JP2019504101A5 - - Google Patents

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Publication number
JP2019504101A5
JP2019504101A5 JP2018540793A JP2018540793A JP2019504101A5 JP 2019504101 A5 JP2019504101 A5 JP 2019504101A5 JP 2018540793 A JP2018540793 A JP 2018540793A JP 2018540793 A JP2018540793 A JP 2018540793A JP 2019504101 A5 JP2019504101 A5 JP 2019504101A5
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JP
Japan
Prior art keywords
acamprosate
piperazin
phenylsulfonyl
quinoline
baclofen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2018540793A
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English (en)
Japanese (ja)
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JP7027318B2 (ja
JP2019504101A (ja
Filing date
Publication date
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Priority claimed from PCT/EP2017/052470 external-priority patent/WO2017134280A1/en
Publication of JP2019504101A publication Critical patent/JP2019504101A/ja
Publication of JP2019504101A5 publication Critical patent/JP2019504101A5/ja
Application granted granted Critical
Publication of JP7027318B2 publication Critical patent/JP7027318B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2018540793A 2016-02-05 2017-02-03 神経障害の新規の併用療法 Expired - Fee Related JP7027318B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16305128.7 2016-02-05
EP16305128 2016-02-05
EP17152720.3 2017-01-23
EP17152720 2017-01-23
PCT/EP2017/052470 WO2017134280A1 (en) 2016-02-05 2017-02-03 Novel combinatorial therapies of neurological disorders

Publications (3)

Publication Number Publication Date
JP2019504101A JP2019504101A (ja) 2019-02-14
JP2019504101A5 true JP2019504101A5 (enExample) 2020-03-12
JP7027318B2 JP7027318B2 (ja) 2022-03-01

Family

ID=58044028

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018540793A Expired - Fee Related JP7027318B2 (ja) 2016-02-05 2017-02-03 神経障害の新規の併用療法

Country Status (6)

Country Link
US (1) US10799499B2 (enExample)
JP (1) JP7027318B2 (enExample)
CN (1) CN109069450A (enExample)
AU (1) AU2017216288B2 (enExample)
CA (1) CA3012900A1 (enExample)
WO (1) WO2017134280A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021512174A (ja) * 2018-01-29 2021-05-13 ファーネクストPharnext アセチルコリンエステラーゼ阻害剤療法に対する反応性を失った患者におけるアルツハイマー病のバクロフェン及びアカンプロセートを用いた療法
AU2020219140A1 (en) * 2019-02-05 2022-03-24 Georgetown University Materials and methods for treating a neurodegenerative disease
CN114181201B (zh) * 2020-09-15 2023-12-01 香港科技大学 作为针对各种神经退行性疾病的潜在治疗剂的新化合物
WO2025151884A1 (en) * 2024-01-12 2025-07-17 Parsons C Lowell Use of glycosaminoglycan sulfated polysaccharides such as sodium pentosan polysulfate in combination with permeation agents to treat alzheimer's disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1497266T1 (sl) * 2002-03-27 2008-10-31 Glaxo Group Ltd Derivati kinolina in njihova uporaba kot ligandi 5-ht6
WO2007053596A1 (en) * 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
ATE511392T1 (de) * 2007-01-11 2011-06-15 Xenoport Inc Verzögert freigesetzte orale dosierungsformen eines prodrugs von r-baclofen und behandlungsverfahren damit
WO2008087123A2 (en) * 2007-01-16 2008-07-24 Solvay Pharmaceuticals B.V. Use of 5-ht6 antagonists to prevent relapse into addiction
WO2008113818A1 (en) * 2007-03-21 2008-09-25 Glaxo Group Limited Use of quinoline derivatives in the treatment of pain and irritable bowel syndrome
EP2254564A1 (en) * 2007-12-12 2010-12-01 Glaxo Group Limited Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline
DK2282778T3 (en) * 2008-04-29 2017-05-01 Pharnext NEW THERAPEUTIC APPROACHES TO TREAT ALZHEIMER'S DISEASE AND RELATED DISEASES THROUGH A MODULATION OF ANGIOGENIC
US9248111B2 (en) * 2011-03-01 2016-02-02 Pharnext Therapeutic approaches for treating parkinson's disease
UA115968C2 (uk) * 2011-03-01 2018-01-25 Фарнекст Нові композиції для лікування неврологічних захворювань
SI2560631T1 (sl) * 2011-03-01 2014-06-30 Pharnext Na baklofenu in akamprosatu temeljeäśa terapija nevroloĺ kih nepravilnosti
EP2705843A1 (en) * 2012-09-05 2014-03-12 Pharnext Therapeutic approaches for treating epilepsy and related disorders through reduction of epileptogenesis

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