JP2019517540A - アルツハイマー病を治療する方法 - Google Patents

アルツハイマー病を治療する方法 Download PDF

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Publication number
JP2019517540A
JP2019517540A JP2018563815A JP2018563815A JP2019517540A JP 2019517540 A JP2019517540 A JP 2019517540A JP 2018563815 A JP2018563815 A JP 2018563815A JP 2018563815 A JP2018563815 A JP 2018563815A JP 2019517540 A JP2019517540 A JP 2019517540A
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antibody
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weeks
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Japanese (ja)
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JP2019517540A5 (cg-RX-API-DMAC7.html
Inventor
ブレンドン フィリップ ブート，
ブレンドン フィリップ ブート，
ジェフリー ジョセフ セヴィニー，
ジェフリー ジョセフ セヴィニー，
レスリー ルジーン ウイリアムズ，
レスリー ルジーン ウイリアムズ，
Original Assignee
バイオジェン インターナショナル ニューロサイエンス ゲーエムベーハー
バイオジェン インターナショナル ニューロサイエンス ゲーエムベーハー
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Publication of JP2019517540A publication Critical patent/JP2019517540A/ja
Publication of JP2019517540A5 publication Critical patent/JP2019517540A5/ja
Priority to JP2022129326A priority Critical patent/JP2022145965A/ja
Priority to JP2025124966A priority patent/JP2025160337A/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515—Complete light chain, i.e. VL + CL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2018563815A 2016-06-07 2017-06-06 アルツハイマー病を治療する方法 Withdrawn JP2019517540A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022129326A JP2022145965A (ja) 2016-06-07 2022-08-15 アルツハイマー病を治療する方法
JP2025124966A JP2025160337A (ja) 2016-06-07 2025-07-25 アルツハイマー病を治療する方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662346818P 2016-06-07 2016-06-07
US62/346,818 2016-06-07
US201662435531P 2016-12-16 2016-12-16
US62/435,531 2016-12-16
PCT/EP2017/063711 WO2017211827A1 (en) 2016-06-07 2017-06-06 Methods for treating alzheimer's disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022129326A Division JP2022145965A (ja) 2016-06-07 2022-08-15 アルツハイマー病を治療する方法

Publications (2)

Publication Number Publication Date
JP2019517540A true JP2019517540A (ja) 2019-06-24
JP2019517540A5 JP2019517540A5 (cg-RX-API-DMAC7.html) 2020-07-09

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2018563815A Withdrawn JP2019517540A (ja) 2016-06-07 2017-06-06 アルツハイマー病を治療する方法
JP2022129326A Withdrawn JP2022145965A (ja) 2016-06-07 2022-08-15 アルツハイマー病を治療する方法
JP2025124966A Pending JP2025160337A (ja) 2016-06-07 2025-07-25 アルツハイマー病を治療する方法

Family Applications After (2)

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JP2022129326A Withdrawn JP2022145965A (ja) 2016-06-07 2022-08-15 アルツハイマー病を治療する方法
JP2025124966A Pending JP2025160337A (ja) 2016-06-07 2025-07-25 アルツハイマー病を治療する方法

Country Status (12)

Country Link
US (2) US20200308259A1 (cg-RX-API-DMAC7.html)
EP (1) EP3464350A1 (cg-RX-API-DMAC7.html)
JP (3) JP2019517540A (cg-RX-API-DMAC7.html)
KR (2) KR20190021311A (cg-RX-API-DMAC7.html)
CN (3) CN114796481A (cg-RX-API-DMAC7.html)
AU (2) AU2017276656A1 (cg-RX-API-DMAC7.html)
BR (1) BR112018075300A2 (cg-RX-API-DMAC7.html)
CA (1) CA3026598A1 (cg-RX-API-DMAC7.html)
IL (1) IL263433B2 (cg-RX-API-DMAC7.html)
MA (1) MA45149A (cg-RX-API-DMAC7.html)
MX (1) MX2018015022A (cg-RX-API-DMAC7.html)
WO (1) WO2017211827A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022553329A (ja) * 2019-10-22 2022-12-22 バイオジェン・エムエイ・インコーポレイテッド アルツハイマー病を治療するための抗ベータ－アミロイド抗体

