JP2019068897A - Cap for anesthesia syringe body, injector and coating method of surface anesthetic medical agent - Google Patents

Abstract

To suppress damage of a patient's skin when a skin analyte is collected.SOLUTION: A cap for an anesthesia syringe of the present invention is the cap attached to the tip of an anesthesia syringe body for extruding an anesthesia medical agent by extruding a cartridge with the anesthesia medical agent filled therein using a syringe. The cap is characterized by having a fixing part fixed to the anesthesia syringe body, a hollow needle inserted in the cartridge, a spread space connected to the tip of the hollow needle and spreading the anesthesia medical agent, and multiple micro-needles formed of a through-hole for ejecting the anesthesia medical agent from the spread space.SELECTED DRAWING: Figure 4

Description

The present invention is suitable for use in, for example, a cap for an anesthetic syringe body used for dental anesthesia, an injector and a method of applying a surface anesthetic agent.

  In recent years, as anesthesia performed at the time of dental treatment, two types, surface anesthesia and local anesthesia (this anesthesia) are common (for example, refer to patent documents 1). First, an anesthetic agent is applied or sprayed onto the mucous membrane or skin by surface anesthesia to adhere / permeate, and then local anesthesia by injection is performed.

International Publication WO2011 / 1001676

  However, since injection for local anesthesia is accompanied by pain and visual fear, there is a problem that the patient is mentally burdened.

  The present invention has been made to solve such problems, and its object is to provide a cap for an anesthetic syringe body, an injector and a method of applying a surface anesthetic agent capable of alleviating the mental burden on a patient. It is a thing.

In order to solve such problems, the cap for the anesthetic syringe body of the present invention is
A cap attached to a tip of an anesthetic syringe main body for pushing out an anesthetic agent by pushing out a cartridge containing an anesthetic agent with a syringe;
A fixing portion fixed to the anesthetic syringe body;
A hollow needle inserted into the cartridge;
A diffusion space connected to the tip of the hollow needle for spreading the anesthetic agent,
And a plurality of microneedles formed with through holes for discharging the anesthetic agent from the diffusion space.

Further, the injector of the present invention is
A microneedle array having a plurality of microneedles in which through holes are formed;
A capsule containing an infusate disposed on the back of the microneedle array;
It is characterized by comprising a flexible sheet-like material, and a sealing part covering the capsule and sealing the back side of the microneedle array.

  In the method for applying a surface anesthetic agent of the present invention, the surface of the microneedle sheet on which a plurality of microneedles are formed is immersed in the surface anesthetic agent, and then the surface of the microneedle sheet is attached to the area to be anesthetized It is characterized by attaching.

  The present invention can realize a skin sample collecting method and a microneedle capable of suppressing damage to the skin of a patient.

It is the schematic which shows the structure of the microneedle patch in 1st Embodiment. It is the schematic which shows the structure (1) of the conventional syringe body for anesthesia. It is the schematic which shows the structure (2) of the conventional syringe body for anesthesia. FIG. 10 is a schematic view for explaining the use of the microneedle cap in the second embodiment. It is the schematic which shows the structure of the microneedle cap in 2nd Embodiment. It is a schematic diagram showing composition (1) of an applicator in a 2nd embodiment. It is the schematic which shows the structure (2) of the applicator in 2nd Embodiment. It is the schematic which shows the modification (1) of the microneedle cap in 2nd Embodiment. It is the schematic which shows the modification (2) of the microneedle cap in 2nd Embodiment. It is the schematic which shows the structure (1) of the injector in 3rd Embodiment. It is the schematic which shows the structure (2) of the injector in 3rd Embodiment. It is the schematic where it uses for description of use (1) of the injector in 3rd Embodiment. It is the schematic where it uses for description of use (2) of the injector in 3rd Embodiment. It is the schematic which shows the modification of the injector in 3rd Embodiment.

First Embodiment
Hereinafter, embodiments of the present invention will be described with reference to the drawings.

