-04-19 | 2017-04-19 | |
| US62/487,425 | 2017-04-19 | ||
| PCT/US2018/028308 WO2018195281A1 (en) | 2017-04-19 | 2018-04-19 | P-ethoxy nucleic acids for igf-1r inhibition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020517645A JP2020517645A (ja) | 2020-06-18 |
| JP2020517645A5 true JP2020517645A5 (https=) | 2021-05-27 |
Family
ID=63856055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019556913A Pending JP2020517645A (ja) | 2017-04-19 | 2018-04-19 | Ｉｇｆ−１ｒ阻害のためのｐ−エトキシ核酸 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20200038429A1 (https=) |
| EP (1) | EP3628003A4 (https=) |
| JP (1) | JP2020517645A (https=) |
| KR (1) | KR20200021453A (https=) |
| CN (1) | CN111447922A (https=) |
| AU (1) | AU2018254485B2 (https=) |
| CA (1) | CA3060090A1 (https=) |
| MX (1) | MX2019012493A (https=) |
| WO (1) | WO2018195281A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016164916A1 (en) | 2015-04-10 | 2016-10-13 | Thomas Jefferson University | Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory m2 monocytes |
| CN108291227A (zh) | 2015-10-14 | 2018-07-17 | 拜奥-帕斯控股股份有限公司 | 用于脂质体制剂的对乙氧基核酸 |
| AU2017325971A1 (en) | 2016-09-16 | 2019-04-11 | Bio-Path Holdings, Inc. | Combination therapy with liposomal antisense oligonucleotides |
| EA201992485A1 (ru) | 2017-04-19 | 2020-02-17 | Байо-Пат Холдингз, Инк. | Р-этокси нуклеиновые кислоты для ингибирования stat3 |
| EA201992490A1 (ru) | 2017-04-19 | 2020-03-03 | Байо-Пат Холдингз, Инк. | Р-этокси нуклеиновые кислоты для ингибирования bcl2 |
| EP3873497A4 (en) * | 2018-11-02 | 2022-08-03 | Thomas Jefferson University | METHODS AND COMPOSITIONS FOR THE TREATMENT OF BREAST CANCER USING ANTISENSE NUCLEIC ACIDS |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6340674B1 (en) | 1993-03-26 | 2002-01-22 | Thomas Jefferson University | Method of inhibiting the proliferation and causing the differentiation of cells with IGF-1 receptor antisense oligonucleotides |
| US6015886A (en) * | 1993-05-24 | 2000-01-18 | Chemgenes Corporation | Oligonucleotide phosphate esters |
| US5855911A (en) * | 1995-08-29 | 1999-01-05 | Board Of Regents, The University Of Texas System | Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides |
| US7704962B1 (en) * | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
| US20030180789A1 (en) * | 1998-12-30 | 2003-09-25 | Dale Roderic M.K. | Arrays with modified oligonucleotide and polynucleotide compositions |
| AU2003207708A1 (en) * | 2002-02-20 | 2003-09-09 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of map kinase genes |
| US9150605B2 (en) * | 2002-11-05 | 2015-10-06 | Isis Pharmaceuticals, Inc. | Compositions comprising alternating 2′-modified nucleosides for use in gene modulation |
| JP6637957B2 (ja) | 2014-07-17 | 2020-01-29 | シグニファイ ホールディング ビー ヴィＳｉｇｎｉｆｙ Ｈｏｌｄｉｎｇ Ｂ．Ｖ． | 栽培用照明装置 |
| WO2016164916A1 (en) * | 2015-04-10 | 2016-10-13 | Thomas Jefferson University | Methods and compositions for treating cancers and enhancing therapeutic immunity by selectively reducing immunomodulatory m2 monocytes |
| CN108291227A (zh) * | 2015-10-14 | 2018-07-17 | 拜奥-帕斯控股股份有限公司 | 用于脂质体制剂的对乙氧基核酸 |
-
2018
- 2018-04-19 CA CA3060090A patent/CA3060090A1/en active Pending
- 2018-04-19 EP EP18788289.9A patent/EP3628003A4/en not_active Withdrawn
- 2018-04-19 JP JP2019556913A patent/JP2020517645A/ja active Pending
- 2018-04-19 CN CN201880036079.XA patent/CN111447922A/zh active Pending
- 2018-04-19 AU AU2018254485A patent/AU2018254485B2/en active Active
- 2018-04-19 MX MX2019012493A patent/MX2019012493A/es unknown
- 2018-04-19 KR KR1020197034170A patent/KR20200021453A/ko not_active Ceased
- 2018-04-19 WO PCT/US2018/028308 patent/WO2018195281A1/en not_active Ceased
- 2018-04-19 US US16/606,377 patent/US20200038429A1/en not_active Abandoned
-
2021
- 2021-11-18 US US17/530,051 patent/US12472199B2/en active Active
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