JP2018538118A5 - - Google Patents
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- Publication number
- JP2018538118A5 JP2018538118A5 JP2018545683A JP2018545683A JP2018538118A5 JP 2018538118 A5 JP2018538118 A5 JP 2018538118A5 JP 2018545683 A JP2018545683 A JP 2018545683A JP 2018545683 A JP2018545683 A JP 2018545683A JP 2018538118 A5 JP2018538118 A5 JP 2018538118A5
- Authority
- JP
- Japan
- Prior art keywords
- dialysate
- oxygen
- blood
- albumin
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 23
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 20
- 229910052760 oxygen Inorganic materials 0.000 claims 20
- 239000001301 oxygen Substances 0.000 claims 20
- 210000004369 blood Anatomy 0.000 claims 16
- 239000008280 blood Substances 0.000 claims 16
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 10
- 108010088751 Albumins Proteins 0.000 claims 9
- 102000009027 Albumins Human genes 0.000 claims 9
- 239000012528 membrane Substances 0.000 claims 6
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims 5
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 5
- 239000001569 carbon dioxide Substances 0.000 claims 5
- 239000007788 liquid Substances 0.000 claims 5
- 239000011575 calcium Substances 0.000 claims 4
- 150000002500 ions Chemical class 0.000 claims 4
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 4
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 208000010444 Acidosis Diseases 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 206010027417 Metabolic acidosis Diseases 0.000 claims 2
- 208000001647 Renal Insufficiency Diseases 0.000 claims 2
- 208000003826 Respiratory Acidosis Diseases 0.000 claims 2
- 239000007983 Tris buffer Substances 0.000 claims 2
- 230000002378 acidificating effect Effects 0.000 claims 2
- 210000001367 artery Anatomy 0.000 claims 2
- 239000000872 buffer Substances 0.000 claims 2
- 230000003139 buffering effect Effects 0.000 claims 2
- 229910052791 calcium Inorganic materials 0.000 claims 2
- 238000000502 dialysis Methods 0.000 claims 2
- -1 hydrogen cations Chemical class 0.000 claims 2
- 201000006370 kidney failure Diseases 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 230000001706 oxygenating effect Effects 0.000 claims 2
- 229920006395 saturated elastomer Polymers 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 210000003462 vein Anatomy 0.000 claims 2
- XOHUEYCVLUUEJJ-UHFFFAOYSA-N 2,3-Bisphosphoglyceric acid Chemical compound OP(=O)(O)OC(C(=O)O)COP(O)(O)=O XOHUEYCVLUUEJJ-UHFFFAOYSA-N 0.000 claims 1
- XOHUEYCVLUUEJJ-UHFFFAOYSA-I 2,3-Diphosphoglycerate Chemical compound [O-]P(=O)([O-])OC(C(=O)[O-])COP([O-])([O-])=O XOHUEYCVLUUEJJ-UHFFFAOYSA-I 0.000 claims 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 1
- 108010054147 Hemoglobins Proteins 0.000 claims 1
- 102000001554 Hemoglobins Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 108010064719 Oxyhemoglobins Proteins 0.000 claims 1
- 239000003463 adsorbent Substances 0.000 claims 1
- 229940098773 bovine serum albumin Drugs 0.000 claims 1
- 229910001424 calcium ion Inorganic materials 0.000 claims 1
- 238000006392 deoxygenation reaction Methods 0.000 claims 1
- 239000000385 dialysis solution Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2015/002331 | 2015-11-20 | ||
| PCT/EP2015/002331 WO2017084683A1 (en) | 2015-11-20 | 2015-11-20 | Method for extracorporeal lung support |
| PCT/EP2016/078198 WO2017085292A1 (en) | 2015-11-20 | 2016-11-18 | Method for extracorporeal lung support |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018538118A JP2018538118A (ja) | 2018-12-27 |