  In the present invention, use of a bioabsorbable polymer is assumed when injecting anesthesia using a microneedle. Many of the bioabsorbable polymers are characterized by their ability to dissolve and wet in water, making them difficult to contact with aqueous anesthetic agents over time. Therefore, in the present invention, an anesthetic agent is infused into an anesthetic target site immediately after contact with the anesthetic agent immediately before use.

  1 shown in FIG. 1 shows a microneedle sheet as a whole. It is assumed that the microneedle patch 1 adheres an anesthetic agent to the microneedle 3 and affixes it to an anesthesia target location to be anesthetized.

  The microneedle patch 1 is formed with a plurality of microneedles 3 projecting from a surface 2A which is the surface side of the microneedle array 2. The size of the microneedle patch 1 and the number of the microneedles 3 are not limited, and it is preferable that the microneedle patch 1 having a size according to the size of the affected area be appropriately selected and used.

  On the back side of the microneedle array 2, a peripheral sheet 5 larger than the base sheet is attached. The peripheral sheet 5 is not formed with microneedles, and is provided to increase the size of the entire microneedle patch 1 to facilitate handling and to secure a place for an anesthesia practitioner to grasp.

  As shown in FIGS. 1B and 1C, the shape and size of the microneedle patch 1 are not limited, and various shapes such as circular, semicircular, rectangular, square and the like are adopted. Further, the peripheral sheet 5 does not have to be provided on the entire periphery of the microneedle array 2 and is preferably provided on at least one side. Since there is a portion where the peripheral sheet 5 does not form the peripheral edge of the microneedle array 2, regardless of the size and shape of the peripheral sheet 5, it is easy to position the microneedle 3 at the location where the practitioner wants to anesthetize Become.

  The thickness of the microneedle array 2 is not particularly limited, but is preferably 10 μm or more and 300 μm or less. It is also possible to integrally form the peripheral sheet 5 as the peripheral part of the microneedle array 2.

  The microneedle 3 preferably has a needle peak height from the surface 2A to the apex of approximately 30 to 500 μm. If it is smaller than 30 μm, the top of the microneedle 3 can not reach the skin to a sufficient depth, and if it is 500 μm or more, it is difficult to obtain sufficient structural strength, which is not preferable.

  Although no holes or holes are formed in the microneedle 3 in FIG. 1, the surface area of the microneedle array may be increased by providing the holes or holes (not shown) in the microneedle 3. It is possible. The radius of the hole or the hole is not particularly limited, but is preferably 1 μm or more and 30 μm or less. If the radius is too small, the skin side can not be inserted into the hole, and if the radius is too large, the physical strength necessary for the microneedle 3 can not be maintained, which is not preferable.

  In addition, when forming a hole in the microneedle 3, the hole can be filled with an anesthetic drug by causing a capillary phenomenon in relation to the anesthetic drug, and more anesthetic drug is applied to an anesthesia target location It is possible to Further, in the case of using a gel-like anesthetic drug, it is possible to apply more anesthetic drug to an anesthesia target site by forming the hole and the hole part larger.

  As materials of the microneedle array 2 and the microneedles 3, it is preferable to use a bioabsorbable material which is harmless to the human body and is absorbed by adjustment.

  As a bioabsorbable material, only one type may be contained, or two or more types may be mixed. In addition, the ratio of this main component is the weight after the completion of the whole processing process of a to-be-processed object, and does not contain what is called a solvent component which evaporates intentionally at the drying process after formation of microprotrusion. That is, it is the ratio after the end of processing of the workpiece.

  Known compounds (synthetic polymers and natural polymers) can be used as bioabsorbable polymers. For example, ester compounds such as polylactic acid, polyglycolic acid, poly-ε caprolactone, poly-rho-dioxane, polymalic acid, acid anhydrides such as polyacid anhydride, ortho ester compounds such as polyorthoester, carbonates such as polycarbonate Compounds, phosphazene compounds such as polydiaminophosphazenes, peptide compounds such as synthetic polypeptides, phosphate ester compounds such as polyphosphoester urethanes, carbon-carbon compounds such as polycyanoacrylates, poly-β-hydroxybutyric acid, polymalic acid, etc. Ester compounds, polyamino acids, chitin, chitosan, hyaluronic acid, sodium hyaluronate, pectic acid, galactan, starch, dextran, dextrin, alginic acid, sodium alginate, cellulose compounds Cellulose, Carboxymethylcellulose, Hydroxyethylcellulose, Hydroxypropylcellulose, Hydroxypropylcellulose, Methylcellulose), Gelatin, Agar, Celtrol, Leozan, Glycanth, Pullulan, Glycoside Compounds such as Gum arabic (Polysaccharides), Collagen, Gelatin, Fibrin, Gluten And peptide compounds (peptides, proteins) such as serum albumin; phosphate ester compounds (nucleic acids) such as deoxyribonucleic acid and ribonucleic acid; and vinyl compounds such as polyvinyl alcohol.

