JP2018534245A - 調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法 - Google Patents
調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法 Download PDFInfo
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- JP2018534245A JP2018534245A JP2018513462A JP2018513462A JP2018534245A JP 2018534245 A JP2018534245 A JP 2018534245A JP 2018513462 A JP2018513462 A JP 2018513462A JP 2018513462 A JP2018513462 A JP 2018513462A JP 2018534245 A JP2018534245 A JP 2018534245A
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562218531P | 2015-09-14 | 2015-09-14 | |
| US62/218,531 | 2015-09-14 | ||
| US201662323595P | 2016-04-15 | 2016-04-15 | |
| US201662323608P | 2016-04-15 | 2016-04-15 | |
| US62/323,595 | 2016-04-15 | ||
| US62/323,608 | 2016-04-15 | ||
| US201662367819P | 2016-07-28 | 2016-07-28 | |
| US201662367822P | 2016-07-28 | 2016-07-28 | |
| US62/367,819 | 2016-07-28 | ||
| US62/367,822 | 2016-07-28 | ||
| PCT/US2016/051786 WO2017048878A1 (en) | 2015-09-14 | 2016-09-14 | Tunable variant immunoglobulin superfamily domains and engineered cell therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018534245A true JP2018534245A (ja) | 2018-11-22 |
| JP2018534245A5 JP2018534245A5 (enExample) | 2019-10-24 |
Family
ID=57068203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018513462A Pending JP2018534245A (ja) | 2015-09-14 | 2016-09-14 | 調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180256644A1 (enExample) |
| EP (1) | EP3350206A1 (enExample) |
| JP (1) | JP2018534245A (enExample) |
| KR (1) | KR20180054713A (enExample) |
| CN (1) | CN108513576A (enExample) |
| AU (1) | AU2016323069A1 (enExample) |
| BR (1) | BR112018004965A2 (enExample) |
| CA (1) | CA2997217A1 (enExample) |
| EA (1) | EA201890729A1 (enExample) |
| IL (1) | IL258102A (enExample) |
| MX (1) | MX2018003144A (enExample) |
| WO (1) | WO2017048878A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113045660B (zh) | 2013-03-13 | 2023-09-01 | 伊麦吉纳博公司 | 与cd8的抗原结合构建体 |
| EP3283508B1 (en) | 2015-04-17 | 2021-03-17 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins with tunable affinities |
| ES3020458T3 (en) | 2015-08-07 | 2025-05-22 | Imaginab Inc | Antigen binding constructs to target molecules |
| MA43163A (fr) | 2015-11-02 | 2018-09-12 | Five Prime Therapeutics Inc | Polypeptides à domaine extracellulaire cd80 et leur utilisation dans le traitement du cancer |
| EP3443000B1 (en) | 2016-04-15 | 2025-11-12 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| KR102824067B1 (ko) | 2016-04-15 | 2025-06-23 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Icos 리간드 변이체 면역조절 단백질 및 그의 용도 |
| US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
| US11834490B2 (en) | 2016-07-28 | 2023-12-05 | Alpine Immune Sciences, Inc. | CD112 variant immunomodulatory proteins and uses thereof |
| AU2017345764A1 (en) * | 2016-10-20 | 2019-05-02 | Alpine Immune Sciences, Inc. | Secretable variant immunomodulatory proteins and engineered cell therapy |
| CA3054068A1 (en) | 2017-03-16 | 2018-09-20 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| CN110809581A (zh) | 2017-03-16 | 2020-02-18 | 高山免疫科学股份有限公司 | Pd-l2变体免疫调节蛋白及其用途 |
| JP2020517913A (ja) | 2017-04-28 | 2020-06-18 | ファイブ プライム セラピューティクス, インコーポレイテッド | Cd80細胞外ドメインポリペプチドによる治療方法 |
| UA128472C2 (uk) | 2017-08-25 | 2024-07-24 | Файв Прайм Терапеутікс Інк. | B7-h4 антитіла і методи їх використання |
