JP2019511940A - 機械学習技法を用いたoctアンギオグラフィにおけるアーチファクトを減少させるための方法及び装置 - Google Patents
機械学習技法を用いたoctアンギオグラフィにおけるアーチファクトを減少させるための方法及び装置 Download PDFInfo
- Publication number
- JP2019511940A JP2019511940A JP2018543677A JP2018543677A JP2019511940A JP 2019511940 A JP2019511940 A JP 2019511940A JP 2018543677 A JP2018543677 A JP 2018543677A JP 2018543677 A JP2018543677 A JP 2018543677A JP 2019511940 A JP2019511940 A JP 2019511940A
- Authority
- JP
- Japan
- Prior art keywords
- octa
- data
- oct
- probability
- artifacts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 35
- 238000002583 angiography Methods 0.000 title description 11
- 238000010801 machine learning Methods 0.000 title description 2
- FCKYPQBAHLOOJQ-UHFFFAOYSA-N Cyclohexane-1,2-diaminetetraacetic acid Chemical compound OC(=O)CN(CC(O)=O)C1CCCCC1N(CC(O)=O)CC(O)=O FCKYPQBAHLOOJQ-UHFFFAOYSA-N 0.000 claims abstract 17
- 238000012549 training Methods 0.000 claims description 18
- 238000007781 pre-processing Methods 0.000 claims description 10
- 230000009466 transformation Effects 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 3
- 239000000284 extract Substances 0.000 claims description 2
- 239000011159 matrix material Substances 0.000 claims 1
- 230000009467 reduction Effects 0.000 abstract description 6
- 238000012014 optical coherence tomography Methods 0.000 description 48
- 230000002207 retinal effect Effects 0.000 description 14
- 238000003384 imaging method Methods 0.000 description 11
- 238000012545 processing Methods 0.000 description 11
- 210000004204 blood vessel Anatomy 0.000 description 10
- 238000000605 extraction Methods 0.000 description 9
- 210000001519 tissue Anatomy 0.000 description 9
- 208000005590 Choroidal Neovascularization Diseases 0.000 description 8
- 206010060823 Choroidal neovascularisation Diseases 0.000 description 8
- 230000017531 blood circulation Effects 0.000 description 7
- 238000012800 visualization Methods 0.000 description 7
- 238000005259 measurement Methods 0.000 description 6
- 210000001525 retina Anatomy 0.000 description 6
- 206010064930 age-related macular degeneration Diseases 0.000 description 5
- 208000002780 macular degeneration Diseases 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 230000002792 vascular Effects 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 210000003583 retinal pigment epithelium Anatomy 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 230000011218 segmentation Effects 0.000 description 3
- 210000005166 vasculature Anatomy 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 210000000981 epithelium Anatomy 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- MOFVSTNWEDAEEK-UHFFFAOYSA-M indocyanine green Chemical compound [Na+].[O-]S(=O)(=O)CCCCN1C2=CC=C3C=CC=CC3=C2C(C)(C)C1=CC=CC=CC=CC1=[N+](CCCCS([O-])(=O)=O)C2=CC=C(C=CC=C3)C3=C2C1(C)C MOFVSTNWEDAEEK-UHFFFAOYSA-M 0.000 description 2
- 229960004657 indocyanine green Drugs 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 238000012935 Averaging Methods 0.000 description 1
- 208000002177 Cataract Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 230000001594 aberrant effect Effects 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000004424 eye movement Effects 0.000 description 1
- 238000005206 flow analysis Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 238000007477 logistic regression Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 208000013441 ocular lesion Diseases 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 108091008695 photoreceptors Proteins 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000007637 random forest analysis Methods 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000004232 retinal microvasculature Effects 0.000 description 1