  The same material may be used as the material of the microneedle array 2 and the microneedle 3, and different materials may be used. The same material is used to form the microneedles 3 by shaving the microneedle array 2 or the like, and another material is used to form the microneedles 3 on the microneedle array 2 by molding or the like. Or the same material is suitably selected.

  For the microneedle patch 1, for example, various methods such as irradiation of a circularly polarized light vortex laser beam to the microneedle array 2, molding, etching, ion milling and the like can be used. The microneedles 3 are formed. In the case of forming a hole or a hole, after the formation of the microneedle 3, the hole is formed by, for example, laser irradiation or microhole processing using a microdrill.

  Also, the microneedle 3 and the hole or hole can be formed simultaneously. For example, the microneedle array 2 can be manufactured by solidifying a liquid polymer compound using a mold having a transfer pattern of microneedles having holes.

  Further, the height of the microneedle 3 can be maintained by offsetting (displacement) the hole or the hole from the top of the microneedle 3 and the apex from the tip of the hole or the hole in the microneedle 3 The area up to may serve to protect the hole or the hole.

  Furthermore, although not shown, it may be offset from the top of the microneedle 3 and inclined in the direction opposite to the direction in which the hole or the hole is offset. As a result, the volume inside the hole or the hole can be increased by the amount of inclination, and the physical strength of the microneedle 3 is maintained by increasing the distance from the surface of the microneedle 3 to the hole or the hole as much as possible. be able to.

  The microneedle patch 1 formed in this manner is used by sticking the apex of the microneedle 3 to a point to be anesthetized while the anesthetic agent is attached.

  For example, in the case of a liquid anesthetic agent having a low viscosity, after immersing the surface (the side on which the microneedles 3 are formed) of the microneedle patch 1 in the anesthetic agent enclosed in a small container, the peripheral sheet 5 is gripped with a finger. The microneedle array 2 is brought into contact with the surface anesthesia target, and the entire microneedle array 2 is pressed with a finger.

  Moreover, if it is a gel-like anesthetic drug with high viscosity, after the anesthetic drug is placed thickly on the entire microneedle array 2 with a finger, similarly, the peripheral sheet 5 is grasped with a finger, and the microneedle array 2 is a surface anesthesia target area The entire microneedle array 2 is pressed with a finger.

  Since an anesthetic agent can be sent in the inside of a gum by this, while becoming able to express the effect of anesthesia rapidly, it becomes possible to raise an effect. For this reason, it is possible to effectively apply surface anesthesia to a patient who has no effect of surface anesthesia until now, or to perform treatment that had to be followed by local anesthesia by only surface anesthesia. It becomes possible.

  Further, the microneedles 3 are hardly visible to the patient, and since the needles are thin, pain is hardly felt. Therefore, it is possible to significantly alleviate the mental and physical pain of the patient.

  In addition, in the above-mentioned embodiment, the case where microneedle patch 1 was used for dental anesthesia was described. The present invention is not limited to this, and may be used to relieve the pain of injection prior to, for example, ordinary intradermal injection or intramuscular injection. In this case, by applying an adhesive to the peripheral portion, it becomes possible to fix it to the anesthesia target part. Specifically, the entire surface of the peripheral sheet 5 can be used as a pressure-sensitive adhesive sheet, and the microneedle array 2 can be attached. In this case, the microneedle patch can be easily fixed by providing the peripheral portion around the periphery of the microneedle array.

