JP2020501517A5 - - Google Patents
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- JP2020501517A5 JP2020501517A5 JP2019522657A JP2019522657A JP2020501517A5 JP 2020501517 A5 JP2020501517 A5 JP 2020501517A5 JP 2019522657 A JP2019522657 A JP 2019522657A JP 2019522657 A JP2019522657 A JP 2019522657A JP 2020501517 A5 JP2020501517 A5 JP 2020501517A5
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- Prior art keywords
- cancer
- cdna
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- drug
- droplets
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022142901A JP7441907B2 (ja) | 2016-10-27 | 2022-09-08 | 特定のがんに対するがん療法についてその有効性を判定するための血液サンプルのデジタル分析 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662413952P | 2016-10-27 | 2016-10-27 | |
| US62/413,952 | 2016-10-27 | ||
| PCT/US2017/058855 WO2018081625A2 (en) | 2016-10-27 | 2017-10-27 | Digital analysis of blood samples to determine efficacy of cancer therapies for specific cancers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022142901A Division JP7441907B2 (ja) | 2016-10-27 | 2022-09-08 | 特定のがんに対するがん療法についてその有効性を判定するための血液サンプルのデジタル分析 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020501517A JP2020501517A (ja) | 2020-01-23 |
| JP2020501517A5 true JP2020501517A5 (https=) | 2020-12-03 |
| JP7195252B2 JP7195252B2 (ja) | 2022-12-23 |
Family
ID=62025512
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522657A Active JP7195252B2 (ja) | 2016-10-27 | 2017-10-27 | 特定のがんに対するがん療法についてその有効性を判定するための血液サンプルのデジタル分析 |
| JP2022142901A Active JP7441907B2 (ja) | 2016-10-27 | 2022-09-08 | 特定のがんに対するがん療法についてその有効性を判定するための血液サンプルのデジタル分析 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022142901A Active JP7441907B2 (ja) | 2016-10-27 | 2022-09-08 | 特定のがんに対するがん療法についてその有効性を判定するための血液サンプルのデジタル分析 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11371101B2 (https=) |
| EP (2) | EP3532642B1 (https=) |
| JP (2) | JP7195252B2 (https=) |
| CN (1) | CN110050075B (https=) |
| WO (1) | WO2018081625A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016238253B2 (en) | 2015-03-25 | 2022-06-16 | The General Hospital Corporation | Digital analysis of circulating tumor cells in blood samples |
| CN110050075B (zh) * | 2016-10-27 | 2024-04-02 | 通用医疗公司 | 用于确定特定癌症的癌症疗法的功效的血液样品的数字分析 |
| WO2020006098A2 (en) * | 2018-06-26 | 2020-01-02 | Children's National Medical Center | Tumor-associated markers for detection of minimal residual disease using digital droplet pcr |
| WO2020102506A1 (en) * | 2018-11-14 | 2020-05-22 | The Broad Institute, Inc. | Aryl hydrocarbon receptor (ahr) activator compounds as cancer therapeutics |
| TWI790399B (zh) * | 2019-08-30 | 2023-01-21 | 長庚大學 | 循環腫瘤細胞資訊評估方法及其分析方法 |
| JP2022547735A (ja) * | 2019-09-16 | 2022-11-15 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 乳房がんの分子特徴付けに基づく処置の方法 |
| JP7534426B2 (ja) * | 2020-09-09 | 2024-08-14 | 株式会社日立ハイテク | 代謝物パネルによるがん検査法 |
| CN112698033A (zh) * | 2020-12-09 | 2021-04-23 | 复旦大学附属中山医院 | 一种血源性外泌体her2的检测方法及其应用 |
| US20240159632A1 (en) * | 2021-03-16 | 2024-05-16 | Sony Group Corporation | Closed-system automated sample sorting system |
| CN113292643A (zh) * | 2021-05-31 | 2021-08-24 | 南京市第二医院 | 一种肝癌肿瘤标志物及其应用 |
| JP2024527371A (ja) * | 2021-07-08 | 2024-07-24 | オウロテック インコーポレイテッド | 処置の有効性予測システム及び方法 |
| CN114395622A (zh) * | 2021-12-13 | 2022-04-26 | 深圳先进技术研究院 | 一种利用数字pcr检测循环肿瘤细胞egfr基因突变的方法及其应用 |
