JP2018523471A5 - - Google Patents
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- JP2018523471A5 JP2018523471A5 JP2018502006A JP2018502006A JP2018523471A5 JP 2018523471 A5 JP2018523471 A5 JP 2018523471A5 JP 2018502006 A JP2018502006 A JP 2018502006A JP 2018502006 A JP2018502006 A JP 2018502006A JP 2018523471 A5 JP2018523471 A5 JP 2018523471A5
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- cysteine
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562193531P | 2015-07-16 | 2015-07-16 | |
| US62/193,531 | 2015-07-16 | ||
| PCT/US2016/042645 WO2017011803A1 (en) | 2015-07-16 | 2016-07-15 | Cysteine-substituted immunoglobulins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018523471A JP2018523471A (ja) | 2018-08-23 |
| JP2018523471A5 true JP2018523471A5 (https=) | 2019-08-29 |
Family
ID=56550419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018502006A Withdrawn JP2018523471A (ja) | 2015-07-16 | 2016-07-15 | システイン置換免疫グロブリン |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20180312592A1 (https=) |
| EP (1) | EP3322449A1 (https=) |
| JP (1) | JP2018523471A (https=) |
| CN (1) | CN108025092A (https=) |
| AU (1) | AU2016293606A1 (https=) |
| CA (1) | CA2992539A1 (https=) |
| HK (1) | HK1255234A1 (https=) |
| WO (1) | WO2017011803A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1258375A1 (zh) | 2015-11-24 | 2019-11-08 | Onk Therapeutics Limited | 人源化抗-cll-1抗体 |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| KR20180090290A (ko) | 2015-12-04 | 2018-08-10 | 시애틀 지네틱스, 인크. | 사차화 튜불리신 화합물들의 컨쥬게이트들 |
| MX2018015755A (es) | 2016-06-15 | 2019-08-29 | Icahn School Med Mount Sinai | Proteinas de hemaglutinina de virus de influenza y usos de las mismas. |
| IL263744B2 (en) | 2016-06-17 | 2023-11-01 | Magenta Therapeutics Inc | Compositions and methods for the depletion of cd117 plus cells |
| EP3571230A4 (en) | 2017-01-20 | 2020-12-16 | Magenta Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR DELETION OF CD137 + CELLS |
| AU2018219887B2 (en) | 2017-02-08 | 2024-08-15 | Dragonfly Therapeutics, LLC | Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer |
| CN110944661A (zh) | 2017-02-20 | 2020-03-31 | 蜻蜓疗法股份有限公司 | 结合her2、nkg2d和cd16的蛋白质 |
| US11254733B2 (en) | 2017-04-07 | 2022-02-22 | Icahn School Of Medicine At Mount Sinai | Anti-influenza B virus neuraminidase antibodies and uses thereof |
| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| US20200155702A1 (en) * | 2017-06-16 | 2020-05-21 | Eli Lilly And Company | Engineered Antibody Compounds and Conjuates Thereof |
| AU2018288030B2 (en) * | 2017-06-20 | 2022-02-03 | Systimmune, Inc. | Screening of fixed-point coupling sites of cysteine-modified antibody-toxin conjugate (TDC) |
| CA3237846A1 (en) | 2018-02-08 | 2019-08-15 | Dragonfly Therapeutics, Inc. | Antibody variable domains targeting the nkg2d receptor |
| BR112020015994A2 (pt) | 2018-02-08 | 2020-12-15 | Dragonfly Therapeutics, Inc. | Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer |
| CN119405832A (zh) * | 2018-06-01 | 2025-02-11 | 卫材R&D管理有限公司 | 剪接调节抗体-药物缀合物及其使用方法 |
| CA3104297A1 (en) | 2018-06-21 | 2019-12-26 | Icahn School Of Medicine At Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| EP3833392A4 (en) | 2018-08-08 | 2022-05-18 | Dragonfly Therapeutics, Inc. | MULTISPECIFIC BINDING PROTEINS FOR BINDING CD33, NKG2D AND CD16 AND METHODS OF USE |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| KR102835308B1 (ko) | 2018-08-08 | 2025-07-21 | 드래곤플라이 쎄라퓨틱스, 인크. | Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질 |
| TW202021618A (zh) | 2018-08-17 | 2020-06-16 | 美商２３與我有限公司 | 抗ｉｌ１ｒａｐ抗體及其使用方法 |
| US12545718B2 (en) | 2019-04-24 | 2026-02-10 | Icahn School Of Medicine At Mount Sinai | Anti-influenza B virus neuraminidase antibodies and uses thereof |
| AU2020366000A1 (en) * | 2019-10-15 | 2022-05-12 | Dragonfly Therapeutics, Inc. | Antibodies targeting FLT3 and use thereof |
| PE20221316A1 (es) * | 2019-10-15 | 2022-09-07 | Dragonfly Therapeutics Inc | Proteinas que se unen a nkg2d, cd16 y flt3 |
| CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
| EP4301774A4 (en) | 2021-03-03 | 2025-08-13 | Dragonfly Therapeutics Inc | METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN |
| EP4548932A1 (en) | 2022-06-30 | 2025-05-07 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
| WO2025103355A1 (zh) * | 2023-11-14 | 2025-05-22 | 信达生物制药(苏州)有限公司 | 抗egfr和her3双特异性抗体-药物偶联物及其用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2099823E (pt) * | 2006-12-01 | 2014-12-22 | Seattle Genetics Inc | Agentes de ligação ao alvo variantes e suas utilizações |
| MX2011012665A (es) * | 2009-06-04 | 2012-03-07 | Novartis Ag | Metodos para identificacion de sitios para conjugacion de igg. |
| EP2533811A4 (en) * | 2010-02-12 | 2013-12-25 | Res Corp Technologies Inc | MULTIMETER PROTEINS WITH IMMUNE LOBULIN CONSTANTS DOMAINS |
| US9163090B2 (en) * | 2012-05-07 | 2015-10-20 | Cellerant Therapeutics, Inc. | Antibodies specific for CLL-1 |
-
2016
- 2016-07-15 WO PCT/US2016/042645 patent/WO2017011803A1/en not_active Ceased
- 2016-07-15 JP JP2018502006A patent/JP2018523471A/ja not_active Withdrawn
- 2016-07-15 US US15/745,351 patent/US20180312592A1/en not_active Abandoned
- 2016-07-15 EP EP16742567.7A patent/EP3322449A1/en not_active Withdrawn
- 2016-07-15 CN CN201680052410.8A patent/CN108025092A/zh not_active Withdrawn
- 2016-07-15 HK HK18114363.0A patent/HK1255234A1/zh unknown
- 2016-07-15 AU AU2016293606A patent/AU2016293606A1/en not_active Abandoned
- 2016-07-15 CA CA2992539A patent/CA2992539A1/en not_active Abandoned
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