JP2018529346A - 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２ - Google Patents

免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２ Download PDF

Info

Publication number
JP2018529346A
JP2018529346A JP2018515530A JP2018515530A JP2018529346A JP 2018529346 A JP2018529346 A JP 2018529346A JP 2018515530 A JP2018515530 A JP 2018515530A JP 2018515530 A JP2018515530 A JP 2018515530A JP 2018529346 A JP2018529346 A JP 2018529346A
Authority
JP
Japan
Prior art keywords
monocytes
seq
cells
cpg
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2018515530A
Other languages
English (en)
Japanese (ja)
Other versions
JP2018529346A5 (https=
Inventor
オレク，スフェン
Original Assignee
エピオンティス ゲーエムベーハー
エピオンティス ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エピオンティス ゲーエムベーハー, エピオンティス ゲーエムベーハー filed Critical エピオンティス ゲーエムベーハー
Publication of JP2018529346A publication Critical patent/JP2018529346A/ja
Publication of JP2018529346A5 publication Critical patent/JP2018529346A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Mechanical Control Devices (AREA)
JP2018515530A 2015-09-25 2016-09-22 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２ Pending JP2018529346A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1516975.8A GB201516975D0 (en) 2015-09-25 2015-09-25 PARK2 as epigenetic marker for the identification of immune cells, in particular monocytes
GB1516975.8 2015-09-25
PCT/EP2016/072594 WO2017050925A1 (en) 2015-09-25 2016-09-22 Park2 as epigenetic marker for the identification of immune cells, in particular monocytes

Publications (2)

Publication Number Publication Date
JP2018529346A true JP2018529346A (ja) 2018-10-11
JP2018529346A5 JP2018529346A5 (https=) 2019-10-31

Family

ID=54544104

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018515530A Pending JP2018529346A (ja) 2015-09-25 2016-09-22 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２

Country Status (7)

Country Link
US (1) US11761041B2 (https=)
EP (1) EP3353319B1 (https=)
JP (1) JP2018529346A (https=)
CN (2) CN108026590B (https=)
CA (1) CA2999614C (https=)
GB (1) GB201516975D0 (https=)
WO (1) WO2017050925A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022191293A1 (ja) * 2021-03-12 2022-09-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 全単球及びｃｄ１６陽性単球の割合の測定方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017125013B4 (de) * 2017-10-25 2019-10-17 Epiontis Gmbh MCC als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere basophiler Granulozyten
DE102017125150B4 (de) * 2017-10-26 2019-10-10 Epiontis Gmbh Endosialin (CD248) als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere naïver CD8+ T-Zellen
DE102017125335B4 (de) 2017-10-27 2019-10-17 Epiontis Gmbh Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten
HK1256212A2 (zh) * 2018-12-27 2019-09-13 汪恩光 拉动式的换挡传动系统及食物料理机

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014170497A2 (en) * 2013-04-19 2014-10-23 Epiontis Gmbh Method for identifying the quantitative cellular composition in a biological sample

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2367012T3 (es) * 2006-02-28 2011-10-27 Charite-Universitätsmedizin Berlin Detección y control de calidad de linfocitos t reguladores a través del análisis de metilación del adn del gen foxp3.
CA2671270A1 (en) * 2006-12-29 2008-07-17 Asuragen, Inc. Mir-16 regulated genes and pathways as targets for therapeutic intervention
PL2248913T3 (pl) * 2009-04-28 2017-04-28 Epiontis Gmbh GNLY jako marker epigenetyczny do identyfikacji komórek naturalnej cytotoksyczności ekspresjonujących CD56
WO2011128820A2 (en) * 2010-04-16 2011-10-20 Koninklijke Philips Electronics N.V. Methods for the analysis of breast cancer disorders
WO2013033627A2 (en) * 2011-09-01 2013-03-07 The Regents Of The University Of California Diagnosis and treatment of arthritis using epigenetics
WO2013067451A2 (en) * 2011-11-04 2013-05-10 Population Diagnostics Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014170497A2 (en) * 2013-04-19 2014-10-23 Epiontis Gmbh Method for identifying the quantitative cellular composition in a biological sample

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022191293A1 (ja) * 2021-03-12 2022-09-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 全単球及びｃｄ１６陽性単球の割合の測定方法
JPWO2022191293A1 (https=) * 2021-03-12 2022-09-15

Also Published As

Publication number Publication date
HK1257582A1 (en) 2019-10-25
US11761041B2 (en) 2023-09-19
WO2017050925A1 (en) 2017-03-30
EP3353319A1 (en) 2018-08-01
CN108026590A (zh) 2018-05-11
CN108026590B (zh) 2023-10-31
US20180216184A1 (en) 2018-08-02
CN211582764U (zh) 2020-09-29
EP3353319B1 (en) 2020-10-21
CA2999614C (en) 2023-02-28
GB201516975D0 (en) 2015-11-11
CA2999614A1 (en) 2017-03-30

Similar Documents

Publication Publication Date Title
EP3353318B1 (en) Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells
JP2018529346A (ja) 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２
EP3353321B1 (en) Mvd as epigenetic marker for the identification of cd56+ nk cells
CN111295452A (zh) 用于鉴定免疫细胞特别是嗜碱性粒细胞的作为表观遗传标志物的mcc
US11725243B2 (en) Epigenetic method for the identification of follicular T-helper-(TFH-) cells
EP3669001B1 (en) Amplicon region as epigenetic marker for the identification of non-classical monocytes
EP3669003B1 (en) Pdcd1 as epigenetic marker for the identification of immune cells, in particular pd1+ cells
CA3080060C (en) Pdcd1 as epigenetic marker for the identification of immune cells, in particular pd1+ cells
CA2999611C (en) Lrp5 as epigenetic marker for the identification of immune cells, in particular b-cells
HK1257582B (en) Park2 as epigenetic marker for the identification of immune cells, in particular monocytes
EP3802879A1 (en) Cxcr3 as epigenetic marker for the identification of inflammatory immune cells, in particular cd8+ memory t cells
CA3082261A1 (en) Ergic1 as epigenetic marker for the identification of immune cells, in particular monocytic myeloid-derived suppressor cells (mmdscs)

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190919

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20190919

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20200728

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20200722

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20210309