JP2020510415A5 - - Google Patents
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- JP2020510415A5 JP2020510415A5 JP2019543091A JP2019543091A JP2020510415A5 JP 2020510415 A5 JP2020510415 A5 JP 2020510415A5 JP 2019543091 A JP2019543091 A JP 2019543091A JP 2019543091 A JP2019543091 A JP 2019543091A JP 2020510415 A5 JP2020510415 A5 JP 2020510415A5
- Authority
- JP
- Japan
- Prior art keywords
- plate
- sample
- nucleic acid
- target
- closed configuration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000523 sample Substances 0.000 claims description 60
- 108020004707 nucleic acids Proteins 0.000 claims description 34
- 150000007523 nucleic acids Chemical class 0.000 claims description 34
- 102000039446 nucleic acids Human genes 0.000 claims description 34
- 230000003321 amplification Effects 0.000 claims description 33
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 32
- 230000001419 dependent effect Effects 0.000 claims description 16
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims description 9
- 239000002853 nucleic acid probe Substances 0.000 claims description 9
- 238000003556 assay Methods 0.000 claims description 8
- 238000005406 washing Methods 0.000 claims description 8
- 239000012491 analyte Substances 0.000 claims description 6
- 239000012620 biological material Substances 0.000 claims description 6
- 239000003153 chemical reaction reagent Substances 0.000 claims description 6
- 238000004140 cleaning Methods 0.000 claims description 6
- 239000002516 radical scavenger Substances 0.000 claims description 6
- 238000001514 detection method Methods 0.000 claims description 5
- 238000009396 hybridization Methods 0.000 claims description 5
- 238000011010 flushing procedure Methods 0.000 claims description 2
- 238000011534 incubation Methods 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims description 2
- 238000003753 real-time PCR Methods 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 239000007769 metal material Substances 0.000 description 4
- 239000003989 dielectric material Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 125000006850 spacer group Chemical group 0.000 description 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 108091070501 miRNA Proteins 0.000 description 1
- 239000002679 microRNA Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762456598P | 2017-02-08 | 2017-02-08 | |
| US62/456,598 | 2017-02-08 | ||
| US201762457084P | 2017-02-09 | 2017-02-09 | |
| US201762456904P | 2017-02-09 | 2017-02-09 | |
| US201762457075P | 2017-02-09 | 2017-02-09 | |
| US62/457,084 | 2017-02-09 | ||
| US62/457,075 | 2017-02-09 | ||
| US62/456,904 | 2017-02-09 | ||
| US201762459337P | 2017-02-15 | 2017-02-15 | |
| US201762459267P | 2017-02-15 | 2017-02-15 | |
| US201762459303P | 2017-02-15 | 2017-02-15 | |
| US62/459,303 | 2017-02-15 | ||
| US62/459,337 | 2017-02-15 | ||
| US62/459,267 | 2017-02-15 | ||
| US201762460083P | 2017-02-16 | 2017-02-16 | |
| US201762460052P | 2017-02-16 | 2017-02-16 | |
| US62/460,052 | 2017-02-16 | ||
| US62/460,083 | 2017-02-16 | ||
| PCT/US2018/017494 WO2018148463A1 (en) | 2017-02-08 | 2018-02-08 | Nucleic acid hybridization assay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510415A JP2020510415A (ja) | 2020-04-09 |
| JP2020510415A5 true JP2020510415A5 (https=) | 2021-03-25 |
| JP7090093B2 JP7090093B2 (ja) | 2022-06-23 |
Family
