JP2019513436A - 上気道に粒子を投与する装置及び方法 - Google Patents

上気道に粒子を投与する装置及び方法 Download PDF

Info

Publication number
JP2019513436A
JP2019513436A JP2018549233A JP2018549233A JP2019513436A JP 2019513436 A JP2019513436 A JP 2019513436A JP 2018549233 A JP2018549233 A JP 2018549233A JP 2018549233 A JP2018549233 A JP 2018549233A JP 2019513436 A JP2019513436 A JP 2019513436A
Authority
JP
Japan
Prior art keywords
substance
chamber
cavity
inhalation
mouthpiece
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018549233A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019513436A5 (enExample
Inventor
ジドゥルカ、アーノルド
Original Assignee
セルヴィス メディコー アーノルド エ ジョアン ジドゥルカ インコーポレーテッド
セルヴィス メディコー アーノルド エ ジョアン ジドゥルカ インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セルヴィス メディコー アーノルド エ ジョアン ジドゥルカ インコーポレーテッド, セルヴィス メディコー アーノルド エ ジョアン ジドゥルカ インコーポレーテッド filed Critical セルヴィス メディコー アーノルド エ ジョアン ジドゥルカ インコーポレーテッド
Publication of JP2019513436A publication Critical patent/JP2019513436A/ja
Publication of JP2019513436A5 publication Critical patent/JP2019513436A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L63/00Network architectures or network communication protocols for network security
    • H04L63/14Network architectures or network communication protocols for network security for detecting or protecting against malicious traffic
    • H04L63/1408Network architectures or network communication protocols for network security for detecting or protecting against malicious traffic by monitoring network traffic
    • H04L63/1416Event detection, e.g. attack signature detection
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L63/00Network architectures or network communication protocols for network security
    • H04L63/14Network architectures or network communication protocols for network security for detecting or protecting against malicious traffic
    • H04L63/1408Network architectures or network communication protocols for network security for detecting or protecting against malicious traffic by monitoring network traffic
    • H04L63/1425Traffic logging, e.g. anomaly detection
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L63/00Network architectures or network communication protocols for network security
    • H04L63/14Network architectures or network communication protocols for network security for detecting or protecting against malicious traffic
    • H04L63/1433Vulnerability analysis
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L67/00Network arrangements or protocols for supporting network services or applications
    • H04L67/01Protocols
    • H04L67/02Protocols based on web technology, e.g. hypertext transfer protocol [HTTP]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/007Syringe-type or piston-type sprayers or atomisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A61M11/008Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised by squeezing, e.g. using a flexible bottle or a bulb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0618Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0625Mouth
    • A61M2210/065Throat; Pharynx
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1028Larynx
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/13ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Computer Security & Cryptography (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Signal Processing (AREA)
  • Computing Systems (AREA)
  • Computer Hardware Design (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Medical Informatics (AREA)
  • Primary Health Care (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Mechanical Engineering (AREA)
  • Steroid Compounds (AREA)
JP2018549233A 2016-03-24 2017-01-11 上気道に粒子を投与する装置及び方法 Pending JP2019513436A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662312878P 2016-03-24 2016-03-24
US62/312,878 2016-03-24
PCT/CA2017/050027 WO2017161442A1 (en) 2016-03-24 2017-01-11 Device and method of delivering particles in the upper respiratory tract

Publications (2)

Publication Number Publication Date
JP2019513436A true JP2019513436A (ja) 2019-05-30
JP2019513436A5 JP2019513436A5 (enExample) 2020-02-13

Family

ID=59897024

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018549233A Pending JP2019513436A (ja) 2016-03-24 2017-01-11 上気道に粒子を投与する装置及び方法

Country Status (5)

Country Link
US (2) US11278684B2 (enExample)
EP (1) EP3432954B1 (enExample)
JP (1) JP2019513436A (enExample)
CN (1) CN109219463B (enExample)
WO (1) WO2017161442A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019125304A1 (en) * 2017-12-18 2019-06-27 National University Of Singapore Spacer device for an inhaler and method of manufacture thereof
US20210008305A1 (en) * 2018-03-09 2021-01-14 Health Research, Inc. Induction spacer for inhaler
CN111973848B (zh) * 2020-07-13 2022-09-02 四川省人民医院 一种吸入剂装置
US11172707B1 (en) * 2020-07-23 2021-11-16 Claude Harper Smoking assemblies and methods of smoking
US20240196972A1 (en) * 2022-12-14 2024-06-20 R.J. Reynolds Tobacco Company Aerosol delivery device with deflectable or collapsible housing
CN119405953B (zh) * 2024-12-10 2025-09-30 中国人民解放军陆军军医大学第一附属医院 吸入型药物的给药装置

