JP2020502104A5 - - Google Patents
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- Publication number
- JP2020502104A5 JP2020502104A5 JP2019531589A JP2019531589A JP2020502104A5 JP 2020502104 A5 JP2020502104 A5 JP 2020502104A5 JP 2019531589 A JP2019531589 A JP 2019531589A JP 2019531589 A JP2019531589 A JP 2019531589A JP 2020502104 A5 JP2020502104 A5 JP 2020502104A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- chain
- protein
- selenocysteine
- residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022184852A JP7378106B2 (ja) | 2016-08-30 | 2022-11-18 | ゲノム的に再コードした生物におけるセレノ－生物製剤の製造 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381316P | 2016-08-30 | 2016-08-30 | |
| US62/381,316 | 2016-08-30 | ||
| US201762537986P | 2017-07-28 | 2017-07-28 | |
| US62/537,986 | 2017-07-28 | ||
| PCT/US2017/049354 WO2018045018A1 (en) | 2016-08-30 | 2017-08-30 | Production of seleno-biologics in genomically recoded organisms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022184852A Division JP7378106B2 (ja) | 2016-08-30 | 2022-11-18 | ゲノム的に再コードした生物におけるセレノ－生物製剤の製造 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020502104A JP2020502104A (ja) | 2020-01-23 |
| JP2020502104A5 true JP2020502104A5 (https=) | 2020-10-08 |
| JP7186400B2 JP7186400B2 (ja) | 2022-12-09 |
Family
ID=61301655
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531589A Active JP7186400B2 (ja) | 2016-08-30 | 2017-08-30 | ゲノム的に再コードした生物におけるセレノ－生物製剤の製造 |
| JP2022184852A Active JP7378106B2 (ja) | 2016-08-30 | 2022-11-18 | ゲノム的に再コードした生物におけるセレノ－生物製剤の製造 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022184852A Active JP7378106B2 (ja) | 2016-08-30 | 2022-11-18 | ゲノム的に再コードした生物におけるセレノ－生物製剤の製造 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11492650B2 (https=) |
| EP (1) | EP3506945A4 (https=) |
| JP (2) | JP7186400B2 (https=) |
| CN (1) | CN109803679A (https=) |
| WO (1) | WO2018045018A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR20250057128A (ko) | 2015-12-30 | 2025-04-28 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| US11542332B2 (en) | 2016-03-26 | 2023-01-03 | Bioatla, Inc. | Anti-CTLA4 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| US11155804B2 (en) | 2016-07-11 | 2021-10-26 | Board Of Regents, The University Of Texas System | Recombinant polypeptides comprising selenocysteine and method for producing the same |
| EP3758737A4 (en) | 2018-03-02 | 2022-10-12 | Kodiak Sciences Inc. | IL-6 ANTIBODIES AND FUSION CONSTRUCTS AND CONJUGATES THEREOF |
| EP3821003A4 (en) * | 2018-07-09 | 2022-07-20 | Gro Biosciences Inc. | Non-standard amino acid containing compositions and uses thereof |
| US20220144915A1 (en) * | 2019-04-19 | 2022-05-12 | The Trustees Of Indiana University | Stabilization of prandial or basal insulin analogues by an internal diselenide bridge |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| US20230242655A1 (en) | 2019-12-03 | 2023-08-03 | Evotec International Gmbh | Interferon-associated antigen binding proteins and uses thereof |
| JP7735291B2 (ja) | 2020-02-21 | 2025-09-08 | エーアールエス ファーマシューティカルズ、インコーポレイテッド | ネクチン－４抗体コンジュゲートおよびその使用 |
| CN113512116B (zh) * | 2020-04-10 | 2022-09-20 | 苏州普乐康医药科技有限公司 | 一种抗igf-1r抗体及其应用 |
| US20220267450A1 (en) | 2020-10-14 | 2022-08-25 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| EP4384219A4 (en) | 2021-08-10 | 2025-06-18 | Viridian Therapeutics, Inc. | COMPOSITIONS, DOSAGES AND METHODS FOR THE TREATMENT OF THYROID EYE DISEASE |
| CN118076644A (zh) * | 2021-09-30 | 2024-05-24 | 正大天晴药业集团股份有限公司 | 针对免疫检查点的双特异性抗体 |
| WO2025170982A2 (en) | 2024-02-06 | 2025-08-14 | Paragon Therapeutics, Inc. | Il-23 antibody compositions and methods of use |
| WO2025222144A1 (en) * | 2024-04-18 | 2025-10-23 | Fred Hutchinson Cancer Center | Antibodies and vaccines having vh3-21 and vl1-40 binding domains and uses thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6849417B1 (en) | 1998-04-06 | 2005-02-01 | The United States Of America As Represented By The Department Of Health And Human Services | Mammalian selenoprotein differentially expressed in tumor cells |
| AU6987200A (en) | 1999-08-16 | 2001-03-13 | Karolinska Innovations Ab | Methods and means for selenoprotein expression |
