JP2020505425A - 癌治療 - Google Patents

癌治療 Download PDF

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Publication number
JP2020505425A
JP2020505425A JP2019541398A JP2019541398A JP2020505425A JP 2020505425 A JP2020505425 A JP 2020505425A JP 2019541398 A JP2019541398 A JP 2019541398A JP 2019541398 A JP2019541398 A JP 2019541398A JP 2020505425 A JP2020505425 A JP 2020505425A
Authority
JP
Japan
Prior art keywords
eldafitinib
treatment
serum phosphate
day
specifically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2019541398A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020505425A5 (https=
Inventor
スツイッケンズ，キム
ルイクソ，ジュアン，ホセ ペレス
ルイクソ，ジュアン，ホセ ペレス
ドュ，ポッレ，ピーター，マリー，ゼット．
アヴァドハニ，アンジャリ，ナラヤン．
ロリオット，ヨハン
シエフカー−ラドケ，アーリーン，オー．
Original Assignee
ヤンセン ファーマシューティカ エヌ．ベー．
ヤンセン ファーマシューティカ エヌ．ベー．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61094531&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2020505425(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ヤンセン ファーマシューティカ エヌ．ベー．, ヤンセン ファーマシューティカ エヌ．ベー． filed Critical ヤンセン ファーマシューティカ エヌ．ベー．
Priority claimed from PCT/EP2018/052694 external-priority patent/WO2018141921A1/en
Publication of JP2020505425A publication Critical patent/JP2020505425A/ja
Publication of JP2020505425A5 publication Critical patent/JP2020505425A5/ja
Priority to JP2022189239A priority Critical patent/JP7668777B2/ja
Priority to JP2024196985A priority patent/JP2025024064A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Laminated Bodies (AREA)
JP2019541398A 2017-02-06 2018-02-02 癌治療 Withdrawn JP2020505425A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022189239A JP7668777B2 (ja) 2017-02-06 2022-11-28 癌治療
JP2024196985A JP2025024064A (ja) 2017-02-06 2024-11-11 癌治療

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762455211P 2017-02-06 2017-02-06
US62/455,211 2017-02-06
EP17209098 2017-12-20
EP17209098.7 2017-12-20
PCT/EP2018/052694 WO2018141921A1 (en) 2017-02-06 2018-02-02 Cancer treatment

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022189239A Division JP7668777B2 (ja) 2017-02-06 2022-11-28 癌治療

Publications (2)

Publication Number Publication Date
JP2020505425A true JP2020505425A (ja) 2020-02-20
JP2020505425A5 JP2020505425A5 (https=) 2021-03-18

Family

ID=61094531

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019541398A Withdrawn JP2020505425A (ja) 2017-02-06 2018-02-02 癌治療
JP2022189239A Active JP7668777B2 (ja) 2017-02-06 2022-11-28 癌治療
JP2024196985A Pending JP2025024064A (ja) 2017-02-06 2024-11-11 癌治療

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2022189239A Active JP7668777B2 (ja) 2017-02-06 2022-11-28 癌治療
JP2024196985A Pending JP2025024064A (ja) 2017-02-06 2024-11-11 癌治療

Country Status (26)

Country Link
US (2) US11077106B2 (https=)
EP (2) EP4286005A3 (https=)
JP (3) JP2020505425A (https=)
KR (2) KR20250069693A (https=)
CN (1) CN110198716A (https=)
AU (2) AU2018216969B2 (https=)
BR (1) BR112019016043A2 (https=)
CA (1) CA3049737A1 (https=)
DK (1) DK3576740T3 (https=)
ES (1) ES2953005T3 (https=)
FI (1) FI3576740T3 (https=)
HR (1) HRP20230697T1 (https=)
HU (1) HUE062453T2 (https=)
IL (1) IL268463A (https=)
JO (1) JOP20190190B1 (https=)
LT (1) LT3576740T (https=)
MX (2) MX2019009304A (https=)
NZ (2) NZ755301A (https=)
PH (1) PH12019501885A1 (https=)
PL (1) PL3576740T3 (https=)
RS (1) RS64778B1 (https=)
SG (2) SG10202105110VA (https=)
SI (1) SI3576740T1 (https=)
SM (1) SMT202300233T1 (https=)
TW (1) TWI874925B (https=)
UA (1) UA126336C2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021201201A1 (ja) * 2020-04-03 2021-10-07 インタープロテイン株式会社 新型コロナウイルス感染症（ｃｏｖｉｄ－１９）の予防または治療剤および医薬組成物
JP2022527189A (ja) * 2019-03-29 2022-05-31 ヤンセン ファーマシューティカ エヌ．ベー． 尿路上皮癌の治療のためのｆｇｆｒチロシンキナーゼ阻害剤

