JP2019531286A - Ｃｈｓ−１３１による多発性硬化症の治療 - Google Patents

Ｃｈｓ−１３１による多発性硬化症の治療 Download PDF

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Publication number
JP2019531286A
JP2019531286A JP2019513922A JP2019513922A JP2019531286A JP 2019531286 A JP2019531286 A JP 2019531286A JP 2019513922 A JP2019513922 A JP 2019513922A JP 2019513922 A JP2019513922 A JP 2019513922A JP 2019531286 A JP2019531286 A JP 2019531286A
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effective amount
therapeutically effective
compound
multiple sclerosis
milligrams
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JP2019531286A5 (https=
Inventor
バルバラ フィンク
バルバラ フィンク
ロバート ジバディノフ
ロバート ジバディノフ
ホン タン
ホン タン
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インテクリン セラピューティクス インコーポレイテッド
インテクリン セラピューティクス インコーポレイテッド
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Publication of JP2019531286A publication Critical patent/JP2019531286A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2019513922A 2016-09-13 2017-09-13 Ｃｈｓ−１３１による多発性硬化症の治療 Pending JP2019531286A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662394046P 2016-09-13 2016-09-13
US62/394,046 2016-09-13
US201662436356P 2016-12-19 2016-12-19
US62/436,356 2016-12-19
US201762460868P 2017-02-19 2017-02-19
US62/460,868 2017-02-19
US201762491071P 2017-04-27 2017-04-27
US62/491,071 2017-04-27
PCT/US2017/051414 WO2018053040A1 (en) 2016-09-13 2017-09-13 Treatment of multiple sclerosis with chs-131

Publications (2)

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JP2019531286A true JP2019531286A (ja) 2019-10-31
JP2019531286A5 JP2019531286A5 (https=) 2020-10-22

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JP2019513922A Pending JP2019531286A (ja) 2016-09-13 2017-09-13 Ｃｈｓ−１３１による多発性硬化症の治療

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US (1) US20190224186A1 (https=)
EP (1) EP3512512A4 (https=)
JP (1) JP2019531286A (https=)
KR (1) KR20190064583A (https=)
CN (1) CN110461318A (https=)
AU (1) AU2017326261A1 (https=)
BR (1) BR112019004791A2 (https=)
CA (1) CA3036694A1 (https=)
IL (1) IL265259A (https=)
MX (1) MX2019002901A (https=)
SG (1) SG10202102198RA (https=)
WO (1) WO2018053040A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130158077A1 (en) 2011-12-19 2013-06-20 Ares Trading S.A. Pharmaceutical compositions
EA201791982A1 (ru) 2015-03-09 2020-02-17 Интекрин Терапьютикс, Инк. Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
JP2020515639A (ja) 2017-04-03 2020-05-28 コヒラス・バイオサイエンシズ・インコーポレイテッド 進行性核上性麻痺の処置のためのＰＰＡＲγアゴニスト
EA201992364A1 (ru) * 2018-04-02 2020-03-23 Кохерус Байосайенсис Инк. АГОНИСТ PPARγ ДЛЯ ЛЕЧЕНИЯ ПРОГРЕССИРУЮЩЕГО НАДЪЯДЕРНОГО ПАРАЛИЧА

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007507537A (ja) * 2003-10-03 2007-03-29 アムジェン インコーポレーテッド 強力な抗糖尿病薬化合物の塩および多形体
JP2016506956A (ja) * 2013-01-30 2016-03-07 インテクリン・セラピユーテイクス・インコーポレイテツド 多発性硬化症を治療するためのＰＰＡＲγアゴニスト

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112015007782A2 (pt) * 2012-10-12 2017-07-04 Teva Pharma laquinimod para reduzir danos talâmicos na esclerose múltipla

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007507537A (ja) * 2003-10-03 2007-03-29 アムジェン インコーポレーテッド 強力な抗糖尿病薬化合物の塩および多形体
JP2016506956A (ja) * 2013-01-30 2016-03-07 インテクリン・セラピユーテイクス・インコーポレイテツド 多発性硬化症を治療するためのＰＰＡＲγアゴニスト

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BRAIN, vol. 122, JPN6021025537, 1999, pages 871 - 882, ISSN: 0004870728 *
CLINICALTRIALS.GOV ARCHIVE NCT02638038 ON 2015_12_20, ２０１５年１２月２０日，RETRIEVED FROM THE INT, JPN6021025539, 20 December 2015 (2015-12-20), ISSN: 0004870727 *
甲南女子大学研究紀要第２号 看護学・リハビリテーション学編, JPN6022014978, 2009, pages 107 - 112, ISSN: 0004870729 *

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Publication number Publication date
BR112019004791A2 (pt) 2019-06-04
CA3036694A1 (en) 2018-03-22
EP3512512A4 (en) 2020-06-03
WO2018053040A1 (en) 2018-03-22
CN110461318A (zh) 2019-11-15
SG10202102198RA (en) 2021-04-29
IL265259A (en) 2019-05-30
US20190224186A1 (en) 2019-07-25
MX2019002901A (es) 2019-09-26
EP3512512A1 (en) 2019-07-24
KR20190064583A (ko) 2019-06-10
AU2017326261A1 (en) 2019-04-04

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