JP2018536697A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018536697A5 JP2018536697A5 JP2018534025A JP2018534025A JP2018536697A5 JP 2018536697 A5 JP2018536697 A5 JP 2018536697A5 JP 2018534025 A JP2018534025 A JP 2018534025A JP 2018534025 A JP2018534025 A JP 2018534025A JP 2018536697 A5 JP2018536697 A5 JP 2018536697A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- disease
- composition according
- protein
- homeoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 230000005778 DNA damage Effects 0.000 claims 6
- 231100000277 DNA damage Toxicity 0.000 claims 6
- 102000009331 Homeodomain Proteins Human genes 0.000 claims 6
- 108010048671 Homeodomain Proteins Proteins 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 208000015122 neurodegenerative disease Diseases 0.000 claims 4
- 208000023105 Huntington disease Diseases 0.000 claims 3
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000018737 Parkinson disease Diseases 0.000 claims 2
- 101150000168 lhx9 gene Proteins 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 210000005069 ears Anatomy 0.000 claims 1
- 230000004770 neurodegeneration Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15306482 | 2015-09-23 | ||
| EP15306482.9 | 2015-09-23 | ||
| PCT/EP2016/072675 WO2017071889A1 (en) | 2015-09-23 | 2016-09-23 | Homeoproteins for use in the treatment of neurodegenerative disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018536697A JP2018536697A (ja) | 2018-12-13 |
| JP2018536697A5 true JP2018536697A5 (cg-RX-API-DMAC7.html) | 2019-09-05 |
| JP6860575B2 JP6860575B2 (ja) | 2021-04-14 |
Family
ID=54207439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018534025A Active JP6860575B2 (ja) | 2015-09-23 | 2016-09-23 | 神経変性障害の処置に用いられるホメオタンパク質 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20190247461A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3960195B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6860575B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN108289929A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2999209A1 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2895154T3 (cg-RX-API-DMAC7.html) |
| PL (2) | PL3960195T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017071889A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024149784A1 (en) | 2023-01-13 | 2024-07-18 | Brainever | Stabilized engrailed protein aqueous compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2662698A1 (fr) * | 1990-06-05 | 1991-12-06 | Centre Nat Rech Scient | Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite. |
| FR2855178B1 (fr) * | 2003-05-20 | 2005-08-05 | Centre Nat Rech Scient | Peptides modulateurs de l'activite du facteur de transcription engrailed |
| FR2897780B1 (fr) | 2006-02-28 | 2008-05-23 | Centre Nat Rech Scient | Utilisation de la proteine a homeodomaine engrailed comme anxiolytique |
| GB0625321D0 (en) * | 2006-12-19 | 2007-01-24 | Univ Surrey | Cancer biomarker |
| FR2926023B1 (fr) | 2008-01-09 | 2010-02-26 | Centre Nat Rech Scient | Utilisation d'une homoproteine de la famille bicoid pour le traitement du glaucome. |
| EP2454597A1 (en) * | 2009-07-13 | 2012-05-23 | The University of Surrey | Therapeutic peptides, polypeptides ans nucleic acid sequences |
| WO2013128239A1 (en) | 2012-02-29 | 2013-09-06 | Centre National De La Recherche Scientifique | Use of engrailed for increasing dopamine synthesis by dopaminergic neurons |
-
2016
- 2016-09-23 US US15/761,702 patent/US20190247461A1/en not_active Abandoned
- 2016-09-23 WO PCT/EP2016/072675 patent/WO2017071889A1/en not_active Ceased
- 2016-09-23 CN CN201680059070.1A patent/CN108289929A/zh active Pending
- 2016-09-23 PL PL21189549.5T patent/PL3960195T3/pl unknown
- 2016-09-23 ES ES16777596T patent/ES2895154T3/es active Active
- 2016-09-23 ES ES21189549T patent/ES3010130T3/es active Active
- 2016-09-23 CA CA2999209A patent/CA2999209A1/en active Pending
- 2016-09-23 EP EP21189549.5A patent/EP3960195B1/en active Active
- 2016-09-23 JP JP2018534025A patent/JP6860575B2/ja active Active
- 2016-09-23 PL PL16777596T patent/PL3352777T3/pl unknown
- 2016-09-23 EP EP16777596.4A patent/EP3352777B1/en active Active
-
2021
- 2021-06-16 US US17/349,746 patent/US20210379144A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019524822A5 (cg-RX-API-DMAC7.html) | ||
| WO2017070647A8 (en) | Nicotinamide for use in the treatment and prevention of ocular neurodegenerative disorder (e.g. glaucoma) | |
| HRP20191055T1 (hr) | Terapeutska sredstva za neurodegenerativne bolesti | |
| WO2012080729A3 (en) | Casein kinase 1delta (ck1delta) inhibitors and their use in the treatment of neurodegenerative diseases such as tauopathies | |
| MX2018008557A (es) | Anticuerpos peptidicos beta amiloide anti-n3pglu y usos de los mismos. | |
| AU2018264384A1 (en) | Solid forms of berberine ursodeoxycholate and compositions and methods thereof | |
| WO2018060732A3 (en) | Compositions and methods for treating seizure disorders | |
| EP3405215A4 (en) | METHOD FOR THE TREATMENT OF MORBUS DANON AND OTHER AUTOPHAGIC DISEASES | |
| WO2014178931A8 (en) | Sobetirome in the treatment of myelination diseases | |
| SG11201705986QA (en) | Antibody molecules and peptide delivery systems for use in alzheimer's disease and related disorders | |
| EA201991756A1 (ru) | Бисгетероарильные производные в качестве модуляторов агрегации белков | |
| WO2017062468A8 (en) | Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof | |
| MX2018004109A (es) | Activadores de flujo autofágico y fosfolipasa d y depuración de acumulaciones de proteína que incluyen tau y tratamiento de proteinopatías. | |
| IL278813A (en) | Gene therapy for Alzheimer's disease | |
| HK1210598A1 (en) | Di-and tri-heteroaryl derivatives as inhibitors of protein aggregation | |
| BR112017011226A2 (pt) | peptídeo, composição farmacêutica, processo para fabricação da composição farmacêutica | |
| EP3982819A4 (en) | METHODS FOR EVALUATION AND TREATMENT OF ALZHEIMER'S DISEASE AND APPLICATIONS THEREOF | |
| HRP20210361T1 (hr) | Upotreba pripravka koji sadrži gliceril-tribenzoat kod neurodegenerativnih poremećaja | |
| IL259710A (en) | Compositions and methods of treatment for mvid and related diseases | |
| JP2016523969A5 (cg-RX-API-DMAC7.html) | ||
| EA201991753A1 (ru) | Алкоксибисгетероарильные производные в качестве модуляторов агрегации белков | |
| JP2018536697A5 (cg-RX-API-DMAC7.html) | ||
| WO2019070727A3 (en) | Nonviral gene transfer to the suprachoroidal space | |
| PH12021550090A1 (en) | Composition comprising glycyrrhizin and cosmetic and pharmaceutical uses thereof | |
| WO2017079161A3 (en) | Treatment of neurodegenerative disease with sodium chlorite |