| JP2018538118A5 true JP2018538118A5 (enExample) | 2019-12-26 |
| JP6983793B2 JP6983793B2 (ja) | 2021-12-17 |
Family
ID=54608483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018545683A Active JP6983793B2 (ja) | 2015-11-20 | 2016-11-18 | 体外での肺補助のための方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11583620B2 (enExample) |
| EP (2) | EP4011416A1 (enExample) |
| JP (1) | JP6983793B2 (enExample) |
| KR (1) | KR102837618B1 (enExample) |
| CN (1) | CN108367109B (enExample) |
| AU (1) | AU2016356068B2 (enExample) |
| BR (1) | BR112018007200A2 (enExample) |
| CA (1) | CA3000927A1 (enExample) |
| DK (1) | DK3377139T3 (enExample) |
| ES (1) | ES2905621T3 (enExample) |
| IL (1) | IL258481B (enExample) |
| MX (1) | MX2018006089A (enExample) |
| PL (1) | PL3377139T3 (enExample) |
| WO (2) | WO2017084683A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| DK3429657T3 (da) | 2016-03-14 | 2022-06-13 | Advitos Gmbh | Systemer eller apparater til at udføre dialyse. |
| EP3634530B1 (en) * | 2017-05-22 | 2025-07-02 | ADVITOS GmbH | Methods and systems for removing carbon dioxide |
| BR112020004994A2 (pt) | 2017-09-17 | 2020-09-15 | Steven Paul Keller | sistemas, dispositivos e métodos para remoção extracorpórea de dióxido de carbono |
| CN108211032B (zh) | 2018-02-01 | 2023-11-17 | 南方医科大学珠江医院 | 组合型生物人工肝支持系统 |
| JP7301509B2 (ja) * | 2018-09-06 | 2023-07-03 | 聡 安斎 | 治療装置 |
| US11633525B2 (en) | 2019-01-29 | 2023-04-25 | Transonic Systems Inc. | Method and apparatus for assessing cardiac output in veno-arterial extracorporeal blood oxygenation |
| BR112021016857A2 (pt) * | 2019-02-26 | 2021-10-19 | Digital Blood Corporation | Sistema para exame não invasivo de parâmetros de ambiente sanguíneo de um usuário |
| US20220031921A1 (en) * | 2019-04-29 | 2022-02-03 | Verthermia Acquisition, Inc. | Method and System for Controlled Hyperthermia |
| US11065379B2 (en) * | 2019-04-30 | 2021-07-20 | Veryhermia Acquistion, Inc. | Method and system for controlled hyperthermia |
| EP4566535A3 (en) * | 2019-05-02 | 2025-06-25 | Transonic Systems Inc. | Calculating cardiac output of a patient undergoing veno-venous extracorporeal blood oxygenation |
| DE102019007144A1 (de) * | 2019-10-15 | 2021-04-15 | ProMedTec Germany GmbH | Verfahren und Anordnung zur Verbesserung des Austausches von Gasen über semipermeable Membranen im wässrigen Milieu |
| US20230166018A1 (en) * | 2020-04-07 | 2023-06-01 | Gis Ventures Inc. | Infusing dissolved oxygen into i.v. fluids to provide short term emergency oxygenation of venous blood for compromised or trauma patients |
| WO2022119951A1 (en) * | 2020-12-01 | 2022-06-09 | Boundless Science, Llc | Method and apparatus for enhanced transport |
| US11219551B1 (en) * | 2021-04-25 | 2022-01-11 | Verthermia Acquisition, Inc. | Method and system for controlled hyperthermia |
| WO2024024459A1 (ja) * | 2022-07-28 | 2024-02-01 | 国立大学法人 東京大学 | 血漿交換システム、及び血漿交換システムの制御方法 |
| JP2024064862A (ja) * | 2022-10-28 | 2024-05-14 | 株式会社ジェイ・エム・エス | 血液浄化システム及び中間システム |
Family Cites Families (52)
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|---|---|---|---|---|
| US4375414A (en) | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
| US3771658A (en) * | 1971-10-20 | 1973-11-13 | R Brumfield | Blood transport membrane pump |
| US3846236A (en) * | 1971-10-22 | 1974-11-05 | Wisconsin Alumni Res Found | Method and apparatus for dialysis |
| SE7403799L (enExample) | 1974-03-21 | 1975-09-22 | Gambro Ab | |
| DE3230540A1 (de) | 1982-08-17 | 1984-02-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Verfahren und vorrichtung zur entfernung von protein- oder lipidgebundenen toxinen aus blut oder blutfraktionen |