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4796614A (en) * 1987-02-26 1989-01-10 Trutek Research, Inc. Collapsible inhalation valve
US5320094A (en) * 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
US20030159693A1 (en) * 2002-02-27 2003-08-28 Richard Melker Breath-activated, microprocessor controlled system for pulmonary drug delivery
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US6718969B1 (en) * 2002-05-28 2004-04-13 Darren Rubin Medication dosage inhaler system
WO2012026963A2 (en) * 2010-08-23 2012-03-01 Darren Rubin Systems and methods of aerosol delivery with airflow regulation
JP2013515581A (ja) * 2009-12-28 2013-05-09 ラ・ディフージョン・テクニーク・フランセーズ 鼻咽腔、鼻腔、または副鼻腔に対してエアゾールを経口投与するためのデバイス
WO2015042352A1 (en) * 2013-09-20 2015-03-26 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
US20160045685A1 (en) * 2014-08-13 2016-02-18 Elwha Llc Methods, systems, and devices related to a supplemental inhaler

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1586716A (en) 1925-04-06 1926-06-01 Jr Samuel P Snow Surgical instrument
US2788784A (en) 1955-08-23 1957-04-16 Herbert M Birch Means for administering medication orally into the respiratory organs
US4534343A (en) 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
US4790305A (en) 1986-06-23 1988-12-13 The Johns Hopkins University Medication delivery system
US5042467A (en) 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
US5570683A (en) * 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
US5040527A (en) 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
US5431154A (en) 1991-11-29 1995-07-11 Seigel; David Incentive metered dose inhaler
DE4237568C1 (de) * 1992-11-06 1994-05-11 Dieter Dipl Ing Dr Med Koehler Verfahren und Vorrichtung zum Erzeugen eines Aerosols
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US5522380A (en) 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
US5738087A (en) 1995-09-21 1998-04-14 King; Russell W. Aerosol medication delivery system
AT1175U1 (de) * 1995-10-02 1996-12-27 Wmc Mediation & Consulting Gmb Inhalationshilfsgerät
US5797392C1 (en) 1996-01-22 2001-01-09 Direct Haler As Inhaler
US5906202A (en) * 1996-11-21 1999-05-25 Aradigm Corporation Device and method for directing aerosolized mist to a specific area of the respiratory tract
US6039042A (en) 1998-02-23 2000-03-21 Thayer Medical Corporation Portable chamber for metered dose inhaler dispensers
US6026807A (en) * 1998-02-27 2000-02-22 Diemolding Corporation Metered dose inhaler cloud chamber
NZ521051A (en) * 2000-02-11 2003-07-25 Profile Respiratory Systems Lt Drug delivery apparatus
US8820316B2 (en) * 2000-02-11 2014-09-02 Respironics Respiratory Drug Delivery (Uk) Ltd Drug delivery apparatus
US7013896B2 (en) 2001-05-08 2006-03-21 Trudell Medical International Mask with inhalation valve
PL1670482T5 (pl) * 2003-09-16 2022-10-03 Covis Pharma Gmbh Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego
US7900625B2 (en) 2005-08-26 2011-03-08 North Carolina State University Inhaler system for targeted maximum drug-aerosol delivery
WO2008001132A1 (en) * 2006-06-27 2008-01-03 Brintech International Limited Inhaler
US20080066739A1 (en) * 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
GB2468794B (en) * 2006-11-28 2011-07-13 Optinose As Delivery devices
US8251876B2 (en) 2008-04-22 2012-08-28 Hill-Rom Services, Inc. Breathing exercise apparatus
WO2011162316A1 (ja) 2010-06-24 2011-12-29 公立大学法人名古屋市立大学 薬剤吸入器及び薬剤供給方法
US9757528B2 (en) * 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
US8770188B2 (en) 2011-03-31 2014-07-08 Carefusion 207, Inc. Metered dose inhaler spacer
WO2014046993A1 (en) * 2012-09-24 2014-03-27 Aerodesigns, Inc. Flow diverter for a mouthpiece of a particule delivery device
CN104436386B (zh) * 2014-11-14 2017-09-12 广州医科大学附属第一医院 辅助呼吸气雾气体的装置及调节呼吸气雾气体的方法
CN105396206A (zh) * 2015-11-27 2016-03-16 江苏鹿得医疗电子股份有限公司 带吸气感应间歇送风式医用超声波雾化器

