JP2019090111A5 - - Google Patents
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- Publication number
- JP2019090111A5 JP2019090111A5 JP2018213201A JP2018213201A JP2019090111A5 JP 2019090111 A5 JP2019090111 A5 JP 2019090111A5 JP 2018213201 A JP2018213201 A JP 2018213201A JP 2018213201 A JP2018213201 A JP 2018213201A JP 2019090111 A5 JP2019090111 A5 JP 2019090111A5
- Authority
- JP
- Japan
- Prior art keywords
- metal nanoparticles
- nanoparticles
- modified metal
- modified
- silver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000002082 metal nanoparticle Substances 0.000 claims 16
- 125000004122 cyclic group Chemical group 0.000 claims 6
- 239000004721 Polyphenylene oxide Substances 0.000 claims 5
- 229920000570 polyether Polymers 0.000 claims 5
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 4
- 229910052737 gold Inorganic materials 0.000 claims 4
- 239000010931 gold Substances 0.000 claims 4
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims 3
- 239000002105 nanoparticle Substances 0.000 claims 3
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000002616 MRI contrast agent Substances 0.000 claims 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000002534 radiation-sensitizing agent Substances 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000004332 silver Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims 1
Claims (10)
- 金属ナノ粒子と、前記金属ナノ粒子を修飾する環状ポリエーテルと、を含む、修飾金属ナノ粒子。
- 前記金属ナノ粒子が、金、銀、酸化鉄、酸化チタン又はこれらの複合体から構成されている、請求項１に記載の修飾金属ナノ粒子。
- 前記金属ナノ粒子が金ナノ粒子又は銀ナノ粒子である、請求項１又は２に記載の修飾金属ナノ粒子。
- 前記金属ナノ粒子の平均粒径が１～１０００ｎｍである、請求項１～３のいずれか一項に記載の修飾金属ナノ粒子。
- 前記環状ポリエーテルが環状ポリエチレンオキシドである、請求項１～４のいずれか一項に記載の修飾金属ナノ粒子。
- 前記環状ポリエーテルの数平均分子量が５００～２００００である、請求項１～５のいずれか一項に記載の修飾金属ナノ粒子。
- 前記金属ナノ粒子が金ナノ粒子であり、
前記金ナノ粒子に対する前記環状ポリエーテルの質量比が、５０～１５００である、請求項１～６のいずれか一項に記載の修飾金属ナノ粒子。 - 前記金属ナノ粒子が銀ナノ粒子であり、
前記銀ナノ粒子に対する前記環状ポリエーテルの質量比が、０．１～５０である、請求項１～６のいずれか一項に記載の修飾金属ナノ粒子。 - 請求項１～８のいずれか一項に記載の修飾金属ナノ粒子を含む、医薬組成物。
- 放射線増感剤、フォトサーマル治療剤又はＭＲＩ造影剤である、請求項９に記載の医薬組成物。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023130727A JP2023159222A (ja) | 2017-11-13 | 2023-08-10 | 修飾金属ナノ粒子及び医薬組成物 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017218620 | 2017-11-13 | ||
| JP2017218620 | 2017-11-13 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023130727A Division JP2023159222A (ja) | 2017-11-13 | 2023-08-10 | 修飾金属ナノ粒子及び医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019090111A JP2019090111A (ja) | 2019-06-13 |
| JP2019090111A5 true JP2019090111A5 (ja) | 2022-04-01 |
| JP7376901B2 JP7376901B2 (ja) | 2023-11-09 |
Family
ID=66431157
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018213201A Active JP7376901B2 (ja) | 2017-11-13 | 2018-11-13 | 修飾金属ナノ粒子及び医薬組成物 |
| JP2023130727A Pending JP2023159222A (ja) | 2017-11-13 | 2023-08-10 | 修飾金属ナノ粒子及び医薬組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023130727A Pending JP2023159222A (ja) | 2017-11-13 | 2023-08-10 | 修飾金属ナノ粒子及び医薬組成物 |
Country Status (2)
| Country | Link |
|---|---|
| US (1) | US11116793B2 (ja) |
| JP (2) | JP7376901B2 (ja) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2005082561A1 (ja) | 2004-02-27 | 2007-10-25 | 有限会社サンサーラコーポレーション | コロイダル金属 |
| JP4476899B2 (ja) | 2005-08-17 | 2010-06-09 | 日本電信電話株式会社 | 金属ナノ微粒子複合体およびその製造方法、金属ナノ微粒子複合体凝集物およびその製造方法 |
| US9440849B2 (en) * | 2009-01-15 | 2016-09-13 | Cornell University | Nanoparticle organic hybrid materials (NOHMS) |
| EP2275137A1 (en) | 2009-07-10 | 2011-01-19 | Nanobiotix | Metallic nanoparticles, preparation and uses thereof |
| JP5641385B2 (ja) | 2009-07-27 | 2014-12-17 | 独立行政法人物質・材料研究機構 | 樹枝状部分を有する金属ナノ粒子及びその製法 |
| KR101651915B1 (ko) | 2009-09-14 | 2016-08-29 | 한화케미칼 주식회사 | 금속 나노입자 수계 분산액의 제조방법 |
| US9156088B2 (en) | 2009-12-11 | 2015-10-13 | Tokyo University Of Science Educational Foundation Administrative Organization | Au—Ag core-shell nanorod particles and method for producing same |
| US8226985B2 (en) * | 2010-01-28 | 2012-07-24 | International Business Machines Corporation | Surface modified nanoparticles, methods of their preparation, and uses thereof for gene and drug delivery |
| US8795924B2 (en) * | 2012-09-12 | 2014-08-05 | GM Global Technology Operations LLC | Crown ether containing PEM electrode |
| US9983327B2 (en) * | 2012-10-26 | 2018-05-29 | Board Of Regents, The University Of Texas System | Polymer coated nanoparticles |
| JP6216934B2 (ja) | 2013-03-26 | 2017-10-25 | 国立大学法人信州大学 | 金属ナノ粒子の形成方法 |
| MA38709A1 (fr) | 2013-06-20 | 2018-05-31 | Nanobiotix | Compositions et procédés pour une utilisation en diagnostic médical |
-
2018
- 2018-11-13 US US16/188,509 patent/US11116793B2/en active Active
- 2018-11-13 JP JP2018213201A patent/JP7376901B2/ja active Active
-
2023
- 2023-08-10 JP JP2023130727A patent/JP2023159222A/ja active Pending
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