JP2019533651A5 - - Google Patents
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- Publication number
- JP2019533651A5 JP2019533651A5 JP2019517236A JP2019517236A JP2019533651A5 JP 2019533651 A5 JP2019533651 A5 JP 2019533651A5 JP 2019517236 A JP2019517236 A JP 2019517236A JP 2019517236 A JP2019517236 A JP 2019517236A JP 2019533651 A5 JP2019533651 A5 JP 2019533651A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- subject
- administering
- effective amount
- therapeutically effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662405801P | 2016-10-07 | 2016-10-07 | |
| US62/405,801 | 2016-10-07 | ||
| US201762526331P | 2017-06-28 | 2017-06-28 | |
| US62/526,331 | 2017-06-28 | ||
| PCT/US2017/055660 WO2018068021A1 (en) | 2016-10-07 | 2017-10-06 | Inhibitors of glucocorticoid receptor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020191820A Division JP2021046409A (ja) | 2016-10-07 | 2020-11-18 | グルココルチコイド受容体の阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019533651A JP2019533651A (ja) | 2019-11-21 |
| JP2019533651A5 true JP2019533651A5 (OSRAM) | 2020-08-06 |
| JP6801093B2 JP6801093B2 (ja) | 2020-12-16 |
Family
ID=61832215
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517236A Active JP6801093B2 (ja) | 2016-10-07 | 2017-10-06 | グルココルチコイド受容体の阻害剤 |
| JP2020191820A Ceased JP2021046409A (ja) | 2016-10-07 | 2020-11-18 | グルココルチコイド受容体の阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020191820A Ceased JP2021046409A (ja) | 2016-10-07 | 2020-11-18 | グルココルチコイド受容体の阻害剤 |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US10472387B2 (OSRAM) |
| EP (2) | EP3851444A1 (OSRAM) |
| JP (2) | JP6801093B2 (OSRAM) |
| KR (2) | KR102237916B1 (OSRAM) |
| CN (2) | CN110099915A (OSRAM) |
| AU (3) | AU2017339510B2 (OSRAM) |
| BR (1) | BR112019006987B1 (OSRAM) |
| CA (1) | CA3039636C (OSRAM) |
| DK (1) | DK3523315T3 (OSRAM) |
| ES (1) | ES2867853T3 (OSRAM) |
| HU (1) | HUE054542T2 (OSRAM) |
| IL (2) | IL265835B (OSRAM) |
| MX (2) | MX385658B (OSRAM) |
| NZ (1) | NZ753142A (OSRAM) |
| PL (1) | PL3523315T3 (OSRAM) |
| PT (1) | PT3523315T (OSRAM) |
| SG (1) | SG11201903055UA (OSRAM) |
| SI (1) | SI3523315T1 (OSRAM) |
| WO (1) | WO2018068021A1 (OSRAM) |
| ZA (1) | ZA202004440B (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017112904A1 (en) | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| CN108699102A (zh) | 2015-12-23 | 2018-10-23 | 欧瑞克制药公司 | 糖皮质激素受体抑制剂 |
| CA3009525A1 (en) | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| SG11201903055UA (en) | 2016-10-07 | 2019-05-30 | Oric Pharmaceuticals Inc | Inhibitors of glucocorticoid receptor |
| CN112272552A (zh) * | 2018-04-11 | 2021-01-26 | 欧瑞克制药公司 | 包含糖皮质激素受体拮抗剂的固体形式和制剂及其用途 |
| WO2021163273A1 (en) * | 2020-02-12 | 2021-08-19 | Oric Pharmaceuticals, Inc. | Uses of glucocorticoid receptor antagonists |
| WO2021226465A1 (en) * | 2020-05-08 | 2021-11-11 | Trustees Of Dartmouth College | Glucocorticoid receptor modulators |
| CN115915529A (zh) | 2021-09-30 | 2023-04-04 | 赛万特科技有限责任公司 | 发光控制方法、发光控制装置及发光装置 |