| US4663049A (en) | 1984-07-05 | 1987-05-05 | University Of Utah | Process for therapeutic dissociation of immune complexes and removal of antigens |
| IT8504923V0 (it) | 1985-06-07 | 1985-06-07 | Miren Srl | Dispositivo per il controllo del bilancio idrico di un paziente durante il trattamento di emodialisi |
| FR2651438A1 (fr) | 1989-09-07 | 1991-03-08 | Fondation Nale Transfusion San | Procede d'inactivation par ultrasons d'agents infectieux ou parasitaires dans des milieux biologiques et applications du procede. |
| US6344489B1 (en) | 1991-02-14 | 2002-02-05 | Wayne State University | Stabilized gas-enriched and gas-supersaturated liquids |
| DE4309410A1 (de) | 1993-03-19 | 1995-02-16 | Stange Jan | Material, Verfahren und Einrichtung zur selektiven Trennung frei gelöster und stoffgebundener Stoffe aus flüssigen Stoffgemischen sowie Verfahren zur Herstellung des Materials |
| US5753227A (en) | 1993-07-23 | 1998-05-19 | Strahilevitz; Meir | Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases |
| US5561115A (en) | 1994-08-10 | 1996-10-01 | Bayer Corporation | Low temperature albumin fractionation using sodium caprylate as a partitioning agent |
| US6607698B1 (en) * | 1997-08-15 | 2003-08-19 | Therox, Inc. | Method for generalized extracorporeal support |
| ATE283712T1 (de) | 1998-01-23 | 2004-12-15 | Viacirq Inc | Vorrichtung und verfahren zur ganzkörper- hyperthermiebehandlung |
| JP4061775B2 (ja) | 1998-05-21 | 2008-03-19 | ニプロ株式会社 | アルブミン含有腹膜透析液 |
| EP0980685B1 (en) | 1998-06-17 | 2006-01-25 | Nipro Corporation | Use of a fluid for the manufacture of a dialysis fluid for continuous recirculating peritoneal dialysis |
| JP2000072658A (ja) | 1998-06-17 | 2000-03-07 | Nissho Corp | 腹膜透析液および腹膜透析法 |
| DE19831061A1 (de) | 1998-07-10 | 2000-01-13 | Rotkreuzstiftung Zentrallab | Herstellung von Proteinpräparationen mit verringertem Aggregatgehalt |
| US7670491B2 (en) | 1998-10-20 | 2010-03-02 | Advanced Renal Technologies | Buffered compositions for dialysis |
| US6716356B2 (en) | 2000-01-11 | 2004-04-06 | Nephros, Inc. | Thermally enhanced dialysis/diafiltration system |
| WO2001051184A1 (en) | 2000-01-11 | 2001-07-19 | Nephros, Inc. | Ionic enhanced dialysis/diafiltration system |
| US7300674B2 (en) | 2000-12-20 | 2007-11-27 | Sheldon Tobe | Sterile low bicarbonate dialysis concentrate solutions |
| US7241272B2 (en) | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
| EP1362605A1 (de) | 2002-05-14 | 2003-11-19 | Bernhard Dr. Kreymann | Dialysevorrichtung zur Entfernung proteingebundener Substanzen |
| US7455771B2 (en) | 2002-05-14 | 2008-11-25 | Hepa Wash Gmbh | Means for removing protein-bound substances |
| US7112273B2 (en) | 2002-09-27 | 2006-09-26 | Nxstage Medical, Inc. | Volumetric fluid balance control for extracorporeal blood treatment |
| US7686778B2 (en) | 2003-01-15 | 2010-03-30 | Nxstage Medical, Inc. | Waste balancing for extracorporeal blood treatment systems |
| ITMI20030212A1 (it) | 2003-02-07 | 2004-08-08 | Gambro Lundia Ab | Metodo per il trattamento extracorporeo di sangue |
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| JP4903583B2 (ja) | 2003-12-24 | 2012-03-28 | ケミカ テクノロジーズ， インコーポレイテッド | 携帯式個人透析用透析液再生システム |
| FR2873925B1 (fr) * | 2004-08-05 | 2006-10-13 | Erytech Pharma Soc Par Actions | Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes |
| EP1649883A1 (en) | 2004-10-19 | 2006-04-26 | MRI S.r.l. Società Unipersonale | A CO2 removal device for removing carbon dioxide from blood or from a fluid taken from patient's cardio-circulatory system |
