JP2019504101A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019504101A5 JP2019504101A5 JP2018540793A JP2018540793A JP2019504101A5 JP 2019504101 A5 JP2019504101 A5 JP 2019504101A5 JP 2018540793 A JP2018540793 A JP 2018540793A JP 2018540793 A JP2018540793 A JP 2018540793A JP 2019504101 A5 JP2019504101 A5 JP 2019504101A5
- Authority
- JP
- Japan
- Prior art keywords
- acamprosate
- piperazin
- phenylsulfonyl
- quinoline
- baclofen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16305128 | 2016-02-05 | ||
| EP16305128.7 | 2016-02-05 | ||
| EP17152720 | 2017-01-23 | ||
| EP17152720.3 | 2017-01-23 | ||
| PCT/EP2017/052470 WO2017134280A1 (en) | 2016-02-05 | 2017-02-03 | Novel combinatorial therapies of neurological disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019504101A JP2019504101A (ja) | 2019-02-14 |
| JP2019504101A5 true JP2019504101A5 (enExample) | 2020-03-12 |
| JP7027318B2 JP7027318B2 (ja) | 2022-03-01 |
Family
ID=58044028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018540793A Expired - Fee Related JP7027318B2 (ja) | 2016-02-05 | 2017-02-03 | 神経障害の新規の併用療法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10799499B2 (enExample) |
| JP (1) | JP7027318B2 (enExample) |
| CN (1) | CN109069450A (enExample) |
| AU (1) | AU2017216288B2 (enExample) |
| CA (1) | CA3012900A1 (enExample) |
| WO (1) | WO2017134280A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3088715A1 (en) * | 2018-01-29 | 2019-08-01 | Pharnext | Baclofen and acamprosate based therapy of alzheimer's disease in patients having lost responsiveness to acetylcholinesterase inhibitor therapy |
| AU2020219140A1 (en) * | 2019-02-05 | 2022-03-24 | Georgetown University | Materials and methods for treating a neurodegenerative disease |
| CN114181201B (zh) * | 2020-09-15 | 2023-12-01 | 香港科技大学 | 作为针对各种神经退行性疾病的潜在治疗剂的新化合物 |
| WO2025151884A1 (en) * | 2024-01-12 | 2025-07-17 | Parsons C Lowell | Use of glycosaminoglycan sulfated polysaccharides such as sodium pentosan polysulfate in combination with permeation agents to treat alzheimer's disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1497266E (pt) | 2002-03-27 | 2008-09-10 | Glaxo Group Ltd | Derivados de quinolina e sua utilização como ligandos 5-ht6 |
| AU2006308889A1 (en) * | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| WO2008086492A1 (en) * | 2007-01-11 | 2008-07-17 | Xenoport, Inc. | Sustained release oral dosage forms of a prodrug of r-baclofen and methods of treatment |
| WO2008087123A2 (en) * | 2007-01-16 | 2008-07-24 | Solvay Pharmaceuticals B.V. | Use of 5-ht6 antagonists to prevent relapse into addiction |
| EP2120950B1 (en) * | 2007-03-21 | 2012-07-04 | Glaxo Group Limited | Use of quinoline derivatives in the treatment of pain |
| EP2254564A1 (en) | 2007-12-12 | 2010-12-01 | Glaxo Group Limited | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline |
| SI2282778T1 (sl) * | 2008-04-29 | 2017-07-31 | Pharnext | Novi terapevtski pristopi za zdravljenje Alzheimerjeve bolezni in sorodnih motenj z modulacijo angiogenezo |
| US9820978B2 (en) * | 2011-03-01 | 2017-11-21 | Pharnext | Treatment of cerebral ischemia |
| US9248111B2 (en) | 2011-03-01 | 2016-02-02 | Pharnext | Therapeutic approaches for treating parkinson's disease |
| UA113165C2 (xx) | 2011-03-01 | 2016-12-26 | Застосування комбінації баклофену і акампросату для лікування неврологічних захворювань та композиція, яка містить баклофен і акампросат | |
| EP2705843A1 (en) * | 2012-09-05 | 2014-03-12 | Pharnext | Therapeutic approaches for treating epilepsy and related disorders through reduction of epileptogenesis |
-
2017
- 2017-02-03 AU AU2017216288A patent/AU2017216288B2/en not_active Ceased
- 2017-02-03 WO PCT/EP2017/052470 patent/WO2017134280A1/en not_active Ceased
- 2017-02-03 JP JP2018540793A patent/JP7027318B2/ja not_active Expired - Fee Related
- 2017-02-03 US US16/074,783 patent/US10799499B2/en not_active Expired - Fee Related
- 2017-02-03 CN CN201780010107.6A patent/CN109069450A/zh active Pending
- 2017-02-03 CA CA3012900A patent/CA3012900A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10434109B2 (en) | Compositions for treating neurological disorders | |
| JP5987008B2 (ja) | バクロフェンおよびアカンプロセートに基づく神経疾患の治療 | |
| JP6619744B2 (ja) | 神経障害の処置のためのバクロフェン、アカンプロセート、及び中鎖トリグリセライドの併用 | |
| EA032881B1 (ru) | Применение торасемида для лечения болезни альцгеймера или родственного болезни альцгеймера расстройства или травмы спинного мозга | |
| US9931326B2 (en) | Composition comprising torasemide and baclofen for treating neurological disorders | |
| JP7027318B2 (ja) | 神経障害の新規の併用療法 | |
| JP2019504101A5 (enExample) | ||
| JP7065880B2 (ja) | アルツハイマー病のイダロピルジン系組合せ療法 | |
| JP6430445B2 (ja) | バクロフェンおよびアカンプロセートに基づく神経疾患の治療 | |
| EP3411025A1 (en) | Novel combinatorial therapies of neurological disorders | |
| HK1233960A1 (en) | Combination of baclofen, acamprosate and medium chain triglycerides for the treatment of neurological disorders |