| CN114230627B (zh) * | 2021-12-31 | 2023-09-15 | 湖南新合新生物医药有限公司 | 一种倍他米松环氧水解物中间体的制备方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| FR2528434B1 (fr) | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
| FR2522328B1 (fr) | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
| JP2785023B2 (ja) | 1987-12-30 | 1998-08-13 | ルセル―ユクラフ | １７α位置を置換された１７β―ＯＨ―１９―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物 |
| JPH02188599A (ja) | 1988-11-16 | 1990-07-24 | Roussel Uclaf | ３―ケト―デルタ―４，９―１９―ノルステロイドから誘導される新物質及びそれらよりなる薬剤 |
| DE3921059A1 (de) * | 1989-06-23 | 1991-01-10 | Schering Ag | 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel |
| FR2651435A1 (fr) | 1989-09-07 | 1991-03-08 | Roussel Uclaf | Nouvelle utilisation de composes anti-progestomimetiques. |
| DE4018167A1 (de) * | 1990-06-01 | 1991-12-05 | Schering Ag | Verfahren zur herstellung von 10(beta)-h-steroiden |
| DE4042007A1 (de) * | 1990-12-22 | 1992-06-25 | Schering Ag | 6,7-modifizierte-11(beta)-aryl-4-estrene |
| JP3828926B2 (ja) | 1993-08-04 | 2006-10-04 | アクゾ・ノベル・エヌ・ベー | 不安症の治療用抗グルココルチコイドステロイド |
| AU1439595A (en) | 1993-12-22 | 1995-07-10 | Salk Institute For Biological Studies, The | Methods for reducing multidrug resistance |
| MX9603889A (es) | 1995-02-02 | 1997-04-30 | Schering Ag | Antagonistas de progesterona para la produccion de agente farmaceuticos para el tratamiento de sangrado uterino disfuncional. |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| IL122740A (en) | 1997-01-15 | 2003-09-17 | Akzo Nobel Nv | 16-hydroxy-11-(substituted phenyl)-estra-9,4-diene derivatives, their preparation and pharmaceutical compositions containing them |
| CN1085078C (zh) * | 1998-01-07 | 2002-05-22 | 沈志华 | 用于大月份引产的复合药物 |
| US6512130B1 (en) * | 2000-09-05 | 2003-01-28 | Council Of Scientific And Industrial Research | Mifepristone analogue, process for the preparation thereof and use thereof |
| EP1285927A3 (de) * | 2001-08-16 | 2005-06-29 | Schering Aktiengesellschaft | Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems |
| US7250408B2 (en) * | 2002-12-16 | 2007-07-31 | Bayer Schering Pharma Ag | Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility |
| EP1989218B1 (en) | 2006-02-17 | 2009-12-30 | Janssen Pharmaceutica, N.V. | 17-phosphorous steroid derivatives useful as progesterone receptor modulators |
| CN101460467B (zh) | 2006-03-29 | 2012-09-19 | 加利福尼亚大学董事会 | 二芳基硫代乙内酰脲化合物 |
| CA2684450C (en) | 2007-04-20 | 2017-05-30 | Preglem S.A. | Progesterone antagonist and selective progesterone modulator in the treatment of excessive uterine bleeding |
| JP5804395B2 (ja) | 2011-02-03 | 2015-11-04 | ポップ テスト オンコロジー エルエルシー | 診断と治療のためのシステムおよび方法 |
| EP2545922A1 (en) | 2011-07-12 | 2013-01-16 | PregLem S.A. | Treatment of excessive menstrual bleeding associated with uterine fibroids |
| US20130029953A1 (en) | 2011-07-28 | 2013-01-31 | Klaus Nickisch | Progesterone antagonists |
| PL3912626T3 (pl) | 2012-02-24 | 2025-01-20 | The University Of Chicago | Sposoby i kompozycje dotyczące antagonizmu wobec receptora glukokortykoidowego i nowotworu prostaty |
| EP2641602A1 (en) | 2012-03-23 | 2013-09-25 | PregLem S.A. | Method for treating gynecological diseases |