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4796614A (en) * 1987-02-26 1989-01-10 Trutek Research, Inc. Collapsible inhalation valve
US5320094A (en) * 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
US20030159693A1 (en) * 2002-02-27 2003-08-28 Richard Melker Breath-activated, microprocessor controlled system for pulmonary drug delivery
US6718969B1 (en) * 2002-05-28 2004-04-13 Darren Rubin Medication dosage inhaler system
JP2013515581A (ja) * 2009-12-28 2013-05-09 ラ・ディフージョン・テクニーク・フランセーズ 鼻咽腔、鼻腔、または副鼻腔に対してエアゾールを経口投与するためのデバイス
WO2012026963A2 (en) * 2010-08-23 2012-03-01 Darren Rubin Systems and methods of aerosol delivery with airflow regulation
WO2015042352A1 (en) * 2013-09-20 2015-03-26 Virginia Commonwealth University Delivery of particles using hygroscopic excipients
US20160045685A1 (en) * 2014-08-13 2016-02-18 Elwha Llc Methods, systems, and devices related to a supplemental inhaler

Also Published As

Publication number Publication date
US20180050165A1 (en) 2018-02-22
CN109219463A (zh) 2019-01-15
CN109219463B (zh) 2021-05-11
EP3432954B1 (en) 2022-04-20
EP3432954A1 (en) 2019-01-30
US10391268B2 (en) 2019-08-27
US11278684B2 (en) 2022-03-22
WO2017161442A1 (en) 2017-09-28
US20180043112A1 (en) 2018-02-15
EP3432954A4 (en) 2020-03-04

Similar Documents

Publication Publication Date Title
US10391268B2 (en) Device and method of delivering particles in the upper respiratory tract
JP4350837B2 (ja) 肺への薬の吸入投与のための装置
US8397713B2 (en) Mouthpiece and flow rate controller for intrapulmonary delivery devices
EP1446172B1 (en) Inhalation device type DPI
EP1212111B1 (en) Inhalator with threshold-valve
JP5746213B2 (ja) 鼻咽腔、鼻腔、または副鼻腔に対してエアゾールを経口投与するためのデバイス
US11207476B2 (en) Flexible bag spacer device for an inhaler
CN110730674A (zh) 干粉吸入器和用于干粉吸入器的间隔装置
JP7182561B2 (ja) ネブライザ用スペーサ装置
EP3866894B1 (en) Pharmaceutical administration to neonates, infants and children
JP6941844B2 (ja) 患者の人工呼吸または呼吸補助の際の粉末エアロゾルの呼吸制御に適用するシステム、およびその作動方法
EP0050654A1 (en) SPIROMETRIC INHALATION DEVICE FOR ADMINISTERING MEDICAMENTS FOR LUNGS.
US20090064996A1 (en) Duo chamber
US20100000523A1 (en) Unichamber
CN104436386B (zh) 辅助呼吸气雾气体的装置及调节呼吸气雾气体的方法
US6701915B1 (en) Device for inhaling medicaments using supported pressure respiration
CN213884606U (zh) 用于吸入剂装置的可监控吸入量的吸入装置
CN213724177U (zh) 一种吸入力度可调式吸入剂装置
CN213789390U (zh) 一种设置有辅助推入结构的吸入剂装置
EP2666497A1 (en) An inhaler comprising a mouthpiece having an improved air channel
PL225116B1 (pl) Zestaw do podawania leku w postaci aerozolu dozowanego z pojemnika pod ciśnieniem

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20191225

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20191225

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20201225

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210216

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20210507

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20210716

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210816

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220118

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220415

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220617

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220719

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20221101

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20230530