JP2020504722A - 血管密度を増加させる方法 - Google Patents
血管密度を増加させる方法 Download PDFInfo
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- JP2020504722A JP2020504722A JP2019533084A JP2019533084A JP2020504722A JP 2020504722 A JP2020504722 A JP 2020504722A JP 2019533084 A JP2019533084 A JP 2019533084A JP 2019533084 A JP2019533084 A JP 2019533084A JP 2020504722 A JP2020504722 A JP 2020504722A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
- C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Vascular Medicine (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2016905310A AU2016905310A0 (en) | 2016-12-21 | Methods for enhancing vascular density | |
| AU2016905310 | 2016-12-21 | ||
| PCT/AU2017/051435 WO2018112541A1 (en) | 2016-12-21 | 2017-12-21 | Methods for enhancing vascular density |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020504722A true JP2020504722A (ja) | 2020-02-13 |
| JP2020504722A5 JP2020504722A5 (cg-RX-API-DMAC7.html) | 2021-02-04 |
Family
ID=62624132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019533084A Pending JP2020504722A (ja) | 2016-12-21 | 2017-12-21 | 血管密度を増加させる方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20190328761A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3558312A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2020504722A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20190110547A (cg-RX-API-DMAC7.html) |
| CN (2) | CN116509885A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017383100B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3047437A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018112541A1 (cg-RX-API-DMAC7.html) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7555159B1 (ja) * | 2023-06-29 | 2024-09-24 | 株式会社レースホース | 動物用栄養組成物 |
| WO2024237195A1 (ja) | 2023-05-12 | 2024-11-21 | 明治ホールディングス株式会社 | 子どもの発達促進のための組成物 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3331894B1 (en) | 2015-08-05 | 2021-02-17 | Metro International Biotech, LLC | Nicotinamide mononucleotide derivatives and their uses |
| GB2542881B (en) | 2015-10-02 | 2020-01-01 | Carr Andrew | Crystal forms of ß-nicotinamide mononucleotide |
| CN109674808A (zh) * | 2019-01-30 | 2019-04-26 | 四川大学 | β-烟酰胺单核苷酸或其前体在制备延缓肺衰老药物中的用途 |
| CN110638826A (zh) * | 2019-10-09 | 2020-01-03 | 泓博元生命科技(深圳)有限公司 | Nadh和/或nmn在制备肌肉增强或抑制肌肉量下降的药物或保健品中的应用 |
| CN110734950A (zh) * | 2019-11-14 | 2020-01-31 | 南方医科大学珠江医院 | 一种nmn治疗与改善cmva的相关性的体外实验法 |
| CN110974781A (zh) * | 2020-01-02 | 2020-04-10 | 崔立峰 | 一种用于皮肤创面修复的凝胶 |
| IL296262A (en) * | 2020-03-11 | 2022-11-01 | Massachusetts Eye & Ear Infirmary | Gene therapy for nmnat1-related retinal degeneration |
| EP4070799A1 (en) * | 2021-04-08 | 2022-10-12 | Nuvamid SA | Compositions for the improvement of sport performance |
| WO2023159601A1 (en) * | 2022-02-28 | 2023-08-31 | Shenzhen University | Use of agent deacetylating klf4 to promote transcriptional activity thereof, method for maintaining functions of pulmonary artery endothelial cells, and method for treating pulmonary arterial hypertension |
| CN115227712A (zh) * | 2022-07-26 | 2022-10-25 | 上海市第五人民医院 | NaHS在制备治疗骨质疏松药物中的应用 |
| CN117771375A (zh) * | 2024-01-31 | 2024-03-29 | 中山大学附属第三医院 | SIRT1/PGC-1α通路激活剂的新用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008501343A (ja) * | 2004-06-04 | 2008-01-24 | ワシントン・ユニバーシティ | 神経障害を治療するための方法および組成物 |
