JP2018534245A - 調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法 - Google Patents
調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法 Download PDFInfo
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- JP2018534245A JP2018534245A JP2018513462A JP2018513462A JP2018534245A JP 2018534245 A JP2018534245 A JP 2018534245A JP 2018513462 A JP2018513462 A JP 2018513462A JP 2018513462 A JP2018513462 A JP 2018513462A JP 2018534245 A JP2018534245 A JP 2018534245A
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562218531P | 2015-09-14 | 2015-09-14 | |
| US62/218,531 | 2015-09-14 | ||
| US201662323595P | 2016-04-15 | 2016-04-15 | |
| US201662323608P | 2016-04-15 | 2016-04-15 | |
| US62/323,595 | 2016-04-15 | ||
| US62/323,608 | 2016-04-15 | ||
| US201662367819P | 2016-07-28 | 2016-07-28 | |
| US201662367822P | 2016-07-28 | 2016-07-28 | |
| US62/367,819 | 2016-07-28 | ||
| US62/367,822 | 2016-07-28 | ||
| PCT/US2016/051786 WO2017048878A1 (en) | 2015-09-14 | 2016-09-14 | Tunable variant immunoglobulin superfamily domains and engineered cell therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018534245A true JP2018534245A (ja) | 2018-11-22 |
| JP2018534245A5 JP2018534245A5 (cg-RX-API-DMAC7.html) | 2019-10-24 |
Family
ID=57068203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018513462A Pending JP2018534245A (ja) | 2015-09-14 | 2016-09-14 | 調整可能なバリアント免疫グロブリンスーパーファミリードメインおよび改変細胞療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180256644A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3350206A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2018534245A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20180054713A (cg-RX-API-DMAC7.html) |
| CN (1) | CN108513576A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016323069A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112018004965A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2997217A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201890729A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL258102A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2018003144A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017048878A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105163765A (zh) | 2013-03-13 | 2015-12-16 | 伊麦吉纳博公司 | 与cd8的抗原结合构建体 |
| SI3283508T1 (sl) | 2015-04-17 | 2021-09-30 | Alpine Immune Sciences, Inc. | Imunomodulirajoči proteini z nastavljivimi afinitetami |
| AU2016304764C1 (en) | 2015-08-07 | 2023-06-01 | Imaginab, Inc. | Antigen binding constructs to target molecules |
| PE20181300A1 (es) | 2015-11-02 | 2018-08-09 | Five Prime Therapeutics Inc | Polipeptidos del dominio extracelular de cd80 y su uso en el tratamiento del cancer |
| SG11201808457PA (en) * | 2016-04-15 | 2018-10-30 | Alpine Immune Sciences Inc | Icos ligand variant immunomodulatory proteins and uses thereof |
| WO2017181152A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| WO2018022945A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd112 variant immunomodulatory proteins and uses thereof |
| US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
| AU2017345764A1 (en) * | 2016-10-20 | 2019-05-02 | Alpine Immune Sciences, Inc. | Secretable variant immunomodulatory proteins and engineered cell therapy |
| WO2018170026A2 (en) | 2017-03-16 | 2018-09-20 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| CA3053812A1 (en) | 2017-03-16 | 2018-09-20 | Alpine Immune Sciences, Inc. | Pd-l2 variant immunomodulatory proteins and uses thereof |
| EA201992586A1 (ru) | 2017-04-28 | 2020-03-03 | Файв Прайм Терапьютикс, Инк. | Способы лечения с помощью полипептидов внеклеточного домена cd80 |
| CA3070774A1 (en) | 2017-08-25 | 2019-02-28 | Five Prime Therapeutics, Inc. | B7-h4 antibodies and methods of use thereof |
| EP3694870A1 (en) | 2017-10-10 | 2020-08-19 | Alpine Immune Sciences, Inc. | Ctla-4 variant immunomodulatory proteins and uses thereof |
| MY203416A (en) * | 2017-10-18 | 2024-06-27 | Alpine Immune Sciences Inc | Variant icos ligand immunomodulatory proteins and related compositions and methods |
| BR112020013236A2 (pt) * | 2018-01-03 | 2020-12-01 | Alpine Immune Sciences, Inc. | proteínas imunomoduladoras de múltiplos domínios e métodos de seu uso |
| CA3091174A1 (en) | 2018-02-21 | 2019-08-29 | Five Prime Therapeutics, Inc. | B7-h4 antibody formulations |
| EA202091810A1 (ru) | 2018-03-02 | 2021-01-29 | Файв Прайм Терапьютикс, Инк. | Антитела к b7-h4 и способы их применения |
| WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
| US11401339B2 (en) | 2018-08-23 | 2022-08-02 | Seagen Inc. | Anti-TIGIT antibodies |
| WO2020132789A1 (zh) * | 2018-12-24 | 2020-07-02 | 黄海东 | 突变的人2Ig-B7-H3蛋白编码基因、重组载体、包含其的宿主细胞、药物组合物及其应用 |
| CA3125962A1 (en) * | 2019-01-13 | 2020-07-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Antibodies specific to human nectin-2 |
| WO2020219896A1 (en) * | 2019-04-26 | 2020-10-29 | Beijing Xuanyi Pharmasciences Co., Ltd. | Cd80 variant proteins and uses thereof |
| TWI872076B (zh) | 2019-05-27 | 2025-02-11 | 美商英麥提克斯股份有限公司 | 病毒載體及其在授受性細胞療法之應用 |
| CN114651003A (zh) | 2019-09-10 | 2022-06-21 | 黑曜石疗法公司 | 用于可调调节的ca2-il15融合蛋白 |
| CN110859951A (zh) * | 2019-09-23 | 2020-03-06 | 中国药科大学 | Cd200蛋白和cd200融合蛋白在制备治疗银屑病药物中的应用 |
| CN113087806B (zh) * | 2019-12-31 | 2022-09-06 | 华东师范大学 | 靶向多种肿瘤的新型car-t细胞及其制备和方法 |
Citations (7)
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| JPH09202800A (ja) * | 1995-07-21 | 1997-08-05 | Bristol Myers Squibb Co | Ctla4変異体分子およびそれの使用 |
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| US7183376B2 (en) * | 2000-06-23 | 2007-02-27 | Maxygen, Inc. | Variant B7 co-stimulatory molecules |
| US8389282B2 (en) * | 2007-03-30 | 2013-03-05 | Memorial Sloan-Kettering Cancer Center | Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes |
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2016
- 2016-09-14 JP JP2018513462A patent/JP2018534245A/ja active Pending
- 2016-09-14 CA CA2997217A patent/CA2997217A1/en not_active Abandoned
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- 2016-09-14 AU AU2016323069A patent/AU2016323069A1/en not_active Abandoned
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- 2016-09-14 KR KR1020187010556A patent/KR20180054713A/ko not_active Withdrawn
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|---|---|
| BR112018004965A2 (pt) | 2018-10-09 |
| US20180256644A1 (en) | 2018-09-13 |
| CN108513576A (zh) | 2018-09-07 |
| KR20180054713A (ko) | 2018-05-24 |
| AU2016323069A1 (en) | 2018-04-12 |
| CA2997217A1 (en) | 2017-03-23 |
| MX2018003144A (es) | 2018-09-11 |
| EA201890729A1 (ru) | 2018-09-28 |
| IL258102A (en) | 2018-05-31 |
| EP3350206A1 (en) | 2018-07-25 |
| WO2017048878A1 (en) | 2017-03-23 |
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