JP2018523105A5 - - Google Patents
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- JP2018523105A5 JP2018523105A5 JP2017563088A JP2017563088A JP2018523105A5 JP 2018523105 A5 JP2018523105 A5 JP 2018523105A5 JP 2017563088 A JP2017563088 A JP 2017563088A JP 2017563088 A JP2017563088 A JP 2017563088A JP 2018523105 A5 JP2018523105 A5 JP 2018523105A5
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- Japan
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- therapeutic compound
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562170099P | 2015-06-02 | 2015-06-02 | |
| US62/170,099 | 2015-06-02 | ||
| US201562237905P | 2015-10-06 | 2015-10-06 | |
| US62/237,905 | 2015-10-06 | ||
| PCT/US2016/035198 WO2016196580A1 (en) | 2015-06-02 | 2016-06-01 | Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018523105A JP2018523105A (ja) | 2018-08-16 |
| JP2018523105A5 true JP2018523105A5 (https=) | 2019-05-16 |
| JP6585737B2 JP6585737B2 (ja) | 2019-10-02 |
Family
ID=57441615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563088A Active JP6585737B2 (ja) | 2015-06-02 | 2016-06-01 | セレブロン関連タンパク質の比を使用してがんの治療のための薬物の有効性を決定するための方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10338077B2 (https=) |
| EP (1) | EP3304076A4 (https=) |
| JP (1) | JP6585737B2 (https=) |
| WO (1) | WO2016196580A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL278381B2 (en) | 2013-12-06 | 2024-08-01 | Celgene Corp | Methods for determining the effectiveness of a drug for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancer |
| CA2999179A1 (en) | 2015-09-25 | 2017-03-30 | Celgene Corporation | Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs |
| CA3010801A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
| EP3422002B1 (de) | 2017-06-26 | 2020-04-08 | Bioscientia Institut für Medizinische Diagnostik GmbH | Screeningverfahren zur diagnose einer hämatologischen neoplasie |
| TWI793151B (zh) | 2017-08-23 | 2023-02-21 | 瑞士商諾華公司 | 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途 |
| AR116109A1 (es) | 2018-07-10 | 2021-03-31 | Novartis Ag | Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos |
| DK3820573T3 (da) | 2018-07-10 | 2023-10-23 | Novartis Ag | 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidin-2,6-dion-derivativer og anvendelse deraf ved behandling af ikaros family zinc finger 2 (ikzf2)-afhængige sygdomme |
| KR20210071049A (ko) * | 2018-10-04 | 2021-06-15 | 알프레드 헬스 | 치료에 대한 반응을 모니터링하는 방법 |
| US12227488B2 (en) | 2018-12-03 | 2025-02-18 | Dana-Farber Cancer Institute, Inc. | Small molecule degraders of Helios and methods of use |
| KR20210106437A (ko) * | 2018-12-20 | 2021-08-30 | 노파르티스 아게 | 3-(1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체를 포함하는 투약 요법 및 약학적 조합물 |
| US11366101B1 (en) | 2020-12-31 | 2022-06-21 | Elephas Biosciences Corporation | Ex vivo systems and methods for determining the effect of a drug or other agent on a tissue |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012229333B2 (en) * | 2011-03-11 | 2016-12-22 | Mayo Foundation For Medical Education And Research | Methods and materials for assessing responsiveness to lenalidomide, thalidomide, and/or other thalidomide analogs |
| CA2834535A1 (en) | 2011-04-29 | 2012-11-01 | Celgene Corporation | Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor |
| ES2872967T3 (es) * | 2012-06-29 | 2021-11-03 | Celgene Corp | Métodos para determinar la eficacia de fármacos usando IKZF3 (AIOLOS) |
| MX2015003114A (es) * | 2012-09-10 | 2015-07-06 | Celgene Corp | Metodos para el tratamiento de cancer de mama localmente avanzado. |
| TW201534305A (zh) * | 2013-05-03 | 2015-09-16 | Celgene Corp | 使用組合療法治療癌症之方法 |
| IL278381B2 (en) | 2013-12-06 | 2024-08-01 | Celgene Corp | Methods for determining the effectiveness of a drug for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancer |
| KR20160090390A (ko) | 2013-12-06 | 2016-07-29 | 셀진 코포레이션 | 혈액암의 치료방법 및 바이오마커를 사용한 레날리도마이드에 대한 임상적 민감도의 예측방법 |
| WO2016060702A1 (en) | 2014-10-13 | 2016-04-21 | Celgene Corporaton | Methods for treating solid tumors and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| WO2017024019A1 (en) | 2015-08-04 | 2017-02-09 | Celgene Corporation | Methods for treating chronic lymphocytic leukemia and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| WO2017027672A1 (en) | 2015-08-12 | 2017-02-16 | Celgene Corporation | Methods for treating solid tumors and the use of biomarkers as a predictor of clinical sensitivity to immunomodulatory therapies |
| CA2999179A1 (en) | 2015-09-25 | 2017-03-30 | Celgene Corporation | Methods for treating diffuse large b-cell lymphoma and the use of biomarkers as a predictor of responsiveness to drugs |
| CA3010801A1 (en) | 2016-01-08 | 2017-07-13 | Celgene Corporation | Methods for treating cancer and the use of biomarkers as a predictor of clinical sensitivity to therapies |
-
2016
- 2016-06-01 WO PCT/US2016/035198 patent/WO2016196580A1/en not_active Ceased
- 2016-06-01 JP JP2017563088A patent/JP6585737B2/ja active Active
- 2016-06-01 EP EP16804297.6A patent/EP3304076A4/en active Pending
- 2016-06-01 US US15/170,789 patent/US10338077B2/en active Active
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