JP2018524008A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018524008A5 JP2018524008A5 JP2018501936A JP2018501936A JP2018524008A5 JP 2018524008 A5 JP2018524008 A5 JP 2018524008A5 JP 2018501936 A JP2018501936 A JP 2018501936A JP 2018501936 A JP2018501936 A JP 2018501936A JP 2018524008 A5 JP2018524008 A5 JP 2018524008A5
- Authority
- JP
- Japan
- Prior art keywords
- candidate
- neoantigens
- peptide
- neoantigen
- candidate neoantigens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562192373P | 2015-07-14 | 2015-07-14 | |
| US62/192,373 | 2015-07-14 | ||
| PCT/US2016/042288 WO2017011660A1 (en) | 2015-07-14 | 2016-07-14 | Neoantigen analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018524008A JP2018524008A (ja) | 2018-08-30 |
| JP2018524008A5 true JP2018524008A5 (https=) | 2019-08-15 |
Family
ID=57757739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018501936A Pending JP2018524008A (ja) | 2015-07-14 | 2016-07-14 | ネオアンチゲン分析 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10563266B2 (https=) |
| EP (2) | EP3323070B1 (https=) |
| JP (1) | JP2018524008A (https=) |
| CN (1) | CN108351916A (https=) |
| CA (2) | CA3255210A1 (https=) |
| WO (1) | WO2017011660A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016128060A1 (en) * | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| GB201516047D0 (en) | 2015-09-10 | 2015-10-28 | Cancer Rec Tech Ltd | Method |
| US11514289B1 (en) | 2016-03-09 | 2022-11-29 | Freenome Holdings, Inc. | Generating machine learning models using genetic data |
| JP7155470B2 (ja) * | 2017-03-31 | 2022-10-19 | エーシーティー ジェノミックス （アイピー） カンパニー リミテッド | 免疫原性がん特異的エピトープのためのランク付けシステム |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| EP3688165A4 (en) | 2017-09-25 | 2021-09-29 | Nant Holdings IP, LLC | VALIDATION OF THE PRESENTATION OF NEOEPITOPES |
| CN108388773B (zh) * | 2018-02-01 | 2019-11-19 | 杭州纽安津生物科技有限公司 | 一种肿瘤新生抗原的鉴定方法 |
| CN108491689B (zh) * | 2018-02-01 | 2019-07-09 | 杭州纽安津生物科技有限公司 | 基于转录组的肿瘤新抗原鉴定方法 |
| CN108796055B (zh) * | 2018-06-12 | 2022-04-08 | 深圳裕策生物科技有限公司 | 基于二代测序的肿瘤新生抗原检测方法、装置和存储介质 |
| EP3815091A4 (en) * | 2018-06-29 | 2022-03-23 | Rady Children's Hospital Research Center | Method and system for sample identity assurance |
| EP3618071A1 (en) * | 2018-08-28 | 2020-03-04 | CeCaVa GmbH & Co. KG | Methods for selecting tumor-specific neoantigens |
| US20250046393A9 (en) * | 2018-08-28 | 2025-02-06 | CeCaVa GmbH & Co. KG | Methods for ranking and/or selecting tumor-specific neoantigens |
| CN112771214B (zh) * | 2018-09-27 | 2025-06-13 | 耐考德治疗股份有限公司 | 用于选择新表位的方法 |
| SG11202103243PA (en) * | 2018-11-15 | 2021-04-29 | Nouscom Ag | Selection of cancer mutations for generation of a personalized cancer vaccine |
| CA3120200A1 (en) | 2018-11-15 | 2020-05-22 | Personal Genome Diagnostics Inc. | Method of improving prediction of response for cancer patients treated with immunotherapy |
| CN109706065A (zh) * | 2018-12-29 | 2019-05-03 | 深圳裕策生物科技有限公司 | 肿瘤新生抗原负荷检测装置及存储介质 |
| CN109801678B (zh) * | 2019-01-25 | 2023-07-25 | 上海鲸舟基因科技有限公司 | 基于全转录组的肿瘤抗原预测方法及其应用 |
| CN111696628A (zh) * | 2019-03-15 | 2020-09-22 | 痕准生物科技有限公司 | 新生抗原的鉴定方法 |
| CN111755067A (zh) * | 2019-03-28 | 2020-10-09 | 格源致善(上海)生物科技有限公司 | 一种肿瘤新生抗原的筛选方法 |
