JP2020505044A5 - - Google Patents

Download PDF

Info

Publication number
JP2020505044A5
JP2020505044A5 JP2019540095A JP2019540095A JP2020505044A5 JP 2020505044 A5 JP2020505044 A5 JP 2020505044A5 JP 2019540095 A JP2019540095 A JP 2019540095A JP 2019540095 A JP2019540095 A JP 2019540095A JP 2020505044 A5 JP2020505044 A5 JP 2020505044A5
Authority
JP
Japan
Prior art keywords
cell
genetically modified
protein
composition
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2019540095A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020505044A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2018/015180 external-priority patent/WO2018140573A1/en
Publication of JP2020505044A publication Critical patent/JP2020505044A/ja
Publication of JP2020505044A5 publication Critical patent/JP2020505044A5/ja
Priority to JP2022173206A priority Critical patent/JP2022191524A/ja
Withdrawn legal-status Critical Current

Links

JP2019540095A 2017-01-26 2018-01-25 B細胞操作 Withdrawn JP2020505044A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022173206A JP2022191524A (ja) 2017-01-26 2022-10-28 B細胞操作

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762450917P 2017-01-26 2017-01-26
US62/450,917 2017-01-26
PCT/US2018/015180 WO2018140573A1 (en) 2017-01-26 2018-01-25 B-cell engineering

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022173206A Division JP2022191524A (ja) 2017-01-26 2022-10-28 B細胞操作

Publications (2)

Publication Number Publication Date
JP2020505044A JP2020505044A (ja) 2020-02-20
JP2020505044A5 true JP2020505044A5 (enExample) 2020-12-17

Family

ID=62979713

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019540095A Withdrawn JP2020505044A (ja) 2017-01-26 2018-01-25 B細胞操作
JP2022173206A Pending JP2022191524A (ja) 2017-01-26 2022-10-28 B細胞操作

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022173206A Pending JP2022191524A (ja) 2017-01-26 2022-10-28 B細胞操作

Country Status (11)

Country Link
US (1) US20190352614A1 (enExample)
EP (1) EP3573464A4 (enExample)
JP (2) JP2020505044A (enExample)
KR (1) KR20190111063A (enExample)
CN (1) CN110536963A (enExample)
AU (1) AU2018212652B2 (enExample)
BR (1) BR112019015355A2 (enExample)
CA (1) CA3051113A1 (enExample)
IL (1) IL268110B2 (enExample)
MX (1) MX2019008844A (enExample)
WO (1) WO2018140573A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9725710B2 (en) 2014-01-08 2017-08-08 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
CN110536963A (zh) * 2017-01-26 2019-12-03 桑格摩生物治疗股份有限公司 B细胞工程改造
AU2018235957B2 (en) 2017-03-16 2024-02-01 Seattle Children's Hospital (dba Seattle Children's Research Institute) Engraftable cell-based immunotherapy for long-term delivery of therapeutic proteins
JP2021507561A (ja) 2017-12-14 2021-02-22 フロデザイン ソニックス, インク.Flodesign Sonics, Inc. 音響トランスデューサドライバ及びコントローラ
EP3867380A2 (en) 2018-10-18 2021-08-25 Intellia Therapeutics, Inc. Compositions and methods for expressing factor ix
EP4070855B1 (en) 2019-11-01 2025-12-24 Kyoto Prefectural Public University Corporation B-cell antibody receptor and use thereof
EP4127188A4 (en) 2020-03-31 2024-08-21 Walking Fish Therapeutics MODIFIED B CELLS AND METHODS OF USE THEREOF
US20260048123A1 (en) * 2022-03-30 2026-02-19 Fred Hutchinson Cancer Center Systems and methods to produce b cells that express selected antibodies and gene products
WO2024151683A2 (en) * 2023-01-09 2024-07-18 Walking Fish Therapeutics, Inc. HUMAN B CELL ENGINEERED TO EXPRESS IgA AND IgM ANTIBODIES FOR THERAPEUTIC USE
WO2024196669A2 (en) * 2023-03-17 2024-09-26 Walking Fish Therapeutics, Inc. Methods for in vivo editing of b cells
EP4698191A2 (en) * 2023-04-17 2026-02-25 Be Biopharma, Inc. Engineered cell preparations for treatment of niemann pick b disease

