|
US6143749A
(en)
|
1995-06-07 |
2000-11-07 |
Abbott Laboratories |
Heterocyclic substituted cyclopentane compounds
|
|
JP2005527502A
(ja)
|
2002-02-19 |
2005-09-15 |
シーブイ・セラピューティクス・インコーポレイテッド |
Ａ１アデノシン受容体の部分的および全アゴニスト
|
|
US20040043959A1
(en)
|
2002-03-04 |
2004-03-04 |
Bloom Laura A. |
Combination therapies for treating methylthioadenosine phosphorylase deficient cells
|
|
US20040138238A1
(en)
|
2002-08-08 |
2004-07-15 |
Dhanoa Dale S. |
Substituted aminopyrimidine compounds as neurokinin antagonists
|
|
JP4660199B2
(ja)
|
2002-12-23 |
2011-03-30 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
置換１−ピペリジン−４−イル−４−アゼチジン−３−イル−ピペラジン誘導体およびそれらのニューロキニン拮抗薬としての使用
|
|
US7612078B2
(en)
|
2003-03-31 |
2009-11-03 |
Epix Delaware, Inc. |
Piperidinylamino-thieno[2,3-D] pyrimidine compounds
|
|
WO2005110410A2
(en)
|
2004-05-14 |
2005-11-24 |
Abbott Laboratories |
Kinase inhibitors as therapeutic agents
|
|
EP1856128A4
(en)
|
2005-01-19 |
2009-12-23 |
Merck & Co Inc |
INHIBITORS OF MITOTIC KINESINE
|
|
GB0713602D0
(en)
|
2007-07-12 |
2007-08-22 |
Syngenta Participations Ag |
Chemical compounds
|
|
TWI389913B
(zh)
|
2008-09-08 |
2013-03-21 |
Lg Life Sciences Ltd |
并合雜環化合物
|
|
WO2010041366A1
(ja)
|
2008-10-06 |
2010-04-15 |
日本電気株式会社 |
無線通信装置、無線通信システム、無線通信装置の制御方法、及び記録媒体
|
|
JP2011026305A
(ja)
|
2009-06-24 |
2011-02-10 |
Daiichi Sankyo Co Ltd |
イミダゾールカルボニル化合物を含有する医薬組成物
|
|
CN102984941B
(zh)
*
|
2009-09-04 |
2016-08-17 |
密执安大学评议会 |
用于治疗白血病的组合物和方法
|
|
EP2646455A4
(en)
|
2010-12-03 |
2014-04-02 |
Epizyme Inc |
Modulators of histone methyltransferase, and methods of use thereof
|
|
US9145438B2
(en)
|
2010-12-03 |
2015-09-29 |
Epizyme, Inc. |
7-deazapurine modulators of histone methyltransferase, and methods of use thereof
|
|
CN103228195B
(zh)
|
2011-08-01 |
2016-01-20 |
奥林巴斯株式会社 |
插入部形状估计装置
|
|
WO2014035140A2
(en)
|
2012-08-30 |
2014-03-06 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating histone methyltransferase activity
|
|
CN103664991B
(zh)
|
2012-09-19 |
2016-12-28 |
中国科学院福建物质结构研究所 |
噻吩[2,3‑d]嘧啶衍生物、其制备方法及其用途
|
|
DK2935222T3
(en)
|
2012-12-21 |
2019-01-07 |
Epizyme Inc |
PRMT5 INHIBITORS AND APPLICATIONS THEREOF
|
|
CA2894126A1
(en)
|
2012-12-21 |
2014-06-26 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
US9745291B2
(en)
|
2012-12-21 |
2017-08-29 |
Epizyme, Inc. |
PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
|
|
WO2014164543A1
(en)
*
|
2013-03-13 |
2014-10-09 |
The Regents Of The University Of Michigan |
Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof
|
|
US20170119769A1
(en)
*
|
2014-06-10 |
2017-05-04 |
The Trustees Of The University Of Pennsylvania |
Scaffolds for inhibitors of menin-mll interactions
|
|
US20170198006A1
(en)
|
2014-06-25 |
2017-07-13 |
Epizyme, Inc. |
Prmt5 inhibitors and uses thereof
|
|
USRE49687E1
(en)
|
2014-09-09 |
2023-10-10 |
The Regents Of The University Of Michigan |
Thienopyrimidine and thienopyridine compounds and methods of use thereof
|
|
WO2016081732A1
(en)
*
|
2014-11-19 |
2016-05-26 |
Memorial Sloan-Kettering Cancer Center |
Thienopyrimidines and uses thereof
|
|
CN105732636B
(zh)
|
2014-12-30 |
2020-04-21 |
广东东阳光药业有限公司 |
杂芳化合物及其在药物中的应用
|
|
MX2017010844A
(es)
|
2015-02-24 |
2017-12-07 |
Pfizer |
Derivados de nucleosidos sustituidos utiles como agentes anticancerosos.
