JP2020033265A - 皮膚外用剤 - Google Patents
皮膚外用剤 Download PDFInfo
- Publication number
- JP2020033265A JP2020033265A JP2018157940A JP2018157940A JP2020033265A JP 2020033265 A JP2020033265 A JP 2020033265A JP 2018157940 A JP2018157940 A JP 2018157940A JP 2018157940 A JP2018157940 A JP 2018157940A JP 2020033265 A JP2020033265 A JP 2020033265A
- Authority
- JP
- Japan
- Prior art keywords
- skin
- external preparation
- oil
- acid
- lecithin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 229930182558 Sterol Natural products 0.000 claims abstract description 15
- 235000003702 sterols Nutrition 0.000 claims abstract description 15
- -1 sterol esters Chemical class 0.000 claims abstract description 13
- 239000003240 coconut oil Substances 0.000 claims abstract description 12
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- 235000010445 lecithin Nutrition 0.000 claims abstract description 11
- 239000000787 lecithin Substances 0.000 claims abstract description 11
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- 150000004665 fatty acids Chemical class 0.000 description 22
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- 239000004475 Arginine Substances 0.000 description 2
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- 239000002253 acid Substances 0.000 description 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
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Images
Landscapes
- Cosmetics (AREA)
Abstract
Description
下記(A)〜(C)を含有する皮膚外用剤
(A)レシチン
(B)ヤシ油
(C)ステロールエステルから選択される1種又は2種以上
を提供する。
表1に示した組成の実施例並びに比較例を調製し、皮表角層水分量の測定を行った。
(1)馴化
被験者は前腕部を洗浄後、温度:21±0.5℃、湿度:50±5%にて調整された室内にて15分馴化することで初期条件を整え、塗布及び測定を行った。
前腕部3cm×3cmの領域にピペットを用いて9μL滴下し、指サックをした指で均一に塗布した。塗布してから30分後の皮表角層水分量の測定を行った。
SKICON-200EXを用いて、前腕部5点を測定し、平均値を皮表角層水分量とした。塗布前の皮表角層水分量を1とした場合の相対値を算出し、表1に示した。
(1)スクワラン 10.0(質量%)
(2)メチルフェニルポリシロキサン 4.0
(3)ヤシ油 0.5
(4)マカデミアナッツ油脂肪酸フィトステリル 0.5
(5)水素添加大豆レシチン 0.5
(6)モノステアリン酸ポリオキシエチレン
ソルビタン(20E.O.) 1.3
(7)モノステアリン酸ソルビタン 1.0
(8)グリセリン 4.0
(9)パラオキシ安息香酸メチル 0.1
(10)カルボキシビニルポリマー 0.15
(11)精製水 100合わせ
(12)アルギニン(1質量%水溶液) 20.0
製法:(1)〜(7)の油相成分を80℃にて加熱溶解する。一方(8)〜(11)の水相成分を80℃にて加熱溶解する。これに前記油相成分を攪拌しながら加え、ホモジナイザーにより均一に乳化する。乳化終了後、冷却を開始し、(12)を加え、均一に混合する。
(1)スクワラン 10.0(質量%)
(2)ステアリン酸 2.0
(3)ヤシ油 0.2
(4)マカデミアナッツ油脂肪酸フィトステリル 0.6
(5)水素添加大豆レシチン 0.5
(6)セタノール 3.6
(7)親油型モノステアリン酸グリセリン 2.0
(8)グリセリン 10.0
(9)パラオキシ安息香酸メチル 0.1
(10)アルギニン(20質量%水溶液) 15.0
(11)精製水 100合わせ
(12)カルボキシビニルポリマー(1質量%水溶液) 15.0
製法:(1)〜(7)の油相成分を80℃にて加熱溶解する。一方(8)〜(11)の水相成分を80℃にて加熱溶解する。これに前記油相成分を攪拌しながら加え、ホモジナイザーにより均一に乳化する。乳化終了後、(12)を加え、均一に混合する。
(1)精製水 100合わせ(質量%)
(2)グリセリン 10.0
(3)ショ糖脂肪酸エステル 1.3
(4)カルボキシビニルポリマー(1質量%水溶液) 17.5
(5)アルギン酸ナトリウム(1質量%水溶液) 15.0
(6)モノラウリン酸ポリグリセリル 1.0
(7)マカデミアナッツ油脂肪酸フィトステリル 3.0
(8)ヤシ油 2.0
(9)水素添加大豆レシチン 1.0
(10)硬化パーム油 2.0
(11)スクワラン(オリーブ由来) 1.0
(12)ベヘニルアルコール 0.75
(13)ミツロウ 1.0
(14)ホホバ油 1.0
(15)1、3−ブチレングリコール 10.0
(16)L−アルギニン(10質量%水溶液) 2.0
製法:(1)〜(6)の水相成分を混合し、75℃にて加熱溶解する。一方、(7)〜(15)の油相成分を混合し、75℃にて加熱溶解する。次いで、上記水相成分に油相成分を添加して予備乳化を行った後、ホモミキサーにて均一に乳化する。乳化終了後に冷却を開始し、50℃にて(16)を加え、均一に混合する。
Claims (1)
- 下記(A)〜(C)を含有する皮膚外用剤。
(A)レシチン
(B)ヤシ油
(C)ステロールエステルから選択される1種又は2種以上
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JP2018157940A JP2020033265A (ja) | 2018-08-27 | 2018-08-27 | 皮膚外用剤 |
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JP2020033265A true JP2020033265A (ja) | 2020-03-05 |
Family
ID=69666991
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JP2018157940A Pending JP2020033265A (ja) | 2018-08-27 | 2018-08-27 | 皮膚外用剤 |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012250916A (ja) * | 2011-05-31 | 2012-12-20 | Nippon Zettoc Co Ltd | 水中油型乳化化粧料 |
JP2015074646A (ja) * | 2013-10-11 | 2015-04-20 | 株式会社コーセー | 水中油型乳化化粧料 |
JP2018052823A (ja) * | 2016-09-26 | 2018-04-05 | 富士フイルム株式会社 | 水中油型乳化組成物 |
-
2018
- 2018-08-27 JP JP2018157940A patent/JP2020033265A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012250916A (ja) * | 2011-05-31 | 2012-12-20 | Nippon Zettoc Co Ltd | 水中油型乳化化粧料 |
JP2015074646A (ja) * | 2013-10-11 | 2015-04-20 | 株式会社コーセー | 水中油型乳化化粧料 |
JP2018052823A (ja) * | 2016-09-26 | 2018-04-05 | 富士フイルム株式会社 | 水中油型乳化組成物 |
Non-Patent Citations (4)
Title |
---|
COCONUT OIL MASK,ID 5660835 ,MINTEL GNPD[ONLINE],2018年5月,[検索日2021.11.04],URL,HTTPS://WWW.P, JPN6021044738, ISSN: 0004792062 * |
EMULSION ER,ID 5181013 ,MINTEL GNPD[ONLINE],2017年10月,[検索日2022.10.06],URL,HTTPS://WWW.PORTA, JPN6022043555, ISSN: 0004900101 * |
OIL AMPOULE,ID 5276995 ,MINTEL GNPD[ONLINE],2017年11月,[検索日2021.11.04],URL,HTTPS://WWW.PORTA, JPN6021044737, ISSN: 0004900102 * |
REPAIR EYE CREAM ,ID 4121685,MINTEL GNPD[ONLINE],2016年10月,[検索日2022.05.09],URL,HTTPS://WWW., JPN6022021421, ISSN: 0004900103 * |
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