JP2018523471A5 - - Google Patents
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- JP2018523471A5 JP2018523471A5 JP2018502006A JP2018502006A JP2018523471A5 JP 2018523471 A5 JP2018523471 A5 JP 2018523471A5 JP 2018502006 A JP2018502006 A JP 2018502006A JP 2018502006 A JP2018502006 A JP 2018502006A JP 2018523471 A5 JP2018523471 A5 JP 2018523471A5
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- cysteine
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562193531P | 2015-07-16 | 2015-07-16 | |
| US62/193,531 | 2015-07-16 | ||
| PCT/US2016/042645 WO2017011803A1 (en) | 2015-07-16 | 2016-07-15 | Cysteine-substituted immunoglobulins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018523471A JP2018523471A (ja) | 2018-08-23 |
| JP2018523471A5 true JP2018523471A5 (https=) | 2019-08-29 |
Family
ID=56550419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502006A Withdrawn JP2018523471A (ja) | 2015-07-16 | 2016-07-15 | システイン置換免疫グロブリン |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20180312592A1 (https=) |
| EP (1) | EP3322449A1 (https=) |
| JP (1) | JP2018523471A (https=) |
| CN (1) | CN108025092A (https=) |
| AU (1) | AU2016293606A1 (https=) |
| CA (1) | CA2992539A1 (https=) |
| HK (1) | HK1255234A1 (https=) |
| WO (1) | WO2017011803A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108290955A (zh) * | 2015-11-24 | 2018-07-17 | 塞勒兰特治疗公司 | 人源化抗-cll-1抗体 |
| CN108367043A (zh) | 2015-12-04 | 2018-08-03 | 西雅图基因公司 | 季铵化的微管溶素化合物的缀合物 |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| CA3023143A1 (en) | 2016-06-15 | 2017-12-21 | Icahn School Of Medicine At Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
| BR112018076306A2 (pt) | 2016-06-17 | 2019-03-26 | Magenta Therapeutics, Inc. | composições e métodos para a supressão de células cd117+ |
| MX395639B (es) | 2017-01-20 | 2025-03-25 | Heidelberg Pharma Res Gmbh | Composiciones y métodos para el agotamiento de células cd137+. |
| SG11201907299XA (en) | 2017-02-08 | 2019-09-27 | Dragonfly Therapeutics Inc | Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer |
| IL268755B2 (en) | 2017-02-20 | 2025-12-01 | Dragonfly Therapeutics Inc | Proteins that bind her2, nkg2d, and cd16 |
| WO2018187706A2 (en) | 2017-04-07 | 2018-10-11 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| JP7073487B2 (ja) * | 2017-06-16 | 2022-05-23 | イーライ リリー アンド カンパニー | 操作された抗体化合物およびこれらの抱合体 |
| AU2018288030B2 (en) * | 2017-06-20 | 2022-02-03 | Systimmune, Inc. | Screening of fixed-point coupling sites of cysteine-modified antibody-toxin conjugate (TDC) |
| DK3749346T3 (da) | 2018-02-08 | 2024-09-09 | Dragonfly Therapeutics Inc | Antistof variable domænekombinationer rettet mod nkg2d-receptoren |
| EA202091887A1 (ru) | 2018-02-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Комбинированная терапия рака с применением мультиспецифических связывающих белков, которые активируют естественные клетки-киллеры |
| JOP20200268A1 (ar) * | 2018-06-01 | 2020-10-26 | Eisai R&D Man Co Ltd | تضفير مترافقات عقار جسم مضاد معدل وطرق استخدامها |
| EP3810634A4 (en) | 2018-06-21 | 2022-07-27 | Icahn School of Medicine at Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| US12378318B2 (en) | 2018-08-08 | 2025-08-05 | Dragonfly Therapeutics, Inc. | Proteins binding NKG2D, CD16 and a tumor-associated antigen |
| WO2020033630A1 (en) | 2018-08-08 | 2020-02-13 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| TW202021618A (zh) | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | 抗ｉｌ１ｒａｐ抗體及其使用方法 |
| EP3959216A4 (en) * | 2019-04-24 | 2023-01-11 | Icahn School of Medicine at Mount Sinai | ANTI-INFLUENZA B VIRUS NEURAMINIDASE ANTIBODIES AND USES THEREOF |
| EP4045537A4 (en) * | 2019-10-15 | 2024-07-17 | Dragonfly Therapeutics, Inc. | Antibodies targeting flt3 and use thereof |
| MX2022004430A (es) * | 2019-10-15 | 2022-07-19 | Dragonfly Therapeutics Inc | Proteinas que se unen al receptor activador de celulas asesinas naturales grupo 2 miembro d (nkg2d), al cumulo de diferenciacion 16 (cd16) y a la tirosina cinasa 3 similar a fms (flt3). |
| CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
| JP2024508894A (ja) | 2021-03-03 | 2024-02-28 | ドラゴンフライ セラピューティクス， インコーポレイテッド | Ｎｋｇ２ｄ、ｃｄ１６、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法 |
| KR20250031149A (ko) | 2022-06-30 | 2025-03-06 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
| WO2025103355A1 (zh) * | 2023-11-14 | 2025-05-22 | 信达生物制药(苏州)有限公司 | 抗egfr和her3双特异性抗体-药物偶联物及其用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008070593A2 (en) * | 2006-12-01 | 2008-06-12 | Seattle Genetics, Inc. | Variant target binding agents and uses thereof |
| CA2763935A1 (en) * | 2009-06-04 | 2010-12-09 | Novartis Ag | Methods for identification of sites for igg conjugation |
| AU2011215684A1 (en) * | 2010-02-12 | 2012-08-30 | Research Corporation Technologies | Multimeric proteins comprising immunoglobulin constant domains |
| US9163090B2 (en) * | 2012-05-07 | 2015-10-20 | Cellerant Therapeutics, Inc. | Antibodies specific for CLL-1 |
-
2016
- 2016-07-15 HK HK18114363.0A patent/HK1255234A1/zh unknown
- 2016-07-15 US US15/745,351 patent/US20180312592A1/en not_active Abandoned
- 2016-07-15 WO PCT/US2016/042645 patent/WO2017011803A1/en not_active Ceased
- 2016-07-15 EP EP16742567.7A patent/EP3322449A1/en not_active Withdrawn
- 2016-07-15 CA CA2992539A patent/CA2992539A1/en not_active Abandoned
- 2016-07-15 AU AU2016293606A patent/AU2016293606A1/en not_active Abandoned
- 2016-07-15 CN CN201680052410.8A patent/CN108025092A/zh not_active Withdrawn
- 2016-07-15 JP JP2018502006A patent/JP2018523471A/ja not_active Withdrawn
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