|
|
HK1246593A1
(zh)
|
2015-06-04 |
2018-09-14 |
Kura Oncology, Inc. |
用於抑制menin蛋白与mll蛋白的相互作用的方法及组合物
|
|
TWI703150B
(zh)
|
2015-06-04 |
2020-09-01 |
美商庫拉腫瘤技術股份有限公司 |
用於抑制ｍｅｎｉｎ及ｍｌｌ蛋白之交互作用的方法及組合物
|
|
TWI870767B
(zh)
|
2015-08-26 |
2025-01-21 |
比利時商健生藥品公司 |
使用作為prmt5抑制劑之新穎經6-6雙環芳香環取代之核苷類似物
|
|
AU2016378579A1
(en)
|
2015-12-22 |
2018-06-14 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of the menin-MLL interaction
|
|
PH12018501955B1
(en)
|
2016-03-16 |
2024-01-24 |
Kura Oncology Inc |
Bridged bicyclic inhibitors of menin-mll and methods of use
|
|
PL3429591T3
(pl)
|
2016-03-16 |
2023-07-17 |
Kura Oncology, Inc. |
Podstawione pochodne tieno[2,3-d]pirymidyny jako inhibitory meniny-mll i metody ich zastosowania
|
|
JP6991585B2
(ja)
|
2016-05-02 |
2022-01-12 |
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン |
メニン阻害剤としてのピペリジン
|
|
WO2017207387A1
(en)
|
2016-05-31 |
2017-12-07 |
Bayer Pharma Aktiengesellschaft |
Spiro condensed azetidine derivatives as inhibitors of the menin-mml1 interaction
|
|
WO2017214367A1
(en)
|
2016-06-10 |
2017-12-14 |
Vitae Pharmaceuticals, Inc. |
Inhibitors of the menin-mll interaction
|
|
WO2018024602A1
(en)
|
2016-08-04 |
2018-02-08 |
Bayer Aktiengesellschaft |
2,7-diazaspiro[4.4]nonanes
|
|
WO2018047598A1
(ja)
|
2016-09-06 |
2018-03-15 |
株式会社スリーボンド |
熱硬化型導電性接着剤
|
|
CA3033239A1
(en)
|
2016-09-14 |
2018-03-22 |
Janssen Pharmaceutica Nv |
Spiro bicyclic inhibitors of menin-mll interaction
|
|
CA3033020A1
(en)
|
2016-09-14 |
2018-03-22 |
Janssen Pharmaceutica Nv |
Fused bicyclic inhibitors of menin-mll interaction
|
|
EP3512857B1
(en)
|
2016-09-14 |
2021-02-24 |
Janssen Pharmaceutica NV |
Spiro bicyclic inhibitors of menin-mll interaction
|
|
AU2017326006B2
(en)
|
2016-09-16 |
2021-10-28 |
Vitae Pharmaceuticals, LLC. |
Inhibitors of the menin-MLL interaction
|
|
WO2018109088A1
(en)
|
2016-12-15 |
2018-06-21 |
Janssen Pharmaceutica Nv |
Azepane inhibitors of menin-mll interaction
|
|
WO2018175746A1
(en)
|
2017-03-24 |
2018-09-27 |
Kura Oncology, Inc. |
Methods for treating hematological malignancies and ewing's sarcoma
|