JP2019524168A5 - - Google Patents
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- Publication number
- JP2019524168A5 JP2019524168A5 JP2018556832A JP2018556832A JP2019524168A5 JP 2019524168 A5 JP2019524168 A5 JP 2019524168A5 JP 2018556832 A JP2018556832 A JP 2018556832A JP 2018556832 A JP2018556832 A JP 2018556832A JP 2019524168 A5 JP2019524168 A5 JP 2019524168A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- ablation
- intensity
- catheter
- fad
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001519 tissue Anatomy 0.000 description 40
- 238000002679 ablation Methods 0.000 description 32
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 description 21
- 235000019162 flavin adenine dinucleotide Nutrition 0.000 description 21
- 239000011714 flavin adenine dinucleotide Substances 0.000 description 21
- 229940093632 flavin-adenine dinucleotide Drugs 0.000 description 21
- 230000006378 damage Effects 0.000 description 17
- 230000015572 biosynthetic process Effects 0.000 description 14
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 12
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 11
- 208000027418 Wounds and injury Diseases 0.000 description 10
- 208000014674 injury Diseases 0.000 description 10
- 210000005003 heart tissue Anatomy 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 238000013507 mapping Methods 0.000 description 7
- 230000008859 change Effects 0.000 description 6
- 230000004044 response Effects 0.000 description 5
- 239000013307 optical fiber Substances 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 206010028851 Necrosis Diseases 0.000 description 3
- 238000013153 catheter ablation Methods 0.000 description 3
- 230000030833 cell death Effects 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 210000003470 mitochondria Anatomy 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000017074 necrotic cell death Effects 0.000 description 3
- YPZRHBJKEMOYQH-UYBVJOGSSA-L FADH2(2-) Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1COP([O-])(=O)OP([O-])(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C(NC(=O)NC2=O)=C2NC2=C1C=C(C)C(C)=C2 YPZRHBJKEMOYQH-UYBVJOGSSA-L 0.000 description 2
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- 238000010317 ablation therapy Methods 0.000 description 1
- 238000011298 ablation treatment Methods 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000005061 intracellular organelle Anatomy 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 210000001700 mitochondrial membrane Anatomy 0.000 description 1
- 229950006238 nadide Drugs 0.000 description 1
- 229940101270 nicotinamide adenine dinucleotide (nad) Drugs 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662348901P | 2016-06-11 | 2016-06-11 | |
| US62/348,901 | 2016-06-11 | ||
| PCT/US2017/036905 WO2017214599A1 (en) | 2016-06-11 | 2017-06-09 | Systems and methods for monitoring tissue ablation using tissue autofluorescence |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019524168A JP2019524168A (ja) | 2019-09-05 |
| JP2019524168A5 true JP2019524168A5 (enExample) | 2020-05-28 |
| JP6724163B2 JP6724163B2 (ja) | 2020-07-15 |
Family
ID=59093627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018556832A Active JP6724163B2 (ja) | 2016-06-11 | 2017-06-09 | 組織の自己蛍光を使用した組織アブレーションの監視のためのシステム及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170354357A1 (enExample) |
| EP (1) | EP3468448A1 (enExample) |
| JP (1) | JP6724163B2 (enExample) |
| CN (1) | CN109310333A (enExample) |
| WO (1) | WO2017214599A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE112019006944T5 (de) * | 2019-02-28 | 2021-12-02 | Olympus Corporation | Medizinisches System |
| CN111772772B (zh) * | 2020-06-12 | 2022-04-08 | 成都市第三人民医院 | 射频消融控制系统 |
| EP4289380B1 (en) * | 2022-06-09 | 2025-03-05 | Medlumics S.L. | Improving accuracy of ablation model through synchronization |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3283128B2 (ja) * | 1993-12-03 | 2002-05-20 | オリンパス光学工業株式会社 | 蛍光観察内視鏡装置 |
| US20030135122A1 (en) * | 1997-12-12 | 2003-07-17 | Spectrx, Inc. | Multi-modal optical tissue diagnostic system |
| AU2001251134B2 (en) * | 2000-03-31 | 2006-02-02 | Angiodynamics, Inc. | Tissue biopsy and treatment apparatus and method |
| US6706004B2 (en) * | 2001-05-31 | 2004-03-16 | Infraredx, Inc. | Balloon catheter |
| US7282723B2 (en) * | 2002-07-09 | 2007-10-16 | Medispectra, Inc. | Methods and apparatus for processing spectral data for use in tissue characterization |
| US20040064053A1 (en) * | 2002-09-30 | 2004-04-01 | Chang Sung K. | Diagnostic fluorescence and reflectance |
| JP4152402B2 (ja) * | 2005-06-29 | 2008-09-17 | 株式会社日立メディコ | 手術支援装置 |
| JP2008061858A (ja) * | 2006-09-08 | 2008-03-21 | Toshiba Corp | 穿刺治療ナビゲーション装置 |
| US9125562B2 (en) * | 2009-07-01 | 2015-09-08 | Avinger, Inc. | Catheter-based off-axis optical coherence tomography imaging system |
| AU2010339972B2 (en) * | 2009-12-15 | 2015-04-30 | Emory University | System and method for providing real-time anatomical guidance in a diagnostic or therapeutic procedure |
| WO2013044182A1 (en) * | 2011-09-22 | 2013-03-28 | The George Washington University | Systems and methods for visualizing ablated tissue |
| CN103917155B (zh) * | 2011-11-07 | 2017-02-15 | 皇家飞利浦有限公司 | 用于确定组织状态的检测装置 |
| EP2827792B1 (en) * | 2012-03-23 | 2017-05-10 | Koninklijke Philips N.V. | Photonic needle system with selectable measurement integration times |
| WO2015073871A2 (en) * | 2013-11-14 | 2015-05-21 | The George Washington University | Systems and methods for determining lesion depth using fluorescence imaging |
| JP6188612B2 (ja) * | 2014-03-26 | 2017-08-30 | 株式会社デンソー | 情報統合装置、情報統合システム、及びプログラム |
| JP6635363B2 (ja) * | 2014-10-24 | 2020-01-22 | 京都府公立大学法人 | 腫瘍部位の判別のための方法、腫瘍部位の判別装置 |
| JP2017537681A (ja) * | 2014-11-03 | 2017-12-21 | ザ・ジョージ・ワシントン・ユニバーシティＴｈｅ Ｇｅｏｒｇｅ Ｗａｓｈｉｎｇｔｏｎｕｎｉｖｅｒｓｉｔｙ | 損傷評価システム及びその方法 |
| WO2016086160A1 (en) * | 2014-11-25 | 2016-06-02 | LuxCath, LLC | Visualization catheters |
-
2017
- 2017-06-09 CN CN201780035876.1A patent/CN109310333A/zh active Pending
- 2017-06-09 US US15/619,410 patent/US20170354357A1/en not_active Abandoned
- 2017-06-09 EP EP17731985.2A patent/EP3468448A1/en not_active Withdrawn
- 2017-06-09 JP JP2018556832A patent/JP6724163B2/ja active Active
- 2017-06-09 WO PCT/US2017/036905 patent/WO2017214599A1/en not_active Ceased
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