- 210000001210 retinal vessel Anatomy 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000012706 support-vector machine Methods 0.000 description 1
- 230000004218 vascular function Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
- G06V10/77—Processing image or video features in feature spaces; using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]; Blind source separation
- G06V10/774—Generating sets of training patterns; Bootstrap methods, e.g. bagging or boosting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0016—Operational features thereof
- A61B3/0025—Operational features thereof characterised by electronic signal processing, e.g. eye models
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0016—Operational features thereof
- A61B3/0041—Operational features thereof characterised by display arrangements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
- A61B3/1225—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation
- A61B3/1233—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation for measuring blood flow, e.g. at the retina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
- A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7253—Details of waveform analysis characterised by using transforms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
- A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T5/00—Image enhancement or restoration
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/20—Image preprocessing
- G06V10/30—Noise filtering
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V10/00—Arrangements for image or video recognition or understanding
- G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
- G06V10/764—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
- G06F2218/02—Preprocessing
- G06F2218/04—Denoising
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10028—Range image; Depth image; 3D point clouds
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/10—Image acquisition modality
- G06T2207/10072—Tomographic images
- G06T2207/10101—Optical tomography; Optical coherence tomography [OCT]
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/20—Special algorithmic details
- G06T2207/20172—Image enhancement details
- G06T2207/20182—Noise reduction or smoothing in the temporal domain; Spatio-temporal filtering
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30041—Eye; Retina; Ophthalmic
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30101—Blood vessel; Artery; Vein; Vascular
- G06T2207/30104—Vascular flow; Blood flow; Perfusion
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V2201/00—Indexing scheme relating to image or video recognition or understanding
- G06V2201/03—Recognition of patterns in medical or anatomical images
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Signal Processing (AREA)
- Pathology (AREA)
- Theoretical Computer Science (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- General Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Evolutionary Computation (AREA)
- Multimedia (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Software Systems (AREA)
- Databases & Information Systems (AREA)
- Computing Systems (AREA)
- Fuzzy Systems (AREA)
- Mathematical Physics (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Quality & Reliability (AREA)
- Hematology (AREA)