| WO2025259592A1 (en) * | 2024-06-10 | 2025-12-18 | Genecentric Therapeutics, Inc. | Therapeutic predictive response signatures and uses thereof in cancer patients |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US889A (en) | 1838-08-20 | Mode of constructing metal bench-vises | ||
| US8535A (en) | 1851-11-18 | Stove-geate | ||
| DE29623597U1 (de) | 1996-11-08 | 1999-01-07 | Eppendorf - Netheler - Hinz Gmbh, 22339 Hamburg | Temperierblock mit Temperiereinrichtungen |
| US20080050393A1 (en) | 1998-12-03 | 2008-02-28 | Tang Y Tom | Novel nucleic acids and polypeptides |
| CA2311201A1 (en) | 1999-08-05 | 2001-02-05 | Genset S.A. | Ests and encoded human proteins |
| US20030143539A1 (en) | 2000-12-08 | 2003-07-31 | Francois Bertucci | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
| JP2005512510A (ja) | 2001-05-16 | 2005-05-12 | ノバルティス アクチエンゲゼルシャフト | 予後および治療標的として乳癌で発現される遺伝子 |
| US20030073623A1 (en) | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
| US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| US20060275794A1 (en) | 2005-03-07 | 2006-12-07 | Invitrogen Corporation | Collections of matched biological reagents and methods for identifying matched reagents |
| US20070026417A1 (en) | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| US20090118175A1 (en) * | 2005-05-06 | 2009-05-07 | Macina Roberto A | Compositions and Methods for Detection, Prognosis and Treatment of Breast Cancer |
| CA2652052A1 (en) | 2006-05-16 | 2007-11-29 | Nugen Technologies, Inc. | Nucleic acid separation and purification method based on reversible charge interactions |
| EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| WO2009051734A1 (en) | 2007-10-17 | 2009-04-23 | The General Hospital Corporation | Microchip-based devices for capturing circulating tumor cells and methods of their use |
| US9068181B2 (en) | 2008-05-23 | 2015-06-30 | The General Hospital Corporation | Microfluidic droplet encapsulation |
| US20120252015A1 (en) | 2011-02-18 | 2012-10-04 | Bio-Rad Laboratories | Methods and compositions for detecting genetic material |
| US20100162416A1 (en) | 2008-09-29 | 2010-06-24 | Stemlifeline, Inc. | Multi-stage stem cell carcinogenesis |
| US9625454B2 (en) | 2009-09-04 | 2017-04-18 | The Research Foundation For The State University Of New York | Rapid and continuous analyte processing in droplet microfluidic devices |
| US20110166030A1 (en) | 2009-09-30 | 2011-07-07 | Yixin Wang | Prediction of response to docetaxel therapy based on the presence of TMPRSSG2:ERG fusion in circulating tumor cells |
| CA2789425C (en) | 2010-02-12 | 2020-04-28 | Raindance Technologies, Inc. | Digital analyte analysis with polymerase error correction |
| US20120329061A1 (en) | 2010-03-11 | 2012-12-27 | Board Of Regents, The University Of Texas System | Quantitative rt-pcr detection for genes involved in epithelial mesenchymal transition in peripheral blood of cancer patients |
| AU2015268617A1 (en) * | 2010-03-31 | 2016-01-07 | Sividon Diagnostics Gmbh | Method for breast cancer recurrence prediction under endocrine treatment |
| ES2525382T3 (es) * | 2010-03-31 | 2014-12-23 | Sividon Diagnostics Gmbh | Método para la predicción de recurrencia del cáncer de mama bajo tratamiento endocrino |
| US9650629B2 (en) | 2010-07-07 | 2017-05-16 | Roche Molecular Systems, Inc. | Clonal pre-amplification in emulsion |
