JP2018527570A5 - - Google Patents

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Publication number
JP2018527570A5
JP2018527570A5 JP2018511233A JP2018511233A JP2018527570A5 JP 2018527570 A5 JP2018527570 A5 JP 2018527570A5 JP 2018511233 A JP2018511233 A JP 2018511233A JP 2018511233 A JP2018511233 A JP 2018511233A JP 2018527570 A5 JP2018527570 A5 JP 2018527570A5
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JP
Japan
Prior art keywords
peripheral blood
cells
positive
combination
patient
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JP2018511233A
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English (en)
Japanese (ja)
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JP2018527570A (ja
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Priority claimed from PCT/US2016/050274 external-priority patent/WO2017041043A1/en
Publication of JP2018527570A publication Critical patent/JP2018527570A/ja
Publication of JP2018527570A5 publication Critical patent/JP2018527570A5/ja
Priority to JP2021173852A priority Critical patent/JP7206352B2/ja
Withdrawn legal-status Critical Current

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JP2018511233A 2015-09-02 2016-09-02 併用療法のための患者の選択 Withdrawn JP2018527570A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021173852A JP7206352B2 (ja) 2015-09-02 2021-10-25 併用療法のための患者の選択

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562213288P 2015-09-02 2015-09-02
US62/213,288 2015-09-02
US201562219612P 2015-09-16 2015-09-16
US62/219,612 2015-09-16
PCT/US2016/050274 WO2017041043A1 (en) 2015-09-02 2016-09-02 Selection of patients for combination therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021173852A Division JP7206352B2 (ja) 2015-09-02 2021-10-25 併用療法のための患者の選択

Publications (2)

Publication Number Publication Date
JP2018527570A JP2018527570A (ja) 2018-09-20
JP2018527570A5 true JP2018527570A5 (https=) 2019-12-12

Family

ID=58188549

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018511233A Withdrawn JP2018527570A (ja) 2015-09-02 2016-09-02 併用療法のための患者の選択
JP2021173852A Active JP7206352B2 (ja) 2015-09-02 2021-10-25 併用療法のための患者の選択

Family Applications After (1)

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JP2021173852A Active JP7206352B2 (ja) 2015-09-02 2021-10-25 併用療法のための患者の選択

Country Status (14)

Country Link
US (2) US11397184B2 (https=)
EP (1) EP3345002A4 (https=)
JP (2) JP2018527570A (https=)
KR (2) KR102631377B1 (https=)
CN (2) CN108139403B (https=)
AU (2) AU2016318136B2 (https=)
BR (1) BR112018003238A2 (https=)
CA (1) CA2994731C (https=)
HK (1) HK1258128A1 (https=)
IL (1) IL257355B (https=)
MX (1) MX2018002640A (https=)
RU (1) RU2018111407A (https=)
WO (1) WO2017041043A1 (https=)
ZA (1) ZA201800931B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018508593A (ja) * 2015-03-20 2018-03-29 シンダックス ファーマシューティカルズ,インコーポレイティド がんを処置するためのhdac阻害剤および抗pd−1抗体の組合せ
RU2018130831A (ru) 2016-01-28 2020-03-02 Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн Применение ингибиторов деацетилаз гистонов для улучшения иммунотерапии
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
GB2567093A (en) 2016-07-15 2019-04-03 Viracta Therapeutics Inc Histone deacetylase inhibitors for use in immunotherapy
WO2018213665A1 (en) 2017-05-19 2018-11-22 Syndax Pharmaceuticals, Inc. Combination therapies
AU2019266231B2 (en) * 2018-05-07 2025-08-21 Syndax Pharmaceuticals, Inc. Selection of patients for combination therapy
CN109251891B (zh) * 2018-09-21 2021-10-22 苏州大学附属第一医院 一种cd40联合pd-l1及细胞因子扩增pbmc的方法
CN117054649A (zh) * 2023-08-04 2023-11-14 广州中医药大学第一附属医院 一种慢性萎缩性胃炎向胃癌转化标志物及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328245A (en) 1981-02-13 1982-05-04 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4410545A (en) 1981-02-13 1983-10-18 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4409239A (en) 1982-01-21 1983-10-11 Syntex (U.S.A.) Inc. Propylene glycol diester solutions of PGE-type compounds
US6350458B1 (en) 1998-02-10 2002-02-26 Generex Pharmaceuticals Incorporated Mixed micellar drug deliver system and method of preparation
ITUD20080058A1 (it) * 2008-03-18 2009-09-19 Thankstem S R L Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali
GB201015765D0 (en) 2010-09-21 2010-10-27 Immatics Biotechnologies Gmbh Use of myeloid cell biomarkers for the diagnosis of cancer
EP3682896A1 (en) * 2011-04-28 2020-07-22 University of Southern California Human myeloid derived suppressor cell cancer markers
CN103906837A (zh) 2011-09-02 2014-07-02 辛达克斯制药股份有限公司 治疗乳腺癌的方法
CA2878815A1 (en) * 2012-07-10 2014-01-16 Dana-Farber Cancer Institue, Inc. Anti-proliferative compounds and uses thereof
CA2886650A1 (en) 2012-11-29 2014-06-05 The Penn State Research Foundation Photodynamic dhsip anticancer therapeutic and immunomodulator
US10869926B2 (en) * 2014-07-15 2020-12-22 The Johns Hopkins University Suppression of myeloid derived suppressor cells and immune checkpoint blockade
JP2018508593A (ja) * 2015-03-20 2018-03-29 シンダックス ファーマシューティカルズ,インコーポレイティド がんを処置するためのhdac阻害剤および抗pd−1抗体の組合せ

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