| JP4908044B2 (ja) | 2006-04-14 | 2012-04-04 | 株式会社ジェイ・エム・エス | 重量検出装置及びバランス制御装置 |
| US20090018484A1 (en) * | 2007-07-11 | 2009-01-15 | Levitov Alexander B | System device and method for oxygenation |
| US8377308B2 (en) | 2007-12-03 | 2013-02-19 | Hepa Wash Gmbh | Dialysate regeneration unit |
| DE102009008601A1 (de) | 2009-02-12 | 2010-08-19 | Novalung Gmbh | Vorrichtung zur Behandlung einer biologischen Flüssigkeit |
| PL2416770T3 (pl) | 2009-04-06 | 2017-06-30 | Crearene Ltd. | Roztwory do hemodializy i dializy otrzewnowej zawierające jeden lub więcej związków kreatyny |
| DK177144B1 (en) * | 2009-06-19 | 2012-02-06 | Aquaporin As | A liquid membrane suitable for water extraction |
| CN102107031A (zh) * | 2009-12-28 | 2011-06-29 | 天津市海河医院 | 血液血浆中毒素滤过吸附器及其制备方法和应用 |
| DE102010023635A1 (de) | 2010-06-14 | 2011-12-15 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Fördern von Flüssigkeiten in die Behandlungseinheit einer medizinischen Behandlungsvorrichtung, insbesondere in den Dialysator einer Dialysevorrichtung |
| JP2012228285A (ja) * | 2011-04-23 | 2012-11-22 | Sunceramics Corp | 酸素濃度を高めた透析液 |
| ES2532081T3 (es) | 2012-03-28 | 2015-03-24 | Gambro Lundia Ab | Aparato para tratamiento extracorpóreo de sangre |
| EP2653178A1 (de) | 2012-04-16 | 2013-10-23 | Zentrum für biomedizinische Technologie der Donau- Universität Krems | Sicherheitseinrichtung für eine extrakorporale Blutbehandlung |
| GB201207543D0 (en) * | 2012-05-01 | 2012-06-13 | Haemair Ltd | Treatment of transfusion blood |
| CN102940886B (zh) | 2012-12-13 | 2015-02-18 | 鼎正动物药业（天津）有限公司 | 一种生物屏障渗透剂及其制备方法 |
| US10322221B2 (en) | 2013-01-18 | 2019-06-18 | University of Pittsburgh—of the Commonwealth System of Higher Education | Removal of carbon dioxide via dialysis |
| WO2014160370A1 (en) | 2013-03-13 | 2014-10-02 | Nxstage Medical, Inc. | Single pass dialysis combined with multiple pass albumin dialysis |
| DE102013019356A1 (de) | 2013-11-19 | 2015-06-03 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zum Bilanzieren von Flüssigkeiten für eine extrakorporale Blutbehandlungsvorrichtung |
| WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
| WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
| EP3634530B1 (en) | 2017-05-22 | 2025-07-02 | ADVITOS GmbH | Methods and systems for removing carbon dioxide |
-
2015
- 2015-11-20 WO PCT/EP2015/002331 patent/WO2017084683A1/en not_active Ceased
-
2016
- 2016-11-18 CA CA3000927A patent/CA3000927A1/en active Pending
- 2016-11-18 KR KR1020187017421A patent/KR102837618B1/ko active Active
- 2016-11-18 PL PL16797952T patent/PL3377139T3/pl unknown
- 2016-11-18 BR BR112018007200A patent/BR112018007200A2/pt not_active Application Discontinuation
- 2016-11-18 ES ES16797952T patent/ES2905621T3/es active Active
- 2016-11-18 EP EP21207826.5A patent/EP4011416A1/en not_active Withdrawn
- 2016-11-18 MX MX2018006089A patent/MX2018006089A/es unknown
- 2016-11-18 CN CN201680063827.4A patent/CN108367109B/zh active Active
- 2016-11-18 EP EP16797952.5A patent/EP3377139B1/en active Active
- 2016-11-18 WO PCT/EP2016/078198 patent/WO2017085292A1/en not_active Ceased
- 2016-11-18 US US15/777,639 patent/US11583620B2/en active Active
- 2016-11-18 DK DK16797952.5T patent/DK3377139T3/da active
- 2016-11-18 AU AU2016356068A patent/AU2016356068B2/en not_active Ceased
- 2016-11-18 JP JP2018545683A patent/JP6983793B2/ja active Active
-
2018
- 2018-04-02 IL IL258481A patent/IL258481B/en unknown
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