| JP2013540995A (ja) * | 2010-08-18 | 2013-11-07 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス エス．アー．エール．エル． | 疾患に対する循環バイオマーカー |
| WO2012115885A1 (en) | 2011-02-22 | 2012-08-30 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers |
| WO2012135397A2 (en) * | 2011-03-29 | 2012-10-04 | Lisanti Michael P | Lactate-and ketones-induced gene signatures and use the same for diagnosing disease and predicting clinical outcome |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| GB2510539B (en) | 2011-10-24 | 2016-04-20 | Gen Hospital Corp | Biomarkers of cancer |
| US9766244B2 (en) * | 2012-07-02 | 2017-09-19 | The General Hospital Corporation | Diagnosis and monitoring treatment of prostate cancer |
| AU2013302867A1 (en) | 2012-08-13 | 2015-02-26 | The Regents Of The University Of California | Methods and systems for detecting biological components |
| CA2884820A1 (en) | 2012-09-14 | 2014-03-20 | Memorial Sloan-Kettering Cancer Center | Genes associated with dasatinib sensitivity |
| US9671405B2 (en) * | 2012-09-19 | 2017-06-06 | Cornell University | Identifying taxane sensitivity in prostate cancer patients |
| US20140154681A1 (en) * | 2012-11-12 | 2014-06-05 | Nanostring Technologies, Inc. | Methods to Predict Breast Cancer Outcome |
| WO2014165762A1 (en) | 2013-04-05 | 2014-10-09 | Raindance Technologies, Inc. | Rare cell analysis after negative selection |
| CA2920317A1 (en) | 2013-08-12 | 2015-02-19 | Tokai Pharmaceuticals, Inc. | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
| EP3058316B1 (en) | 2013-10-18 | 2019-03-13 | The General Hospital Corporation | Microfluidic sorting using high gradient magnetic fields |
| CA2941161A1 (en) * | 2014-03-13 | 2015-09-17 | F.Hoffmann-La Roche Ag | Methods and compositions for modulating estrogen receptor mutants |
| MA40271A (fr) * | 2014-05-21 | 2017-03-29 | Hoffmann La Roche | Procédés pour traiter le cancer du sein luminal a pr-positif, avec un inhibiteur de pi3k, pictilisib |
| DK3230736T3 (da) * | 2014-12-12 | 2020-06-08 | Celcuity Inc | Fremgangsmåder til måling af ErbB-signaleringsvejsaktivitet til at diagnosticere og behandle cancerpatienter |
| EP3259375B1 (en) | 2015-02-20 | 2019-01-09 | Comelz S.p.a. | Method for cutting natural hides |
| US20160304962A1 (en) | 2015-03-12 | 2016-10-20 | Janssen Pharmaceutica Nv | WHOLE BLOOD BASED mRNA MARKERS FOR PREDICTING PROSTATE CANCER AND METHODS OF DETECTING THE SAME |
| AU2016238253B2 (en) | 2015-03-25 | 2022-06-16 | The General Hospital Corporation | Digital analysis of circulating tumor cells in blood samples |
| CN110050075B (zh) * | 2016-10-27 | 2024-04-02 | 通用医疗公司 | 用于确定特定癌症的癌症疗法的功效的血液样品的数字分析 |
-
2017
- 2017-10-27 CN CN201780075515.XA patent/CN110050075B/zh active Active
- 2017-10-27 JP JP2019522657A patent/JP7195252B2/ja active Active
- 2017-10-27 US US16/344,557 patent/US11371101B2/en active Active
- 2017-10-27 WO PCT/US2017/058855 patent/WO2018081625A2/en not_active Ceased
- 2017-10-27 EP EP17865612.0A patent/EP3532642B1/en active Active
- 2017-10-27 EP EP21212237.8A patent/EP3985127A1/en active Pending
-
2022
- 2022-05-27 US US17/826,834 patent/US12331363B2/en active Active
- 2022-09-08 JP JP2022142901A patent/JP7441907B2/ja active Active
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