JP2018524008A5 - - Google Patents
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- JP2018524008A5 JP2018524008A5 JP2018501936A JP2018501936A JP2018524008A5 JP 2018524008 A5 JP2018524008 A5 JP 2018524008A5 JP 2018501936 A JP2018501936 A JP 2018501936A JP 2018501936 A JP2018501936 A JP 2018501936A JP 2018524008 A5 JP2018524008 A5 JP 2018524008A5
- Authority
- JP
- Japan
- Prior art keywords
- candidate
- neoantigens
- peptide
- neoantigen
- candidate neoantigens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562192373P | 2015-07-14 | 2015-07-14 | |
| US62/192,373 | 2015-07-14 | ||
| PCT/US2016/042288 WO2017011660A1 (en) | 2015-07-14 | 2016-07-14 | Neoantigen analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018524008A JP2018524008A (ja) | 2018-08-30 |
| JP2018524008A5 true JP2018524008A5 (https=) | 2019-08-15 |
Family
ID=57757739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018501936A Pending JP2018524008A (ja) | 2015-07-14 | 2016-07-14 | ネオアンチゲン分析 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US10563266B2 (https=) |
| EP (2) | EP3323070B1 (https=) |
| JP (1) | JP2018524008A (https=) |
| CN (2) | CN108351916A (https=) |
| CA (2) | CA3255210A1 (https=) |
| WO (1) | WO2017011660A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016128060A1 (en) * | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| GB201516047D0 (en) | 2015-09-10 | 2015-10-28 | Cancer Rec Tech Ltd | Method |
| US11514289B1 (en) | 2016-03-09 | 2022-11-29 | Freenome Holdings, Inc. | Generating machine learning models using genetic data |
| JP7155470B2 (ja) * | 2017-03-31 | 2022-10-19 | エーシーティー ジェノミックス （アイピー） カンパニー リミテッド | 免疫原性がん特異的エピトープのためのランク付けシステム |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| EP3688165A4 (en) | 2017-09-25 | 2021-09-29 | Nant Holdings IP, LLC | VALIDATION OF THE PRESENTATION OF NEOEPITOPES |
| CN108491689B (zh) * | 2018-02-01 | 2019-07-09 | 杭州纽安津生物科技有限公司 | 基于转录组的肿瘤新抗原鉴定方法 |
| CN108388773B (zh) * | 2018-02-01 | 2019-11-19 | 杭州纽安津生物科技有限公司 | 一种肿瘤新生抗原的鉴定方法 |
| CN108796055B (zh) * | 2018-06-12 | 2022-04-08 | 深圳裕策生物科技有限公司 | 基于二代测序的肿瘤新生抗原检测方法、装置和存储介质 |
| EP3815091A4 (en) * | 2018-06-29 | 2022-03-23 | Rady Children's Hospital Research Center | Method and system for sample identity assurance |
| EP3618071A1 (en) * | 2018-08-28 | 2020-03-04 | CeCaVa GmbH & Co. KG | Methods for selecting tumor-specific neoantigens |
| EP3844776A1 (en) | 2018-08-28 | 2021-07-07 | CeCaVa GmbH & Co. KG | Methods for ranking and/or selecting tumor-specific neoantigens |
| MX2021003654A (es) * | 2018-09-27 | 2021-05-28 | Nykode Therapeutics AS | Metodo para seleccionar neoepitopes. |
| MX2021005656A (es) * | 2018-11-15 | 2021-07-07 | Nouscom Ag | Seleccion de mutaciones de cancer para la generacion de una vacuna contra cancer personalizada. |
| JP7623281B2 (ja) | 2018-11-15 | 2025-01-28 | パーソナル ゲノム ダイアグノスティクス インコーポレイテッド | 免疫療法で治療されたがん患者の応答の予測を改善する方法 |
| CN109706065A (zh) * | 2018-12-29 | 2019-05-03 | 深圳裕策生物科技有限公司 | 肿瘤新生抗原负荷检测装置及存储介质 |
| CN109801678B (zh) * | 2019-01-25 | 2023-07-25 | 上海鲸舟基因科技有限公司 | 基于全转录组的肿瘤抗原预测方法及其应用 |
| CN111696628A (zh) * | 2019-03-15 | 2020-09-22 | 痕准生物科技有限公司 | 新生抗原的鉴定方法 |
| CN111755067A (zh) * | 2019-03-28 | 2020-10-09 | 格源致善(上海)生物科技有限公司 | 一种肿瘤新生抗原的筛选方法 |
| WO2020221783A1 (en) * | 2019-04-29 | 2020-11-05 | Vaccibody As | Methods for pre-selection of neoepitopes |
| CN110600077B (zh) * | 2019-08-29 | 2022-07-12 | 北京优迅医学检验实验室有限公司 | 肿瘤新抗原的预测方法及其应用 |
| CN110706742B (zh) * | 2019-09-30 | 2020-06-30 | 中生康元生物科技(北京)有限公司 | 泛癌种肿瘤新生抗原高通量预测方法及其应用 |
| JP2023522512A (ja) * | 2019-11-18 | 2023-05-31 | エピヴァックス セラピューティクス インコーポレイテッド | 共通のネオエピトープワクチンのための改善された組成物及び方法 |
| JP7617574B2 (ja) * | 2020-01-07 | 2025-01-20 | コリア アドバンスド インスティテュート オブ サイエンス アンド テクノロジー | 新生抗原をスクリーニングする方法、システム及びその用途 |
| GB202006760D0 (en) * | 2020-05-07 | 2020-06-24 | Univ Helsinki | Bioinformatics |
| CN112309502B (zh) * | 2020-10-14 | 2024-09-20 | 深圳市新合生物医疗科技有限公司 | 一种计算肿瘤新抗原负荷的方法及系统 |
| WO2022170067A1 (en) * | 2021-02-05 | 2022-08-11 | Amazon Technologies, Inc. | Ranking neoantigens for personalized cancer vaccine |
| JP2024517793A (ja) | 2021-04-30 | 2024-04-23 | ティゲン・ファーマ・ソシエテ・アノニム | 単一容器リンパ球拡大 |