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* Cited by examiner, † Cited by third party
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TW201827467A (zh) 2016-11-03 2018-08-01 比利時商健生藥品公司 焦穀胺酸類澱粉蛋白－β之抗體及其用途
EP3696192A1 (en) 2019-02-15 2020-08-19 Consejo Superior De Investigaciones Científicas Therapeutic target and monoclonal antibodies against it for the diagnosis and treatment of alzheimer´s disease
CA3134785A1 (en) 2019-03-26 2020-10-01 Janssen Pharmaceutica Nv Antibodies to pyroglutamate amyloid-.beta. and uses thereof
CN110511276A (zh) * 2019-08-13 2019-11-29 王跃驹 植物作为宿主在表达Aducanumab抗体中的应用
UY39337A (es) 2020-07-23 2022-02-25 Othair Prothena Ltd Anticuerpos anti-abeta
KR102321601B1 (ko) * 2020-11-19 2021-11-05 주식회사 휴런 뇌 영상을 이용한 알츠하이머병의 생물학적 분류 장치 및 방법
US20240270830A1 (en) * 2021-06-07 2024-08-15 Biogen Ma Inc. Methods for treating alzheimer's disease
US20250122146A1 (en) * 2021-09-30 2025-04-17 The Scripps Research Institute Compounds for reducing neuroinflammation
KR20240101629A (ko) * 2021-11-19 2024-07-02 에이피 바이오사이언시스, 아이엔씨. Cd137을 표적화하는 이중특이적 항체 및 항암 면역요법을 위한 이의 용도

Citations (1)

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WO2015120233A1 (en) * 2014-02-08 2015-08-13 Genentech, Inc. Methods of treating alzheimer's disease

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KR20180043854A (ko) * 2006-07-14 2018-04-30 에이씨 이뮨 에스.에이. 아밀로이드 베타에 대해 인간화된 항체
SI2436696T1 (sl) 2007-01-05 2017-10-30 University Of Zurich Anti-beta-amiloidno protitelo in načini njegove uporabe
PT2627672T (pt) 2010-10-11 2018-11-16 Univ Zuerich Anticorpos anti-tau humanos
RS60388B1 (sr) * 2012-10-15 2020-07-31 Medimmune Ltd Antitela usmerena na beta-amiloid
WO2014089500A1 (en) * 2012-12-07 2014-06-12 Biogen Idec International Neuroscience Gmbh A METHOD OF REDUCING BRAIN AMYLOID PLAQUES USING ANTI-Aß ANTIBODIES
AU2013361107B2 (en) 2012-12-21 2018-08-23 Biogen International Neuroscience Gmbh Human anti-tau antibodies
MA41115A (fr) * 2014-12-02 2017-10-10 Biogen Int Neuroscience Gmbh Procédé de traitement de la maladie d'alzheimer

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Publication number Priority date Publication date Assignee Title
WO2015120233A1 (en) * 2014-02-08 2015-08-13 Genentech, Inc. Methods of treating alzheimer's disease

Non-Patent Citations (3)

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Title
ALZHEIMER'S & DEMENTIA, vol. 9, JPN6021020509, 2013, pages 105 - 115, ISSN: 0004888985 *
JACOPO C DIFRANCESCO: "ANTI-Aβ AUTOANTIBODIES IN AMYLOID RELATED IMAGING ABNORMALITIES (ARIA): CANDIDATE 以下備考", FRONTIERS IN NEUROLOGY, vol. 6, JPN5019005383, 25 September 2015 (2015-09-25), pages 1 - 6, ISSN: 0004888984 *
鹿児島市医報, vol. 第51巻, 第6号, JPN6022014696, 2012, pages 8 - 9, ISSN: 0004888986 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022553329A (ja) * 2019-10-22 2022-12-22 バイオジェン・エムエイ・インコーポレイテッド アルツハイマー病を治療するための抗ベータ－アミロイド抗体

Also Published As

Publication number Publication date
AU2024216442A1 (en) 2024-10-17
JP2025160337A (ja) 2025-10-22
IL263433B2 (en) 2024-03-01
CN114796481A (zh) 2022-07-29
US20200308259A1 (en) 2020-10-01
EP3464350A1 (en) 2019-04-10
US20220281963A1 (en) 2022-09-08
MX2018015022A (es) 2019-08-14
MA45149A (fr) 2019-04-10
JP2022145965A (ja) 2022-10-04
CA3026598A1 (en) 2017-12-14
CN109476730A (zh) 2019-03-15
BR112018075300A2 (pt) 2019-04-30
IL263433B1 (en) 2023-11-01
AU2017276656A1 (en) 2018-12-13
CN114931635A (zh) 2022-08-23
WO2017211827A1 (en) 2017-12-14
KR20230165883A (ko) 2023-12-05
IL263433A (en) 2019-01-31
KR20190021311A (ko) 2019-03-05

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