JP2018531967A5 - - Google Patents
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- Publication number
- JP2018531967A5 JP2018531967A5 JP2018521655A JP2018521655A JP2018531967A5 JP 2018531967 A5 JP2018531967 A5 JP 2018531967A5 JP 2018521655 A JP2018521655 A JP 2018521655A JP 2018521655 A JP2018521655 A JP 2018521655A JP 2018531967 A5 JP2018531967 A5 JP 2018531967A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- disease
- compound
- disorder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 206010002022 amyloidosis Diseases 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
- 230000009286 beneficial effect Effects 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000022256 primary systemic amyloidosis Diseases 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1518950.9 | 2015-10-27 | ||
| GBGB1518950.9A GB201518950D0 (en) | 2015-10-27 | 2015-10-27 | Compound |
| PCT/EP2016/075632 WO2017072099A1 (en) | 2015-10-27 | 2016-10-25 | D-proline derivatives as sap depleting agent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020182835A Division JP7053762B2 (ja) | 2015-10-27 | 2020-10-30 | Ｓａｐ枯渇剤としてのｄ－プロリン誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018531967A JP2018531967A (ja) | 2018-11-01 |
| JP2018531967A5 true JP2018531967A5 (https=) | 2019-12-05 |
| JP6789288B2 JP6789288B2 (ja) | 2020-11-25 |
Family
ID=55130261
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018521655A Expired - Fee Related JP6789288B2 (ja) | 2015-10-27 | 2016-10-25 | Ｓａｐ枯渇剤としてのｄ−プロリン誘導体 |
| JP2020182835A Expired - Fee Related JP7053762B2 (ja) | 2015-10-27 | 2020-10-30 | Ｓａｐ枯渇剤としてのｄ－プロリン誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020182835A Expired - Fee Related JP7053762B2 (ja) | 2015-10-27 | 2020-10-30 | Ｓａｐ枯渇剤としてのｄ－プロリン誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10328052B2 (https=) |
| EP (1) | EP3368532B1 (https=) |
| JP (2) | JP6789288B2 (https=) |
| KR (1) | KR20180067559A (https=) |
| CN (1) | CN108368095B (https=) |
| AU (1) | AU2016345462A1 (https=) |
| BR (1) | BR112018008582A2 (https=) |
| CA (1) | CA3002710A1 (https=) |
| ES (1) | ES2781550T3 (https=) |
| GB (1) | GB201518950D0 (https=) |
| RU (1) | RU2018119120A (https=) |
| WO (1) | WO2017072099A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202111866D0 (en) | 2021-08-18 | 2021-09-29 | Ucl Business Plc | Prodrugs for use in the treatment of tissue damage |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
| EP0915088B1 (en) * | 1997-10-31 | 2002-09-18 | F. Hoffmann-La Roche Ag | D-Proline derivatives |
| US6903129B2 (en) * | 2001-12-14 | 2005-06-07 | Hoffman-La Roche Inc. | D-proline prodrugs |
| US7265140B2 (en) * | 2003-09-23 | 2007-09-04 | Pfizer Inc | Acyloxymethylcarbamate prodrugs of oxazolidinones |
| US8236792B2 (en) * | 2008-05-23 | 2012-08-07 | Janssen Pharmaceutica Nv | Substituted pyrrolidine amides as modulators of the histamine H3 receptor |
| GB201407506D0 (en) | 2014-04-29 | 2014-06-11 | Glaxosmithkline Ip Dev Ltd | Novel compound |
| US9737505B2 (en) | 2014-04-29 | 2017-08-22 | Glaxosmithkline Intellectual Property Development Limited | Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
-
2015
- 2015-10-27 GB GBGB1518950.9A patent/GB201518950D0/en not_active Ceased
-
2016
- 2016-10-25 KR KR1020187011871A patent/KR20180067559A/ko not_active Withdrawn
- 2016-10-25 CA CA3002710A patent/CA3002710A1/en not_active Abandoned
- 2016-10-25 ES ES16823162T patent/ES2781550T3/es active Active
- 2016-10-25 EP EP16823162.9A patent/EP3368532B1/en active Active
- 2016-10-25 BR BR112018008582A patent/BR112018008582A2/pt not_active Application Discontinuation
- 2016-10-25 RU RU2018119120A patent/RU2018119120A/ru not_active Application Discontinuation
- 2016-10-25 CN CN201680073108.0A patent/CN108368095B/zh not_active Expired - Fee Related
- 2016-10-25 US US15/771,442 patent/US10328052B2/en active Active
- 2016-10-25 JP JP2018521655A patent/JP6789288B2/ja not_active Expired - Fee Related
- 2016-10-25 AU AU2016345462A patent/AU2016345462A1/en not_active Abandoned
- 2016-10-25 WO PCT/EP2016/075632 patent/WO2017072099A1/en not_active Ceased
-
2020
- 2020-10-30 JP JP2020182835A patent/JP7053762B2/ja not_active Expired - Fee Related
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