JP2020511933A - 癌検出のための方法 - Google Patents

癌検出のための方法 Download PDF

Info

Publication number
JP2020511933A
JP2020511933A JP2019527223A JP2019527223A JP2020511933A JP 2020511933 A JP2020511933 A JP 2020511933A JP 2019527223 A JP2019527223 A JP 2019527223A JP 2019527223 A JP2019527223 A JP 2019527223A JP 2020511933 A JP2020511933 A JP 2020511933A
Authority
JP
Japan
Prior art keywords
biomarker
subject
cancer
sample
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019527223A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020511933A5 (enExample
Inventor
フェルドマン,ロバート
マタニ,メラニー
Original Assignee
プライム ゲノミクス,インク.
プライム ゲノミクス,インク.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by プライム ゲノミクス,インク., プライム ゲノミクス,インク. filed Critical プライム ゲノミクス,インク.
Publication of JP2020511933A publication Critical patent/JP2020511933A/ja
Publication of JP2020511933A5 publication Critical patent/JP2020511933A5/ja
Priority to JP2022116618A priority Critical patent/JP2022163076A/ja
Pending legal-status Critical Current

Links

Classifications

    • G01N33/57515
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57415Specifically defined cancers of breast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2019527223A 2016-11-22 2017-11-22 癌検出のための方法 Pending JP2020511933A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022116618A JP2022163076A (ja) 2016-11-22 2022-07-21 癌検出のための方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662425549P 2016-11-22 2016-11-22
US62/425,549 2016-11-22
PCT/US2017/063157 WO2018098379A1 (en) 2016-11-22 2017-11-22 Methods for cancer detection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022116618A Division JP2022163076A (ja) 2016-11-22 2022-07-21 癌検出のための方法

Publications (2)

Publication Number Publication Date
JP2020511933A true JP2020511933A (ja) 2020-04-23
JP2020511933A5 JP2020511933A5 (enExample) 2021-01-14

Family

ID=62195635

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019527223A Pending JP2020511933A (ja) 2016-11-22 2017-11-22 癌検出のための方法
JP2022116618A Pending JP2022163076A (ja) 2016-11-22 2022-07-21 癌検出のための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022116618A Pending JP2022163076A (ja) 2016-11-22 2022-07-21 癌検出のための方法

Country Status (8)

Country Link
US (1) US20200081008A1 (enExample)
EP (1) EP3544605A4 (enExample)
JP (2) JP2020511933A (enExample)
CN (1) CN110198711A (enExample)
CA (1) CA3044257A1 (enExample)
MA (1) MA46927A (enExample)
MX (1) MX2019006005A (enExample)
WO (1) WO2018098379A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022163076A (ja) * 2016-11-22 2022-10-25 プライム ゲノミクス,インク. 癌検出のための方法
JP2023534094A (ja) * 2020-06-16 2023-08-08 グレイル エルエルシー 無細胞rnaの分析方法
JP2023541718A (ja) * 2020-09-01 2023-10-03 オンコデア・コーポレーション 病気の早期検出および監視のための予測診断検査

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108830045B (zh) * 2018-06-29 2021-04-20 深圳先进技术研究院 一种基于多组学的生物标记物系统筛选方法
KR102211972B1 (ko) * 2018-08-02 2021-02-04 엑소젠 피티이. 엘티디 액체생검 다중 암 유전자 바이오마커를 이용한 유방암 조기진단 및 치료 후 모니터링 방법
WO2020180896A1 (en) * 2019-03-03 2020-09-10 Purdue Research Foundation Systems and methods for identifying subtype, prognosis and monitoring of breast cancer
CN111679076A (zh) * 2020-06-15 2020-09-18 吉林医药学院 一种用于检测cyclinD1和BCL-2抗体的检测试剂盒
CN111979321B (zh) * 2020-08-26 2022-07-12 郑州大学第一附属医院 用于胰腺癌检查的基因标记物
CN115927610B (zh) * 2022-07-19 2024-11-05 武汉艾米森生命科技有限公司 检测foxo6基因中目标区域的甲基化水平的试剂在制备膀胱癌诊断产品中的应用
WO2025005966A1 (en) * 2023-06-29 2025-01-02 Edge Animal Health, Inc. Urine pcr assay and use thereof to diagnose and stage feline chronic kidney disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002538462A (ja) * 1999-03-01 2002-11-12 ユニバーシティー オブ ミシシッピ メディカル センター 乳癌の診断とモニタリングの方法
WO2008035444A1 (en) * 2006-09-22 2008-03-27 Aloka Co., Ltd. Ultrasonic breast diagnostic system
JP2014507160A (ja) * 2011-02-22 2014-03-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス.アー.エール.エル. 循環バイオマーカー

