JP2019515672A5 - - Google Patents
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- JP2019515672A5 JP2019515672A5 JP2018554677A JP2018554677A JP2019515672A5 JP 2019515672 A5 JP2019515672 A5 JP 2019515672A5 JP 2018554677 A JP2018554677 A JP 2018554677A JP 2018554677 A JP2018554677 A JP 2018554677A JP 2019515672 A5 JP2019515672 A5 JP 2019515672A5
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022139098A JP2022164858A (ja) | 2016-04-20 | 2022-09-01 | 免疫調整性ｉｌ２ｒ融合タンパク質およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662325428P | 2016-04-20 | 2016-04-20 | |
| US62/325,428 | 2016-04-20 | ||
| PCT/US2017/028693 WO2017184901A1 (en) | 2016-04-20 | 2017-04-20 | Immunomodulatory il2r fusion proteins and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022139098A Division JP2022164858A (ja) | 2016-04-20 | 2022-09-01 | 免疫調整性ｉｌ２ｒ融合タンパク質およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019515672A JP2019515672A (ja) | 2019-06-13 |
| JP2019515672A5 true JP2019515672A5 (enExample) | 2020-05-28 |
| JP7198670B2 JP7198670B2 (ja) | 2023-01-04 |
Family
ID=58710057
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018554677A Active JP7198670B2 (ja) | 2016-04-20 | 2017-04-20 | 免疫調整性ｉｌ２ｒ融合タンパク質およびその使用 |
| JP2022139098A Ceased JP2022164858A (ja) | 2016-04-20 | 2022-09-01 | 免疫調整性ｉｌ２ｒ融合タンパク質およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022139098A Ceased JP2022164858A (ja) | 2016-04-20 | 2022-09-01 | 免疫調整性ｉｌ２ｒ融合タンパク質およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20190127435A1 (enExample) |
| EP (1) | EP3445847B1 (enExample) |
| JP (2) | JP7198670B2 (enExample) |
| CN (1) | CN109312304A (enExample) |
| CA (1) | CA3021455A1 (enExample) |
| ES (1) | ES2981274T3 (enExample) |
| WO (1) | WO2017184901A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1246317A1 (zh) | 2015-03-05 | 2018-09-07 | Fred Hutchinson Cancer Center | 免疫调节融合蛋白及其用途 |
| CN109689694B (zh) * | 2016-05-19 | 2022-11-22 | 通用医疗公司 | 与其受体IL-2Rβ结合的IL2作为用来增强自然杀伤细胞和调节性T细胞活性的平台 |
| JP2020511136A (ja) * | 2017-03-17 | 2020-04-16 | フレッド ハッチンソン キャンサー リサーチ センター | 免疫調節性融合タンパク質およびその使用 |
| WO2019052562A1 (zh) * | 2017-09-15 | 2019-03-21 | 科济生物医药（上海）有限公司 | Il-4r的融合蛋白及其应用 |
| CN108504685A (zh) * | 2018-03-27 | 2018-09-07 | 宜明细胞生物科技有限公司 | 一种利用CRISPR/Cas9系统同源重组修复IL-2RG缺陷基因的方法 |
| CN110615843B (zh) * | 2018-06-20 | 2023-05-09 | 上海隆耀生物科技有限公司 | 一种包含第三信号受体的嵌合抗原受体及其应用 |
| CA3097443A1 (en) * | 2018-11-12 | 2020-05-22 | I-Mab Biopharma Us Limited | Fusion proteins containing cd47 antibodies and cytokines |
| KR20220028090A (ko) * | 2019-06-28 | 2022-03-08 | 카파 테라퓨틱스 리미티드 | 이식 반응에 저항하는 세포 및 방법 |
| JP2022548069A (ja) * | 2019-09-11 | 2022-11-16 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | キメラ直交受容体タンパク質および使用方法 |
| US20220401537A1 (en) * | 2019-09-16 | 2022-12-22 | Fred Hutchinson Cancer Research Center | Chimeric receptor proteins and uses thereof |
