JP2019052182A5 - - Google Patents
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- Publication number
- JP2019052182A5 JP2019052182A5 JP2018236137A JP2018236137A JP2019052182A5 JP 2019052182 A5 JP2019052182 A5 JP 2019052182A5 JP 2018236137 A JP2018236137 A JP 2018236137A JP 2018236137 A JP2018236137 A JP 2018236137A JP 2019052182 A5 JP2019052182 A5 JP 2019052182A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- cell sample
- pharmaceutical formulation
- composition
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 20
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 238000000034 method Methods 0.000 claims 12
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 210000001808 exosome Anatomy 0.000 claims 4
- 102000004127 Cytokines Human genes 0.000 claims 3
- 108090000695 Cytokines Proteins 0.000 claims 3
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 3
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 210000005259 peripheral blood Anatomy 0.000 claims 3
- 239000011886 peripheral blood Substances 0.000 claims 3
- 238000004153 renaturation Methods 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 2
- 230000032683 aging Effects 0.000 claims 2
- 229940035676 analgesics Drugs 0.000 claims 2
- 239000000730 antalgic agent Substances 0.000 claims 2
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 2
- 239000004599 antimicrobial Substances 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 150000003431 steroids Chemical class 0.000 claims 2
- 239000003981 vehicle Substances 0.000 claims 2
- 108700011259 MicroRNAs Proteins 0.000 claims 1
- 230000004635 cellular health Effects 0.000 claims 1
- 239000002679 microRNA Substances 0.000 claims 1
- 230000001483 mobilizing effect Effects 0.000 claims 1
- 108091027963 non-coding RNA Proteins 0.000 claims 1
- 102000042567 non-coding RNA Human genes 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461969694P | 2014-03-24 | 2014-03-24 | |
| US61/969,694 | 2014-03-24 | ||
| PCT/US2014/071667 WO2015095794A1 (en) | 2013-12-20 | 2014-12-19 | Compositions for cellular restoration and methods of making and using same |
| USPCT/US2014/071667 | 2014-12-19 | ||
| US14/577,978 US20150174166A1 (en) | 2013-12-20 | 2014-12-19 | Compositions for Cellular Restoration and Methods of Making and Using Same |
| US14/577,978 | 2014-12-19 | ||
| JP2016558732A JP6471302B2 (ja) | 2014-03-24 | 2015-03-24 | 細胞復元のための無細胞組成物及び同組成物の作成及び使用方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558732A Division JP6471302B2 (ja) | 2014-03-24 | 2015-03-24 | 細胞復元のための無細胞組成物及び同組成物の作成及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019052182A JP2019052182A (ja) | 2019-04-04 |
| JP2019052182A5 true JP2019052182A5 (https=) | 2019-05-16 |
| JP6900358B2 JP6900358B2 (ja) | 2021-07-07 |
Family
ID=54196315
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558732A Active JP6471302B2 (ja) | 2014-03-24 | 2015-03-24 | 細胞復元のための無細胞組成物及び同組成物の作成及び使用方法 |
| JP2018236137A Active JP6900358B2 (ja) | 2014-03-24 | 2018-12-18 | 細胞復元のための無細胞組成物及び同組成物の作成及び使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016558732A Active JP6471302B2 (ja) | 2014-03-24 | 2015-03-24 | 細胞復元のための無細胞組成物及び同組成物の作成及び使用方法 |
Country Status (4)
| Country | Link |
|---|---|
| EP (2) | EP4445915A3 (https=) |
| JP (2) | JP6471302B2 (https=) |
| CR (1) | CR20160495A (https=) |
| WO (1) | WO2015148534A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| US20150174166A1 (en) | 2013-12-20 | 2015-06-25 | Advanced ReGen Medical Technologies, LLC | Compositions for Cellular Restoration and Methods of Making and Using Same |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| US11203754B2 (en) | 2016-04-29 | 2021-12-21 | Advanced ReGen Medical Technologies, LLC | Microrna compositions and methods of making and using same |
| EP3740576A4 (en) | 2018-01-18 | 2021-10-20 | Advanced Regen Medical Technologies, LLC | THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008501336A (ja) * | 2004-06-02 | 2008-01-24 | ソースフアーム・インコーポレイテツド | Ｒｎａを含有する微小胞およびそのための方法 |
| US8693760B2 (en) * | 2009-06-25 | 2014-04-08 | Hitachi Medical Corporation | Medical imaging apparatus |
| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| US20120093885A1 (en) * | 2010-10-18 | 2012-04-19 | Northwestern University | Therapeutic vesicles |
| US8747915B1 (en) | 2011-09-14 | 2014-06-10 | Vincent C. Giampapa | Dietary supplement system for multifunctional anti-aging management and method of use |
| WO2013066368A1 (en) * | 2011-10-03 | 2013-05-10 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Use of mirna 126 to produce hematopoietic stem cells |
| US9427450B2 (en) * | 2012-01-31 | 2016-08-30 | Xon Cells, Inc. | Therapeutic immune modulation by stem cell secreted exosomes |
| US9295696B2 (en) * | 2012-06-08 | 2016-03-29 | University of Pittsburgh—of the Commonwealth System of Higher Education | Compositions and methods for restoring or rejuvenating stem/progenitor cell function |
| EP3563859B1 (en) * | 2012-08-13 | 2021-10-13 | Cedars-Sinai Medical Center | Cardiosphere-derived exosomes for tissue regeneration |
-
2015
- 2015-03-24 EP EP24177086.6A patent/EP4445915A3/en active Pending
- 2015-03-24 EP EP15768892.0A patent/EP3122333A4/en not_active Ceased
- 2015-03-24 CR CR20160495A patent/CR20160495A/es unknown
- 2015-03-24 JP JP2016558732A patent/JP6471302B2/ja active Active
- 2015-03-24 WO PCT/US2015/022285 patent/WO2015148534A1/en not_active Ceased
-
2018
- 2018-12-18 JP JP2018236137A patent/JP6900358B2/ja active Active
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