JP2019535658A5 - - Google Patents
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- Publication number
- JP2019535658A5 JP2019535658A5 JP2019520591A JP2019520591A JP2019535658A5 JP 2019535658 A5 JP2019535658 A5 JP 2019535658A5 JP 2019520591 A JP2019520591 A JP 2019520591A JP 2019520591 A JP2019520591 A JP 2019520591A JP 2019535658 A5 JP2019535658 A5 JP 2019535658A5
- Authority
- JP
- Japan
- Prior art keywords
- benzo
- dimethyl
- imidazol
- piperidine
- difluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1617627.3A GB201617627D0 (en) | 2016-10-18 | 2016-10-18 | Pharmaceutical compounds |
| GB1617627.3 | 2016-10-18 | ||
| PCT/GB2017/053153 WO2018073587A1 (en) | 2016-10-18 | 2017-10-18 | Pharmaceutical compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019535658A JP2019535658A (ja) | 2019-12-12 |
| JP2019535658A5 true JP2019535658A5 (enExample) | 2020-11-26 |
| JP7082616B2 JP7082616B2 (ja) | 2022-06-08 |
Family
ID=57680679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019520591A Active JP7082616B2 (ja) | 2016-10-18 | 2017-10-18 | 医薬化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10647704B2 (enExample) |
| EP (1) | EP3529240B1 (enExample) |
| JP (1) | JP7082616B2 (enExample) |
| CN (1) | CN110036002B (enExample) |
| AU (1) | AU2017346454B2 (enExample) |
| DK (1) | DK3529240T3 (enExample) |
| ES (1) | ES2824814T3 (enExample) |
| GB (1) | GB201617627D0 (enExample) |
| HU (1) | HUE052107T2 (enExample) |
| WO (1) | WO2018073587A1 (enExample) |
| ZA (1) | ZA201902335B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201617630D0 (en) * | 2016-10-18 | 2016-11-30 | Cellcentric Ltd | Pharmaceutical compounds |
| TWI846350B (zh) | 2017-09-15 | 2024-06-21 | 美商佛瑪治療公司 | 作為ＣＢＰ／ｐ３００抑制劑之四氫－咪唑並喹啉化合物 |
| MX2023013508A (es) | 2018-06-29 | 2023-12-13 | Forma Therapeutics Inc | Inhibicion de la proteina de union a creb (cbp). |
| US12351577B2 (en) | 2019-03-15 | 2025-07-08 | Forma Therapeutics, Inc. | Inhibiting cyclic AMP-responsive element-binding protein (CREB) |
| CN112574189B (zh) * | 2019-09-27 | 2024-05-31 | 海创药业股份有限公司 | 一种ep300/cbp抑制剂 |
| CN112574191B (zh) * | 2019-09-29 | 2024-01-23 | 南京圣和药业股份有限公司 | 异噁唑杂环类化合物及其应用 |
| US11795168B2 (en) | 2020-09-23 | 2023-10-24 | Forma Therapeutics, Inc. | Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP) |
| US11801243B2 (en) | 2020-09-23 | 2023-10-31 | Forma Therapeutics, Inc. | Bromodomain inhibitors for androgen receptor-driven cancers |
| TW202227429A (zh) * | 2020-11-06 | 2022-07-16 | 大陸商貝達藥業股份有限公司 | Ｐ３００抑制劑、包含其的藥物組合物、其應用及製備其的方法 |
| US20240109879A1 (en) * | 2020-12-31 | 2024-04-04 | Medshine Discovery Inc. | Benzimidazole compound and application thereof |
| CN114989158A (zh) * | 2021-03-02 | 2022-09-02 | 复旦大学 | 组蛋白乙酰转移酶p300溴结构域抑制剂及其药用组合物及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200501960A (en) * | 2002-10-02 | 2005-01-16 | Bristol Myers Squibb Co | Synergistic kits and compositions for treating cancer |
| WO2007056593A2 (en) * | 2005-11-08 | 2007-05-18 | Choongwae Pharma Corporation | α-HELIX MIMETICS AND METHOD RELATING TO THE TREATMENT OF CANCER STEM CELLS |
| US8501957B2 (en) | 2008-12-10 | 2013-08-06 | China Medical University | Benzimidazole compounds and their use as anticancer agents |
| WO2011085039A2 (en) * | 2010-01-05 | 2011-07-14 | The Johns Hopkins University | Use of histone acetyltransferase inhibitors as novel anti-cancer therapies |
| EP2397471A1 (en) | 2010-06-16 | 2011-12-21 | China Medical University | Benzimidazole compounds and their use |
| TWI527811B (zh) | 2013-05-09 | 2016-04-01 | 吉李德科學股份有限公司 | 作爲溴結構域抑制劑的苯並咪唑衍生物 |
| WO2015004533A2 (en) * | 2013-06-21 | 2015-01-15 | Zenith Epigenetics Corp. | Novel substituted bicyclic compounds as bromodomain inhibitors |
| CN107531690B (zh) * | 2014-11-27 | 2020-11-06 | 基因泰克公司 | 用作CBP和/或EP300抑制剂的4,5,6,7-四氢-1H-吡唑并[4,3-c]吡啶-3-胺化合物 |
| CA2966452A1 (en) | 2014-12-17 | 2016-06-23 | Samuel David Brown | Substituted bicyclic compounds as bromodomain inhibitors |
| GB201506658D0 (en) * | 2015-04-20 | 2015-06-03 | Cellcentric Ltd | Pharmaceutical compounds |
| CA2994478C (en) | 2015-08-12 | 2023-10-03 | Neomed Institute | Substituted benzimidazoles, their preparation and their use as pharmaceuticals |
| GB201617630D0 (en) * | 2016-10-18 | 2016-11-30 | Cellcentric Ltd | Pharmaceutical compounds |
-
2016
- 2016-10-18 GB GBGB1617627.3A patent/GB201617627D0/en not_active Ceased
-
2017
- 2017-10-18 AU AU2017346454A patent/AU2017346454B2/en active Active
- 2017-10-18 DK DK17790814.2T patent/DK3529240T3/da active
- 2017-10-18 WO PCT/GB2017/053153 patent/WO2018073587A1/en not_active Ceased
- 2017-10-18 CN CN201780072397.7A patent/CN110036002B/zh active Active
- 2017-10-18 HU HUE17790814A patent/HUE052107T2/hu unknown
- 2017-10-18 JP JP2019520591A patent/JP7082616B2/ja active Active
- 2017-10-18 US US16/341,650 patent/US10647704B2/en active Active
- 2017-10-18 EP EP17790814.2A patent/EP3529240B1/en active Active
- 2017-10-18 ES ES17790814T patent/ES2824814T3/es active Active
-
2019
- 2019-04-12 ZA ZA2019/02335A patent/ZA201902335B/en unknown
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