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200208224A1 (en) * 2014-09-26 2020-07-02 Janssen Pharmaceutica Nv Use Of FGFR Mutant Gene Panels In Identifying Cancer Patients That Will Be Responsive To Treatment With An FGFR Inhibitor
KR102470456B1 (ko) 2014-09-26 2022-11-23 얀센 파마슈티카 엔.브이. Fgfr 억제제를 사용한 치료에 반응할 암 환자를 확인하는 데 있어서 fgfr 돌연변이 유전자 패널의 사용
HUE062453T2 (hu) * 2017-02-06 2023-11-28 Janssen Pharmaceutica Nv Rákbetegség kezelése
EP3923942A1 (en) * 2019-02-12 2021-12-22 Janssen Pharmaceutica NV Cancer treatment
MA55486A (fr) * 2019-03-29 2022-02-09 Janssen Pharmaceutica Nv Inhibiteurs de la tyrosine kinase fgfr pour le traitement du carcinome urothélial
CN115103678A (zh) * 2020-02-12 2022-09-23 詹森药业有限公司 用于治疗高风险非肌层浸润性膀胱癌的fgfr酪氨酸激酶抑制剂
EP4719420A1 (en) * 2023-05-24 2026-04-08 Janssen Pharmaceutica NV Treatment of locally advanced or metastatic urothelial carcinoma with erdafinitib

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016161239A1 (en) * 2015-04-03 2016-10-06 Astex Therapeutics Limited Fgfr/pd-1 combination therapy for the treatment of cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI719960B (zh) * 2015-02-10 2021-03-01 英商阿斯迪克治療公司 新穎組成物
HUE062453T2 (hu) * 2017-02-06 2023-11-28 Janssen Pharmaceutica Nv Rákbetegség kezelése

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016161239A1 (en) * 2015-04-03 2016-10-06 Astex Therapeutics Limited Fgfr/pd-1 combination therapy for the treatment of cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ARCHIVE HISTORY FOR NCT02365597, JPN6021047115, 21 January 2017 (2017-01-21), ISSN: 0004834168 *
J. CLIN. ONCOL., vol. 33, no. 30, JPN6021047113, 2015, pages 3401 - 3408, ISSN: 0004834170 *
J. GASTROINTEST. ONCOL., vol. 7, no. 5, JPN6021047114, 2016, pages 789 - 796, ISSN: 0004834169 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022527189A (ja) * 2019-03-29 2022-05-31 ヤンセン ファーマシューティカ エヌ．ベー． 尿路上皮癌の治療のためのｆｇｆｒチロシンキナーゼ阻害剤
JP7747521B2 (ja) 2019-03-29 2025-10-01 ヤンセン ファーマシューティカ エヌ．ベー． 尿路上皮癌の治療のためのｆｇｆｒチロシンキナーゼ阻害剤
WO2021201201A1 (ja) * 2020-04-03 2021-10-07 インタープロテイン株式会社 新型コロナウイルス感染症（ｃｏｖｉｄ－１９）の予防または治療剤および医薬組成物

Also Published As

Publication number Publication date
DK3576740T3 (da) 2023-07-24
TW202402290A (zh) 2024-01-16
JP2025024064A (ja) 2025-02-19
AU2024201871B2 (en) 2026-02-26
US20200022976A1 (en) 2020-01-23
NZ755301A (en) 2025-12-19
HRP20230697T1 (hr) 2023-10-13
SG11201907199QA (en) 2019-09-27
JP2023022190A (ja) 2023-02-14
ES2953005T3 (es) 2023-11-07
LT3576740T (lt) 2023-08-10
IL268463A (en) 2019-09-26
KR20250069693A (ko) 2025-05-19
EP4286005A3 (en) 2024-03-06
EP4286005A2 (en) 2023-12-06
MX2019009304A (es) 2019-09-19
JP7668777B2 (ja) 2025-04-25
SMT202300233T1 (it) 2023-09-06
US11077106B2 (en) 2021-08-03
TWI874925B (zh) 2025-03-01
US20220110935A1 (en) 2022-04-14
UA126336C2 (uk) 2022-09-21
CA3049737A1 (en) 2018-08-09
MX2022007955A (es) 2022-07-27
CN110198716A (zh) 2019-09-03
AU2018216969A1 (en) 2019-07-25
HUE062453T2 (hu) 2023-11-28
JOP20190190A1 (ar) 2019-08-04
KR20190110581A (ko) 2019-09-30
BR112019016043A2 (pt) 2020-03-31
SG10202105110VA (en) 2021-06-29
RS64778B1 (sr) 2023-11-30
EP3576740B1 (en) 2023-06-14
EP3576740A1 (en) 2019-12-11
PL3576740T3 (pl) 2023-09-11
PH12019501885A1 (en) 2020-06-29
FI3576740T3 (fi) 2023-08-31
JOP20190190B1 (ar) 2024-04-18
NZ796822A (en) 2025-12-19
AU2018216969B2 (en) 2024-04-11
AU2024201871A1 (en) 2024-04-11
SI3576740T1 (sl) 2023-10-30

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