JP2019505172A5 - - Google Patents

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JP2019505172A5
JP2019505172A5 JP2018527874A JP2018527874A JP2019505172A5 JP 2019505172 A5 JP2019505172 A5 JP 2019505172A5 JP 2018527874 A JP2018527874 A JP 2018527874A JP 2018527874 A JP2018527874 A JP 2018527874A JP 2019505172 A5 JP2019505172 A5 JP 2019505172A5
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antibody
variable region
chain variable
heavy chain
light chain
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JP2018527874A
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JP2019505172A (ja
JP6983779B2 (ja
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Priority claimed from PCT/US2016/064033 external-priority patent/WO2017095823A1/en
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Priority to JP2021190161A priority Critical patent/JP7206360B2/ja
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JP2018527874A 2015-11-30 2016-11-29 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化 Active JP6983779B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021190161A JP7206360B2 (ja) 2015-11-30 2021-11-24 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562261112P 2015-11-30 2015-11-30
US62/261,112 2015-11-30
PCT/US2016/064033 WO2017095823A1 (en) 2015-11-30 2016-11-29 Tumor-specific payload delivery and immune activation using a human antibody targeting a highly specific tumor cell surface antigen

Related Child Applications (1)

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JP2021190161A Division JP7206360B2 (ja) 2015-11-30 2021-11-24 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化

Publications (3)

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JP2019505172A JP2019505172A (ja) 2019-02-28
JP2019505172A5 true JP2019505172A5 (https=) 2020-01-16
JP6983779B2 JP6983779B2 (ja) 2021-12-17

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Application Number Title Priority Date Filing Date
JP2018527874A Active JP6983779B2 (ja) 2015-11-30 2016-11-29 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化
JP2021190161A Active JP7206360B2 (ja) 2015-11-30 2021-11-24 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化
JP2022212170A Ceased JP2023038231A (ja) 2015-11-30 2022-12-28 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化
JP2024090709A Pending JP2024110988A (ja) 2015-11-30 2024-06-04 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化

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Application Number Title Priority Date Filing Date
JP2021190161A Active JP7206360B2 (ja) 2015-11-30 2021-11-24 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化
JP2022212170A Ceased JP2023038231A (ja) 2015-11-30 2022-12-28 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化
JP2024090709A Pending JP2024110988A (ja) 2015-11-30 2024-06-04 非常に特異的な腫瘍細胞表面抗原を標的とするヒト抗体を用いた腫瘍特異的ペイロード送達及び免疫活性化

Country Status (10)

Country Link
US (3) US10946106B2 (https=)
EP (1) EP3383920B1 (https=)
JP (4) JP6983779B2 (https=)
CA (1) CA3006759A1 (https=)
DK (1) DK3383920T3 (https=)
ES (1) ES2975747T3 (https=)
FI (1) FI3383920T3 (https=)
PT (1) PT3383920T (https=)
SI (1) SI3383920T1 (https=)
WO (1) WO2017095823A1 (https=)

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JP7514186B2 (ja) * 2018-05-16 2024-07-10 ザ ジェネラル ホスピタル コーポレイション T細胞による認識を強化するよう抗原性を調節する方法
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US10925947B2 (en) * 2018-06-29 2021-02-23 Immatics Biotechnologies Gmbh A*03 restricted peptides for use in immunotherapy against cancers and related methods
WO2020263796A1 (en) * 2019-06-23 2020-12-30 Guangdong Tcrcure Biopharma Technology Co., Ltd. Anti-alpp car-t cell therapy
EP4034553A4 (en) * 2019-09-24 2023-10-11 Regents of the University of California NOVEL RECEPTORS FOR LIGAND-DEPENDENT TRANSCRIPTIONAL REGULATION
CN110974957B (zh) * 2019-12-06 2020-12-29 北京大学 包载过氧化氢酶且连接pd-l1抗体的脂质体在制备肿瘤治疗药物的应用
US20230080224A1 (en) * 2020-02-07 2023-03-16 Agency For Science, Technology And Research Antigen-binding molecules against alppl2 and/or alpp and uses thereof
TW202300172A (zh) * 2021-03-18 2023-01-01 美商思進公司 抗alpp/alppl2抗體及抗體藥物結合物
US20250145733A1 (en) * 2021-09-22 2025-05-08 The Regents Of The University Of California Tumor-specific bispecific immune cell engager
JP2024537991A (ja) 2021-10-14 2024-10-18 アーセナル バイオサイエンシズ インコーポレイテッド 共発現されるshRNAと論理ゲートシステムとを有する免疫細胞
US20250195639A1 (en) * 2021-10-20 2025-06-19 The Regents Of The University Of California Multi-epitope mrna sars-cov-2 vaccine for boosting immunity through the activation of cd4 and cd8 t cells as well as b lymphocytes
WO2023215746A2 (en) * 2022-05-02 2023-11-09 Javelin Oncology, Inc. Anti-alppl2 antibodies and chimeric antigen receptors, and compositions and methods of use
CN120882866A (zh) * 2022-12-21 2025-10-31 阿尔麦克探索有限公司 Alpp特异性变体抗原结合分子
AU2024260837A1 (en) 2023-04-25 2025-10-16 Arsenal Biosciences, Inc. Novel receptors for transcription regulation
WO2025064427A1 (en) * 2023-09-18 2025-03-27 R.P. Scherer Technologies, Llc Dual-payload antibody-drug conjugates and uses thereof

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