JP2020096945A - 自動薬物送達装置 - Google Patents
自動薬物送達装置 Download PDFInfo
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- JP2020096945A JP2020096945A JP2020032323A JP2020032323A JP2020096945A JP 2020096945 A JP2020096945 A JP 2020096945A JP 2020032323 A JP2020032323 A JP 2020032323A JP 2020032323 A JP2020032323 A JP 2020032323A JP 2020096945 A JP2020096945 A JP 2020096945A
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- 238000012377 drug delivery Methods 0.000 title claims abstract description 45
- 239000003814 drug Substances 0.000 claims abstract description 249
- 229940079593 drug Drugs 0.000 claims abstract description 249
- 230000007246 mechanism Effects 0.000 claims abstract description 90
- 238000003780 insertion Methods 0.000 claims description 82
- 230000037431 insertion Effects 0.000 claims description 82
- 238000002347 injection Methods 0.000 claims description 41
- 239000007924 injection Substances 0.000 claims description 41
- 230000006835 compression Effects 0.000 claims description 25
- 238000007906 compression Methods 0.000 claims description 25
- 238000001647 drug administration Methods 0.000 abstract 1
- 238000007789 sealing Methods 0.000 description 43
- 230000009471 action Effects 0.000 description 10
- 238000010586 diagram Methods 0.000 description 10
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- 239000012530 fluid Substances 0.000 description 6
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- 230000004913 activation Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 239000011888 foil Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
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- 238000003860 storage Methods 0.000 description 2
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 description 1
- 206010073753 Fear of injection Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
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- 229940048921 humira Drugs 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
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- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
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- A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
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- A61M2005/2006—Having specific accessories
- A61M2005/202—Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
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- A61M2005/2474—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with movable piercing means, e.g. ampoule remains fixed or steady
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A61M5/178—Syringes
- A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
第1の解放メカニズムの動作前には、針の内部が薬物と接触しなくともよい。
Claims (13)
- 薬物送達装置であって、
薬物と、薬物容器アセンブリ内部に配置されたプランジャーとを収容し、前記薬物の投与のための出口を有し、初期位置においては前記出口が封止されている、薬物容器アセンブリと、
前記プランジャーまたは前記薬物容器に圧力を加えて前記薬物を加圧するよう構成される第1の蓄積エネルギー源を備える駆動メカニズムと、
前記薬物が加圧された後に前記出口を開封するよう構成される第1の解放メカニズムとを備え、
前記駆動メカニズムは第1のサブアセンブリを形成し、前記薬物容器と第1の解放メカニズムは第2のサブアセンブリを形成し、
前記第1のサブアセンブリが前記第2のサブアセンブリに接続されると前記第1の蓄積エネルギー源にエネルギーが蓄積されるよう構成される、薬物送達装置。 - 前記第1の蓄積エネルギー源を解放するよう構成される、または前記第1の蓄積エネルギー源内にエネルギーを蓄積して前記薬物を加圧するよう構成される第2の解放メカニズムをさらに備える、請求項1に記載の薬物送達装置。
- 前記第2の解放メカニズムは、キャップまたはカバーを前記装置から取り外すことによって動作する、請求項2に記載の薬物送達装置。
- 前記第2の解放メカニズムが動作するまでは、前記第1の解放メカニズムが動作することができないよう構成される、請求項2または請求項3に記載の薬物送達装置。
- 前記第1の蓄積エネルギー源は、前記第1のサブアセンブリが前記第2のサブアセンブリに接続されると圧縮される圧縮バネである、請求項1から請求項4のいずれか1項に記載の薬物送達装置。
- 前記第1のサブアセンブリは、ねじ込み継ぎ手または機械的なインターロック継ぎ手により前記第2のサブアセンブリに接続される、請求項1から請求項5のいずれか1項に記載の薬物送達装置。
- 前記第1のサブアセンブリは、前記第2のサブアセンブリから分離して別の第2のサブアセンブリと再利用可能なように構成される、請求項1から請求項6のいずれか1項に記載の薬物送達装置。
- 前記装置は、前記装置の薬物が送達される前端部が注射部位に押し付けられた時にのみ、前記第1の解放メカニズムが動作可能とするよう構成される、請求項1から請求項7のいずれか1項に記載の薬物送達装置。
- 使用時に前記薬物を送達する皮下注射針を備え、前記第1の解放メカニズムの動作前には、前記皮下注射針の内部が前記薬物と接触しない、請求項1から請求項8のいずれか1項に記載の薬物送達装置。
- 前記装置は、使用時に前記薬物を送達する皮下注射針を備え、前記皮下注射針を自動的に注射部位に挿入するよう構成される針挿入メカニズムを備える、請求項1から請求項9のいずれか1項に記載の薬物送達装置。
- 前記針挿入メカニズムは、前記第1の解放メカニズムによって解放される第2の蓄積エネルギー源を備える、請求項10に記載の薬物送達装置。
- 前記針挿入メカニズムは、針ハブおよび前記プランジャーが異なる軸に沿って移動するよう配置される、請求項11に記載の薬物送達装置。
- 前記薬物送達装置は自己注射器である、請求項1から請求項12のいずれか一項に記載の薬物送達装置。