| US9096641B2 (en) * | 2013-06-05 | 2015-08-04 | Evestra, Inc. | Imidazolyl progesterone antagonists |
| US10919929B2 (en) * | 2013-12-11 | 2021-02-16 | Sloan-Kettering Institute For Cancer Research | Glucocorticoid inhibitors for treatment of prostate cancer |
| CN104530166B (zh) | 2014-12-04 | 2016-08-24 | 陕西汉江药业集团股份有限公司 | 选择性还原4,6-共轭双烯-3-酮甾体化合物的方法 |
| CA3009525A1 (en) * | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| CN108699102A (zh) * | 2015-12-23 | 2018-10-23 | 欧瑞克制药公司 | 糖皮质激素受体抑制剂 |
| WO2017112904A1 (en) | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| SG11201903055UA (en) | 2016-10-07 | 2019-05-30 | Oric Pharmaceuticals Inc | Inhibitors of glucocorticoid receptor |
| US12233073B2 (en) | 2017-06-09 | 2025-02-25 | Regents Of The University Of Minnesota | Skin care formulations and skin cancer treatment |
| CN112272552A (zh) | 2018-04-11 | 2021-01-26 | 欧瑞克制药公司 | 包含糖皮质激素受体拮抗剂的固体形式和制剂及其用途 |
-
2017
- 2017-10-06 SG SG11201903055UA patent/SG11201903055UA/en unknown
- 2017-10-06 HU HUE17859300A patent/HUE054542T2/hu unknown
- 2017-10-06 BR BR112019006987-9A patent/BR112019006987B1/pt active IP Right Grant
- 2017-10-06 KR KR1020197013128A patent/KR102237916B1/ko active Active
- 2017-10-06 EP EP21158497.4A patent/EP3851444A1/en not_active Withdrawn
- 2017-10-06 PT PT178593000T patent/PT3523315T/pt unknown
- 2017-10-06 SI SI201730703T patent/SI3523315T1/sl unknown
- 2017-10-06 WO PCT/US2017/055660 patent/WO2018068021A1/en not_active Ceased
- 2017-10-06 DK DK17859300.0T patent/DK3523315T3/da active
- 2017-10-06 NZ NZ753142A patent/NZ753142A/en unknown
- 2017-10-06 ES ES17859300T patent/ES2867853T3/es active Active
- 2017-10-06 EP EP17859300.0A patent/EP3523315B1/en active Active
- 2017-10-06 AU AU2017339510A patent/AU2017339510B2/en active Active
- 2017-10-06 CN CN201780075818.1A patent/CN110099915A/zh active Pending
- 2017-10-06 PL PL17859300T patent/PL3523315T3/pl unknown
- 2017-10-06 JP JP2019517236A patent/JP6801093B2/ja active Active
- 2017-10-06 CN CN202010567003.9A patent/CN111690031B/zh active Active
- 2017-10-06 CA CA3039636A patent/CA3039636C/en active Active
- 2017-10-06 MX MX2019004030A patent/MX385658B/es unknown
- 2017-10-06 KR KR1020217009733A patent/KR20210039001A/ko not_active Ceased
-
2019
- 2019-03-26 US US16/365,422 patent/US10472387B2/en active Active
- 2019-04-04 IL IL265835A patent/IL265835B/en active IP Right Grant
- 2019-04-05 MX MX2021010252A patent/MX2021010252A/es unknown
- 2019-09-05 US US16/562,204 patent/US10723759B2/en active Active
-
2020
- 2020-06-01 US US16/889,624 patent/US10836789B2/en active Active
- 2020-07-20 ZA ZA2020/04440A patent/ZA202004440B/en unknown
- 2020-08-05 AU AU2020213316A patent/AU2020213316B2/en active Active
- 2020-09-30 US US17/039,794 patent/US20210017219A1/en not_active Abandoned
- 2020-11-18 JP JP2020191820A patent/JP2021046409A/ja not_active Ceased
-
2021
- 2021-03-31 AU AU2021202016A patent/AU2021202016C1/en active Active
- 2021-06-15 IL IL284005A patent/IL284005A/en unknown
-
2022
- 2022-08-15 US US17/887,777 patent/US20230096870A1/en not_active Abandoned
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