CA2999209A1 - Homeoproteins for use in the treatment of neurodegenerative disorders - Google Patents

Homeoproteins for use in the treatment of neurodegenerative disorders Download PDF

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Publication number
CA2999209A1
CA2999209A1 CA2999209A CA2999209A CA2999209A1 CA 2999209 A1 CA2999209 A1 CA 2999209A1 CA 2999209 A CA2999209 A CA 2999209A CA 2999209 A CA2999209 A CA 2999209A CA 2999209 A1 CA2999209 A1 CA 2999209A1
Authority
CA
Canada
Prior art keywords
homeoprotein
neurons
dna
disease
mice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2999209A
Other languages
English (en)
French (fr)
Inventor
Alain Prochiantz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Sorbonne Universite
College de France
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut National de la Sante et de la Recherche Medicale INSERM
Sorbonne Universite
College de France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut National de la Sante et de la Recherche Medicale INSERM, Sorbonne Universite, College de France filed Critical Centre National de la Recherche Scientifique CNRS
Publication of CA2999209A1 publication Critical patent/CA2999209A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2999209A 2015-09-23 2016-09-23 Homeoproteins for use in the treatment of neurodegenerative disorders Pending CA2999209A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15306482 2015-09-23
EP15306482.9 2015-09-23
PCT/EP2016/072675 WO2017071889A1 (en) 2015-09-23 2016-09-23 Homeoproteins for use in the treatment of neurodegenerative disorders

Publications (1)

Publication Number Publication Date
CA2999209A1 true CA2999209A1 (en) 2017-05-04

Family

ID=54207439

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2999209A Pending CA2999209A1 (en) 2015-09-23 2016-09-23 Homeoproteins for use in the treatment of neurodegenerative disorders

Country Status (8)

Country Link
US (2) US20190247461A1 (cg-RX-API-DMAC7.html)
EP (2) EP3960195B1 (cg-RX-API-DMAC7.html)
JP (1) JP6860575B2 (cg-RX-API-DMAC7.html)
CN (1) CN108289929A (cg-RX-API-DMAC7.html)
CA (1) CA2999209A1 (cg-RX-API-DMAC7.html)
ES (2) ES2895154T3 (cg-RX-API-DMAC7.html)
PL (2) PL3960195T3 (cg-RX-API-DMAC7.html)
WO (1) WO2017071889A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024149784A1 (en) 2023-01-13 2024-07-18 Brainever Stabilized engrailed protein aqueous compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662698A1 (fr) * 1990-06-05 1991-12-06 Centre Nat Rech Scient Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite.
FR2855178B1 (fr) * 2003-05-20 2005-08-05 Centre Nat Rech Scient Peptides modulateurs de l'activite du facteur de transcription engrailed
FR2897780B1 (fr) 2006-02-28 2008-05-23 Centre Nat Rech Scient Utilisation de la proteine a homeodomaine engrailed comme anxiolytique
GB0625321D0 (en) * 2006-12-19 2007-01-24 Univ Surrey Cancer biomarker
FR2926023B1 (fr) 2008-01-09 2010-02-26 Centre Nat Rech Scient Utilisation d'une homoproteine de la famille bicoid pour le traitement du glaucome.
EP2454597A1 (en) * 2009-07-13 2012-05-23 The University of Surrey Therapeutic peptides, polypeptides ans nucleic acid sequences
WO2013128239A1 (en) 2012-02-29 2013-09-06 Centre National De La Recherche Scientifique Use of engrailed for increasing dopamine synthesis by dopaminergic neurons

Also Published As

Publication number Publication date
US20210379144A1 (en) 2021-12-09
ES3010130T3 (en) 2025-04-01
EP3352777B1 (en) 2021-09-15
JP6860575B2 (ja) 2021-04-14
JP2018536697A (ja) 2018-12-13
PL3352777T3 (pl) 2022-02-07
EP3960195B1 (en) 2025-01-08
PL3960195T3 (pl) 2025-06-09
WO2017071889A1 (en) 2017-05-04
EP3352777A1 (en) 2018-08-01
US20190247461A1 (en) 2019-08-15
EP3960195A1 (en) 2022-03-02
CN108289929A (zh) 2018-07-17
ES2895154T3 (es) 2022-02-17

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