| US20220383996A1 (en) * | 2021-05-27 | 2022-12-01 | Amazon Technologies, Inc. | Assigning peptides to peptide groups for vaccine development |
| US12537072B1 (en) | 2021-05-27 | 2026-01-27 | Amazon Technologies, Inc. | Immunogenic response prediction based on major histocompatibility complex (MHC) data |
| US12518851B2 (en) * | 2021-09-07 | 2026-01-06 | Nec Corporation | Binding peptide generation for MHC class I proteins with deep reinforcement learning for immunotherapy decision making |
| WO2024097864A1 (en) | 2022-11-02 | 2024-05-10 | Tigen Pharma Sa | Expansion of lymphocytes |
| WO2024261339A1 (en) | 2023-06-23 | 2024-12-26 | Tigen Pharma Sa | Lymphocyte-stimulatory matrix (lsm) and uses thereof for expansion of lymphocyte populations |
| WO2025049577A2 (en) * | 2023-08-29 | 2025-03-06 | Foundation Medicine, Inc. | Neoantigen feature selection for prioritization of potential immunotherapy targets |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US454A (en) | 1837-11-04 | Method obi constructing stoves | ||
| US5583024A (en) | 1985-12-02 | 1996-12-10 | The Regents Of The University Of California | Recombinant expression of Coleoptera luciferase |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| US6054276A (en) | 1998-02-23 | 2000-04-25 | Macevicz; Stephen C. | DNA restriction site mapping |
| US6223128B1 (en) | 1998-06-29 | 2001-04-24 | Dnstar, Inc. | DNA sequence assembly system |
| US6787308B2 (en) | 1998-07-30 | 2004-09-07 | Solexa Ltd. | Arrayed biomolecules and their use in sequencing |
| GB9901475D0 (en) | 1999-01-22 | 1999-03-17 | Pyrosequencing Ab | A method of DNA sequencing |
| US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
| AU7537200A (en) | 1999-09-29 | 2001-04-30 | Solexa Ltd. | Polynucleotide sequencing |
| US7809509B2 (en) | 2001-05-08 | 2010-10-05 | Ip Genesis, Inc. | Comparative mapping and assembly of nucleic acid sequences |
| US20060024681A1 (en) | 2003-10-31 | 2006-02-02 | Agencourt Bioscience Corporation | Methods for producing a paired tag from a nucleic acid sequence and methods of use thereof |
| CA2615323A1 (en) | 2005-06-06 | 2007-12-21 | 454 Life Sciences Corporation | Paired end sequencing |
| US7329860B2 (en) | 2005-11-23 | 2008-02-12 | Illumina, Inc. | Confocal imaging methods and apparatus |
| JP2009532664A (ja) * | 2006-02-27 | 2009-09-10 | アリゾナ・ボード・オブ・リージェンツ・フォー・アンド・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティ | 癌の治療のためのノボペプチドの同定および使用 |
| CN100428254C (zh) * | 2006-07-20 | 2008-10-22 | 上海交通大学 | 交叉反应抗原计算机辅助筛选的方法 |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| EP2126766A2 (en) | 2007-01-26 | 2009-12-02 | Illumina Inc. | Image data efficient genetic sequencing method and system |
| US8165821B2 (en) | 2007-02-05 | 2012-04-24 | Applied Biosystems, Llc | System and methods for indel identification using short read sequencing |
| US8271206B2 (en) | 2008-04-21 | 2012-09-18 | Softgenetics Llc | DNA sequence assembly methods of short reads |
| US20110257889A1 (en) | 2010-02-24 | 2011-10-20 | Pacific Biosciences Of California, Inc. | Sequence assembly and consensus sequence determination |
| EP2569633B1 (en) * | 2010-05-14 | 2016-02-10 | The General Hospital Corporation | Compositions and methods of identifying tumor specific neoantigens |
| LT2901341T (lt) | 2012-09-28 | 2019-09-25 | The University Of Connecticut | Protekcinių vėžio epitopų identifikavimas, skirtas vėžio gydymui |
-
2016
- 2016-07-14 EP EP16825179.1A patent/EP3323070B1/en active Active
- 2016-07-14 CA CA3255210A patent/CA3255210A1/en active Pending
- 2016-07-14 CA CA2992578A patent/CA2992578C/en active Active
- 2016-07-14 CN CN201680050906.1A patent/CN108351916A/zh active Pending
- 2016-07-14 US US15/210,489 patent/US10563266B2/en active Active
- 2016-07-14 EP EP24167053.8A patent/EP4407622A3/en active Pending
- 2016-07-14 CN CN202511758884.1A patent/CN121963858A/zh active Pending
- 2016-07-14 JP JP2018501936A patent/JP2018524008A/ja active Pending
- 2016-07-14 WO PCT/US2016/042288 patent/WO2017011660A1/en not_active Ceased
-
2019
- 2019-12-31 US US16/731,724 patent/US12331361B2/en active Active
-
2025
- 2025-05-12 US US19/205,975 patent/US20250270656A1/en active Pending
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