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2021131725A JP7432561B2 (ja) | 2012-10-17 | 2021-08-12 | 自動薬物送達装置 |
JP2024016032A JP2024042084A (ja) | 2012-10-17 | 2024-02-05 | 自動薬物送達装置 |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1218667.2 | 2012-10-17 | ||
GBGB1218667.2A GB201218667D0 (en) | 2012-10-17 | 2012-10-17 | A drug delivery device with a moving needle assembly |
GB1303577.9 | 2013-02-28 | ||
GB201303577A GB201303577D0 (en) | 2013-02-28 | 2013-02-28 | Drug delivery device |
JP2018206423A JP6669838B2 (ja) | 2012-10-17 | 2018-11-01 | 自動薬物送達装置 |
Related Parent Applications (1)
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JP2018206423A Division JP6669838B2 (ja) | 2012-10-17 | 2018-11-01 | 自動薬物送達装置 |
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JP2020096945A true JP2020096945A (ja) | 2020-06-25 |
JP6931105B2 JP6931105B2 (ja) | 2021-09-01 |
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JP2015537271A Active JP6436397B2 (ja) | 2012-10-17 | 2013-10-17 | 自動薬物送達装置 |
JP2018206423A Active JP6669838B2 (ja) | 2012-10-17 | 2018-11-01 | 自動薬物送達装置 |
JP2020032323A Active JP6931105B2 (ja) | 2012-10-17 | 2020-02-27 | 自動薬物送達装置 |
JP2021131725A Active JP7432561B2 (ja) | 2012-10-17 | 2021-08-12 | 自動薬物送達装置 |
JP2024016032A Pending JP2024042084A (ja) | 2012-10-17 | 2024-02-05 | 自動薬物送達装置 |
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JP2015537271A Active JP6436397B2 (ja) | 2012-10-17 | 2013-10-17 | 自動薬物送達装置 |
JP2018206423A Active JP6669838B2 (ja) | 2012-10-17 | 2018-11-01 | 自動薬物送達装置 |
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JP2024016032A Pending JP2024042084A (ja) | 2012-10-17 | 2024-02-05 | 自動薬物送達装置 |
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US (3) | US10238804B2 (ja) |
EP (3) | EP3738627A1 (ja) |
JP (5) | JP6436397B2 (ja) |
CN (3) | CN104853787B (ja) |
WO (1) | WO2014060563A2 (ja) |
Families Citing this family (51)
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DK3184136T3 (da) | 2010-03-25 | 2021-08-23 | New Injection Systems Ltd | Injektor |
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US9522235B2 (en) | 2012-05-22 | 2016-12-20 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
EP2922588B1 (en) | 2012-11-23 | 2019-02-06 | New Injection Systems Ltd | Auto-injector assembly |
US10569017B2 (en) | 2013-03-15 | 2020-02-25 | Windgap Medical, Inc. | Portable drug mixing and delivery device and associated methods |
EP2968770B1 (en) | 2013-03-15 | 2020-12-30 | Windgap Medical, Inc. | Portable drug mixing and delivery system and method |
US9907910B2 (en) | 2013-03-15 | 2018-03-06 | Windgap Medical, Inc. | Portable drug mixing and delivery device and associated methods |
JP6256090B2 (ja) * | 2014-02-21 | 2018-01-10 | ティアック株式会社 | 可搬型電子機器 |
EP2923714A1 (en) * | 2014-03-28 | 2015-09-30 | Sanofi-Aventis Deutschland GmbH | Autoinjector triggered by skin contact |
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CN107106771B (zh) | 2014-08-18 | 2021-03-19 | 温德加普医疗股份有限公司 | 便携式药物混合和递送装置及相关方法 |
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CA2971440C (en) | 2014-12-18 | 2024-02-13 | Windgap Medical, Inc. | Method and compositions for dissolving or solubilizing therapeutic agents |
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EP3498322A1 (en) | 2019-06-19 |
WO2014060563A3 (en) | 2014-07-24 |
JP2019048099A (ja) | 2019-03-28 |
JP6931105B2 (ja) | 2021-09-01 |
US11324890B2 (en) | 2022-05-10 |
EP2908889A2 (en) | 2015-08-26 |
CN104853787A (zh) | 2015-08-19 |
CN113730703A (zh) | 2021-12-03 |
JP6436397B2 (ja) | 2018-12-12 |
WO2014060563A2 (en) | 2014-04-24 |
US20220233776A1 (en) | 2022-07-28 |
JP2024042084A (ja) | 2024-03-27 |
JP2015536162A (ja) | 2015-12-21 |
US20150283323A1 (en) | 2015-10-08 |
US20190151549A1 (en) | 2019-05-23 |
JP7432561B2 (ja) | 2024-02-16 |
EP3738627A1 (en) | 2020-11-18 |
CN108888836B (zh) | 2021-09-07 |
JP2021180911A (ja) | 2021-11-25 |
EP3498322B1 (en) | 2020-09-30 |
CN108888836A (zh) | 2018-11-27 |
US10238804B2 (en) | 2019-03-26 |
JP6669838B2 (ja) | 2020-03-18 |
EP2908889B1 (en) | 2018-09-05 |
CN104853787B (zh) | 2018-06-19 |
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