JP2018515623A5 - - Google Patents
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- Publication number
- JP2018515623A5 JP2018515623A5 JP2018512823A JP2018512823A JP2018515623A5 JP 2018515623 A5 JP2018515623 A5 JP 2018515623A5 JP 2018512823 A JP2018512823 A JP 2018512823A JP 2018512823 A JP2018512823 A JP 2018512823A JP 2018515623 A5 JP2018515623 A5 JP 2018515623A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- nhc
- cancer
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CN(C(*)*=C(**C(N(*)C(*)(*N)I[Al])=O)C1)C=*1*=C Chemical compound CN(C(*)*=C(**C(N(*)C(*)(*N)I[Al])=O)C1)C=*1*=C 0.000 description 5
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562163369P | 2015-05-18 | 2015-05-18 | |
| US62/163,369 | 2015-05-18 | ||
| US201562203070P | 2015-08-10 | 2015-08-10 | |
| US62/203,070 | 2015-08-10 | ||
| PCT/US2016/033111 WO2016187324A1 (en) | 2015-05-18 | 2016-05-18 | Heterocyclic compounds as kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018515623A JP2018515623A (ja) | 2018-06-14 |
| JP2018515623A5 true JP2018515623A5 (https=) | 2019-06-27 |
Family
ID=57320732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018512823A Withdrawn JP2018515623A (ja) | 2015-05-18 | 2016-05-18 | キナーゼ阻害剤としての複素環式化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10392402B2 (https=) |
| EP (1) | EP3297437A4 (https=) |
| JP (1) | JP2018515623A (https=) |
| CN (1) | CN107835637A (https=) |
| AU (1) | AU2016264220A1 (https=) |
| CA (1) | CA3024113A1 (https=) |
| HK (1) | HK1248070A1 (https=) |
| IL (1) | IL255750A (https=) |
| WO (1) | WO2016187324A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210069016A1 (en) * | 2008-11-13 | 2021-03-11 | Gholam A. Peyman | Neurodegenerative Disorder Treatment Method |
| CN105980365B (zh) | 2014-02-11 | 2019-06-21 | 拜耳医药股份公司 | 作为mIDH1抑制剂的苯并咪唑-2-胺 |
| AU2015217788B2 (en) | 2014-02-11 | 2019-06-27 | Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts | Benzimidazol-2-amines as mIDH1 inhibitors |
| HK1248070A1 (zh) * | 2015-05-18 | 2018-10-12 | 转化药物开发有限责任公司 | 作为激酶抑制剂的杂环化合物 |
| AU2020273376C1 (en) * | 2016-10-24 | 2024-02-29 | Translational Drug Development, Llc | Amide compounds as kinase inhibitors, compositions and methods of treatment |
| US10807966B2 (en) | 2016-11-21 | 2020-10-20 | Translational Drug Development, Llc | Heterocyclic compounds as kinase inhibitors |
| JP7490569B2 (ja) * | 2018-04-24 | 2024-05-27 | トランスレイショナル・ドラッグ・ディベロップメント・エルエルシー | キナーゼ阻害剤としてのアミド化合物、組成物および処置方法 |
| WO2020142745A1 (en) * | 2019-01-04 | 2020-07-09 | Translational Drug Development, Llc | Methods of treating graft versus host disease and neoplastic disease with amide compounds |
| KR20220102622A (ko) * | 2019-11-15 | 2022-07-20 | 우한 엘엘 사이언스 앤드 테크놀로지 디벨롭먼트 컴퍼니, 리미티드 | Rock 억제제 및 이의 제조 방법과 용도 |
| ES3015621T3 (en) | 2019-12-31 | 2025-05-06 | Ind Tech Res Inst | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and use of the same |
| CR20220375A (es) * | 2020-01-07 | 2022-09-22 | Disarm Therapeutics Inc | Inhibidores de sarm1 |
| EP4192828A1 (en) * | 2020-08-04 | 2023-06-14 | Nura Bio, Inc. | Substituted pyridine derivatives as sarm1 inhibitors |
| CN116438171A (zh) | 2020-09-16 | 2023-07-14 | 努拉生物公司 | 作为sarm1抑制剂的取代的吡啶衍生物 |
| MX2024001322A (es) | 2021-07-28 | 2024-04-30 | Nura Bio Inc | Derivados de piridina sustituida como inhibidores de sarm1. |
| KR20240176853A (ko) * | 2023-06-15 | 2024-12-26 | 현대자동차주식회사 | 이중 전원 공급 장치, 그를 포함한 시스템 및 그 방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8211919B2 (en) | 2005-09-02 | 2012-07-03 | Astellas Pharma Inc. | Amide derivatives as rock inhibitors |
| CA2709883A1 (en) * | 2007-12-19 | 2009-06-25 | The Scripps Research Institute | Benzimidazoles and analogs as rho kinase inhibitors |
| WO2009126635A1 (en) | 2008-04-09 | 2009-10-15 | Abbott Laboratories | 2-amino-benzothiazole derivates useful as inhibitors of rock kinases |
| US20130129677A1 (en) * | 2009-02-27 | 2013-05-23 | Siga Technologies, Inc. | Thienopyridine Derivatives for the Treatment and Prevention of Dengue Virus Infections |
| AR078793A1 (es) * | 2009-10-27 | 2011-12-07 | Orion Corp | Derivados de carboxamidas no esteroidales y acil hidrazona moduladores de receptores androgenicos de tejido selectivo (sarm), composiciones farmaceuticas que los contienen y uso de los mismos en el tratamiento del cancer de prostata entre otros |
| WO2011130740A2 (en) * | 2010-04-16 | 2011-10-20 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Pyridylthiazole-based ureas as inhibitors of rho associated protein kinase (rock) and methods of use |
| US8697911B2 (en) * | 2010-07-07 | 2014-04-15 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
| WO2012139930A1 (en) * | 2011-04-11 | 2012-10-18 | Nerviano Medical Sciences S.R.L. | Pyrazolyl-pyrimidine derivatives as kinase inhibitors |
| HK1248070A1 (zh) * | 2015-05-18 | 2018-10-12 | 转化药物开发有限责任公司 | 作为激酶抑制剂的杂环化合物 |
-
2016
- 2016-05-18 HK HK18107657.9A patent/HK1248070A1/zh unknown
- 2016-05-18 CN CN201680041168.4A patent/CN107835637A/zh active Pending
- 2016-05-18 CA CA3024113A patent/CA3024113A1/en not_active Abandoned
- 2016-05-18 AU AU2016264220A patent/AU2016264220A1/en not_active Abandoned
- 2016-05-18 WO PCT/US2016/033111 patent/WO2016187324A1/en not_active Ceased
- 2016-05-18 US US15/574,800 patent/US10392402B2/en active Active
- 2016-05-18 EP EP16797227.2A patent/EP3297437A4/en not_active Withdrawn
- 2016-05-18 JP JP2018512823A patent/JP2018515623A/ja not_active Withdrawn
-
2017
- 2017-11-19 IL IL255750A patent/IL255750A/en unknown
-
2019
- 2019-08-26 US US16/551,694 patent/US10633393B2/en active Active
-
2020
- 2020-04-27 US US16/859,977 patent/US20200255448A1/en not_active Abandoned
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