JP2018520986A - ジチオール粘液溶解剤の新規なプロドラッグ - Google Patents
ジチオール粘液溶解剤の新規なプロドラッグ Download PDFInfo
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- JP2018520986A JP2018520986A JP2017556946A JP2017556946A JP2018520986A JP 2018520986 A JP2018520986 A JP 2018520986A JP 2017556946 A JP2017556946 A JP 2017556946A JP 2017556946 A JP2017556946 A JP 2017556946A JP 2018520986 A JP2018520986 A JP 2018520986A
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- 0 C*[C@]1C(C)ICC1C Chemical compound C*[C@]1C(C)ICC1C 0.000 description 12
- AWYMFBJJKFTCFO-UHFFFAOYSA-N C(C1)C2C1CCC2 Chemical compound C(C1)C2C1CCC2 AWYMFBJJKFTCFO-UHFFFAOYSA-N 0.000 description 1
- RCQIMYPTLFQWFX-JTQLQIEISA-N C=C([C@H](CC1C[IH]C1)N)C1CC1 Chemical compound C=C([C@H](CC1C[IH]C1)N)C1CC1 RCQIMYPTLFQWFX-JTQLQIEISA-N 0.000 description 1
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US201562155078P | 2015-04-30 | 2015-04-30 | |
| US62/155,078 | 2015-04-30 | ||
| PCT/US2016/029729 WO2016176423A1 (en) | 2015-04-30 | 2016-04-28 | Novel prodrugs of dithiol mucolytic agents |
Publications (2)
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| JP2018520986A true JP2018520986A (ja) | 2018-08-02 |
| JP2018520986A5 JP2018520986A5 (https=) | 2019-06-06 |
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| AU (1) | AU2016255851A1 (https=) |
| CA (1) | CA2984424A1 (https=) |
| WO (1) | WO2016176423A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| MX368243B (es) | 2013-08-23 | 2019-09-25 | Parion Sciences Inc | Agentes mucolíticos de ditiol. |
| CA2974210A1 (en) | 2015-01-30 | 2016-08-04 | Parion Sciences, Inc. | Novel monothiol mucolytic agents |
| EP3849620A4 (en) | 2018-09-10 | 2022-08-17 | The Regents of the University of California | DITHIOL SACCHARIDE MUCOLYTICS AND USES THEREOF |
| CN110333302A (zh) * | 2019-06-25 | 2019-10-15 | 武汉兴华智慧医药科技有限公司 | 乙酰半胱氨酸溶液中n,n-二乙酰基羊毛硫氨酸的检测方法 |
| EP3797783A1 (en) | 2019-09-27 | 2021-03-31 | Freie Universität Berlin | Novel medical uses of thiol-functionalized polyglycerol derivatives |
| WO2021231397A1 (en) | 2020-05-13 | 2021-11-18 | The Regents Of The University Of California | Thiosaccharides for use in treating coronavirus infection |
| CN117982422B (zh) * | 2024-04-03 | 2024-07-26 | 深圳大佛药业股份有限公司 | 一种用于治疗鼻炎的喷雾剂 |
| EP4717268A1 (en) | 2024-09-30 | 2026-04-01 | Freie Universität Berlin | Particularly appropriate thiol-functionalized polyglycerol derivatives and their medical uses |
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-
2016
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- 2016-04-28 CN CN201680034915.1A patent/CN107708680A/zh active Pending
- 2016-04-28 EP EP16713720.7A patent/EP3288548A4/en not_active Withdrawn
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- 2016-04-28 WO PCT/US2016/029729 patent/WO2016176423A1/en not_active Ceased
- 2016-04-28 JP JP2017556946A patent/JP2018520986A/ja active Pending
- 2016-05-02 US US15/144,288 patent/US10526283B2/en not_active Expired - Fee Related
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| JP2014518268A (ja) * | 2011-06-27 | 2014-07-28 | パリオン・サイエンシィズ・インコーポレーテッド | 3,5−ジアミノ−6−クロロ−n−(n−(4−(4−(2−(ヘキシル(2,3,4,5,6−ペンタヒドロキシヘキシル)アミノ)エトキシ)フェニル)ブチル)カルバミミドイル)ピラジン−2−カルボキサミド |
| WO2014084898A1 (en) * | 2012-11-28 | 2014-06-05 | Yansong Lu | Novel synthetic antioxidants and their uses |
| WO2015026601A2 (en) * | 2013-08-23 | 2015-02-26 | Johnson Michael R | Dithiol mucolytic agents |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2016176423A1 (en) | 2016-11-03 |
| EP3288548A1 (en) | 2018-03-07 |
| CA2984424A1 (en) | 2016-11-03 |
| CN107708680A (zh) | 2018-02-16 |
| EP3288548A4 (en) | 2018-10-31 |
| AU2016255851A1 (en) | 2017-12-14 |
| US10526283B2 (en) | 2020-01-07 |
| US20160318861A1 (en) | 2016-11-03 |
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