  Moreover, in the above-mentioned embodiment, although the peripheral sheet 5 as a peripheral part was provided around the micro node array 2, the peripheral part is not necessarily essential. Also, the peripheral portion may be formed by not forming the microneedles on the peripheral edge of the microneedle array 2, that is, forming the microneedles only on the central portion.

Second Embodiment
Next, a second embodiment will be described with reference to FIGS. The second embodiment differs from the first embodiment in that the anesthetic agent is performed using an anesthetic syringe main body dedicated to local anesthesia. The code | symbol which added 100 to the location corresponding to 1st Embodiment is attached | subjected, and the description about the same location is abbreviate | omitted.

  FIGS. 2 and 3 illustrate a commonly used known anesthetic syringe body 1000. The anesthesia syringe main body 1000 has a structure for slidably housing a handle 1001 and a slide-type syringe 1002 connected to the handle inside the syringe case 1003.

  The syringe case 1003 is loaded with a disposable cartridge 1010 filled with an anesthetic agent. In addition, a locking portion 1004 is provided at the tip of the syringe case 1003, and a disposable cap 1020 is installed.

  In the cap 1020, the hollow needle 1022 is inserted into the cap body portion 1021. Of the hollow needles 1022, the back needle 1022 B that protrudes to the rear side of the cap main body 1021 is inserted into the inside of the syringe 1002 via the locking portion 1004. As a result, in the state where the cap 1020 is attached, the front needle 1022A protrudes from the cap main body portion 1021.

  When the practitioner pushes the handle 1001 in a state where the front needle 1022A is pierced into the anesthesia target location and moves the syringe 1002 to the distal end side, the anesthetic agent in the cartridge 1010 is pushed out, and from the tip of the hollow needle 1022 (front needle 1022A) An anesthetic agent is infused into the anesthesia target area.

  As shown in FIG. 4, the inventor of the present invention invented a microneedle cap 120 compatible with a conventional anesthesia syringe body by applying a microneedle to the cap.

  As shown in FIG. 4, the microneedle cap 120 of the present invention is held by the cap main body 121 through which the hollow needle 122 is inserted, the applicator holding portion 123 covering the front needle 122 A, and the tip of the applicator holding portion 123 And an applicator 130.

  The microneedle cap 120 is fixed to the anesthesia syringe main body 1000 by fixing the fixing portion 124 on the root side to the locking portion 1004 of the anesthesia syringe main body 1000 in a state where the rear needle 122B is inserted.

  The applicator 130 is installed at an angle of about 10 to 40 degrees with respect to the hollow needle 122 and the syringe 1002, and in a narrow mouth space, the applicator 130 can be easily brought into contact with an anesthesia target point which is a gum part. ing. In addition, the peripheral portion of the applicator main body 135 protrudes from the surface 102A of the microneedle array 102, so that it is possible to prevent the microneedle 103 from being pierced too deeply.

  As shown in FIG. 5, the applicator 130 secures the inner surface of the applicator body 135 and the back surface 132 B of the microneedle array 102 by the fixing portion (not shown) of the applicator body 135 firmly holding the microneedle array 102. And the diffusion space 136 is formed.

  The material of the microneedle array 102 is not particularly limited. For example, various inorganic materials such as metals such as aluminum and stainless alloys, silicon, carbon, ceramics, various mineral materials including calcium based minerals, and organic polymers Compounds and the like can be suitably used as the main component. As materials of the microneedle array 102 and the microneedles 103, it is particularly preferable to use a bioabsorbable material which is harmless to the human body and absorbed by a living body.

  As the bioabsorbable material, in addition to the bioabsorbable polymer material used in the first embodiment, metal materials and ceramic materials that use metals harmless to the organism such as calcium and potassium as raw materials are suitably used. Ru.

  In the present specification, the polymer compound means an organic compound having a weight average molecular weight Mw of 5000 or more. The main component means that the polymer compound is 50% by weight or more of the whole workpiece. As a high molecular compound, it is preferable that Tg (glass transition point) is 50 degreeC or more, More preferably, it is 70 degreeC or more. If the Tg is low, handling at normal temperature becomes difficult.

