JP2019534025A5 - - Google Patents

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Publication number
JP2019534025A5
JP2019534025A5 JP2019524385A JP2019524385A JP2019534025A5 JP 2019534025 A5 JP2019534025 A5 JP 2019534025A5 JP 2019524385 A JP2019524385 A JP 2019524385A JP 2019524385 A JP2019524385 A JP 2019524385A JP 2019534025 A5 JP2019534025 A5 JP 2019534025A5
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JP
Japan
Prior art keywords
nucleoside
oligonucleotide
region
capture probe
modified
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JP2019524385A
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English (en)
Japanese (ja)
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JP2019534025A (ja
JP7033591B2 (ja
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Priority claimed from PCT/EP2017/078695 external-priority patent/WO2018087200A1/en
Publication of JP2019534025A publication Critical patent/JP2019534025A/ja
Publication of JP2019534025A5 publication Critical patent/JP2019534025A5/ja
Application granted granted Critical
Publication of JP7033591B2 publication Critical patent/JP7033591B2/ja
Expired - Fee Related legal-status Critical Current
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JP2019524385A 2016-11-11 2017-11-09 治療用オリゴヌクレオチドの捕捉および検出 Expired - Fee Related JP7033591B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16198340.8 2016-11-11
EP16198340 2016-11-11
PCT/EP2017/078695 WO2018087200A1 (en) 2016-11-11 2017-11-09 Therapeutic oligonucleotides capture and detection

Publications (3)

Publication Number Publication Date
JP2019534025A JP2019534025A (ja) 2019-11-28
JP2019534025A5 true JP2019534025A5 (cg-RX-API-DMAC7.html) 2020-01-16
JP7033591B2 JP7033591B2 (ja) 2022-03-10

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JP2019524385A Expired - Fee Related JP7033591B2 (ja) 2016-11-11 2017-11-09 治療用オリゴヌクレオチドの捕捉および検出

Country Status (4)

Country Link
US (1) US20190284621A1 (cg-RX-API-DMAC7.html)
EP (1) EP3538671A1 (cg-RX-API-DMAC7.html)
JP (1) JP7033591B2 (cg-RX-API-DMAC7.html)
WO (1) WO2018087200A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019101298A (ru) 2016-07-01 2020-08-03 Ф. Хоффманн-Ля Рош Аг Антисмысловые олигонуклеотиды для модулирования экспрессии htra1
EP3568481A1 (en) * 2017-01-13 2019-11-20 Roche Innovation Center Copenhagen A/S Antisense oligonucleotides for modulating relb expression
US20190055564A1 (en) * 2017-06-01 2019-02-21 F. Hoffmann-La Roche Ag Antisense oligonucleotides for modulating htra1 expression
JP7754489B2 (ja) * 2019-11-14 2025-10-15 積水メディカル株式会社 オリゴヌクレオチドの検出又は定量方法
JP7620635B2 (ja) * 2020-01-16 2025-01-23 ディーエヌエイイー ダイアグノスティックス リミテッド 標的ポリヌクレオチドを単離するための組成物、キットおよび方法
WO2022099216A1 (en) * 2020-11-09 2022-05-12 Children's Medical Center Corporation Systems and methods for high throughput screening of molecular interactions
GB202217984D0 (en) * 2022-11-30 2023-01-11 Qbiotix Ltd Assays

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
JP4236812B2 (ja) 1997-09-12 2009-03-11 エクシコン エ/エス オリゴヌクレオチド類似体
ATE287897T2 (de) 1999-02-12 2005-02-15 Sankyo Co Analoga von nukleosiden und oligonukleotiden
CN102180924A (zh) 1999-05-04 2011-09-14 桑塔里斯制药公司 L-核糖-lna类似物
WO2001034845A1 (en) * 1999-11-12 2001-05-17 Isis Pharmaceuticals, Inc. Method for quantitating oligonucleotides
ATE442152T1 (de) 2002-11-18 2009-09-15 Santaris Pharma As Antisense-entwurf
JP4879975B2 (ja) * 2005-05-31 2012-02-22 アプライド バイオシステムズ リミテッド ライアビリティー カンパニー 短い核酸のマルチプレックス増幅
WO2007025281A2 (en) * 2005-08-24 2007-03-01 Applera Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
WO2007041201A2 (en) * 2005-10-03 2007-04-12 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
CN102908630B (zh) 2006-01-27 2014-11-19 Isis制药公司 6-修饰的双环核酸类似物
EP2066684B1 (en) 2006-05-11 2012-07-18 Isis Pharmaceuticals, Inc. 5'-modified bicyclic nucleic acid analogs
US7666854B2 (en) 2006-05-11 2010-02-23 Isis Pharmaceuticals, Inc. Bis-modified bicyclic nucleic acid analogs
EP1914317A1 (en) 2006-10-21 2008-04-23 Biolytix AG A method for qualitative and quantitative detection of short nucleic acid sequences of about 8 to 50 nucleotides in length
ES2388590T3 (es) 2007-05-30 2012-10-16 Isis Pharmaceuticals, Inc. Análogos de ácidos nucleicos bicíclicos con puente aminometileno N-sustituido.
WO2008154401A2 (en) 2007-06-08 2008-12-18 Isis Pharmaceuticals, Inc. Carbocyclic bicyclic nucleic acid analogs
WO2009006478A2 (en) 2007-07-05 2009-01-08 Isis Pharmaceuticals, Inc. 6-disubstituted bicyclic nucleic acid analogs
WO2009067647A1 (en) 2007-11-21 2009-05-28 Isis Pharmaceuticals, Inc. Carbocyclic alpha-l-bicyclic nucleic acid analogs
US8501805B2 (en) 2008-09-24 2013-08-06 Isis Pharmaceuticals, Inc. Substituted alpha-L-bicyclic nucleosides
EP2462153B1 (en) 2009-08-06 2015-07-29 Isis Pharmaceuticals, Inc. Bicyclic cyclohexose nucleic acid analogs
WO2011156202A1 (en) 2010-06-08 2011-12-15 Isis Pharmaceuticals, Inc. Substituted 2 '-amino and 2 '-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom
WO2013036868A1 (en) 2011-09-07 2013-03-14 Marina Biotech Inc. Synthesis and uses of nucleic acid compounds with conformationally restricted monomers
US10941396B2 (en) * 2012-02-27 2021-03-09 Becton, Dickinson And Company Compositions and kits for molecular counting
US9221864B2 (en) 2012-04-09 2015-12-29 Isis Pharmaceuticals, Inc. Tricyclic nucleic acid analogs
WO2013153911A1 (ja) * 2012-04-12 2013-10-17 国立大学法人東京大学 核酸の定量方法、検出プローブ、検出プローブセット、及び核酸の検出方法
US9816120B2 (en) * 2013-01-09 2017-11-14 The Penn State Research Foundation Low sequence bias single-stranded DNA ligation

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