| KR102813968B1 (ko) | 2017-10-10 | 2025-05-29 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Ctla-4 변이체 면역조절 단백질 및 이의 용도 |
| MX2020004540A (es) * | 2017-10-18 | 2020-08-03 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras de ligando icos variante y composiciones y metodos relacionados. |
| EP3735417A1 (en) * | 2018-01-03 | 2020-11-11 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| BR112020016986A2 (pt) | 2018-02-21 | 2021-03-02 | Five Prime Therapeutics, Inc. | formulações de anticorpo contra b7-h4 |
| CA3091801A1 (en) | 2018-03-02 | 2019-09-06 | Five Prime Therapeutics, Inc. | B7-h4 antibodies and methods of use thereof |
| WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
| AU2019324170A1 (en) | 2018-08-23 | 2021-02-18 | Seagen, Inc. | Anti-TIGIT antibodies |
| JP7315703B2 (ja) * | 2018-12-24 | 2023-07-26 | ▲海▼▲東▼ 黄 | 組み換えヒト2Ig-B7-H3タンパク質コーディング遺伝子、組換えベクター及びそれを含む宿主細胞、並びに薬物組成物及びその応用 |
| EP3908372A1 (en) * | 2019-01-13 | 2021-11-17 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Antibodies specific to human nectin-2 |
| US12378299B2 (en) * | 2019-04-26 | 2025-08-05 | Xuanzhu Biopharmaceutical Co., Ltd. | CD80 variant proteins and uses thereof |
| PH12021552979A1 (en) | 2019-05-27 | 2023-10-09 | Immatics Us Inc | Viral vectors and their use in adoptive cellular therapy |
| WO2021050789A1 (en) | 2019-09-10 | 2021-03-18 | Obsidian Therapeutics, Inc. | Ca2-il15 fusion proteins for tunable regulation |
| CN110859951A (zh) * | 2019-09-23 | 2020-03-06 | 中国药科大学 | Cd200蛋白和cd200融合蛋白在制备治疗银屑病药物中的应用 |
| CN113087806B (zh) * | 2019-12-31 | 2022-09-06 | 华东师范大学 | 靶向多种肿瘤的新型car-t细胞及其制备和方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH09202800A (ja) * | 1995-07-21 | 1997-08-05 | Bristol Myers Squibb Co | Ctla4変異体分子およびそれの使用 |
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| US7183376B2 (en) * | 2000-06-23 | 2007-02-27 | Maxygen, Inc. | Variant B7 co-stimulatory molecules |
| PT2856876T (pt) * | 2007-03-30 | 2018-03-28 | Memorial Sloan Kettering Cancer Center | Expressão constitutiva de ligantes co-estimulatórios em linfócitos t adotivamente transferidos |
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2016
- 2016-09-14 EA EA201890729A patent/EA201890729A1/ru unknown
- 2016-09-14 WO PCT/US2016/051786 patent/WO2017048878A1/en not_active Ceased
- 2016-09-14 BR BR112018004965A patent/BR112018004965A2/pt not_active IP Right Cessation
- 2016-09-14 AU AU2016323069A patent/AU2016323069A1/en not_active Abandoned
- 2016-09-14 KR KR1020187010556A patent/KR20180054713A/ko not_active Withdrawn
- 2016-09-14 CN CN201680066217.XA patent/CN108513576A/zh active Pending
- 2016-09-14 EP EP16775919.0A patent/EP3350206A1/en not_active Withdrawn
- 2016-09-14 CA CA2997217A patent/CA2997217A1/en not_active Abandoned
- 2016-09-14 US US15/759,812 patent/US20180256644A1/en not_active Abandoned
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- 2016-09-14 JP JP2018513462A patent/JP2018534245A/ja active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3350206A1 (en) | 2018-07-25 |
| EA201890729A1 (ru) | 2018-09-28 |
| WO2017048878A1 (en) | 2017-03-23 |
| CA2997217A1 (en) | 2017-03-23 |
| KR20180054713A (ko) | 2018-05-24 |
| BR112018004965A2 (pt) | 2018-10-09 |
| AU2016323069A1 (en) | 2018-04-12 |
| MX2018003144A (es) | 2018-09-11 |
| US20180256644A1 (en) | 2018-09-13 |
| IL258102A (en) | 2018-05-31 |
| CN108513576A (zh) | 2018-09-07 |
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