  As a high molecular compound, only 1 type may be contained and 2 or more types may be mixed. In addition, the ratio of this main component is the weight after the completion of the whole processing process of a to-be-processed object, and does not contain what is called a solvent component which evaporates intentionally at the drying process after formation of microprotrusion. That is, it is the ratio after the end of processing of the workpiece.

  As the polymer compound, known compounds (synthetic polymers and natural polymers) can be used. For example, in addition to various plastic materials such as PET (polyethylene terephthalate), polyethylene, polypropylene, acrylic resin, epoxy resin, polystyrene, etc., bioabsorbable polymers can be used.

  In the microneedle array 102, a plurality of microneedles 103 are formed on the surface 102A on the tip side. The microneedle 103 is formed with a through hole 104 penetrating to the back surface 102B.

  Further, the front needle 122A is inserted into the applicator body 135, and the hollow of the front needle 122A and the diffusion space 136 are connected. Therefore, the diffusion space 136 is a sealed space except being connected to the outside through the front needle 122A and the through hole 104.

  As shown in FIG. 7, when the practitioner pushes the handle 1001 with the microneedle 103 stuck in the anesthesia target part and moves the syringe 1002 to the tip side, the anesthetic agent in the cartridge 1010 is pushed out and the hollow needle 122 ( An anesthetic agent is injected from the tip of the front needle 122A) into the diffusion space 136 to the target area for anesthesia. Then, the anesthetic drug is discharged from the through hole 104 by the pressure at which the narcotic drug is injected from the hollow needle 122 into the diffusion space 136, and is injected into the anesthesia target location.

  Thus, since the microneedle cap 120 is fitted to the conventional anesthesia syringe main body, anesthesia can be performed without significantly changing the usability of the practitioner and causing almost no pain to the patient.

  As shown in FIGS. 8 and 9, the applicator 130 can be fixed to the cap body 150. In this case, the hollow needle 152 has its tip 152A bent inside the cap body 150 and is connected to the diffusion space 136 of the applicator 130.

  Although the microneedle cap is attached to the syringe for dental anesthesia in the above-mentioned embodiment, the present invention is not limited to this, and may be used for applications other than dental anesthesia. For example, a microneedle cap can be attached to a syringe for medical use. In addition, the microneedle cap or applicator can be fitted into a conventional syringe capable of replacing the hollow needle, so that the microneedle can be easily injected.

Third Embodiment
Next, a third embodiment will be described with reference to FIGS. The second embodiment differs from the second embodiment in that the diffusion space provided on the back side of the microneedle array is provided with an anesthesia capsule that contains an anesthetic agent. The code | symbol which added 100 to the location corresponding to 2nd Embodiment is attached | subjected, and the description about the same location is abbreviate | omitted.

  As shown in FIG. 10, in the injector 230, the microneedle array 202 is installed in a fixture 235, and a cover 242 covering an anesthesia capsule 241 containing an anesthetic agent is fixed to the back side of the fixture 235 . That is, the fixture 235 forms a diffusion space 236 by the back side of the microneedle array 202, that is, the back side surface 235A of the fixture 235 and the cover part 242.

  In the fixture 235, a through hole 237 connected to the through hole 204 of the microneedle array 202 is formed, and the diffusion space 236 and the through holes 237 and 204 are continuously connected. The cover portion 242 is formed of, for example, a flexible film-like material such as rubber. Although the thickness of the cover portion 242 is not limited, it is preferably about 20 to 2 mm in terms of strength and flexibility.

  The anesthetic capsule 241 is a thin membrane material and contains an anesthetic agent, and is formed to rupture with a relatively small impact. A protrusion 242A is formed inside the cover portion 242.

  As shown in FIG. 11 and FIG. 12, when the practitioner pushes the cover portion 242 with the microneedle 203 pierced into the anesthesia target part, the anesthetic capsule 241 is ruptured by the protrusion 242A, and the anesthetic agent is diffused into the diffusion space 236. To fill. Then, the anesthetic agent in the diffusion space 236 is discharged through the through holes 237 and 204 by the pressed pressure, and is injected into the anesthesia target part.

