JP2018526352A5 - - Google Patents
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- Publication number
- JP2018526352A5 JP2018526352A5 JP2018506301A JP2018506301A JP2018526352A5 JP 2018526352 A5 JP2018526352 A5 JP 2018526352A5 JP 2018506301 A JP2018506301 A JP 2018506301A JP 2018506301 A JP2018506301 A JP 2018506301A JP 2018526352 A5 JP2018526352 A5 JP 2018526352A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- substituted
- optionally
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SMXLVZARNMVEKM-FJFCPSMQSA-N Cc1cc(OC2CCOCC2)cc(C)c1-c(cc1)c(CCC2CNc3ncc([C@@H](C4)[C@H]4C(O)=O)cc3)c2c1F Chemical compound Cc1cc(OC2CCOCC2)cc(C)c1-c(cc1)c(CCC2CNc3ncc([C@@H](C4)[C@H]4C(O)=O)cc3)c2c1F SMXLVZARNMVEKM-FJFCPSMQSA-N 0.000 description 1
- WUEFBSDYTXRVSZ-VJQNXJLFSA-N Cc1cc(OCC2COCC2)cc(C)c1-c(c(CC1)c2C1Nc1ncc([C@@H](C3)[C@H]3C(O)=O)cc1)ccc2F Chemical compound Cc1cc(OCC2COCC2)cc(C)c1-c(c(CC1)c2C1Nc1ncc([C@@H](C3)[C@H]3C(O)=O)cc1)ccc2F WUEFBSDYTXRVSZ-VJQNXJLFSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15180175 | 2015-08-07 | ||
| EP15180175.0 | 2015-08-07 | ||
| EP15199739 | 2015-12-14 | ||
| EP15199739.2 | 2015-12-14 | ||
| PCT/EP2016/068291 WO2017025368A1 (en) | 2015-08-07 | 2016-08-01 | Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018526352A JP2018526352A (ja) | 2018-09-13 |
| JP2018526352A5 true JP2018526352A5 (cg-RX-API-DMAC7.html) | 2020-11-05 |
| JP6816107B2 JP6816107B2 (ja) | 2021-01-20 |
Family
ID=56618142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018506301A Expired - Fee Related JP6816107B2 (ja) | 2015-08-07 | 2016-08-01 | インダニルアミノピリジルシクロプロパンカルボン酸、医薬組成物及びこれらの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9617251B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3331860B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6816107B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017025368A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10125101B2 (en) | 2016-11-28 | 2018-11-13 | Boehringer Ingelheim International Gmbh | Indanylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| CN110214135B (zh) * | 2017-01-26 | 2023-02-21 | 勃林格殷格翰国际有限公司 | 茚满基氨基吡嗪基环丙烷羧酸、药物组合物及其用途 |
| JOP20180040A1 (ar) * | 2017-04-20 | 2019-01-30 | Gilead Sciences Inc | مثبطات pd-1/pd-l1 |
| CN118084940A (zh) | 2018-02-13 | 2024-05-28 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 |
| MA51232A (fr) | 2018-02-22 | 2020-10-07 | Chemocentryx Inc | Indane-amines utiles en tant qu'antagonistes de pd-l1 |
| US12083118B2 (en) | 2018-03-29 | 2024-09-10 | Arbutus Biopharma Corporation | Substituted 1,1′-biphenyl compounds, analogues thereof, and methods using same |
| AU2019255750B2 (en) | 2018-04-19 | 2021-10-21 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| PE20210642A1 (es) | 2018-07-13 | 2021-03-23 | Gilead Sciences Inc | Inhibidores de pd-1/pd-l1 |
| EP3865477B1 (en) * | 2018-10-10 | 2023-07-12 | Korea Research Institute of Bioscience and Biotechnology | Carbene compound, carbene-metal nanoparticle complex and preparation method thereof |
| CN112955435B (zh) | 2018-10-24 | 2024-09-06 | 吉利德科学公司 | Pd-1/pd-l1抑制剂 |
| IL291985A (en) | 2019-10-07 | 2022-06-01 | Kallyope Inc | Gpr119 agonists |
| PH12022552277A1 (en) | 2020-02-28 | 2024-03-04 | Kallyope Inc | Gpr40 agonists |
| UY39222A (es) | 2020-05-19 | 2021-11-30 | Kallyope Inc | Activadores de la ampk |
| EP4172162A4 (en) | 2020-06-26 | 2024-08-07 | Kallyope, Inc. | AMPK ACTIVATORS |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003277576A1 (en) * | 2002-11-08 | 2004-06-07 | Takeda Pharmaceutical Company Limited | Receptor function controlling agent |
| EP1726580A4 (en) * | 2004-03-15 | 2008-02-13 | Takeda Pharmaceutical | AMINOPHNYLPROPANO ACID DERIVATIVE |
| EP1924546A1 (en) * | 2005-09-14 | 2008-05-28 | Amgen, Inc | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| US8633182B2 (en) * | 2012-05-30 | 2014-01-21 | Boehringer Ingelheim International Gmbh | Indanyloxyphenylcyclopropanecarboxylic acids |
| WO2015024526A1 (en) * | 2013-08-23 | 2015-02-26 | Fujian Haixi Pharmaceuticals Co., Ltd | Carboxylic acid compounds in treatment of diabetes mellitus |
-
2016
- 2016-08-01 US US15/225,038 patent/US9617251B2/en active Active
- 2016-08-01 WO PCT/EP2016/068291 patent/WO2017025368A1/en not_active Ceased
- 2016-08-01 JP JP2018506301A patent/JP6816107B2/ja not_active Expired - Fee Related
- 2016-08-01 EP EP16750134.5A patent/EP3331860B1/en active Active