ID=63108241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543091A Active JP7090093B2 (ja) | 2017-02-08 | 2018-02-08 | 核酸ハイブリダイゼーションアッセイ |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11408028B2 (https=) |
| JP (1) | JP7090093B2 (https=) |
| CN (2) | CN110785498B (https=) |
| CA (1) | CA3052963A1 (https=) |
| WO (1) | WO2018148463A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106148502B (zh) * | 2014-12-11 | 2020-02-28 | 中国科学院上海生命科学研究院 | 一种直接检测食源致病菌的高通量方法 |
| CN110998325B (zh) * | 2017-02-09 | 2024-08-16 | 上海宜晟生物科技有限公司 | 扩增测定 |
| US11327022B2 (en) * | 2017-02-24 | 2022-05-10 | Dongmao Zhang | Accessories for Raman and luminescence spectral acquisitions |
| CN120801147A (zh) * | 2018-08-16 | 2025-10-17 | 上海宜晟生物科技有限公司 | 体液，特别是血液中的细胞分析 |
| US20220276235A1 (en) * | 2019-07-18 | 2022-09-01 | Essenlix Corporation | Imaging based homogeneous assay |
| CN111617813B (zh) * | 2020-06-05 | 2021-11-30 | 深圳市尚维高科有限公司 | 生物检测芯片及制作方法 |
| CN114292904B (zh) * | 2021-12-25 | 2022-11-01 | 武汉承启医学检验实验室有限公司 | 一种优化ctDNA检测准确率的方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022521A (en) * | 1974-02-19 | 1977-05-10 | Honeywell Inc. | Microscope slide |
| US6358475B1 (en) * | 1998-05-27 | 2002-03-19 | Becton, Dickinson And Company | Device for preparing thin liquid for microscopic analysis |
| JP2003522963A (ja) * | 2000-02-18 | 2003-07-29 | アクララ バイオサイエンシーズ， インコーポレイテッド | 複数部位反応デバイスおよび方法 |
| AU2003282675A1 (en) | 2002-10-02 | 2004-04-23 | New Light Industries, Ltd | Manufacturing method and readout system for biopolymer arrays |
| US8916348B2 (en) * | 2004-05-06 | 2014-12-23 | Clondiag Gmbh | Method and device for the detection of molecular interactions |
| US7429923B2 (en) * | 2004-10-22 | 2008-09-30 | Honeywell International Inc. | Neuronal sensor networks |
| EP1659183A1 (en) | 2004-11-18 | 2006-05-24 | Eppendorf Array Technologies | Real-time quantification of multiple targets on a micro-array |
| WO2008022332A2 (en) * | 2006-08-18 | 2008-02-21 | Board Of Regents, The University Of Texas System | System, method and kit for replicating a dna array |
| US20140154668A1 (en) * | 2010-05-21 | 2014-06-05 | The Trustees Of Princeton University | Structures for Enhancement of Local Electric Field, Light Absorption, Light Radiation, Material Detection and Methods for Making and Using of the Same. |
| EP2960651B1 (en) | 2013-02-22 | 2017-12-20 | Hitachi High-Technologies Corporation | Bioanalysis device and biomolecule analyser |
| CN108780081B (zh) * | 2015-08-10 | 2021-04-09 | Essenlix公司 | 步骤简化、小样品、快速、易使用的生物/化学分析装置和方法 |
| CN110998325B (zh) * | 2017-02-09 | 2024-08-16 | 上海宜晟生物科技有限公司 | 扩增测定 |
| EP3638421A4 (en) * | 2017-06-12 | 2021-04-07 | Essenlix Corporation | HOMOGENOUS ASSAY |
| US11609224B2 (en) * | 2017-10-26 | 2023-03-21 | Essenlix Corporation | Devices and methods for white blood cell analyses |
-
2018
- 2018-02-08 JP JP2019543091A patent/JP7090093B2/ja active Active
- 2018-02-08 CN CN201880019334.XA patent/CN110785498B/zh active Active
- 2018-02-08 CN CN202410546349.9A patent/CN118440814A/zh active Pending
- 2018-02-08 CA CA3052963A patent/CA3052963A1/en active Pending
- 2018-02-08 WO PCT/US2018/017494 patent/WO2018148463A1/en not_active Ceased
- 2018-02-08 US US16/483,833 patent/US11408028B2/en active Active
-
2022
- 2022-03-22 US US17/701,562 patent/US20220213536A1/en not_active Abandoned
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