  As described above, in the injector 230, the anesthetic agent is encapsulated and ruptured immediately before the operation, whereby the anesthetic agent can be injected into the anesthesia target part in a simple operation and in a short time.

  In addition, as shown in FIG. 14, the fixing tool 235 is not essential, and it is also possible to directly fix the cover portion 242 to the microneedle array 202. Thereby, the configuration can be simplified.

  In the above-mentioned embodiment, although the case where an injector was used for dental anesthesia was described, the present invention is not limited to this. All medicines can be used as a substitute for the syringe for injection, and are preferably used, for example, for insulin and the like, especially for applications that do not come into the hands of a doctor and need to be injected by the patient himself.

<Operation and effect>
Hereinafter, the features of the invention group extracted from the above-described embodiment will be described by showing problems, effects, and the like as necessary. In the following, for ease of understanding, the corresponding configurations in the above-described embodiments are appropriately shown in parentheses, but the present invention is not limited to the specific configurations shown in parentheses. In addition, the meanings and examples of the terms described in the respective features may be applied as the meanings and examples of the terms described in the other features described in the same word.

The cap for the anesthetic syringe main body of the present invention is attached to the tip of the anesthetic syringe main body (the anesthetic syringe main body 1000) which pushes out the anesthetic drug by pushing out the cartridge (cartridge 1010) containing the anesthetic drug with the syringe (syringe 1002). Cap (micro needle cap 120),
A fixing unit (fixing unit 124) fixed to the anesthetic syringe body;
A hollow needle (hollow needle 122) inserted into the cartridge;
A diffusion space (a diffusion space 136) connected to the tip of the hollow needle for spreading the anesthetic agent;
And a plurality of microneedles (microneedles 103) in which through holes (through holes 104) for discharging the anesthetic agent from the diffusion space are formed.

  This makes it possible to perform an operation using the microneedle with little pain simply by using the cap on which the microneedle is installed for the already widely used anesthetic syringe body. Moreover, while being able to utilize the existing anesthesia syringe main body, a feeling of use of the practitioner can be brought close, and the practitioner can perform the treatment with the microneedle without discomfort.

Further, in the cap for an anesthesia syringe body, the diffusion space is
A microneedle sheet (microneedle array 102) having the microneedles;
It is characterized in that it is formed by an applicator (applicator 130) for holding the microneedle sheet and fixing the hollow needle.

  Thereby, the microneedle sheet which consists of a plane should just be set to an applicator, and an applicator can be easily produced.

In the cap for an anesthesia syringe body, the microneedle seat is
It is formed of a bioabsorbable material, and the sheet base and the microneedle are integrally formed.

  Thereby, the strength of the microneedle can be secured.

In the cap for an anesthetic syringe body the applicator comprises
It is characterized in that it is attached to the tip of a hollow needle that protrudes from the tip side of the cap.

  Since this hardly changes the usability as the syringe body for anesthesia, it is not necessary for the practitioner to feel the mental burden of changing to the microneedle.

Cap for an anesthetic syringe body The applicator is
It is characterized in that it is attached to the cap body.

By this,
The plurality of microneedles are
Installed at an angle to the hollow needle

The injector (injector 230) of the present invention comprises a microneedle array (microneedle array 202) having a plurality of microneedles (microneedles 203) in which through holes are formed.
A capsule (anesthetic capsule 241) disposed on the back of the microneedle array and containing an infusate;
It is characterized by comprising a flexible sheet-like material, and a sealing portion (cover portion 242) which covers the capsule and seals the back side of the microneedle array.

  As a result, since the capsule can be broken and the infusate can be diffused into the sealed portion when in use, the infusate can be easily injected into the living body by an operation of pushing the sealed portion.

Inside the seal in the injector:
A projection (projection 242A) for breaking the capsule is provided.

  This makes it easy to break the capsule.

  In the method for applying a surface anesthetic agent of the present invention, the surface of the microneedle sheet (microneedle array 2) on which a plurality of microneedles (microneedles 3) are formed is immersed in the surface anesthetic agent, and then the surface of the microneedle sheet It is characterized in that it is stuck on the anesthesia target part where you want to apply anesthesia.

