JP2020510438A5 - - Google Patents
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- Publication number
- JP2020510438A5 JP2020510438A5 JP2019548921A JP2019548921A JP2020510438A5 JP 2020510438 A5 JP2020510438 A5 JP 2020510438A5 JP 2019548921 A JP2019548921 A JP 2019548921A JP 2019548921 A JP2019548921 A JP 2019548921A JP 2020510438 A5 JP2020510438 A5 JP 2020510438A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- target polypeptide
- cell population
- cell
- mammalian cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 25
- 210000004027 cell Anatomy 0.000 claims 22
- 229920001184 polypeptide Polymers 0.000 claims 16
- 102000004196 processed proteins & peptides Human genes 0.000 claims 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 210000004962 mammalian cell Anatomy 0.000 claims 15
- 230000003248 secreting effect Effects 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 3
- 230000003278 mimic effect Effects 0.000 claims 3
- 108010052285 Membrane Proteins Proteins 0.000 claims 2
- 102000018697 Membrane Proteins Human genes 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 241000283690 Bos taurus Species 0.000 claims 1
- 241000282693 Cercopithecidae Species 0.000 claims 1
- 241000699800 Cricetinae Species 0.000 claims 1
- 108700022150 Designed Ankyrin Repeat Proteins Proteins 0.000 claims 1
- 241000283074 Equus asinus Species 0.000 claims 1
- 241000283073 Equus caballus Species 0.000 claims 1
- 241000282414 Homo sapiens Species 0.000 claims 1
- 102000037982 Immune checkpoint proteins Human genes 0.000 claims 1
- 108091008036 Immune checkpoint proteins Proteins 0.000 claims 1
- 241000699666 Mus <mouse, genus> Species 0.000 claims 1
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 1
- 241001494479 Pecora Species 0.000 claims 1
- 241000700159 Rattus Species 0.000 claims 1
- 102000009661 Repressor Proteins Human genes 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 229940126546 immune checkpoint molecule Drugs 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 108700020534 tetracycline resistance-encoding transposon repressor Proteins 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023159291A JP2024001060A (ja) | 2017-03-15 | 2023-09-23 | 抗体の選択方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1704115.3A GB201704115D0 (en) | 2017-03-15 | 2017-03-15 | Method of selecting for antibodies |
| GB1704115.3 | 2017-03-15 | ||
| PCT/GB2018/050645 WO2018167481A1 (en) | 2017-03-15 | 2018-03-14 | Method of selecting for antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023159291A Division JP2024001060A (ja) | 2017-03-15 | 2023-09-23 | 抗体の選択方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020510438A JP2020510438A (ja) | 2020-04-09 |
| JP2020510438A5 true JP2020510438A5 (https=) | 2021-04-22 |
Family
ID=58605467
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548921A Pending JP2020510438A (ja) | 2017-03-15 | 2018-03-14 | 抗体の選択方法 |
| JP2023159291A Pending JP2024001060A (ja) | 2017-03-15 | 2023-09-23 | 抗体の選択方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023159291A Pending JP2024001060A (ja) | 2017-03-15 | 2023-09-23 | 抗体の選択方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20200072820A1 (https=) |
| EP (1) | EP3596128A1 (https=) |
| JP (2) | JP2020510438A (https=) |
| KR (1) | KR102499955B1 (https=) |
| CN (1) | CN110382548A (https=) |
| AU (1) | AU2018234291A1 (https=) |
| GB (1) | GB201704115D0 (https=) |
| SG (1) | SG11201907925WA (https=) |
| WO (1) | WO2018167481A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110892064A (zh) | 2017-07-25 | 2020-03-17 | 牛津遗传学有限公司 | 腺病毒载体 |
| GB201901571D0 (en) | 2019-02-05 | 2019-03-27 | Oxford Genetics Ltd | Inducible AAV sysyem |
| GB201903233D0 (en) | 2019-03-08 | 2019-04-24 | Oxford Genetics Ltd | Method of selecting for antibodies |
| CN113544509A (zh) * | 2019-03-08 | 2021-10-22 | 牛津遗传学有限公司 | 选择抗体的方法 |
| US20230348891A1 (en) * | 2020-08-21 | 2023-11-02 | Hifibio (Shanghai) Limited | Functional screening using droplet-based microfluidics |
| KR20250017210A (ko) * | 2022-05-03 | 2025-02-04 | 엠브레이스 테라퓨틱스, 인크. | 재조합 항체 생산 방법 및 관련된 세포 시스템 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04234987A (ja) * | 1990-12-28 | 1992-08-24 | Mitsubishi Kasei Corp | Ｄｎａ断片 |
| US6919183B2 (en) * | 2001-01-16 | 2005-07-19 | Regeneron Pharmaceuticals, Inc. | Isolating cells expressing secreted proteins |
| US20140072979A1 (en) * | 2001-01-16 | 2014-03-13 | Regeneron Pharmaceuticals, Inc. | Isolating cells expressing secreted proteins |
| EP1420803A1 (en) * | 2001-08-08 | 2004-05-26 | Board Of Regents, The University Of Texas System | Method for amplifying expression from a cell specific promoter |
| EP2617827A1 (en) * | 2007-03-26 | 2013-07-24 | Celexion, LLC | Method for displaying engineered proteins on a cell surface |
| WO2009103753A1 (en) * | 2008-02-20 | 2009-08-27 | Ablynx Nv | Methods for identifying and/or sorting cells by secreted molecule and kits for performing such methods |
| JP2009268399A (ja) * | 2008-05-07 | 2009-11-19 | Tosoh Corp | 抗体に結合可能な蛋白質発現ミエローマおよびこれを用いる細胞融合方法並びに交雑細胞およびその選別方法 |
| CN102282266A (zh) * | 2008-11-21 | 2011-12-14 | 德根生物科技有限公司 | 高复杂度哺乳动物展示文库及其筛选方法 |
| US9365846B2 (en) * | 2010-12-01 | 2016-06-14 | Merck Sharp & Dohme Corp. | Surface, anchored Fc-bait antibody display system |
| US20150219649A1 (en) * | 2012-08-21 | 2015-08-06 | Medetect Ab | Method for improved cell identification |
| US9487773B2 (en) * | 2013-03-01 | 2016-11-08 | Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa | Cell-based methods for coupling protein interactions and binding molecule selection |
-
2017
- 2017-03-15 GB GBGB1704115.3A patent/GB201704115D0/en not_active Ceased
-
2018
- 2018-03-14 EP EP18714021.5A patent/EP3596128A1/en not_active Withdrawn
- 2018-03-14 KR KR1020197028842A patent/KR102499955B1/ko active Active
- 2018-03-14 AU AU2018234291A patent/AU2018234291A1/en not_active Abandoned
- 2018-03-14 CN CN201880016352.2A patent/CN110382548A/zh active Pending
- 2018-03-14 SG SG11201907925WA patent/SG11201907925WA/en unknown
- 2018-03-14 WO PCT/GB2018/050645 patent/WO2018167481A1/en not_active Ceased
- 2018-03-14 JP JP2019548921A patent/JP2020510438A/ja active Pending
- 2018-03-14 US US16/492,777 patent/US20200072820A1/en not_active Abandoned
-
2023
- 2023-09-23 JP JP2023159291A patent/JP2024001060A/ja active Pending
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