JP2019524168A5 - - Google Patents
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- Publication number
- JP2019524168A5 JP2019524168A5 JP2018556832A JP2018556832A JP2019524168A5 JP 2019524168 A5 JP2019524168 A5 JP 2019524168A5 JP 2018556832 A JP2018556832 A JP 2018556832A JP 2018556832 A JP2018556832 A JP 2018556832A JP 2019524168 A5 JP2019524168 A5 JP 2019524168A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- ablation
- intensity
- catheter
- fad
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001519 tissue Anatomy 0.000 description 40
- 238000002679 ablation Methods 0.000 description 32
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 description 21
- 235000019162 flavin adenine dinucleotide Nutrition 0.000 description 21
- 239000011714 flavin adenine dinucleotide Substances 0.000 description 21
- 229940093632 flavin-adenine dinucleotide Drugs 0.000 description 21
- 230000006378 damage Effects 0.000 description 17
- 230000015572 biosynthetic process Effects 0.000 description 14
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 12
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 11
- 208000027418 Wounds and injury Diseases 0.000 description 10
- 208000014674 injury Diseases 0.000 description 10
- 210000005003 heart tissue Anatomy 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 238000013507 mapping Methods 0.000 description 7
- 230000008859 change Effects 0.000 description 6
- 230000004044 response Effects 0.000 description 5
- 239000013307 optical fiber Substances 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 206010028851 Necrosis Diseases 0.000 description 3
- 238000013153 catheter ablation Methods 0.000 description 3
- 230000030833 cell death Effects 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 210000003470 mitochondria Anatomy 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000017074 necrotic cell death Effects 0.000 description 3
- YPZRHBJKEMOYQH-UYBVJOGSSA-L FADH2(2-) Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1COP([O-])(=O)OP([O-])(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C(NC(=O)NC2=O)=C2NC2=C1C=C(C)C(C)=C2 YPZRHBJKEMOYQH-UYBVJOGSSA-L 0.000 description 2
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 238000010317 ablation therapy Methods 0.000 description 1
- 238000011298 ablation treatment Methods 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000005061 intracellular organelle Anatomy 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 210000001700 mitochondrial membrane Anatomy 0.000 description 1
- 229950006238 nadide Drugs 0.000 description 1
- 229940101270 nicotinamide adenine dinucleotide (nad) Drugs 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662348901P | 2016-06-11 | 2016-06-11 | |
| US62/348,901 | 2016-06-11 | ||
| PCT/US2017/036905 WO2017214599A1 (en) | 2016-06-11 | 2017-06-09 | Systems and methods for monitoring tissue ablation using tissue autofluorescence |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524168A JP2019524168A (ja) | 2019-09-05 |
| JP2019524168A5 true JP2019524168A5 (https=) | 2020-05-28 |
| JP6724163B2 JP6724163B2 (ja) | 2020-07-15 |
Family
ID=59093627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018556832A Active JP6724163B2 (ja) | 2016-06-11 | 2017-06-09 | 組織の自己蛍光を使用した組織アブレーションの監視のためのシステム及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170354357A1 (https=) |
| EP (1) | EP3468448A1 (https=) |
| JP (1) | JP6724163B2 (https=) |
| CN (1) | CN109310333A (https=) |
| WO (1) | WO2017214599A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE112019006944T5 (de) | 2019-02-28 | 2021-12-02 | Olympus Corporation | Medizinisches System |
| CN111772772B (zh) * | 2020-06-12 | 2022-04-08 | 成都市第三人民医院 | 射频消融控制系统 |
| CN116249504B (zh) * | 2020-09-29 | 2025-11-28 | 奥林巴斯株式会社 | 辅助装置、内窥镜系统、辅助方法以及存储介质 |
| EP4289380B1 (en) * | 2022-06-09 | 2025-03-05 | Medlumics S.L. | Improving accuracy of ablation model through synchronization |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3283128B2 (ja) * | 1993-12-03 | 2002-05-20 | オリンパス光学工業株式会社 | 蛍光観察内視鏡装置 |
| US20030135122A1 (en) * | 1997-12-12 | 2003-07-17 | Spectrx, Inc. | Multi-modal optical tissue diagnostic system |
| AU2001251134B2 (en) * | 2000-03-31 | 2006-02-02 | Angiodynamics, Inc. | Tissue biopsy and treatment apparatus and method |
| US6706004B2 (en) * | 2001-05-31 | 2004-03-16 | Infraredx, Inc. | Balloon catheter |
| US7282723B2 (en) * | 2002-07-09 | 2007-10-16 | Medispectra, Inc. | Methods and apparatus for processing spectral data for use in tissue characterization |
| US20040064053A1 (en) * | 2002-09-30 | 2004-04-01 | Chang Sung K. | Diagnostic fluorescence and reflectance |
| JP4152402B2 (ja) * | 2005-06-29 | 2008-09-17 | 株式会社日立メディコ | 手術支援装置 |
| JP2008061858A (ja) * | 2006-09-08 | 2008-03-21 | Toshiba Corp | 穿刺治療ナビゲーション装置 |
| US9125562B2 (en) * | 2009-07-01 | 2015-09-08 | Avinger, Inc. | Catheter-based off-axis optical coherence tomography imaging system |
| CA2784576C (en) * | 2009-12-15 | 2020-01-07 | Emory University | System and methods for providing real-time anatomical guidance in a diagnostic or therapeutic procedure |
| CN104066368B (zh) * | 2011-09-22 | 2017-02-22 | 乔治华盛顿大学 | 用于使经消融组织可视化的系统和方法 |
| US11717165B2 (en) * | 2011-11-07 | 2023-08-08 | Koninklijke Philips N.V. | Detection apparatus for determining a state of tissue |
| JP6232044B2 (ja) * | 2012-03-23 | 2017-11-15 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 針変位速度に基づかれる測定集積時間を用いるフォトニック針システム |
| JP6737705B2 (ja) * | 2013-11-14 | 2020-08-12 | ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ | 損傷部位の深さを決定するシステムの動作方法及び心臓組織の画像を生成するシステム |
| JP6188612B2 (ja) * | 2014-03-26 | 2017-08-30 | 株式会社デンソー | 情報統合装置、情報統合システム、及びプログラム |
| JP6635363B2 (ja) * | 2014-10-24 | 2020-01-22 | 京都府公立大学法人 | 腫瘍部位の判別のための方法、腫瘍部位の判別装置 |
| EP3215002B1 (en) * | 2014-11-03 | 2024-03-20 | The George Washington University | Systems for lesion assessment |
| AU2015353464B2 (en) * | 2014-11-25 | 2020-07-16 | 460Medical, Inc. | Visualization catheters |
-
2017
- 2017-06-09 WO PCT/US2017/036905 patent/WO2017214599A1/en not_active Ceased
- 2017-06-09 US US15/619,410 patent/US20170354357A1/en not_active Abandoned
- 2017-06-09 EP EP17731985.2A patent/EP3468448A1/en not_active Withdrawn
- 2017-06-09 CN CN201780035876.1A patent/CN109310333A/zh active Pending
- 2017-06-09 JP JP2018556832A patent/JP6724163B2/ja active Active
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