JP2018521956A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018521956A5 JP2018521956A5 JP2017548194A JP2017548194A JP2018521956A5 JP 2018521956 A5 JP2018521956 A5 JP 2018521956A5 JP 2017548194 A JP2017548194 A JP 2017548194A JP 2017548194 A JP2017548194 A JP 2017548194A JP 2018521956 A5 JP2018521956 A5 JP 2018521956A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- group
- optionally
- alkyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562166240P | 2015-05-26 | 2015-05-26 | |
| US62/166,240 | 2015-05-26 | ||
| PCT/US2016/033923 WO2016191424A2 (en) | 2015-05-26 | 2016-05-24 | Novel heteroaromatic silicon-fluoride-acceptors useful for 18f labeling of molecules and biomolecules, and methods of preparing same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021017722A Division JP2021073293A (ja) | 2015-05-26 | 2021-02-05 | 分子および生体分子の18f標識化に有用な新規な複素芳香環フッ化ケイ素アクセプタおよびその調製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018521956A JP2018521956A (ja) | 2018-08-09 |
| JP2018521956A5 true JP2018521956A5 (enExample) | 2019-06-27 |
| JP7266365B2 JP7266365B2 (ja) | 2023-04-28 |
Family
ID=57394170
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017548194A Active JP7266365B2 (ja) | 2015-05-26 | 2016-05-24 | 分子および生体分子の18f標識化に有用な新規な複素芳香環フッ化ケイ素アクセプタおよびその調製方法 |
| JP2021017722A Withdrawn JP2021073293A (ja) | 2015-05-26 | 2021-02-05 | 分子および生体分子の18f標識化に有用な新規な複素芳香環フッ化ケイ素アクセプタおよびその調製方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021017722A Withdrawn JP2021073293A (ja) | 2015-05-26 | 2021-02-05 | 分子および生体分子の18f標識化に有用な新規な複素芳香環フッ化ケイ素アクセプタおよびその調製方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US10800797B2 (enExample) |
| EP (1) | EP3303349B1 (enExample) |
| JP (2) | JP7266365B2 (enExample) |
| CN (1) | CN107667109B (enExample) |
| CA (1) | CA2982269C (enExample) |
| WO (1) | WO2016191424A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7266365B2 (ja) | 2015-05-26 | 2023-04-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 分子および生体分子の18f標識化に有用な新規な複素芳香環フッ化ケイ素アクセプタおよびその調製方法 |
| US11413360B2 (en) * | 2017-07-28 | 2022-08-16 | Technische Universität München | Dual mode radiotracer and—therapeutics |
| WO2019055825A1 (en) | 2017-09-15 | 2019-03-21 | The Regents Of The University Of California | INHIBITION OF AMINOACYLASE 3 (AA3) IN THE TREATMENT OF CANCER |
| EP3917581A1 (en) * | 2019-01-30 | 2021-12-08 | Technische Universität München | Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof |
| WO2020220020A1 (en) * | 2019-04-26 | 2020-10-29 | The Regents Of The University Of California | Silicon-fluoride heteroaromatic systems for applications in positron emission tomography (pet) molecular imaging |
| EP3976562A1 (en) * | 2019-05-24 | 2022-04-06 | Duke University | 18 f-radiolabeled biomolecules |
| US20230202944A1 (en) * | 2020-05-29 | 2023-06-29 | Fuzionaire, Inc. | Methods for Rapid Formation of Chemicals Including Positron Emission Tomography Biomarkers |
| CN119301134A (zh) * | 2022-04-20 | 2025-01-10 | 富齐奥奈尔治疗诊断股份有限公司 | 治疗诊断用的氟化硅杂芳族系统及其方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6972336B2 (en) * | 2002-07-18 | 2005-12-06 | Novartis Ag | N-alkylation of indole derivatives |
| WO2008040441A2 (en) | 2006-10-02 | 2008-04-10 | Bayer Schering Pharma Aktiengesellschaft | Silicon derivatives for pet imaging |
| WO2010075286A1 (en) * | 2008-12-24 | 2010-07-01 | University Of Washington | MOLECULAR ACTIVATORS OF THE Wnt/β-CATENIN PATHWAY |
| AU2011349482A1 (en) * | 2010-12-22 | 2013-07-25 | Ge Healthcare Limited | HER2 binding peptides labeled with aluminium-(18) fluoride complexed by NOTA |