  This makes it possible to perform an almost pain-free anesthesia treatment using the microneedle sheet of a simple configuration.

The microneedle seat is
It is characterized in that an unformed peripheral portion of the microneedle is formed.

  As a result, the practitioner can hold the peripheral portion, so that the microneedle does not stick to the fingers of the practitioner.

  In the method of applying a surface anesthetic agent, the microneedle is characterized by not having a through hole or a hole.

  Thereby, manufacture of a microneedle can be simplified.

In the method of applying a surface anesthetic drug, the microneedle is
It is characterized in that a through hole or a hole is formed.

  As a result, more surface anesthetic agents can be attached to the microneedles, and the effect of the surface anesthetic agents can be increased.

In the method of applying a surface anesthetic drug, the through hole is
It is characterized in that the surface anesthetic drug is sucked up by capillary action.

  As a result, more surface anesthetic agents can be held by the microneedles and injected into the living body, so that the effects of the surface anesthetic agents can be increased.

  The present invention can be applied to microneedles, for example in injection applications.

1: microneedle patch 2, 102, 202: microneedle array 3, 103, 203: microneedle 5: peripheral sheet 120: microneedle cap 121: cap main body 122: hollow needle 122A: front needle 122B: rear needle 123: Applicator holding portion 124: Fixing portion 130: Applicator 132B: Back surface 135: Applicator main body 136: Diffusion space 150: Cap main body portion 152: Hollow needle 204: Through hole 230: Injector 235: Fixing member 235A: Back side 236: Diffusion space 237: Through hole 241: Anesthetic capsule 242: Cover portion 242A: Projection 1000: Anesthesia syringe main body 1001: Handle 1002: Syringe 1003: Syringe case 1004: Locking portion 1010: Cartridge 1020: Cartridge Tip 1021: Cap body 1022: Hollow needle

Claims (13)

A cap attached to a tip of an anesthetic syringe main body for pushing out an anesthetic agent by pushing out a cartridge containing an anesthetic agent with a syringe;
A fixing portion fixed to the anesthetic syringe body;
A hollow needle inserted into the cartridge;
A diffusion space connected to the tip of the hollow needle for spreading the anesthetic agent,
A cap for an anesthesia syringe main body, comprising: a plurality of microneedles in which through holes for discharging the anesthetic agent from the diffusion space are formed. The diffusion space is
A microneedle sheet having the microneedles;
The cap for an anesthetic syringe body according to claim 1, characterized by an applicator that holds the microneedle sheet and fixes the hollow needle. The microneedle seat is
The cap for an anesthetic syringe body according to claim 1, wherein the cap is formed of a bioabsorbable material, and the sheet base and the microneedle are integrally formed. The applicator is
The cap for an anesthetic syringe body according to claim 1, wherein the cap is attached to the tip of a hollow needle projecting from the tip side of the cap. The applicator is
The cap for an anesthetic syringe body according to claim 1, which is attached to the cap body. The plurality of microneedles are
The cap for an anesthesia syringe body according to claim 1, wherein the cap is installed obliquely with respect to the hollow needle. A microneedle array having a plurality of microneedles in which through holes are formed;
A capsule containing an infusate disposed on the back of the microneedle array;
An injector comprising: a flexible sheet-like material; and a sealing portion covering the capsule and sealing the back side of the microneedle array. Inside the sealed part,
The injector according to claim 7, wherein a protrusion for breaking the capsule is provided. A surface of the microneedle sheet on which a plurality of microneedles are formed is immersed in a surface anesthetic agent, and then the surface of the microneedle sheet is attached to an anesthesia target location to be anesthetized. . The microneedle seat is
The method for applying a surface anesthetic agent according to claim 9, wherein the non-formed peripheral portion of the microneedle is formed. The microneedle is
The method for applying a surface anesthetic agent according to claim 9, which does not have a through hole. The microneedle is
The method for applying a surface anesthetic agent according to claim 9, wherein a through hole is formed. The through hole is
The method for applying a surface anesthetic agent according to claim 10, wherein the surface anesthetic agent is sucked up by capillary action.

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