CA2999614C - Park2 as epigenetic marker for the identification of immune cells, in particular monocytes - Google Patents
Park2 as epigenetic marker for the identification of immune cells, in particular monocytes Download PDFInfo
- Publication number
- CA2999614C CA2999614C CA2999614A CA2999614A CA2999614C CA 2999614 C CA2999614 C CA 2999614C CA 2999614 A CA2999614 A CA 2999614A CA 2999614 A CA2999614 A CA 2999614A CA 2999614 C CA2999614 C CA 2999614C
- Authority
- CA
- Canada
- Prior art keywords
- monocytes
- methylation
- cells
- cpg
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Mechanical Control Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1516975.8A GB201516975D0 (en) | 2015-09-25 | 2015-09-25 | PARK2 as epigenetic marker for the identification of immune cells, in particular monocytes |
| GB1516975.8 | 2015-09-25 | ||
| PCT/EP2016/072594 WO2017050925A1 (en) | 2015-09-25 | 2016-09-22 | Park2 as epigenetic marker for the identification of immune cells, in particular monocytes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2999614A1 CA2999614A1 (en) | 2017-03-30 |
| CA2999614C true CA2999614C (en) | 2023-02-28 |
Family
ID=54544104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2999614A Active CA2999614C (en) | 2015-09-25 | 2016-09-22 | Park2 as epigenetic marker for the identification of immune cells, in particular monocytes |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11761041B2 (https=) |
| EP (1) | EP3353319B1 (https=) |
| JP (1) | JP2018529346A (https=) |
| CN (2) | CN108026590B (https=) |
| CA (1) | CA2999614C (https=) |
| GB (1) | GB201516975D0 (https=) |
| WO (1) | WO2017050925A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017125013B4 (de) * | 2017-10-25 | 2019-10-17 | Epiontis Gmbh | MCC als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere basophiler Granulozyten |
| DE102017125150B4 (de) * | 2017-10-26 | 2019-10-10 | Epiontis Gmbh | Endosialin (CD248) als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere naïver CD8+ T-Zellen |
| DE102017125335B4 (de) | 2017-10-27 | 2019-10-17 | Epiontis Gmbh | Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten |
| HK1256212A2 (zh) * | 2018-12-27 | 2019-09-13 | 汪恩光 | 拉动式的换挡传动系统及食物料理机 |
| JPWO2022191293A1 (https=) * | 2021-03-12 | 2022-09-15 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2367012T3 (es) * | 2006-02-28 | 2011-10-27 | Charite-Universitätsmedizin Berlin | Detección y control de calidad de linfocitos t reguladores a través del análisis de metilación del adn del gen foxp3. |
| CA2671270A1 (en) * | 2006-12-29 | 2008-07-17 | Asuragen, Inc. | Mir-16 regulated genes and pathways as targets for therapeutic intervention |
| PL2248913T3 (pl) * | 2009-04-28 | 2017-04-28 | Epiontis Gmbh | GNLY jako marker epigenetyczny do identyfikacji komórek naturalnej cytotoksyczności ekspresjonujących CD56 |
| WO2011128820A2 (en) * | 2010-04-16 | 2011-10-20 | Koninklijke Philips Electronics N.V. | Methods for the analysis of breast cancer disorders |
| WO2013033627A2 (en) * | 2011-09-01 | 2013-03-07 | The Regents Of The University Of California | Diagnosis and treatment of arthritis using epigenetics |
| WO2013067451A2 (en) * | 2011-11-04 | 2013-05-10 | Population Diagnostics Inc. | Methods and compositions for diagnosing, prognosing, and treating neurological conditions |
| JP6590790B2 (ja) * | 2013-04-19 | 2019-10-16 | エピオンティス ゲーエムベーハー | 生体サンプルにおける定量的細胞組成を特定する方法 |
-
2015
- 2015-09-25 GB GBGB1516975.8A patent/GB201516975D0/en not_active Ceased
-
2016
- 2016-09-22 US US15/752,060 patent/US11761041B2/en active Active
- 2016-09-22 EP EP16770027.7A patent/EP3353319B1/en active Active
- 2016-09-22 CA CA2999614A patent/CA2999614C/en active Active
- 2016-09-22 CN CN201680052663.5A patent/CN108026590B/zh active Active
- 2016-09-22 JP JP2018515530A patent/JP2018529346A/ja active Pending
- 2016-09-22 WO PCT/EP2016/072594 patent/WO2017050925A1/en not_active Ceased
-
2019
- 2019-08-28 CN CN201921407627.3U patent/CN211582764U/zh not_active Withdrawn - After Issue
Also Published As
| Publication number | Publication date |
|---|---|
| HK1257582A1 (en) | 2019-10-25 |
| US11761041B2 (en) | 2023-09-19 |
| WO2017050925A1 (en) | 2017-03-30 |
| EP3353319A1 (en) | 2018-08-01 |
| CN108026590A (zh) | 2018-05-11 |
| JP2018529346A (ja) | 2018-10-11 |
| CN108026590B (zh) | 2023-10-31 |
| US20180216184A1 (en) | 2018-08-02 |
| CN211582764U (zh) | 2020-09-29 |
| EP3353319B1 (en) | 2020-10-21 |
| GB201516975D0 (en) | 2015-11-11 |
| CA2999614A1 (en) | 2017-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20190927 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20240910 |
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| U11 | Full renewal or maintenance fee paid |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 9TH ANNIV.) - STANDARD Year of fee payment: 9 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250917 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250917 |