| WO2016086088A2 (en) * | 2014-11-25 | 2016-06-02 | Northwestern University | Wound healing through sirt1 overexpression |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1853590A1 (en) * | 2005-03-03 | 2007-11-14 | Sirtris Pharmaceuticals, Inc. | Fused heterocyclic compounds and their use as sirtuin modulators |
| US7855289B2 (en) * | 2005-08-04 | 2010-12-21 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
| CN102985553B (zh) * | 2010-04-15 | 2015-11-25 | 西特里斯药业公司 | 沉默调节蛋白活化剂和活化测定 |
| US20140065099A1 (en) * | 2011-02-15 | 2014-03-06 | Ecole Polytechnique Federale De Lausanne (Epfl) | Methods of Treating Mitochondrial Dysfunction |
| WO2013002879A1 (en) * | 2011-06-29 | 2013-01-03 | President And Fellows Of Harvard College | Small molecule cd38 inhibitors and methods of using same |
| US9877981B2 (en) * | 2012-10-09 | 2018-01-30 | President And Fellows Of Harvard College | NAD biosynthesis and precursors for the treatment and prevention of cancer and proliferation |
| US20170087180A1 (en) * | 2014-06-03 | 2017-03-30 | Sulfagenix, Inc. | Methods and compositions for treating nitric oxide deficiency disorders and related conditions |
-
2017
- 2017-12-21 WO PCT/AU2017/051435 patent/WO2018112541A1/en not_active Ceased
- 2017-12-21 EP EP17883855.3A patent/EP3558312A4/en not_active Withdrawn
- 2017-12-21 AU AU2017383100A patent/AU2017383100B2/en active Active
- 2017-12-21 CN CN202310533025.7A patent/CN116509885A/zh active Pending
- 2017-12-21 KR KR1020197021500A patent/KR20190110547A/ko not_active Ceased
- 2017-12-21 CN CN201780086403.4A patent/CN110325190A/zh active Pending
- 2017-12-21 JP JP2019533084A patent/JP2020504722A/ja active Pending
- 2017-12-21 US US16/471,653 patent/US20190328761A1/en not_active Abandoned
- 2017-12-21 CA CA3047437A patent/CA3047437A1/en active Pending
-
2023
- 2023-01-20 US US18/157,510 patent/US20230149437A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008501343A (ja) * | 2004-06-04 | 2008-01-24 | ワシントン・ユニバーシティ | 神経障害を治療するための方法および組成物 |
| WO2016086088A2 (en) * | 2014-11-25 | 2016-06-02 | Northwestern University | Wound healing through sirt1 overexpression |
Non-Patent Citations (5)
| Title |
|---|
| AGEING RESEARCH REVIEWS, vol. 21, JPN6021043126, 2015, pages 1 - 15, ISSN: 0005027149 * |
| FOOD AND CHEMICAL TOXICOLOGY, vol. 61, JPN6022027463, 2013, pages 53 - 59, ISSN: 0004817866 * |
| HYPERTENSION, vol. Vol.68, Issue suppl_1, JPN6021043121, 13 December 2016 (2016-12-13), pages 141, ISSN: 0005027151 * |
| MOLECULAR AND CELLULAR BIOLOGY, vol. 33, no. 6, JPN6021043123, 2013, pages 1104 - 1113, ISSN: 0005027150 * |
| ビタミン, vol. 90, JPN6021043124, June 2016 (2016-06-01), pages 286 - 289, ISSN: 0004817867 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024237195A1 (ja) | 2023-05-12 | 2024-11-21 | 明治ホールディングス株式会社 | 子どもの発達促進のための組成物 |
| JP7555159B1 (ja) * | 2023-06-29 | 2024-09-24 | 株式会社レースホース | 動物用栄養組成物 |
| WO2025004279A1 (ja) * | 2023-06-29 | 2025-01-02 | 株式会社レースホース | 動物用栄養組成物 |
| JP2025010131A (ja) * | 2023-06-29 | 2025-01-20 | 株式会社レースホース | 動物用栄養組成物 |
| JP7674710B2 (ja) | 2023-06-29 | 2025-05-12 | 株式会社希星 | 動物用栄養組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3558312A4 (en) | 2021-01-13 |
| KR20190110547A (ko) | 2019-09-30 |
| CN116509885A (zh) | 2023-08-01 |
| US20190328761A1 (en) | 2019-10-31 |
| CN110325190A (zh) | 2019-10-11 |
| AU2017383100A1 (en) | 2019-07-18 |
| EP3558312A1 (en) | 2019-10-30 |
| WO2018112541A1 (en) | 2018-06-28 |
| US20230149437A1 (en) | 2023-05-18 |
| CA3047437A1 (en) | 2018-06-28 |
| AU2017383100B2 (en) | 2023-04-06 |
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