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358683B1 (en) * 1999-06-03 2002-03-19 The Regents Of The University Of California Blood-based assays for breast cancer
GB201000688D0 (en) * 2010-01-15 2010-03-03 Diagenic Asa Product and method
WO2011100472A1 (en) * 2010-02-10 2011-08-18 The Regents Of The University Of California Salivary transcriptomic and proteomic biomarkers for breast cancer detection
CA2803266A1 (en) * 2010-07-08 2012-01-12 Prime Genomics, Inc. System for the quantification of system-wide dynamics in complex networks
KR101335034B1 (ko) * 2011-08-25 2013-12-02 주식회사 바이오인프라 유방암 진단을 위한 엑소좀 내의 ANT2 mRNA의 이용방법
AU2015210886A1 (en) * 2014-01-29 2016-09-01 Caris Mpi, Inc. Molecular profiling of immune modulators
WO2015187727A2 (en) * 2014-06-04 2015-12-10 Atossa Genetics Inc. Molecular mammography
WO2016004387A1 (en) * 2014-07-02 2016-01-07 H. Lee Moffitt Cancer Center And Research Institute, Inc. Gene expression signature for cancer prognosis
CA3044257A1 (en) * 2016-11-22 2018-05-31 Prime Genomics, Inc. Methods for cancer detection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002538462A (ja) * 1999-03-01 2002-11-12 ユニバーシティー オブ ミシシッピ メディカル センター 乳癌の診断とモニタリングの方法
WO2008035444A1 (en) * 2006-09-22 2008-03-27 Aloka Co., Ltd. Ultrasonic breast diagnostic system
JP2014507160A (ja) * 2011-02-22 2014-03-27 カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス.アー.エール.エル. 循環バイオマーカー

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022163076A (ja) * 2016-11-22 2022-10-25 プライム ゲノミクス,インク. 癌検出のための方法
JP2023534094A (ja) * 2020-06-16 2023-08-08 グレイル エルエルシー 無細胞rnaの分析方法
JP2023541718A (ja) * 2020-09-01 2023-10-03 オンコデア・コーポレーション 病気の早期検出および監視のための予測診断検査

Also Published As

Publication number Publication date
MA46927A (fr) 2019-10-02
EP3544605A4 (en) 2020-11-25
WO2018098379A1 (en) 2018-05-31
CN110198711A (zh) 2019-09-03
US20200081008A1 (en) 2020-03-12
MX2019006005A (es) 2019-10-02
CA3044257A1 (en) 2018-05-31
EP3544605A1 (en) 2019-10-02
JP2022163076A (ja) 2022-10-25

Similar Documents

Publication Publication Date Title
JP2022163076A (ja) 癌検出のための方法
US20220325348A1 (en) Biomarker signature method, and apparatus and kits therefor
JP6161607B2 (ja) サンプルにおける異なる異数性の有無を決定する方法
CN105917008B (zh) 用于前列腺癌复发的预后的基因表达面板
JP7334122B2 (ja) 妊娠高血圧腎症に特異的な循環rnaシグネチャー
CN114026646A (zh) 用于评估肿瘤分数的系统和方法
CN110800063A (zh) 使用无细胞dna片段大小检测肿瘤相关变体
US20230178245A1 (en) Immunotherapy Response Signature
US20230368915A1 (en) Metastasis predictor
JP2023515394A (ja) パノミックゲノム出現率スコア
JP2011525106A (ja) 瀰漫性b大細胞型リンパ腫のマーカーおよびその使用方法
TW202305142A (zh) 游離dna甲基化及核酸酶介導之片段化
JP2019527343A (ja) 癌のエキソソーム誘導治療
CN108611410B (zh) N6-甲基腺嘌呤在自身免疫性疾病的用途
JP2024534509A (ja) cfRNAおよびcfTNAの標的NGSシーケンシングのための組成物および方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20191112

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20201119

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20201119

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20210930

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20211006

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220106

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220518

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20221212