| WO2007075438A2 (en) | 2005-12-15 | 2007-07-05 | Codon Devices, Inc. | Polypeptides comprising unnatural amino acids, methods for their production and uses therefor |
| WO2009043051A2 (en) * | 2007-09-27 | 2009-04-02 | Biogen Idec Ma Inc. | Cd23 binding molecules and methods of use thereof |
| AU2012216723B2 (en) * | 2007-11-20 | 2014-08-28 | Ambrx, Inc. | Modified insulin polypeptides and their uses |
| MX2010005317A (es) * | 2007-11-20 | 2010-06-02 | Ambrx Inc | Polipeptidos de insulina modificados y sus usos. |
| JP5572972B2 (ja) * | 2009-03-16 | 2014-08-20 | Ｊｎｃ株式会社 | インスリン分泌促進剤などの薬物のスクリーニング方法 |
| EP2614076A4 (en) * | 2010-09-08 | 2014-03-05 | Florey Howard Inst | CHANGED RELAXIN POLYPEPTIDES |
| JP6093715B2 (ja) | 2011-01-28 | 2017-03-08 | ナショナル リサーチ カウンシル オブ カナダ | 免疫グロブリンドメインの工学的作製 |
| US9486507B2 (en) | 2011-06-10 | 2016-11-08 | Biogen Ma Inc. | Pro-coagulant compounds and methods of use thereof |
| US10240158B2 (en) | 2011-07-11 | 2019-03-26 | Yale University | Compositions and methods for making selenocysteine containing polypeptides |
| WO2013009868A1 (en) | 2011-07-11 | 2013-01-17 | Yale University | Compositions and methods for making selenocysteine containing polypeptides |
| US10876142B2 (en) | 2011-07-11 | 2020-12-29 | Yale University | Compositions and methods for making selenocysteine containing polypeptides |
| CN105283201B (zh) | 2013-03-14 | 2019-08-02 | 斯克利普斯研究所 | 靶向剂抗体偶联物及其用途 |
| US20150050682A1 (en) | 2013-08-15 | 2015-02-19 | University Of Vermont And State Agricultural College | Direct assay of thioredoxin reductase activity |
| US10519247B2 (en) * | 2013-11-01 | 2019-12-31 | Board Of Regents,The University Of Texas System | Targeting HER2 and HER3 with bispecific antibodies in cancerous cells |
| US10118950B2 (en) | 2014-08-30 | 2018-11-06 | Northwestern University | Platforms for cell-free protein synthesis comprising extracts from genomically recoded E. coli strains having genetic knock-out mutations in release factor 1 (RF-1) and endA |
| WO2016172269A2 (en) | 2015-04-20 | 2016-10-27 | University Of Utah Research Foundation | Insulin analogs having shortened b chain peptides and associated methods |
| CN105111304B (zh) * | 2015-09-30 | 2018-12-14 | 山东阿华生物药业有限公司 | 重组人胰岛素前体的纯化和酶切转换方法 |
| US10557160B2 (en) | 2015-12-15 | 2020-02-11 | Board Of Regents, The University Of Texas System | Transgenic bacteria with expanded amino acid usage and nucleic acid molecules for use in the same |
| WO2018014091A1 (en) | 2016-07-22 | 2018-01-25 | University Of Utah Research Foundation | Insulin analogs |
| US11155804B2 (en) | 2016-07-11 | 2021-10-26 | Board Of Regents, The University Of Texas System | Recombinant polypeptides comprising selenocysteine and method for producing the same |
| BR112019000991A2 (pt) * | 2016-07-22 | 2019-07-02 | University Of Utah Research Foundation | análogo da insulina, composição farmacêutica, método para tratar e/ou prevenir uma afeção relacionada com insulina, método para decrescer níveis de glicose no sangue, uso do análogo da insulina, método de replanejamento ou modificação de um polipeptídeo que é conhecido por se ligar a um receptor da insulina, polipeptídeo, molécula isolada, método para identificar um composto que se liga ao receptor de insulina, método de base computacional para identificar um composto que imita a atividade da insulina, composto identificado usando um método, cristal do polipeptídeo, estrutura do polipeptídeo, uso da estrutura, uso do modelo estrutural, peptídeo, método para aumentar a ativação do receptor da insulina em um sujeito, método para diminuir o açúcar no sangue em um sujeito, método para tratar diabetes tipo 1 em um sujeito e proteína terapêutica |
| US20220144915A1 (en) | 2019-04-19 | 2022-05-12 | The Trustees Of Indiana University | Stabilization of prandial or basal insulin analogues by an internal diselenide bridge |
-
2017
- 2017-08-30 CN CN201780053385.XA patent/CN109803679A/zh active Pending
- 2017-08-30 EP EP17847457.3A patent/EP3506945A4/en active Pending
- 2017-08-30 WO PCT/US2017/049354 patent/WO2018045018A1/en not_active Ceased
- 2017-08-30 JP JP2019531589A patent/JP7186400B2/ja active Active
- 2017-08-30 US US16/329,761 patent/US11492650B2/en active Active
-
2022
- 2022-11-18 JP JP2022184852A patent/JP7378106B2/ja active Active
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