JP2020178590A5 - - Google Patents

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JP2020178590A5
JP2020178590A5 JP2019082640A JP2019082640A JP2020178590A5 JP 2020178590 A5 JP2020178590 A5 JP 2020178590A5 JP 2019082640 A JP2019082640 A JP 2019082640A JP 2019082640 A JP2019082640 A JP 2019082640A JP 2020178590 A5 JP2020178590 A5 JP 2020178590A5
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genotype
stones
urinary tract
kidney
data
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JP2019082640A
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JP7161443B2 (en
JP2020178590A (en
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尿管結石及び/又は腎結石に罹患したヒトの遺伝子型データと、尿管結石及び/又は腎結石に罹患していないヒトの遺伝子型データと、を学習データとして用いて機械学習したモデルを用いて、尿管結石及び/又は腎結石と正の相関があるrs174549、及びrs2009262と、尿管結石及び/又は腎結石と負の相関があるrs5955543、rs8176746、rs2280090、rs5945326、rs11175194、及びrs12688220を少なくとも含む一塩基多型セットの遺伝子型情報であって、 Using a machine-learned model using human genotype data with urinary tract stones and / or kidney stones and human genotype data without urinary tract stones and / or kidney stones as training data. At least rs174549 and rs2009262, which are positively correlated with urinary tract stones and / or kidney stones, and rs5955543, rs8176746, rs2280090, rs5945326, rs11175194, and rs12688220, which are negatively correlated with urinary tract stones and / or kidney stones. It is the genotype information of the one-base polymorphic set including
rs174549の遺伝子型がAG、rs2009262の遺伝子型がTC、rs5955543の遺伝子型がAG、rs8176746の遺伝子型がAC、rs2280090の遺伝子型がGG又はAG、rs5945326の遺伝子型がAA又はAG、rs11175194の遺伝子型がAG、及びrs12688220の遺伝子型がTCであるか否かに関する遺伝子型情報に基づいて、尿管結石及び/又は腎結石のリスクを判定する、方法。 rs174549 genotype AG, rs2009262 genotype TC, rs5955543 genotype AG, rs8176746 genotype AC, rs2280090 genotype GG or AG, rs5945326 genotype AA or AG, rs11175194 genotype A method of determining the risk of urinary tract stones and / or renal stones based on genotype information regarding whether the genotype of AG and rs12688220 is TC.
リスクの判定を受ける対象者の体液サンプル、細胞サンプル又は体毛を用いる、請求項1に記載の方法。The method according to claim 1, wherein a body fluid sample, a cell sample, or hair of a subject who receives a risk determination is used.
JP2019082640A 2019-04-24 2019-04-24 Method for determining the risk of ureteral and/or renal stones Active JP7161443B2 (en)

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JP2019082640A JP7161443B2 (en) 2019-04-24 2019-04-24 Method for determining the risk of ureteral and/or renal stones

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JP2019082640A JP7161443B2 (en) 2019-04-24 2019-04-24 Method for determining the risk of ureteral and/or renal stones

Publications (3)

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JP2020178590A JP2020178590A (en) 2020-11-05
JP2020178590A5 true JP2020178590A5 (en) 2022-03-18
JP7161443B2 JP7161443B2 (en) 2022-10-26

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JP2019082640A Active JP7161443B2 (en) 2019-04-24 2019-04-24 Method for determining the risk of ureteral and/or renal stones

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JP7306933B2 (en) 2018-09-21 2023-07-11 古河電気工業株式会社 Image determination device, image inspection device, and image determination method

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* Cited by examiner, † Cited by third party
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TWI555848B (en) * 2010-10-20 2016-11-01 高雄醫學大學 Method for estimating a risk of developing kidney stone in a subject, method for estimating a risk of recurring kidney stone in a subject suffering from or being used to suffer from kidney stone and use of snp rs12313273 (c/t) as a biomarker for developm
US20170002413A1 (en) * 2014-01-17 2017-01-05 The University Of Tokyo Molecule associated with onset of gout, and method and kit for evaluating diathesis of uric acid-related diseases and inflammation-related diseases, and inspection object and drug

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