| GB201913697D0 (en) * | 2019-09-23 | 2019-11-06 | King S College London | DAP10/DAP12 fusion polypeptides |
| AU2020362554A1 (en) * | 2019-10-08 | 2022-05-12 | Provincial Health Services Authority | Chimeric cytokine receptors |
| US20230030680A1 (en) * | 2020-01-07 | 2023-02-02 | St. Jude Children's Research Hospital, Inc | Chimeric gmcsf-il18 receptor |
| CN113249330A (zh) * | 2021-05-20 | 2021-08-13 | 深圳市先康达生命科学有限公司 | 免疫细胞及其应用 |
| EP4426722A4 (en) * | 2021-11-02 | 2025-12-10 | Fred Hutchinson Cancer Center | CANCER TREATMENTS USING CELL-TARGETING THERAPIES AND ASSOCIATED RESEARCH PROTOCOLS |
| AU2024233625A1 (en) | 2023-03-03 | 2025-09-18 | Arsenal Biosciences, Inc. | Systems targeting psma and ca9 |
| WO2025039159A1 (en) * | 2023-08-21 | 2025-02-27 | Hangzhou Hervor Therapeutics Co., Ltd | Synthetic cytokine signaling system, preparation method, and uses thereof |
| WO2025081123A1 (en) | 2023-10-12 | 2025-04-17 | Fred Hutchinson Cancer Center | Methods and compositions for improving t cell immunotherapy |
| WO2025085536A1 (en) * | 2023-10-16 | 2025-04-24 | Lankenau Institute For Medical Research | Biologic conjugates that inhibit production of inflammatory cells and methods of use |
| CN117511885B (zh) * | 2024-01-08 | 2024-06-11 | 青岛华赛伯曼医学细胞生物有限公司 | 提高识别和杀伤肿瘤能力的工程化til细胞及其应用 |
| WO2025245169A1 (en) | 2024-05-21 | 2025-11-27 | Fred Hutchinson Cancer Center | Immunotherapy cells equipped with a collagen-targeting payload |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| AU695869B2 (en) * | 1993-04-06 | 1998-08-27 | Fred Hutchinson Cancer Research Center | Chimeric cytokine receptors in lymphocytes |
| EP2706116A1 (en) * | 2001-01-17 | 2014-03-12 | Emergent Product Development Seattle, LLC | Binding domain-immunoglobulin fusion proteins |
| WO2008042814A2 (en) | 2006-09-29 | 2008-04-10 | California Institute Of Technology | Mart-1 t cell receptors |
| WO2013063419A2 (en) * | 2011-10-28 | 2013-05-02 | The Trustees Of The University Of Pennsylvania | A fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting |
| US9447194B2 (en) | 2012-02-13 | 2016-09-20 | Seattle Children's Hospital | Bispecific chimeric antigen receptors and encoding polynucleotides thereof |
| CN105452287A (zh) * | 2013-04-17 | 2016-03-30 | 贝勒医学院 | 免疫抑制性TGF-β信号转换器 |
-
2017
- 2017-04-20 CN CN201780037786.6A patent/CN109312304A/zh active Pending
- 2017-04-20 US US16/094,420 patent/US20190127435A1/en not_active Abandoned
- 2017-04-20 CA CA3021455A patent/CA3021455A1/en active Pending
- 2017-04-20 JP JP2018554677A patent/JP7198670B2/ja active Active
- 2017-04-20 ES ES17724147T patent/ES2981274T3/es active Active
- 2017-04-20 WO PCT/US2017/028693 patent/WO2017184901A1/en not_active Ceased
- 2017-04-20 EP EP17724147.8A patent/EP3445847B1/en active Active
-
2022
- 2022-09-01 JP JP2022139098A patent/JP2022164858A/ja not_active Ceased
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