- Eye Examination Apparatus (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Image Analysis (AREA)
Abstract
Description
図1及び図2A〜図2Dは、Bスキャン(図1)及び正面(en face)画像(図2A〜2D)によって示されるように、臨床評価に基づく網膜病変のない正常被検者におけるプロジェクション・アーチファクトを示す。図2A〜図2Dは、正常な被検者のOCTA撮像の例示的な画像を示しており、図2Aは、4つの網膜層の正面(en face)画像、表層毛細管叢を示し、図2Bは、深層毛細血管叢を示し、図2Cは、網膜外層を示し、図2Dは脈絡膜毛細血管を示す。図2A〜2Dは、プロジェクション・アーチファクトが減少する前において前処理されたOCTAボリュームから生成されたものである。
図7は、プロジェクション・アーチファクト低減のために使用される分類器を訓練するためのステップを示すブロック図を示す。ブロック305に示すプロジェクション・アーチファクト低減プロセスで使用される分類器は、十分に大量のデータで事前に訓練することができる。図7は、分類器を訓練するためのステップを示す例示的な流れ図である。まず、ブロック701において、様々な年齢、性別及び網膜病変を有する対象からの共取得OCT及びOCTAボリュームデータを有する訓練データセットが、OCT/OCTAイメージャによって収集される。
Claims (10)
- アーチファクトを低減する方法であって、
OCT/OCTAイメージャからOCT/OCTAデータを取得するステップと、
OCTA/OCTボリュームデータを前処理するステップと、
前処理された前記OCTA/OCTボリュームデータから特徴を抽出するステップと、
前記OCTA/OCTボリュームデータを分類して確率決定データを提供するステップと、
前記確率決定データから割合データを決定するステップと、
前記割合データに応答してアーチファクトを減少させるステップと
を含む方法。 - 前記OCTA/OCTボリュームデータを前処理するステップは、
バックグラウンドノイズを超えるOCTA/OCT信号を有する領域を検出し、
前記バックグラウンドノイズを超えないOCTA/OCT信号の領域を除外し、
各OCTA/OCT−Aラインに沿ったランドマークを検出し、
全てのAスキャンを、選択したランドマークに合わせるために平坦化することと
を含む、請求項1に記載の方法。 - 前記特徴を抽出するステップは、前記OCTA/OCTデータの各基本単位内の特徴を抽出するステップを含む、請求項1に記載の方法。
- 前記基本単位は、単一のボクセルであり得る、請求項3に記載の方法。
- 前記基本単位は、複数のボクセルである、請求項3に記載の方法。
- 前記OCTA/OCTデータを分類することは、
各基本単位において、前記基本単位が分類カテゴリの組の1つに属する確率を表す確率決定データを返信することを含む、請求項1に記載の方法。 - 前記分類カテゴリの組は、純粋に真のフロー信号、純粋なアーチファクト信号、又は真のフロー信号及びアーチファクト信号の両方の混合を含む、請求項6に記載の方法。
- 前記OCTA/OCTデータを分類するステップは、訓練された分類器を使用して前記確率決定データを決定するステップを含む、請求項6に記載の方法。
- 前記訓練された分類器を訓練するステップをさらに含み、前記訓練された分類器を訓練することは、
トレーニングデータセットを提供し、
前記トレーニングデータセットを前処理し、
前記トレーニングデータセット内の特徴を抽出し、
前記トレーニングデータセットを分類して確率決定データを取得し、
前記確率決定データを人間のラベル付けされた確率データと比較し、
前記確率決定データが人間のラベル付けされた確率データと一致するように、訓練された分類器を改良することと
を含む、請求項8に記載の方法。 - 前記確率決定データから割合データを決定することは、
各カテゴリに属する基本単位の確率を、前記基本単位内の単一の真のフロー信号の
割合値に変換する変換式又は行列を含む、請求項1に記載の方法。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662297649P | 2016-02-19 | 2016-02-19 | |
US62/297,649 | 2016-02-19 | ||
US15/436,704 | 2017-02-17 | ||
PCT/US2017/018521 WO2017143300A1 (en) | 2016-02-19 | 2017-02-17 | Methods and apparatus for reducing artifacts in oct angiography using machine learning techniques |
US15/436,704 US10194866B2 (en) | 2016-02-19 | 2017-02-17 | Methods and apparatus for reducing artifacts in OCT angiography using machine learning techniques |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2019511940A true JP2019511940A (ja) | 2019-05-09 |
JP2019511940A5 JP2019511940A5 (ja) | 2020-01-23 |
JP7193343B2 JP7193343B2 (ja) | 2022-12-20 |
Family
ID=59625416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018543677A Active JP7193343B2 (ja) | 2016-02-19 | 2017-02-17 | 機械学習技法を用いたoctアンギオグラフィにおけるアーチファクトを減少させるための方法及び装置 |
Country Status (4)
Country | Link |
---|---|
US (1) | US10194866B2 (ja) |
JP (1) | JP7193343B2 (ja) |
CA (1) | CA3014998C (ja) |
WO (1) | WO2017143300A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022196583A1 (ja) * | 2021-03-19 | 2022-09-22 | 株式会社トプコン | グレード評価装置、眼科撮影装置、プログラム、記録媒体、およびグレード評価方法 |
JP7401470B2 (ja) | 2018-08-01 | 2023-12-19 | コストルツィオーニ ストルメンチ オフタルミチ シー.エス.オー. エス.アール.エル. | デジタル画像処理を通して望ましくないアーチファクトを除去する「フーリエドメイン」型の光干渉断層システム |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102016205718A1 (de) * | 2016-04-06 | 2017-10-12 | Siemens Healthcare Gmbh | Verfahren zur Darstellung von medizinischen Bilddaten |
CN110383019B (zh) * | 2017-02-28 | 2022-07-05 | 飞通尼护理股份有限公司 | 基于图像的手持式成像仪系统及使用方法 |
US10878574B2 (en) * | 2018-02-21 | 2020-12-29 | Topcon Corporation | 3D quantitative analysis of retinal layers with deep learning |
JP7262929B2 (ja) * | 2018-04-19 | 2023-04-24 | キヤノン株式会社 | 画像処理装置、画像処理方法及びプログラム |