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003901511A0 (en) * 2003-03-28 2003-04-17 Bionomics Limited Nucleic acid molecules associated with angiogenesis II
ES2436741T3 (es) * 2004-09-22 2014-01-07 St. Jude Children's Research Hospital Expresión mejorada de Factor IX en vectores de terapia génica
JP6215533B2 (ja) * 2009-04-09 2017-10-18 サンガモ セラピューティクス, インコーポレイテッド 幹細胞への標的組込み
CN116083487A (zh) * 2013-05-15 2023-05-09 桑格摩生物治疗股份有限公司 用于治疗遗传病状的方法和组合物
US9757420B2 (en) * 2014-07-25 2017-09-12 Sangamo Therapeutics, Inc. Gene editing for HIV gene therapy
CN113699113A (zh) * 2014-09-16 2021-11-26 桑格摩治疗股份有限公司 用于造血干细胞中核酸酶介导的基因组工程化和校正的方法和组合物
EP3234107B1 (en) * 2014-12-19 2022-09-14 Immusoft Corporation B cells for in vivo delivery of therapeutic agents
ES2959608T3 (es) * 2015-04-03 2024-02-27 Dana Farber Cancer Inst Inc Composición y métodos de edición del genoma de células B
PE20181090A1 (es) * 2015-06-24 2018-07-09 Janssen Biotech Inc Modulacion y tratamiento inmunes de tumores solidos con anticuerpos que se unen especificamente a cd38
AU2016291778B2 (en) * 2015-07-13 2021-05-06 Sangamo Therapeutics, Inc. Delivery methods and compositions for nuclease-mediated genome engineering
ES2895430T3 (es) * 2016-01-15 2022-02-21 Univ Minnesota Métodos y composiciones para el tratamiento de enfermedad neurológica
CN110536963A (zh) * 2017-01-26 2019-12-03 桑格摩生物治疗股份有限公司 B细胞工程改造
CR20190509A (es) * 2017-04-10 2020-01-08 Immatics Biotechnologies Gmbh Péptidos y combinaciones de péptidos para el uso en la inmunoterapia contra la leucemia y otros tipos de cáncer
EP3638783A4 (en) * 2017-06-16 2021-03-10 Sangamo Therapeutics, Inc. TARGETED T-LYMPHOCYTE AND / OR HLA RECEPTOR INTERRUPTION
WO2019032675A1 (en) * 2017-08-08 2019-02-14 Sangamo Therapeutics, Inc. CELL TARGETING MEDIATED BY A CHIMERIC ANTIGEN RECEPTOR
JP2021502085A (ja) * 2017-11-09 2021-01-28 サンガモ セラピューティクス, インコーポレイテッド サイトカイン誘導性sh2含有タンパク質(cish)遺伝子の遺伝子改変
US20230158070A1 (en) * 2018-01-30 2023-05-25 Cellectis Combination comprising allogeneic immune cells deficient for an antigen present on both t-cells and pathological cells and therapeutic antibody against said antigen
AU2019327913A1 (en) * 2018-08-29 2021-03-18 Nanjing Legend Biotech Co., Ltd. Anti-mesothelin chimeric antigen receptor (CAR) constructs and uses thereof
EP3887395A4 (en) * 2018-11-30 2022-07-27 Intima Bioscience, Inc. METHODS FOR IDENTIFICATION OF IMMUNOMODULATORY GENES

Similar Documents

Publication Publication Date Title
JP2020505044A5 (enExample)
Wienert et al. Wake-up sleepy gene: reactivating fetal globin for β-hemoglobinopathies
Staal et al. Autologous stem-cell-based gene therapy for inherited disorders: state of the art and perspectives
JP2017500061A5 (enExample)
Xi et al. Genetically engineered pigs for xenotransplantation: Hopes and challenges
Hudecek et al. Going non-viral: the Sleeping Beauty transposon system breaks on through to the clinical side
JP2020500162A5 (enExample)
JP2016539627A5 (enExample)
Amelio et al. p63 the guardian of human reproduction
Kohn Gene therapy for blood diseases
JP2017504354A5 (enExample)
US12385070B2 (en) Homology directed repair compositions for the treatment of hemoglobinopathies
Paladini et al. The multifaceted nature of aminopeptidases ERAP1, ERAP2, and LNPEP: from evolution to disease
Naeimi Kararoudi et al. Clustered regularly interspaced short palindromic repeats/Cas9 gene editing technique in xenotransplantation
Bueren et al. Advances in the gene therapy of monogenic blood cell diseases
Shi et al. Platelets as delivery systems for disease treatments
ES3032739T3 (en) Genetically engineered hematopoietic stem cell as a platform for systemic protein expression
Patel et al. The immune response to the fVIII gene therapy in preclinical models
Crossley et al. Effective therapies for sickle cell disease: are we there yet?
Ly et al. Gene therapy in the treatment of heart failure
EP3765617A1 (en) Systems and methods for the treatment of hemoglobinopathies
Bottino et al. Use of genetically-engineered pig donors in islet transplantation
Březina et al. Mechanisms of direct and indirect presentation of self-antigens in the thymus
Naldini et al. The EHA research roadmap: hematopoietic stem cell gene therapy
Barbarani et al. β-Hemoglobinopathies: the test bench for genome editing-based therapeutic strategies