| WO2020221783A1 (en) * | 2019-04-29 | 2020-11-05 | Vaccibody As | Methods for pre-selection of neoepitopes |
| CN110600077B (zh) * | 2019-08-29 | 2022-07-12 | 北京优迅医学检验实验室有限公司 | 肿瘤新抗原的预测方法及其应用 |
| CN110706742B (zh) * | 2019-09-30 | 2020-06-30 | 中生康元生物科技(北京)有限公司 | 泛癌种肿瘤新生抗原高通量预测方法及其应用 |
| EP4062177A1 (en) * | 2019-11-18 | 2022-09-28 | Epivax Therapeutics, Inc. | Improved compositions and methods for shared neo-epitope vaccines |
| CN114929899B (zh) * | 2020-01-07 | 2026-03-10 | 韩国科学技术院 | 一种新抗原的筛选方法、系统及其用途 |
| GB202006760D0 (en) * | 2020-05-07 | 2020-06-24 | Univ Helsinki | Bioinformatics |
| CN112309502B (zh) * | 2020-10-14 | 2024-09-20 | 深圳市新合生物医疗科技有限公司 | 一种计算肿瘤新抗原负荷的方法及系统 |
| JP2024508677A (ja) * | 2021-02-05 | 2024-02-28 | アマゾン テクノロジーズ インコーポレイテッド | 個別化がんワクチン用ネオアンチゲンのランク付け |
| EP4330380A1 (en) | 2021-04-30 | 2024-03-06 | Tigen Pharma SA | Single vessel expansion of lymphocytes |
| US12537072B1 (en) | 2021-05-27 | 2026-01-27 | Amazon Technologies, Inc. | Immunogenic response prediction based on major histocompatibility complex (MHC) data |
| US20220383996A1 (en) * | 2021-05-27 | 2022-12-01 | Amazon Technologies, Inc. | Assigning peptides to peptide groups for vaccine development |
| US12518851B2 (en) * | 2021-09-07 | 2026-01-06 | Nec Corporation | Binding peptide generation for MHC class I proteins with deep reinforcement learning for immunotherapy decision making |
| JP2025541604A (ja) | 2022-11-02 | 2025-12-22 | ティゲン・ファーマ・ソシエテ・アノニム | リンパ球の拡大 |
| WO2024261339A1 (en) | 2023-06-23 | 2024-12-26 | Tigen Pharma Sa | Lymphocyte-stimulatory matrix (lsm) and uses thereof for expansion of lymphocyte populations |
| WO2025049577A2 (en) * | 2023-08-29 | 2025-03-06 | Foundation Medicine, Inc. | Neoantigen feature selection for prioritization of potential immunotherapy targets |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US454A (en) | 1837-11-04 | Method obi constructing stoves | ||
| US5583024A (en) | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6054276A (en) | 1998-02-23 | 2000-04-25 | Macevicz; Stephen C. | DNA restriction site mapping |
| US6223128B1 (en) | 1998-06-29 | 2001-04-24 | Dnstar, Inc. | DNA sequence assembly system |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| GB9901475D0 (en) | 1999-01-22 | 1999-03-17 | Pyrosequencing Ab | A method of DNA sequencing |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| WO2001023610A2 (en) | 1999-09-29 | 2001-04-05 | Solexa Ltd. | Polynucleotide sequencing |
| US7809509B2 (en) | 2001-05-08 | 2010-10-05 | Ip Genesis, Inc. | Comparative mapping and assembly of nucleic acid sequences |
| WO2005042781A2 (en) | 2003-10-31 | 2005-05-12 | Agencourt Personal Genomics Corporation | Methods for producing a paired tag from a nucleic acid sequence and methods of use thereof |
| US7601499B2 (en) | 2005-06-06 | 2009-10-13 | 454 Life Sciences Corporation | Paired end sequencing |
| US7329860B2 (en) | 2005-11-23 | 2008-02-12 | Illumina, Inc. | Confocal imaging methods and apparatus |
| CA2651796A1 (en) * | 2006-02-27 | 2007-09-07 | Arizona Board Of Regents For And On Behalf Of Arizona State University | Identification and use of novopeptides for the treatment of cancer |
| CN100428254C (zh) * | 2006-07-20 | 2008-10-22 | 上海交通大学 | 交叉反应抗原计算机辅助筛选的方法 |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| US7835871B2 (en) | 2007-01-26 | 2010-11-16 | Illumina, Inc. | Nucleic acid sequencing system and method |