JP7374615B2 (ja) * | 2018-05-31 | 2023-11-07 | キヤノン株式会社 | 情報処理装置、情報処理方法及びプログラム |
WO2019230643A1 (ja) * | 2018-05-31 | 2019-12-05 | キヤノン株式会社 | 情報処理装置、情報処理方法及びプログラム |
JP7229715B2 (ja) * | 2018-10-10 | 2023-02-28 | キヤノン株式会社 | 医用画像処理装置、医用画像処理方法及びプログラム |
JP7305401B2 (ja) * | 2018-09-06 | 2023-07-10 | キヤノン株式会社 | 画像処理装置、画像処理装置の作動方法、及びプログラム |
WO2020049828A1 (ja) * | 2018-09-06 | 2020-03-12 | キヤノン株式会社 | 画像処理装置、画像処理方法、及びプログラム |
JP2020039430A (ja) * | 2018-09-06 | 2020-03-19 | キヤノン株式会社 | 画像処理装置、画像処理方法及びプログラム |
WO2020054524A1 (ja) * | 2018-09-13 | 2020-03-19 | キヤノン株式会社 | 画像処理装置、画像処理方法及びプログラム |
JP7446730B2 (ja) * | 2018-09-13 | 2024-03-11 | キヤノン株式会社 | 画像処理装置、画像処理方法及びプログラム |
CN112822973A (zh) * | 2018-10-10 | 2021-05-18 | 佳能株式会社 | 医学图像处理装置、医学图像处理方法和程序 |
US10832074B2 (en) | 2019-03-08 | 2020-11-10 | International Business Machines Corporation | Uncertainty region based image enhancement |
JP7327954B2 (ja) * | 2019-03-11 | 2023-08-16 | キヤノン株式会社 | 画像処理装置および画像処理方法 |
WO2020183791A1 (ja) | 2019-03-11 | 2020-09-17 | キヤノン株式会社 | 画像処理装置および画像処理方法 |
JP7362403B2 (ja) * | 2019-03-11 | 2023-10-17 | キヤノン株式会社 | 画像処理装置および画像処理方法 |
EP4143781A1 (en) * | 2020-04-29 | 2023-03-08 | Carl Zeiss Meditec, Inc. | Oct en face pathology segmentation using channel-coded slabs |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09305757A (ja) * | 1996-05-14 | 1997-11-28 | Dainippon Screen Mfg Co Ltd | 画像のノイズ量判別装置およびノイズ量判別方法 |
WO2015154200A1 (en) * | 2014-04-07 | 2015-10-15 | Mimo Ag | Method for the analysis of image data representing a three-dimensional volume of biological tissue |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5785042A (en) * | 1995-02-14 | 1998-07-28 | Duke University | Magnetic resonance imaging method providing for correction of striation artifacts |
WO2011059655A1 (en) * | 2009-10-29 | 2011-05-19 | Optovue, Inc. | Enhanced imaging for optical coherence tomography |
US9269144B2 (en) | 2010-04-29 | 2016-02-23 | Friedrich-Alexander-Universitaet Erlangen-Nuernberg | Method and apparatus for motion correction and image enhancement for optical coherence tomography |
US20140276025A1 (en) * | 2013-03-14 | 2014-09-18 | Carl Zeiss Meditec, Inc. | Multimodal integration of ocular data acquisition and analysis |
US8885901B1 (en) * | 2013-10-22 | 2014-11-11 | Eyenuk, Inc. | Systems and methods for automated enhancement of retinal images |
US9759544B2 (en) | 2014-08-08 | 2017-09-12 | Carl Zeiss Meditec, Inc. | Methods of reducing motion artifacts for optical coherence tomography angiography |
-
2017
- 2017-02-17 JP JP2018543677A patent/JP7193343B2/ja active Active
- 2017-02-17 US US15/436,704 patent/US10194866B2/en active Active
- 2017-02-17 CA CA3014998A patent/CA3014998C/en active Active
- 2017-02-17 WO PCT/US2017/018521 patent/WO2017143300A1/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09305757A (ja) * | 1996-05-14 | 1997-11-28 | Dainippon Screen Mfg Co Ltd | 画像のノイズ量判別装置およびノイズ量判別方法 |
WO2015154200A1 (en) * | 2014-04-07 | 2015-10-15 | Mimo Ag | Method for the analysis of image data representing a three-dimensional volume of biological tissue |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7401470B2 (ja) | 2018-08-01 | 2023-12-19 | コストルツィオーニ ストルメンチ オフタルミチ シー.エス.オー. エス.アール.エル. | デジタル画像処理を通して望ましくないアーチファクトを除去する「フーリエドメイン」型の光干渉断層システム |
WO2022196583A1 (ja) * | 2021-03-19 | 2022-09-22 | 株式会社トプコン | グレード評価装置、眼科撮影装置、プログラム、記録媒体、およびグレード評価方法 |
Also Published As
Publication number | Publication date |
---|---|
CA3014998A1 (en) | 2017-08-24 |
US20170238877A1 (en) | 2017-08-24 |
WO2017143300A1 (en) | 2017-08-24 |