| JP7266365B2 (ja) | 2015-05-26 | 2023-04-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 分子および生体分子の18f標識化に有用な新規な複素芳香環フッ化ケイ素アクセプタおよびその調製方法 |
-
2016
- 2016-05-24 JP JP2017548194A patent/JP7266365B2/ja active Active
- 2016-05-24 WO PCT/US2016/033923 patent/WO2016191424A2/en not_active Ceased
- 2016-05-24 US US15/575,979 patent/US10800797B2/en active Active
- 2016-05-24 CA CA2982269A patent/CA2982269C/en active Active
- 2016-05-24 EP EP16800638.5A patent/EP3303349B1/en active Active
- 2016-05-24 CN CN201680030562.8A patent/CN107667109B/zh active Active
-
2020
- 2020-08-19 US US16/997,240 patent/US11447508B2/en active Active
-
2021
- 2021-02-05 JP JP2021017722A patent/JP2021073293A/ja not_active Withdrawn
-
2022
- 2022-09-19 US US17/933,234 patent/US12371445B2/en active Active
-
2025
- 2025-06-25 US US19/248,601 patent/US20250333425A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018521956A5 (enExample) | ||
| D’Souza et al. | High-yielding aqueous 18F-labeling of peptides via Al18F chelation | |
| Zheng et al. | Sulfur [18F] fluoride exchange click chemistry enabled ultrafast late-stage radiosynthesis | |
| Cleeren et al. | New chelators for low temperature Al18F-labeling of biomolecules | |
| Dubost et al. | Recent advances in synthetic methods for radioiodination | |
| Schirrmacher et al. | Recent developments and trends in 18F-radiochemistry: syntheses and applications | |
| Weineisen et al. | Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancer | |
| Nolting et al. | Molecular imaging probe development: a chemistry perspective | |
| Keliher et al. | High-Yielding, Two-Step 18 F Labeling Strategy for 18F-PARP1 Inhibitors | |
| Liu et al. | Dual mode fluorescent 18F-PET tracers: efficient modular synthesis of rhodamine-[cRGD] 2-[18F]-organotrifluoroborate, rapid, and high yielding one-step 18F-labeling at high specific activity, and correlated in vivo PET imaging and ex vivo fluorescence | |
| US8288604B2 (en) | Method of rapid methylation, kit for preparing PET tracer and method of producing PET tracer | |
| Galliamova et al. | Heterocyclic and open-chain carboranes via transition-metal-free C–H functionalization of mono-and diazine-N-oxides | |
| Glaser et al. | ‘Click labelling’in PET radiochemistry | |
| Kuchar et al. | Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F] SFB in solution and on solid phase: a comparative study | |
| Wang et al. | H2hox: dual-channel oxine-derived acyclic chelating ligand for 68Ga radiopharmaceuticals | |
| Schmidtke et al. | Gallium complexation, stability, and bioconjugation of 1, 4, 7-triazacyclononane derived chelators with azaheterocyclic arms | |
| CA2731645C (en) | Substituted aryl-fluoroborates as imaging agents | |
| JP6968809B2 (ja) | ジアリールヨードニウム塩を使用してヨード−又はアスタトアレーンを合成するための方法 | |
| Le Bihan et al. | Synthesis of C-functionalized TE1PA and comparison with its analogues. An example of bioconjugation on 9E7. 4 mAb for multiple myeloma 64 Cu-PET imaging | |
| Makarem et al. | HBED-NN: A bifunctional chelator for constructing radiopharmaceuticals | |
| Earley et al. | Charting the chemical and mechanistic scope of light-triggered protein ligation | |
| Narayanam et al. | Rapid one-step 18F-labeling of peptides via heteroaromatic silicon-fluoride acceptors | |
| Zhang et al. | Synthesis, bioconjugation and stability studies of [18F] ethenesulfonyl fluoride | |
| Ramenda et al. | 4-[18F] Fluoro-N-methyl-N-(propyl-2-yn-1-yl) benzenesulfonamide ([18F] F-SA): a versatile building block for labeling of peptides, proteins and oligonucleotides with fluorine-18 via Cu (I)-mediated click chemistry | |
| Taldone et al. | Radiosynthesis of the iodine‐124 labeled Hsp90 inhibitor PU‐H71 |