| WO2008098014A2 (en) | 2007-02-05 | 2008-08-14 | Applied Biosystems, Llc | System and methods for indel identification using short read sequencing |
| US8271206B2 (en) | 2008-04-21 | 2012-09-18 | Softgenetics Llc | DNA sequence assembly methods of short reads |
| US20110257889A1 (en) | 2010-02-24 | 2011-10-20 | Pacific Biosciences Of California, Inc. | Sequence assembly and consensus sequence determination |
| BR112012029066A2 (pt) * | 2010-05-14 | 2020-09-01 | The General Hospital Corporation | composições e processos de identificação de neoantígenos específicos de tumor. |
| US10501801B2 (en) * | 2012-09-28 | 2019-12-10 | University Of Connecticut | Identification of tumor-protective epitopes for the treatment of cancers |
-
2016
- 2016-07-14 EP EP16825179.1A patent/EP3323070B1/en active Active
- 2016-07-14 CA CA3255210A patent/CA3255210A1/en active Pending
- 2016-07-14 JP JP2018501936A patent/JP2018524008A/ja active Pending
- 2016-07-14 WO PCT/US2016/042288 patent/WO2017011660A1/en not_active Ceased
- 2016-07-14 CA CA2992578A patent/CA2992578C/en active Active
- 2016-07-14 EP EP24167053.8A patent/EP4407622A3/en active Pending
- 2016-07-14 CN CN201680050906.1A patent/CN108351916A/zh active Pending
- 2016-07-14 US US15/210,489 patent/US10563266B2/en active Active
-
2019
- 2019-12-31 US US16/731,724 patent/US12331361B2/en active Active
-
2025
- 2025-05-12 US US19/205,975 patent/US20250270656A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018524008A5 (https=) | ||
| JP2023134542A5 (https=) | ||
| JP6953515B2 (ja) | 天然の内因性又は外因性細胞プロセシング、輸送及び主要組織適合遺伝子複合体（ｍｈｃ）提示と正の関連性がある特徴量を含むペプチドを同定するための機械学習アルゴリズム | |
| JP2025094018A5 (https=) | ||
| JP2021503897A5 (https=) | ||
| Paul et al. | Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes | |
| Stranzl et al. | NetCTLpan: pan-specific MHC class I pathway epitope predictions | |
| JP2017534257A5 (https=) | ||
| JP2022502416A5 (https=) | ||
| IL274799B2 (en) | Reducing junction epitope presentation for neoantigens | |
| JP2018524008A (ja) | ネオアンチゲン分析 | |
| JP2020510698A5 (https=) | ||
| JP2020518083A5 (https=) | ||
| JP2017532544A5 (https=) | ||
| CN115298739A (zh) | 利用肽序列及hla等位基因序列来预测新生抗原的方法及计算机程序 | |
| JP2020518083A (ja) | 免疫原性がん特異的エピトープのためのランク付けシステム | |
| Harjanto et al. | Clustering HLA class I superfamilies using structural interaction patterns | |
| CN115747327A (zh) | 涉及移码突变的新抗原预测方法 | |
| Dieng et al. | Genetic variations of Plasmodium falciparum circumsporozoite protein and the impact on interactions with human immunoproteins and malaria vaccine efficacy | |
| JP6353894B2 (ja) | Ｋｉｒ及びｈｌａ遺伝子型に基づいて同種造血細胞ドナーを選択するための方法及びアルゴリズム | |
| JP2026065000A (ja) | 免疫原性応答を誘発すると予測される１つ又は複数のソースタンパク質の１つ又は複数の候補領域を識別する方法及びシステム並びにワクチンを作製する方法 | |
| Moyer et al. | Clinical outcomes of HLA‐DPB 1 mismatches in 10/10 HLA‐matched unrelated donor‐recipient pairs undergoing allogeneic stem cell transplant | |
| KR20220151388A (ko) | 펩타이드 신물질 탐색 방법 및 시스템 | |
| Kong et al. | Improved prediction of allergenicity by combination of multiple sequence motifs | |
| Rockberg et al. | Prediction of antibody response using recombinant human protein fragments as antigen |