US10194866B2 (en) | 2019-02-05 |
JP7193343B2 (ja) | 2022-12-20 |
CA3014998C (en) | 2024-02-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7193343B2 (ja) | 機械学習技法を用いたoctアンギオグラフィにおけるアーチファクトを減少させるための方法及び装置 | |
US11935241B2 (en) | Image processing apparatus, image processing method and computer-readable medium for improving image quality | |
US10299677B2 (en) | Volume analysis and display of information in optical coherence tomography angiography | |
US9418423B2 (en) | Motion correction and normalization of features in optical coherence tomography | |
US8079711B2 (en) | Method for finding the lateral position of the fovea in an SDOCT image volume | |
JP4909377B2 (ja) | 画像処理装置及びその制御方法、コンピュータプログラム | |
EP2462863B1 (en) | Image processing apparatus for processing tomographic image of subject's eye, imaging system, method for processing image, and program | |
US10149610B2 (en) | Methods and systems for automatic detection and classification of ocular inflammation | |
JP6702764B2 (ja) | 光干渉断層データの処理方法、該方法を実行するためのプログラム、及び処理装置 | |
Yousefi et al. | Segmentation and quantification of blood vessels for OCT-based micro-angiograms using hybrid shape/intensity compounding | |
JP2015515894A (ja) | Oct血管造影データの解析および可視化 | |
JP2014516646A (ja) | 散乱媒質の深さ分解した物理的及び/又は光学的特性を決定する方法 | |
JP5631339B2 (ja) | 画像処理装置、画像処理方法、眼科装置、眼科システム及びコンピュータプログラム | |
Belghith et al. | A hierarchical framework for estimating neuroretinal rim area using 3D spectral domain optical coherence tomography (SD-OCT) optic nerve head (ONH) images of healthy and glaucoma eyes | |
WO2020137678A1 (ja) | 画像処理装置、画像処理方法及びプログラム | |
JP6748434B2 (ja) | 画像処理装置、推定方法、システム及びプログラム | |
EP3417401B1 (en) | Method for reducing artifacts in oct using machine learning techniques | |
Hassan et al. | Automated foveal detection in OCT scans | |
JP2020039430A (ja) | 画像処理装置、画像処理方法及びプログラム | |
Khalid et al. | Automated detection of drusens to diagnose age related macular degeneration using OCT images | |
JP2020058615A (ja) | 画像処理装置、学習済モデル、画像処理方法およびプログラム | |
Stankiewicz et al. | Volumetric segmentation of human eye blood vessels based on OCT images | |
JP2015144963A (ja) | 画像処理装置、画像処理方法及びプログラム | |
WO2022232555A1 (en) | Techniques for automatically segmenting ocular imagery and predicting progression of age-related macular degeneration | |
Mantri et al. | The effect of blood vessels on the computation of the scanning laser ophthalmoscope retinal thickness map |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RD01 | Notification of change of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7426 Effective date: 20190913 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20190913 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20191203 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20191203 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20201029 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20201117 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20210212 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20210401 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20210907 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20211201 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220128 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220614 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220914 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20221129 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20221208 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7193343 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |